Opportunity Information: Apply for RFA CE 10 001

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Preventing Unintentional Childhood Injuries (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136 Injury Prevention and Control Research and State and Community Based Programs.
  • This funding opportunity was created on Oct 27, 2009 and posted on Oct 27, 2009.
  • Applicants must submit their applications by Jan 8, 2010 Letter of Intent Receipt Date December 7, 2009 Application Submission Receipt Date January 8, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $525,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $175,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Eligible Institutions You may submit an application(s) if your organization has any of the following characteristics Public nonprofit organizations Private nonprofit organizations For profit organizations Small, minority, and women owned businesses Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized or state recognized American Indian/Alaska Native tribal governments American Indian/Alaska Native tribally designated organizations Alaska Native health corporations Urban Indian health organizations Tribal epidemiology centers State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Political subdivisions of States (in consultation with States) A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If you are applying as a bona fide agent of a state or local government, you must provide a letter from the state or local government as documentation of your status. Attach this documentation behind the first page of your application form or for electronic applications, use a PDF file and attach as Other Documents and label as appropriate.
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Opportunity Summary:

The Preventing Unintentional Childhood Injuries (R21) funding opportunity (RFA CE 10-001) is a Centers for Disease Control and Prevention (CDC) grant designed to strengthen the evidence base for preventing unintentional injuries among children and adolescents ages 0 through 19. The core aim is to support research that can meaningfully reduce childhood injury risk and improve prevention practice, while also building broader capacity in injury prevention and control programs. The announcement is intentionally cross-disciplinary, inviting participation from fields such as epidemiology, community medicine, clinical pediatrics, pediatric psychology, child development, public policy, public health law, and the behavioral and social sciences. In other words, the CDC is looking for projects that do not sit in a single silo, but instead connect data, real-world settings, behavior, systems, and policy to produce practical prevention knowledge.

This FOA aligns with national and CDC priority frameworks, specifically the Healthy People 2010 priority area of injury and violence prevention and the National Center for Injury Prevention and Control (NCIPC) research agenda. It also reflects CDC performance goals around prevention research, with an emphasis on community-based interventions that are sustainable over time and transferable to other communities. The underlying expectation is that funded work will either lay the groundwork for interventions that can be maintained after the grant ends or generate findings that can be adapted and scaled beyond the original study site. The FOA frames this as part of a larger strategy to expand the field’s capacity, meaning the grant is not only about generating new results but also about improving the tools, methods, and approaches available to injury prevention programs.

The mechanism used is the NIH-style R21 exploratory/developmental grant, which is specifically meant for early-stage, concept-testing, and breakthrough-oriented research. R21 projects are often where new ideas are tried, novel partnerships are formed, and emerging methods are piloted before larger, more definitive studies are launched. The CDC highlights that these studies may be “high risk/high reward,” including work that breaks new ground, extends prior discoveries in new directions, or produces new techniques, methodologies, models, or applications. The emphasis is on innovation and forward movement rather than simply repeating established approaches, and the outcomes can be biomedical, behavioral, or clinically relevant, as long as they contribute to preventing unintentional injuries in youth.

From a funding and administrative standpoint, the opportunity is a discretionary grant in the health category (CFDA 93.136, Injury Prevention and Control Research and State and Community Based Programs). The CDC expected to make about three awards under this announcement, with an estimated total funding amount of $525,000. The award ceiling is $175,000, and there is no stated award floor. Cost sharing or matching is not required, which lowers a common barrier for applicants and can make it more feasible for smaller organizations or community partners to participate meaningfully.

Eligibility is broad and includes public and private nonprofit organizations, for-profit organizations, small/minority/women-owned businesses, universities and colleges, research institutions, hospitals, community-based and faith-based organizations, and a wide range of governmental and tribal entities. Eligible public-sector applicants include state and local governments (and their bona fide agents, including U.S. territories and freely associated states listed in the announcement), political subdivisions of states (in consultation with states), and multiple American Indian/Alaska Native governance and health entities such as federally or state recognized tribal governments, tribally designated organizations, Alaska Native health corporations, urban Indian health organizations, tribal epidemiology centers, and related organizations. If applying as a bona fide agent for a state or local government, the applicant must provide documentation (a letter) from the relevant government entity confirming that status, submitted with the application materials.

Key dates for this specific FOA reflect its original 2009-2010 cycle. The opportunity was posted on October 27, 2009. The letter of intent was due December 7, 2009, and the application submission deadline was January 8, 2010, which was also the closing date. The archive date is February 7, 2010, indicating the announcement is no longer active but still useful as a reference point for CDC priorities and the kinds of projects the agency sought under this R21 topic area.

For applicants needing help accessing the full announcement at the time, the FOA listed a CDC Procurement and Grants Office Technical Information Management contact line at 770-488-2700. The announcement also directs readers to Healthy People and the NCIPC research agenda websites for broader context on national injury prevention goals and CDC’s injury research priorities.

Frequently Asked Questions (FAQs)

What is the Preventing Unintentional Childhood Injuries (R21) funding opportunity (RFA CE 10-001)?

It is a Centers for Disease Control and Prevention (CDC) discretionary grant opportunity that used the NIH-style R21 exploratory/developmental research mechanism. The purpose was to strengthen the evidence base for preventing unintentional injuries among children and adolescents ages 0 through 19, with a focus on research that can reduce injury risk and improve prevention practice.

What age group is the grant focused on?

The focus is on children and adolescents ages 0 through 19.

What kinds of injuries are in scope?

The announcement focuses on unintentional childhood injuries. Specific injury types are not listed in the provided information, but the scope is clearly prevention of unintentional injuries affecting youth ages 0 to 19.

What is the main goal of the program?

The core aim is to support research that can meaningfully reduce childhood injury risk and improve prevention practice, while also building broader capacity in injury prevention and control programs.

What does the CDC mean by “building broader capacity” in injury prevention?

Based on the description, the grant was intended not only to generate findings, but also to expand the field's capacity by improving the tools, methods, and approaches available to injury prevention programs.

Is this opportunity intended to be cross-disciplinary?

Yes. The announcement is intentionally cross-disciplinary and invites participation from areas including epidemiology, community medicine, clinical pediatrics, pediatric psychology, child development, public policy, public health law, and the behavioral and social sciences.

What types of projects does the CDC appear to be looking for?

The CDC describes interest in projects that connect data, real-world settings, behavior, systems, and policy to produce practical prevention knowledge, rather than projects that remain within a single disciplinary silo.

How does this FOA connect to national public health priorities?

This FOA aligns with the Healthy People 2010 priority area of injury and violence prevention and the National Center for Injury Prevention and Control (NCIPC) research agenda. It also reflects CDC performance goals around prevention research.

Is there an emphasis on community-based interventions?

Yes. The FOA emphasizes community-based interventions that are sustainable over time and transferable to other communities.

What does “sustainable and transferable” mean in the context of this announcement?

The provided information indicates an expectation that funded work would either lay groundwork for interventions that can be maintained after the grant ends or generate findings that can be adapted and scaled beyond the original study site.

What grant mechanism is used and what does it imply?

The mechanism is the NIH-style R21 exploratory/developmental grant, which is intended for early-stage, concept-testing, and breakthrough-oriented research. It is often used to pilot emerging methods, form novel partnerships, and test new ideas before larger studies.

Are “high risk/high reward” studies allowed or encouraged?

Yes. The CDC highlights that R21 studies may be “high risk/high reward,” including work that breaks new ground, extends prior discoveries in new directions, or produces new techniques, methodologies, models, or applications.

Do project outcomes need to be biomedical?

No. The announcement notes that outcomes can be biomedical, behavioral, or clinically relevant, as long as they contribute to preventing unintentional injuries in youth.

What is the CFDA number and program category for this opportunity?

The CFDA number is 93.136, described as Injury Prevention and Control Research and State and Community Based Programs. The opportunity is categorized as a discretionary grant in the health category.

How many awards did the CDC expect to make under this FOA?

The CDC expected to make about three awards.

What was the estimated total funding available?

The estimated total funding amount was $525,000.

What was the maximum award amount (award ceiling)?

The award ceiling was $175,000.

Was there a minimum award amount (award floor)?

No award floor is stated in the provided information.

Was cost sharing or matching required?

No. Cost sharing or matching was not required.

What types of organizations were eligible to apply?

Eligibility was broad and included public and private nonprofit organizations, for-profit organizations, small/minority/women-owned businesses, universities and colleges, research institutions, hospitals, community-based and faith-based organizations, and a wide range of governmental and tribal entities.

Which government entities were eligible?

Eligible public-sector applicants included state and local governments (and their bona fide agents, including U.S. territories and freely associated states listed in the announcement), political subdivisions of states (in consultation with states), and multiple American Indian/Alaska Native governance and health entities.

Which tribal and American Indian/Alaska Native entities were eligible?

Eligible entities included federally or state recognized tribal governments, tribally designated organizations, Alaska Native health corporations, urban Indian health organizations, tribal epidemiology centers, and related organizations.

What is a “bona fide agent” and what documentation was required?

If applying as a bona fide agent for a state or local government, the applicant had to provide documentation (a letter) from the relevant government entity confirming that status, submitted with the application materials.

What were the key dates for this funding opportunity?

The opportunity was posted on October 27, 2009. The letter of intent was due December 7, 2009. The application submission deadline was January 8, 2010, which was also the closing date. The archive date was February 7, 2010.

Is this funding opportunity still active?

No. The archive date (February 7, 2010) indicates the announcement is no longer active, though it may still be useful as a reference for CDC priorities and the kinds of R21 injury prevention projects the agency sought.

Who was listed as a contact for technical help with the full announcement?

The FOA listed the CDC Procurement and Grants Office Technical Information Management contact line at 770-488-2700 for applicants needing help accessing the full announcement.

Where did the announcement direct readers for additional context on priorities?

It directed readers to Healthy People and the NCIPC research agenda websites for broader context on national injury prevention goals and CDC injury research priorities.

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