Opportunity Information: Apply for CDC RFA GH11 11090501SUPP16

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Program Expansion Supplement: Strengthening Local Capacity to Provide Sustainable HIV-Related Care and Treatment Services in South Africa" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Aug 02, 2016.
  • Applicants must submit their applications by Oct 01, 2016 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $15,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for CDC RFA GH11 11090501SUPP16

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Opportunity Summary:

The "Program Expansion Supplement: Strengthening Local Capacity to Provide Sustainable HIV-Related Care and Treatment Services in South Africa" is a CDC cooperative agreement funding opportunity under PEPFAR that is meant to deepen and extend U.S. technical support for South Africa's national HIV response. It sits within the broader PEPFAR model where CDC, working under the U.S. Global AIDS Coordinator, partners with host-country governments to tailor support to national strategies and to strengthen systems that can maintain results long after external funding declines. The overall thrust is not just delivering services, but improving how services are planned, managed, measured, and sustained across community, primary care, and tertiary levels of the health system.

Programmatically, the opportunity emphasizes a full continuum of HIV work. On prevention, it highlights expanding confidential HIV counseling and testing that is actively linked to evidence-based behavior change interventions, alongside efforts to reduce mother-to-child transmission. On treatment and clinical care, it prioritizes improving management of HIV/AIDS, sexually transmitted infections, and opportunistic infections, while also strengthening laboratory diagnostic capacity that supports diagnosis, monitoring, and treatment decisions. It also explicitly calls out the integration of tuberculosis services, reflecting the high burden of HIV/TB co-infection, and supports the initiation and expansion of antiretroviral therapy services. In parallel, the FOA underscores surveillance and data use as core capacities: expanding HIV/STI/TB surveillance, improving laboratory support for surveillance and blood safety screening, and building national and subnational capacity to use data for program management and performance improvement. It also encourages the development, validation, and evaluation of public health programs so that interventions are better targeted and continuously improved based on evidence.

A major theme running through the announcement is coordination and efficiency, aligned with Global Health Initiative principles. Recipients may be asked to participate in efforts that raise impact through integration and partner alignment, including strategic coordination across implementers and with government, stronger engagement with multilateral organizations and public-private partnerships, and steps that reinforce country ownership. The FOA also signals cross-cutting expectations such as taking a woman- and girl-centered approach, investing in health systems to build sustainability, improving metrics and monitoring and evaluation, and promoting innovation and applied learning that can refine service delivery models over time.

In terms of purpose and outcomes, the FOA frames success around PEPFAR's overarching goals in South Africa: reducing HIV- and TB-related morbidity and mortality, preventing new infections, and strengthening the effectiveness of the HIV response system at district, provincial, and national levels. A practical, on-the-ground expectation is that the funded partner will work closely with district Departments of Health and their designees to identify gaps, shape policies and programs, and improve the district-level response for HIV prevention, care, and treatment. This focus on district systems reflects the idea that durable gains depend on how well local management, supervision, and clinical quality function where patients actually receive care.

Operationally, this supplement builds on earlier CDC/PEPFAR investments in HIV clinical services and ART programs, and it is designed to ensure continuity of technical assistance to the South African National Department of Health as services expand to both current and future clients. The FOA specifically indicates funding to Health Systems Trust to continue and expand technical assistance supporting comprehensive HIV prevention, care, and ART scale-up. Key activities described include building the capacity of health personnel through continuous quality improvement approaches, setting and reinforcing standards of care, providing mentorship and training for clinical and ancillary staff, and ensuring day-to-day adherence to South Africa's National Care and Treatment guidelines. The recipient is expected to operate under the direction of provincial and district health authorities and coordinate with the U.S. Government-designated district coordination partner, reinforcing a managed, government-led implementation structure rather than a parallel system.

Geographically, the work may be concentrated in CDC priority districts, with potential district coordination responsibilities in one or more provinces listed in the announcement: Free State, Eastern Cape, KwaZulu-Natal, and North West. This suggests the supplement is meant to intensify support where the epidemic burden is high or where system strengthening can yield outsized improvements in coverage and quality.

From an administrative standpoint, the opportunity is a discretionary cooperative agreement (CFDA 93.067) issued by the HHS Centers for Disease Control and Prevention (CGH). The funding opportunity number is CDC RFA GH11 11090501SUPP16, originally posted August 2, 2016, with an original application deadline of October 1, 2016 (11:59 p.m. ET for electronic submissions). The ceiling listed is $15,000,000, with an expectation of a single award, which matches the narrative indicating targeted continued support through a specific technical partner.

Frequently Asked Questions (FAQs)

What is the name of this grant opportunity?

The opportunity is titled "Program Expansion Supplement: Strengthening Local Capacity to Provide Sustainable HIV-Related Care and Treatment Services in South Africa."

Which U.S. agency is offering this opportunity?

This is a discretionary cooperative agreement issued by the HHS Centers for Disease Control and Prevention (CDC), specifically within CDC's Center for Global Health (CGH).

Is this opportunity part of PEPFAR?

Yes. The announcement describes it as a CDC cooperative agreement funding opportunity under PEPFAR, aligned with the broader PEPFAR model of supporting host-country national strategies and long-term sustainability.

What is the main purpose of this supplement?

The purpose is to deepen and extend U.S. technical support for South Africa's national HIV response, with an emphasis on strengthening local systems so results can be maintained as external funding declines.

Is the focus on direct service delivery or systems strengthening?

While the work spans the HIV continuum, the overall thrust is not only delivering services, but improving how services are planned, managed, measured, coordinated, and sustained across community, primary care, and tertiary levels.

What outcomes does the FOA define as success?

The FOA frames success around PEPFAR's overarching goals in South Africa: reducing HIV- and TB-related morbidity and mortality, preventing new infections, and strengthening the effectiveness of the HIV response system at district, provincial, and national levels.

What prevention activities are emphasized?

The prevention emphasis includes expanding confidential HIV counseling and testing that is actively linked to evidence-based behavior change interventions, along with efforts to reduce mother-to-child transmission.

What treatment and clinical care areas are prioritized?

The FOA prioritizes improving management of HIV/AIDS, sexually transmitted infections (STIs), and opportunistic infections, and it supports initiation and expansion of antiretroviral therapy (ART) services.

How does the opportunity address tuberculosis (TB)?

It explicitly calls for integration of tuberculosis services, reflecting the high burden of HIV/TB co-infection, and positions TB integration as part of strengthening the continuum of care.

What laboratory-related work is included?

The opportunity includes strengthening laboratory diagnostic capacity to support diagnosis, monitoring, and treatment decisions, as well as improving laboratory support for surveillance and blood safety screening.

What does the FOA say about surveillance and data use?

Surveillance and data use are described as core capacities. The FOA highlights expanding HIV/STI/TB surveillance and building national and subnational capacity to use data for program management and performance improvement.

Does the announcement include monitoring and evaluation expectations?

Yes. It signals cross-cutting expectations around improving metrics and monitoring and evaluation, along with using data for performance improvement.

Are program development and evaluation part of the work?

Yes. The FOA encourages the development, validation, and evaluation of public health programs so interventions can be better targeted and continuously improved based on evidence.

What does the FOA say about coordination and partner alignment?

Coordination and efficiency are major themes, aligned with Global Health Initiative principles. Recipients may be asked to participate in efforts that increase impact through integration, strategic coordination across implementers and government, engagement with multilateral organizations and public-private partnerships, and reinforcement of country ownership.

What cross-cutting approaches are highlighted?

The FOA highlights a woman- and girl-centered approach, investment in health systems for sustainability, stronger metrics and monitoring and evaluation, and promoting innovation and applied learning to refine service delivery models over time.

What is expected at the district level?

A practical expectation is that the funded partner will work closely with district Departments of Health and their designees to identify gaps, shape policies and programs, and improve the district-level response for HIV prevention, care, and treatment.

How does this supplement relate to prior CDC/PEPFAR investments?

The supplement builds on earlier CDC/PEPFAR investments in HIV clinical services and ART programs and is designed to ensure continuity of technical assistance to South Africa's National Department of Health as services expand to current and future clients.

Which organization is indicated to receive funding in the announcement narrative?

The FOA specifically indicates funding to Health Systems Trust to continue and expand technical assistance supporting comprehensive HIV prevention, care, and ART scale-up.

What types of capacity-building activities are described?

Key activities include building the capacity of health personnel through continuous quality improvement approaches, setting and reinforcing standards of care, providing mentorship and training for clinical and ancillary staff, and supporting day-to-day adherence to South Africa's National Care and Treatment guidelines.

Who directs or oversees the recipient's work on the ground?

The recipient is expected to operate under the direction of provincial and district health authorities and coordinate with the U.S. Government-designated district coordination partner, reflecting a government-led implementation structure.

Where in South Africa may the work be concentrated?

The work may be concentrated in CDC priority districts, with potential district coordination responsibilities in one or more of the provinces listed in the announcement: Free State, Eastern Cape, KwaZulu-Natal, and North West.

What is the assistance mechanism type?

The opportunity is a discretionary cooperative agreement.

What is the CFDA number for this opportunity?

The CFDA number listed is 93.067.

What is the funding opportunity number?

The funding opportunity number is CDC RFA GH11 11090501SUPP16.

When was the opportunity originally posted?

The announcement states it was originally posted on August 2, 2016.

What was the original application deadline?

The original application deadline was October 1, 2016, with electronic submissions due by 11:59 p.m. ET.

What is the maximum funding amount (ceiling) listed?

The ceiling listed in the announcement is $15,000,000.

How many awards does the FOA expect to make?

The FOA indicates an expectation of a single award, consistent with the narrative describing targeted continued support through a specific technical partner.

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