Opportunity Information: Apply for RFA HD 12 199

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Prevention of HIV Transmission/Acquisition through a better understanding of Reproductive Health (R03)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on May 19, 2011 and posted on May 19, 2011.
  • Applicants must submit their applications by Aug 11, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $750,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $50,000.00 in funding.
  • Eligible applicants include: For profit organizations other than small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Independent school districts County governments Small businesses Special district governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) released this Funding Opportunity Announcement as a Small Grant (R03) program focused on improving understanding of how reproductive health factors intersect with HIV prevention. The central aim is to support research that clarifies mechanisms and real-world conditions that influence HIV acquisition and transmission when viewed through a reproductive health lens, with the expectation that better knowledge in this area can generate new ideas and directions for HIV prevention. The FOA specifically encourages projects that integrate behavioral and biomedical perspectives, meaning proposals can look at biological susceptibility and transmission dynamics while also addressing behaviors, relationships, health care access, decision-making, and other contextual factors tied to reproductive health.

This opportunity is structured as an R03 small grant, which is typically used for early-stage, exploratory, or pilot work that can be completed with limited resources and within a shorter scope than larger NIH mechanisms. In practice, that usually means targeted studies that test feasibility, refine measurements, establish preliminary data, or explore under-studied questions that could later justify a larger R01 or clinical research program. NICHD emphasizes comprehensive behavioral-biomedical approaches, signaling interest in multidisciplinary projects that connect clinical or physiological aspects of reproductive health with prevention-relevant outcomes, rather than treating these domains as separate silos. At the same time, the announcement makes clear what it does not want to fund: it is not intended for drug discovery efforts or for large-scale clinical trials, so applications proposing extensive multi-site trials or development of new therapeutic compounds would be outside the intended scope.

Administratively, this is a discretionary grant opportunity with an activity category aligned to health, income security, and social services, and it is associated with CFDA 93.865 (Child Health and Human Development Extramural Research). The Funding Opportunity Number is RFA-HD-12-199, with a posted and creation date of May 19, 2011. The original and current closing date listed is August 11, 2011, and the opportunity was archived on September 11, 2011, indicating it was a time-limited call rather than an open-ended program announcement.

The funding parameters reflect the small-grant format. The estimated total funding available is $750,000, and the award ceiling is $50,000, with no cost sharing or matching requirement. That ceiling suggests NICHD expected compact, focused projects capable of producing meaningful, publishable insights or strong preliminary evidence without needing major infrastructure or trial-scale budgets.

Eligibility is broad and intentionally inclusive across many organizational types that can contribute to reproductive health and HIV prevention research. Eligible applicants include for-profit organizations (other than small businesses) and also small businesses; nonprofits with and without 501(c)(3) status; public and private institutions of higher education; local, county, and state governments; independent school districts; public housing authorities/Indian housing authorities; special district governments; Native American tribal governments (federally recognized) and tribal organizations (including those not federally recognized); and additional categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, U.S. territories or possessions, regional organizations, eligible federal agencies, and non-U.S. (foreign) entities. This breadth implies NICHD was aiming to attract proposals from academic research centers as well as community-connected organizations and diverse institutions that may have direct access to populations and settings where reproductive health and HIV prevention overlap.

For reference and full details, the FOA points applicants to the NIH grants guide page (http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-12-199.html). For technical issues accessing the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs)

What is this funding opportunity?

This is a Funding Opportunity Announcement (FOA) from the NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) for a Small Grant (R03) program focused on improving understanding of how reproductive health factors intersect with HIV prevention.

What is the main purpose of the FOA?

The central aim is to support research that clarifies mechanisms and real-world conditions that influence HIV acquisition and transmission when examined through a reproductive health lens. The expectation is that improved knowledge in this area will generate new ideas and directions for HIV prevention.

What kinds of research approaches does NICHD encourage under this FOA?

The FOA specifically encourages projects that integrate behavioral and biomedical perspectives. This means proposals may address biological susceptibility and transmission dynamics while also considering behaviors, relationships, health care access, decision-making, and other contextual factors tied to reproductive health.

What does "behavioral-biomedical" integration mean in this context?

It means the project connects clinical or physiological aspects of reproductive health with prevention-relevant outcomes, rather than treating biological and behavioral dimensions as separate topics. The FOA signals interest in comprehensive, multidisciplinary approaches that link these domains.

What is an NIH R03 Small Grant, and why does it matter for project scope?

An R03 is typically used for early-stage, exploratory, or pilot work that can be completed with limited resources and within a shorter scope than larger NIH mechanisms. In practice, this often includes targeted studies that test feasibility, refine measurements, establish preliminary data, or explore under-studied questions that could later support a larger R01 or clinical research program.

Is this FOA intended for large-scale clinical trials?

No. The announcement indicates it is not intended for large-scale clinical trials, including extensive multi-site trials.

Is drug discovery research supported under this FOA?

No. The FOA states it is not intended for drug discovery efforts, including the development of new therapeutic compounds.

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number is RFA-HD-12-199.

Which NIH Institute released this FOA?

The FOA was released by the NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

What is the CFDA number associated with this opportunity?

The opportunity is associated with CFDA 93.865, titled Child Health and Human Development Extramural Research.

How much total funding was estimated to be available?

The estimated total funding available is $750,000.

What is the maximum award amount (award ceiling)?

The award ceiling listed is $50,000.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

What is the activity category associated with this grant?

It is described as a discretionary grant opportunity with an activity category aligned to health, income security, and social services.

When was this FOA posted?

The posted (and creation) date is May 19, 2011.

What was the application closing date?

The original and current closing date listed is August 11, 2011.

Is this opportunity still open?

No. The opportunity was archived on September 11, 2011, indicating it was a time-limited call and is no longer accepting applications.

Who is eligible to apply?

Eligibility is broad and includes many organization types, including: for-profit organizations (other than small businesses) and small businesses; nonprofits with and without 501(c)(3) status; public and private institutions of higher education; local, county, and state governments; independent school districts; public housing authorities/Indian housing authorities; special district governments; Native American tribal governments (federally recognized) and tribal organizations (including those not federally recognized); Alaska Native and Native Hawaiian Serving Institutions; Hispanic-serving institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; U.S. territories or possessions; regional organizations; eligible federal agencies; and non-U.S. (foreign) entities.

Are non-U.S. (foreign) organizations eligible?

Yes. The eligibility list explicitly includes non-U.S. (foreign) entities.

Are tribal governments and tribal organizations eligible?

Yes. Eligible applicants include Native American tribal governments (federally recognized) as well as tribal organizations, including those not federally recognized.

Can community-based or faith-based organizations apply?

Yes. The eligibility list includes faith-based or community-based organizations.

Where can applicants find the full FOA text and details?

The FOA points to the NIH grants guide page at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-12-199.html

Who should be contacted for technical issues accessing the announcement?

For technical issues accessing the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

What general types of outcomes is NICHD expecting from projects funded under this R03?

Based on the R03 small-grant format described, NICHD is aiming for compact, focused projects that can produce meaningful, publishable insights or strong preliminary evidence, such as feasibility results, refined measures, preliminary data, or explored under-studied questions that could inform future HIV prevention research directions.

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