Opportunity Information: Apply for PA 08 129
Apply for PA 08 129
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Prescription Drug Misuse (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Dec 5, 2008 and posted on Apr 3, 2008.
- Applicants must submit their applications by May 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Small businesses Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments County governments City or township governments State governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession
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Opportunity Summary:
The Prescription Drug Misuse (R03) funding opportunity (PA 08-129) is a National Institutes of Health grant program sponsored by the National Institute on Drug Abuse (NIDA) and the National Institute of Mental Health (NIMH) that focuses on reducing the misuse of prescription medications while still supporting their legitimate, appropriate medical use. The central idea is to encourage research that helps prevent and respond to misuse of therapeutic agents that have abuse potential, without undermining access for patients who need these drugs for proper clinical care.
The opportunity invites a wide range of research topics aimed at understanding and addressing prescription drug misuse from multiple angles. On the epidemiology side, NIH is looking for studies that clarify how big the problem is and what it looks like in real-world settings, including patterns of misuse tied to specific drug classes, the physical and mental health consequences, and broader social impacts. It also encourages research that identifies determinants of misuse and maps trajectories over time, such as how initial medical exposure or other risk factors may lead to nonmedical use, escalation, or transition to other substances. In addition, the announcement explicitly welcomes basic science work that examines mechanisms of action at the cellular level, including research that could reveal why certain drugs are reinforcing or dependence-producing, and studies that explore potential ways to block or reduce abuse liability through new pharmacologic strategies or medications. A third major emphasis is health services research, including efforts to improve clinical practices for identifying patients at risk, and the design, testing, and dissemination of prevention and treatment interventions that can work in healthcare and community settings.
This is an R03 mechanism, meaning it is designed for small, short-duration projects that can be completed with limited resources. The announcement highlights the types of projects that fit well under R03, such as pilot and feasibility studies, secondary analyses of existing datasets, small self-contained research projects, and the development of research methods or new research technologies. In practical terms, this mechanism is meant to help investigators generate preliminary findings, test an approach, or build tools and methods that can later support larger-scale work.
The program uses the NIH Small Research Grant (R03) mechanism and runs in parallel with two companion announcements that cover the same scientific scope but use different grant mechanisms: PA 08-127 for R01 applications (typically larger, longer, and more comprehensive projects) and PA 08-128 for R21 applications (often exploratory or developmental research). Applicants can choose the mechanism that best matches the maturity, scale, and resource needs of their project, with PA 08-129 serving as the small-project option.
Funding amounts and the number of awards are not fixed in advance because NIH expects applications to vary significantly in scope, duration, and cost. As a result, the final number and size of awards depend on the mix of mechanisms, the overall quality of applications received, and requested budgets and project periods.
Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants listed include public and private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), small businesses, for-profit entities other than small businesses, and a wide range of government bodies (state, county, city/township, special district governments, and certain housing authorities). The eligibility list also includes tribal governments and tribal organizations, and specifically calls out additional eligible entities such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, faith-based and community-based organizations, regional organizations, U.S. territory or possession agencies, and foreign organizations (non-U.S. entities). There is no cost sharing or matching requirement.
Key administrative details include the funding opportunity number PA 08-129, posting date of April 3, 2008, and a closing date of May 7, 2011 (with an archive date of June 7, 2011). The associated CFDA program areas are 93.242 (Mental Health Research Grants) and 93.279 (Drug Abuse and Addiction Research Programs). The full announcement was made available through NIH, and technical assistance for access or linking issues was directed to the NIH Office of Extramural Research webmaster contact listed in the notice.
FAQs: Prescription Drug Misuse (R03) - NIH (PA 08-129)
What is the Prescription Drug Misuse (R03) funding opportunity?
Prescription Drug Misuse (R03) is a National Institutes of Health (NIH) funding opportunity (PA 08-129) sponsored by the National Institute on Drug Abuse (NIDA) and the National Institute of Mental Health (NIMH). It supports research aimed at reducing the misuse of prescription medications while still supporting legitimate, appropriate medical use for patients who need these therapies.
What is the main goal of PA 08-129?
The central goal is to encourage research that helps prevent and respond to misuse of therapeutic agents with abuse potential, without undermining access for proper clinical care.
Which NIH institutes are sponsoring this opportunity?
This opportunity is sponsored by the National Institute on Drug Abuse (NIDA) and the National Institute of Mental Health (NIMH).
What grant mechanism does this opportunity use?
PA 08-129 uses the NIH Small Research Grant (R03) mechanism, which is intended for small, short-duration projects that can be completed with limited resources.
What kinds of projects are a good fit for an R03 under this announcement?
The announcement highlights several project types that fit well under an R03, including:
- Pilot studies
- Feasibility studies
- Secondary analyses of existing datasets
- Small, self-contained research projects
- Development of research methods
- Development of new research technologies
Overall, the R03 mechanism is positioned to help investigators generate preliminary findings, test an approach, or develop tools and methods that can support later, larger-scale research.
What research topics are encouraged under PA 08-129?
The opportunity invites a wide range of research topics addressing prescription drug misuse from multiple angles. The description emphasizes epidemiology, basic science, and health services research.
What epidemiology topics does NIH emphasize for this opportunity?
On the epidemiology side, NIH encourages studies that clarify the size and characteristics of the problem in real-world settings, including patterns of misuse tied to specific drug classes, physical and mental health consequences, and broader social impacts. It also encourages research on determinants of misuse and trajectories over time (for example, how initial medical exposure or other risk factors may lead to nonmedical use, escalation, or transition to other substances).
Does this opportunity support basic science research?
Yes. The announcement explicitly welcomes basic science work examining mechanisms of action at the cellular level, including studies that may reveal why certain drugs are reinforcing or dependence-producing, and research exploring ways to block or reduce abuse liability through new pharmacologic strategies or medications.
Does this opportunity support health services research?
Yes. A major emphasis is health services research, including improving clinical practices for identifying patients at risk and designing, testing, and disseminating prevention and treatment interventions that can work in healthcare and community settings.
How does this R03 opportunity relate to the companion announcements?
PA 08-129 runs in parallel with companion announcements that cover the same scientific scope but use different grant mechanisms:
- PA 08-127 for R01 applications (typically larger, longer, and more comprehensive projects)
- PA 08-128 for R21 applications (often exploratory or developmental research)
Applicants can choose the mechanism that best matches the maturity, scale, and resource needs of their project, with PA 08-129 serving as the small-project option.
Are the funding amounts and number of awards fixed?
No. Funding amounts and the number of awards are not fixed in advance because NIH expects applications to vary significantly in scope, duration, and cost. The final number and size of awards depend on the mix of mechanisms, the overall quality of applications received, and requested budgets and project periods.
Who is eligible to apply for PA 08-129?
Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants listed include public and private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), small businesses, for-profit entities other than small businesses, and a wide range of government bodies.
Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility list specifically includes foreign organizations (non-U.S. entities).
What types of government entities are eligible?
The eligible applicant types include state governments, county governments, city or township governments, special district governments, certain housing authorities, U.S. territory or possession agencies, and other listed government bodies.
Are tribal governments and tribal organizations eligible?
Yes. The eligibility list includes tribal governments and tribal organizations, and also references Tribally Controlled Colleges and Universities.
Does the eligibility list include specific institution types like HBCUs or Hispanic-serving institutions?
Yes. The announcement specifically calls out additional eligible entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities.
Are faith-based and community-based organizations eligible?
Yes. Faith-based and community-based organizations are specifically included in the eligibility list.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
What is the funding opportunity number for this announcement?
The funding opportunity number is PA 08-129.
When was PA 08-129 posted, and when did it close?
The posting date is April 3, 2008. The closing date is May 7, 2011. The archive date is June 7, 2011.
What CFDA program areas are associated with PA 08-129?
The associated CFDA program areas are 93.242 (Mental Health Research Grants) and 93.279 (Drug Abuse and Addiction Research Programs).
Where was the full announcement made available?
The full announcement was made available through NIH.
Who was listed for technical assistance related to access or linking issues?
Technical assistance for access or linking issues was directed to the NIH Office of Extramural Research webmaster contact listed in the notice.
Browse more opportunities from the same category: Education Health
Next opportunity: Exploratory/Developmental Grant for Complementary and Alternative Medicine (CAM) Studies of Humans (R21)
Previous opportunity: Prescription Drug Misuse (R21)
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 08 129) also looked into and applied for these:
| Funding Opportunity |
|---|
| Exploratory/Developmental Grant for Complementary and Alternative Medicine (CAM) Studies of Humans (R21) Apply for PAR 08 135 Funding Number: PAR 08 135 Agency: National Institutes of Health Category: Education Health Funding Amount: $250,000 |
| Correlative Studies with Specimens from Multi Site Trials (R21) Apply for PA 08 133 Funding Number: PA 08 133 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Correlative Studies with Specimens from Multi Site Trials (R01) Apply for PA 08 134 Funding Number: PA 08 134 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mitochondria in Cancer Epidemiology, Detection, Diagnosis and Prognosis (R01) Apply for PA 08 143 Funding Number: PA 08 143 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mitochondria in Cancer Epidemiology, Detection, Diagnosis and Prognosis (R21) Apply for PA 08 144 Funding Number: PA 08 144 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Science Education Drug Abuse Partnership Award R25 Apply for PAR 08 145 Funding Number: PAR 08 145 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Biomarkers of Infection Associated Cancers (R01) Apply for PA 08 156 Funding Number: PA 08 156 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Biomarkers of Infection Associated Cancers (R21) Apply for PA 08 157 Funding Number: PA 08 157 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Transdisciplinary Research on Fatigue and Fatigability in Aging (R01) Apply for PA 08 161 Funding Number: PA 08 161 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Transdisciplinary Research on Fatigue and Fatigability in Aging (R21) Apply for PA 08 162 Funding Number: PA 08 162 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Stem Cells and Cancer (R21) Apply for PA 08 165 Funding Number: PA 08 165 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Economics of Treatment and Prevention Services for Drug Alcohol Abuse (R03) Apply for PA 08 172 Funding Number: PA 08 172 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Economics of Treatment and Prevention Services for Drug Alcohol Abuse (R01) Apply for PA 08 174 Funding Number: PA 08 174 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Novel Lentiviral Models of HIV Neuropathogenesis (R01) Apply for PAS 08 178 Funding Number: PAS 08 178 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Novel Lentiviral Models of HIV Neuropathogenesis (R21) Apply for PAS 08 179 Funding Number: PAS 08 179 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Exploratory/Developmental Grant for Complementary and Alternative Medicine (CAM) Studies using Cells, Tissues, and Animal Models of Disease (R21) Apply for PA 08 185 Funding Number: PA 08 185 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Medications Development for Polydrug Addiction Treatment (R01) Apply for PAS 08 186 Funding Number: PAS 08 186 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medications Development for Polydrug Addiction Treatment (R21) Apply for PAS 08 187 Funding Number: PAS 08 187 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Integrating Biobehavioral and Sociocultural Research to Prevent HIV Transmission and Infection (R01) Apply for PA 08 188 Funding Number: PA 08 188 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Integrating Biobehavioral and Sociocultural Research to Prevent HIV Transmission and Infection (R21) Apply for PA 08 189 Funding Number: PA 08 189 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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