Opportunity Information: Apply for RFA HD 12 198

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Prevention of HIV Transmission/Acquisition through a better understanding of Reproductive Health (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on May 19, 2011 and posted on May 19, 2011.
  • Applicants must submit their applications by Aug 11, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $350,000.00 in funding.
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Small businesses Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments State governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Independent school districts Native American tribal governments (Federally recognized) Special district governments For profit organizations other than small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for RFA HD 12 198

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Opportunity Summary:

The grant opportunity titled "Prevention of HIV Transmission/Acquisition through a better understanding of Reproductive Health (R01)" is a National Institutes of Health (NIH) research funding announcement issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It supports Research Project Grant (R01) applications aimed at improving scientific understanding of how reproductive health factors intersect with HIV prevention, specifically in ways that influence HIV acquisition and transmission. The central idea is that gaps in reproductive health knowledge can limit the effectiveness of HIV prevention strategies, so the FOA encourages research that connects these areas to produce clearer, more actionable prevention insights.

The FOA emphasizes comprehensive approaches that blend behavioral and biomedical perspectives. In practice, that means proposals are expected to look beyond a single factor and instead examine how biological mechanisms, sexual and reproductive health conditions, behaviors, and real-world contexts interact to shape HIV risk. The announcement is oriented toward generating new understanding that can inform prevention research and future interventions, rather than simply describing correlations. While the topic area is HIV prevention, the focus is specifically on reproductive health as a lens for identifying mechanisms and opportunities to reduce transmission and acquisition.

This announcement is not meant to fund drug discovery efforts or large-scale clinical trials. Applicants are expected to propose research that fits the R01 scope, typically hypothesis-driven and mechanistic or explanatory in nature, potentially including smaller-scale or preparatory studies where appropriate, but not expansive multi-site efficacy trials or pharmaceutical development pipelines. The intention is to support studies that can clarify pathways of risk and protection and guide the next stages of prevention science.

Administratively, this is a discretionary grant program using the NIH R01 funding mechanism. The Funding Opportunity Number is RFA-HD-12-198, and it falls under CFDA 93.865 (Child Health and Human Development Extramural Research). The opportunity was posted on May 19, 2011, with an original and current closing date of August 11, 2011, and an archive date of September 11, 2011. The estimated total funding available was $2,000,000, with an award ceiling of $350,000, indicating an expectation of multiple awards depending on application quality and budget structure.

Eligibility is broad and includes many organization types across the nonprofit, academic, governmental, and private sectors. Eligible applicants include nonprofits with or without 501(c)(3) status (including community-based and faith-based organizations), small businesses, for-profit organizations other than small businesses, public and private institutions of higher education, and a range of government entities (city or township, county, state, special district governments, and independent school districts). Public housing authorities and Indian housing authorities are also eligible. The FOA explicitly includes tribal governments (federally recognized) and other tribal organizations, as well as tribally controlled colleges and universities (TCCUs). It also allows non-U.S. entities (foreign organizations), regional organizations, U.S. territories or possessions, and designated institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and eligible federal agencies. There is no cost-sharing or matching requirement, which lowers barriers for applicants that may not have access to non-federal matching funds.

For applicants seeking the full official text and application details, NICHD directs users to the NIH guide page associated with the announcement (http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-12-198.html). Technical issues accessing the notice are routed to the NIH Office of Extramural Research (OER) webmaster contact listed in the announcement.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The opportunity is titled "Prevention of HIV Transmission/Acquisition through a better understanding of Reproductive Health (R01)."

Which federal agency and NIH institute are sponsoring this funding opportunity?

This is a National Institutes of Health (NIH) research funding announcement issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

What is the goal of this funding opportunity?

The goal is to support research that improves scientific understanding of how reproductive health factors intersect with HIV prevention in ways that influence HIV acquisition and transmission. The announcement is based on the idea that gaps in reproductive health knowledge can limit the effectiveness of HIV prevention strategies, so it encourages research that connects these areas to produce clearer, more actionable prevention insights.

What type of grant mechanism is being used?

This program uses the NIH Research Project Grant (R01) mechanism.

What kind of studies does the FOA encourage?

The FOA emphasizes comprehensive approaches that blend behavioral and biomedical perspectives. Proposals are expected to look beyond a single factor and examine how biological mechanisms, sexual and reproductive health conditions, behaviors, and real-world contexts interact to shape HIV risk. It is oriented toward generating new understanding that can inform prevention research and future interventions, rather than simply describing correlations.

Is this opportunity focused on HIV prevention in general or a specific aspect of HIV prevention?

It is an HIV prevention opportunity with a specific focus: using reproductive health as a lens for identifying mechanisms and opportunities to reduce HIV transmission and acquisition.

Does the FOA prioritize mechanistic or explanatory research?

Yes. The announcement emphasizes research intended to clarify pathways of risk and protection and guide the next stages of prevention science, rather than only reporting associations.

Are large-scale clinical trials supported under this FOA?

No. The announcement is not meant to fund large-scale clinical trials. Applicants are expected to propose research that fits the R01 scope, which is typically hypothesis-driven and mechanistic or explanatory in nature.

Does this FOA fund drug discovery or pharmaceutical development efforts?

No. The announcement is not meant to fund drug discovery efforts or pharmaceutical development pipelines.

Can smaller-scale or preparatory studies be appropriate?

Yes. The FOA notes that smaller-scale or preparatory studies may be appropriate when they fit within the R01 scope and contribute to clarifying mechanisms or pathways relevant to HIV transmission/acquisition through reproductive health understanding.

What is the Funding Opportunity Number?

The Funding Opportunity Number is RFA-HD-12-198.

What CFDA number is associated with this opportunity?

This opportunity falls under CFDA 93.865 (Child Health and Human Development Extramural Research).

When was the opportunity posted?

The opportunity was posted on May 19, 2011.

What is the application deadline (closing date)?

The original and current closing date is August 11, 2011.

Is this funding opportunity still active?

No. The archive date is September 11, 2011, indicating the announcement has been archived.

How much total funding was estimated to be available?

The estimated total funding available was $2,000,000.

What is the award ceiling?

The award ceiling was $350,000.

Does the FOA anticipate making multiple awards?

Yes. With an estimated total funding level of $2,000,000 and an award ceiling of $350,000, the announcement indicates an expectation of multiple awards depending on application quality and budget structure.

Is this a discretionary grant program?

Yes. Administratively, it is a discretionary grant program using the NIH R01 funding mechanism.

What types of organizations are eligible to apply?

Eligibility is broad and includes many organization types across nonprofit, academic, governmental, and private sectors. Eligible applicants include nonprofits with or without 501(c)(3) status (including community-based and faith-based organizations), small businesses, for-profit organizations other than small businesses, public and private institutions of higher education, and a range of government entities.

Are community-based and faith-based organizations eligible?

Yes. The FOA includes nonprofits with or without 501(c)(3) status and explicitly notes community-based and faith-based organizations as eligible.

Are small businesses eligible?

Yes. Small businesses are listed as eligible applicants.

Are for-profit organizations eligible?

Yes. For-profit organizations other than small businesses are listed as eligible.

Are colleges and universities eligible?

Yes. Public and private institutions of higher education are eligible, including designated institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities (TCCUs).

Are government entities eligible to apply?

Yes. Eligible government entities include city or township governments, county governments, state governments, special district governments, and independent school districts. Eligible federal agencies are also included.

Are public housing authorities eligible?

Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.

Are tribal governments and tribal organizations eligible?

Yes. The FOA explicitly includes tribal governments (federally recognized) and other tribal organizations, and it also includes tribally controlled colleges and universities (TCCUs).

Are non-U.S. organizations allowed to apply?

Yes. The FOA allows non-U.S. entities (foreign organizations), as well as regional organizations, and U.S. territories or possessions.

Is cost sharing or matching required?

No. The FOA states there is no cost-sharing or matching requirement.

Where can applicants find the official announcement text and application details?

NICHD directs users to the NIH guide page for the announcement: http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-12-198.html.

Who should be contacted for technical issues accessing the notice?

Technical issues accessing the notice are routed to the NIH Office of Extramural Research (OER) webmaster contact listed in the announcement.

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