Opportunity Information: Apply for RFA HD 13 008

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Prevention of HIV Transmission/Acquisition through a better understanding of Reproductive Health (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Sep 11, 2012 and posted on Sep 11, 2012.
  • Applicants must submit their applications by Nov 29, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) County governments State governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education City or township governments Independent school districts Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) released this Research Project Grant (R01) opportunity to support studies that clarify how reproductive health and HIV prevention intersect, with the specific goal of improving our understanding of HIV acquisition and transmission. The core idea is that HIV risk and protection are tightly connected to reproductive biology and reproductive health behaviors, so the FOA encourages projects that look at these connections in a rigorous, integrated way. Rather than focusing on a single narrow factor, the announcement points investigators toward comprehensive approaches that combine behavioral and biomedical perspectives to generate new, practical insights for HIV prevention.

A key emphasis is on research that can explain mechanisms and pathways linking reproductive health to HIV outcomes. That might include how fertility intentions, pregnancy, contraception use, sexually transmitted infections, genital tract conditions, partner dynamics, or access to reproductive health services influence HIV susceptibility and transmission risk. The FOA is aimed at strengthening prevention science by supporting work that can identify modifiable targets, clarify why certain populations experience higher risk in reproductive contexts, and inform the design of smarter prevention strategies that fit real-world reproductive health needs. In other words, the focus is on understanding and prevention-relevant knowledge generation, not on developing new drugs.

This opportunity is not intended to pay for drug discovery efforts or large-scale clinical trials. Applicants are expected to propose R01-appropriate research projects, meaning hypothesis-driven or well-justified studies that can be accomplished within the scope and scale of a standard NIH research project grant. The announcement encourages multi-disciplinary designs, which often means bridging clinical or biological measures with behavioral data, healthcare delivery factors, and social or relationship contexts to capture how reproductive health realities shape HIV exposure, acquisition, and transmission.

Administratively, the funding instrument is a discretionary grant under an R01 mechanism, categorized under health-related assistance. The Funding Opportunity Number is RFA-HD-13-008, titled "Prevention of HIV Transmission/Acquisition through a better understanding of Reproductive Health (R01)." The FOA was posted and created on September 11, 2012, with an original and final application closing date of November 29, 2012, and an archive date of December 30, 2012. The estimated total funding amount listed is $2,000,000, indicating a limited pool intended to support a defined number of meritorious projects rather than an open-ended, ongoing program.

Eligibility is broad and spans many types of organizations. Eligible applicants include public and private institutions of higher education, nonprofit organizations with or without 501(c)(3) status (excluding higher education where specified), for-profit organizations (other than small businesses), small businesses, and a wide range of governmental entities such as state, county, city or township governments, special district governments, independent school districts, and public/Indian housing authorities. The FOA also explicitly includes organizations serving specific communities and regions, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. Importantly, non-U.S. entities are eligible: foreign organizations and foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed. There is no cost sharing or matching requirement.

The program is associated with multiple CFDA numbers that reflect its alignment with infectious disease and child health research portfolios, including 93.855 (Allergy and Infectious Diseases Research), 93.856 (Microbiology and Infectious Diseases Research), and 93.865 (Child Health and Human Development Extramural Research). For applicants seeking the full, official announcement details, the FOA was hosted through the NIH grants guide at the link provided in the source, and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contacts listed.

Frequently Asked Questions (FAQs)

What is the purpose of this NIH funding opportunity?

This Research Project Grant (R01) opportunity from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) supports research that clarifies how reproductive health and HIV prevention intersect, with the goal of improving understanding of HIV acquisition and transmission. The emphasis is on prevention-relevant knowledge generation through rigorous, integrated approaches.

What is the official Funding Opportunity Number and title?

The Funding Opportunity Number is RFA-HD-13-008. The title is "Prevention of HIV Transmission/Acquisition through a better understanding of Reproductive Health (R01)."

What NIH grant mechanism is being used?

The opportunity uses the NIH R01 Research Project Grant mechanism, which is intended for hypothesis-driven or well-justified research projects that fit within the typical scope and scale of an R01.

What kinds of research approaches does the FOA encourage?

The FOA encourages comprehensive, multidisciplinary approaches that combine behavioral and biomedical perspectives. Projects are expected to connect reproductive biology and reproductive health behaviors to HIV exposure, acquisition, and transmission in an integrated way.

What types of topics or factors are specifically highlighted as relevant to study?

Examples of relevant factors mentioned include fertility intentions, pregnancy, contraception use, sexually transmitted infections, genital tract conditions, partner dynamics, and access to reproductive health services, especially where these factors can help explain HIV susceptibility and transmission risk.

What is the central scientific emphasis of the FOA?

A key emphasis is on research that can explain mechanisms and pathways linking reproductive health to HIV outcomes. The aim is to strengthen prevention science by identifying modifiable targets, clarifying why certain populations experience higher risk in reproductive contexts, and informing smarter prevention strategies aligned with real-world reproductive health needs.

Is this opportunity intended to support drug discovery or new drug development?

No. The FOA states that the focus is on understanding and prevention-relevant knowledge generation, not on developing new drugs, and it is not intended to pay for drug discovery efforts.

Are large-scale clinical trials supported under this FOA?

No. The opportunity is not intended to fund large-scale clinical trials. Applicants are expected to propose research that is appropriate for the R01 mechanism.

What is the estimated total funding amount available?

The estimated total funding amount listed is $2,000,000, suggesting a limited funding pool intended to support a defined number of meritorious projects.

When was the FOA posted, and what are the key dates?

The FOA was posted and created on September 11, 2012. The original and final application closing date was November 29, 2012. The archive date was December 30, 2012.

Is this FOA still open for applications?

Based on the listed dates, the final application closing date was November 29, 2012, and the FOA was archived on December 30, 2012. That indicates it is not an active/open opportunity under those dates.

What type of award is this considered administratively?

Administratively, it is a discretionary grant under the R01 mechanism and is categorized as health-related assistance.

Who is eligible to apply?

Eligibility is broad and includes public and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status (excluding higher education where specified); for-profit organizations (other than small businesses); small businesses; and a wide range of governmental entities including state, county, city or township governments, special district governments, independent school districts, and public/Indian housing authorities.

Are community-based, faith-based, or minority-serving institutions included in eligibility?

Yes. The FOA explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

Can non-U.S. organizations apply?

Yes. The FOA states that foreign organizations and foreign institutions may apply. It also allows non-U.S. components of U.S. organizations and foreign components (as defined by NIH policy).

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

What CFDA numbers are associated with this opportunity?

The FOA is associated with multiple CFDA numbers: 93.855 (Allergy and Infectious Diseases Research), 93.856 (Microbiology and Infectious Diseases Research), and 93.865 (Child Health and Human Development Extramural Research).

Where can applicants find the official announcement details?

The full FOA was hosted through the NIH grants guide at the link provided in the source information for this opportunity.

Who is listed as a contact for technical access issues?

For technical access issues related to the FOA posting, the information directs users to the NIH Office of Extramural Research (OER) webmaster contacts listed in the announcement source.

What does "integrated" research mean in the context of this FOA?

In this FOA, integrated research refers to designs that bridge clinical or biological measures with behavioral data, healthcare delivery factors, and social or relationship contexts to capture how reproductive health realities shape HIV exposure, acquisition, and transmission.

What is this FOA not trying to do, in plain terms?

It is not meant to fund drug discovery or large clinical trials. It is meant to fund R01-scale studies that explain how reproductive health factors and behaviors connect to HIV prevention and transmission dynamics, generating practical insights for prevention science.

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