Opportunity Information: Apply for CDC RFA GH11 11100501SUPP16
Apply for CDC RFA GH11 11100501SUPP16
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Program Expansion Supplement: Supporting Health Worker Staffing in South Africa under PEPFAR" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Aug 02, 2016.
- Applicants must submit their applications by Oct 01, 2016 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,360,545.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
Program Expansion Supplement: Supporting Health Worker Staffing in South Africa under PEPFAR is a discretionary U.S. government funding opportunity from the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), issued under a cooperative agreement mechanism. The opportunity is framed as a program expansion supplement and is tied to PEPFAR priorities in South Africa, with a focus on strengthening health worker staffing to support delivery and scale-up of voluntary medical male circumcision (VMMC) services as a core HIV prevention intervention. The funding opportunity number is CDC RFA GH11 11100501SUPP16, listed under CFDA 93.067 (Health). It was created on August 2, 2016, with an application deadline of October 1, 2016 (electronically submitted by 11:59 p.m. ET). The announcement anticipated one award, with an award ceiling of $1,360,545. Eligibility is listed broadly as “Others,” with clarification to be provided in the opportunity’s additional eligibility text.
The public health rationale for the supplement is grounded in strong evidence that VMMC is a one-time procedure that provides long-term protection by reducing a man’s risk of acquiring HIV through heterosexual exposure for life. The announcement highlights that three randomized controlled trials found roughly a 60% reduction in HIV acquisition risk among circumcised men, placing VMMC among the most effective HIV prevention approaches currently available. It also notes extended follow-up data from the Uganda and Kenya trials showing that protection was sustained over time and in some analyses increased, with reported effectiveness ranges of approximately 67% to 73% in one setting and around 58% in another during longer post-trial follow-up periods. This evidence base is positioned as the scientific foundation for continued investment in VMMC programming under PEPFAR.
The opportunity situates South Africa’s work within broader global guidance and targets established by WHO and UNAIDS. In March 2007, WHO/UNAIDS issued normative guidance recognizing VMMC as an additional important intervention for reducing male heterosexually acquired HIV infection. That same global policy push was reinforced through the Joint Strategic Action Framework designed to accelerate VMMC scale-up across eastern and southern African countries with generalized epidemics and historically low male circumcision prevalence. The referenced regional target aimed for 80% circumcision coverage among males aged 15 to 49 in 14 priority countries, representing about 20.3 million VMMCs by the end of 2016. While the grant text does not lay out South Africa-specific numeric targets in the excerpt, it clearly ties the supplement’s intent to expanding capacity so the country can contribute meaningfully to these scale-up goals.
A central part of the justification is the projected population-level impact and economic value of rapid VMMC expansion. Mathematical modeling cited in the announcement suggests that if 80% of adult men become circumcised within five years, roughly 3.4 million new HIV infections could be prevented over 15 years, alongside potential savings of up to $16.5 billion in HIV care and treatment costs. For South Africa specifically, the modeling claim presented is particularly concrete: under that rapid scale-up scenario, one HIV infection could be prevented for every five men circumcised. These projections are used to argue that short-term investments in staffing and service delivery can translate into substantial long-term reductions in HIV incidence and future treatment expenditures.
Beyond the direct protective effect for men, the opportunity emphasizes VMMC as a service delivery platform that can bring men into the health system for broader prevention and linkage services. The announcement notes that VMMC programs offer opportunities for health education and counseling, particularly HIV testing and counseling, which is recommended and provided across PEPFAR VMMC programming. It also underscores the linkage-to-care function: men who test HIV-positive through VMMC-related services are referred for HIV care and treatment. This matters not only for the individual’s health outcomes but also because effective antiretroviral treatment reduces the likelihood of onward transmission to sexual partners, expanding the community-level prevention impact of VMMC programs.
The grant description also highlights indirect but meaningful benefits for women. As VMMC reduces HIV prevalence among men over time, women’s risk declines because they are less likely to encounter HIV-infected partners. The announcement states that in a rapid scale-up scenario, nearly half of the infections prevented could be among women, which reinforces the argument that VMMC is not solely a male-focused intervention in terms of public health impact. It further notes potential reductions in other sexually transmitted infections for women with circumcised partners, including lower risk of infection with carcinogenic strains of HPV and associated reductions in cervical cancer risk, framing VMMC as a broader sexual and reproductive health intervention with downstream benefits.
In practical terms, the “supporting health worker staffing” emphasis signals that the supplement is meant to bolster the human resources needed to deliver VMMC safely, efficiently, and at sufficient scale within South Africa’s PEPFAR-supported programs. While the excerpt does not enumerate specific staffing models or cadres, the overall thrust is clear: expanding or sustaining the workforce capacity behind VMMC service delivery is viewed as essential to reaching coverage targets, maintaining service quality, integrating HIV testing and counseling, ensuring referral and linkage pathways, and ultimately achieving the modeled reductions in HIV transmission and long-term cost savings.
Frequently Asked Questions (FAQs)
What is the name of this funding opportunity?
The opportunity is titled "Program Expansion Supplement: Supporting Health Worker Staffing in South Africa under PEPFAR."
Which U.S. government agency is offering this grant?
This is a U.S. Department of Health and Human Services (HHS) funding opportunity issued by the Centers for Disease Control and Prevention (CDC).
Is this a grant or a cooperative agreement?
The announcement is issued under a cooperative agreement mechanism (a form of federal assistance that typically involves substantial involvement by the federal agency compared with a standard grant).
What is the main purpose of this program expansion supplement?
The supplement is intended to strengthen health worker staffing in South Africa to support the delivery and scale-up of voluntary medical male circumcision (VMMC) services under PEPFAR, as a core HIV prevention intervention.
What does VMMC stand for, and why is it emphasized in this opportunity?
VMMC stands for voluntary medical male circumcision. It is emphasized because the opportunity describes VMMC as a highly effective HIV prevention approach supported by strong scientific evidence, and because expanding staffing capacity is viewed as essential to scaling VMMC services safely and efficiently.
What evidence does the announcement cite for VMMC effectiveness in preventing HIV?
The announcement references three randomized controlled trials that found roughly a 60% reduction in HIV acquisition risk among circumcised men (for heterosexual exposure). It also cites extended follow-up data from Uganda and Kenya indicating protection was sustained over time and, in some analyses, increased, with effectiveness reported in ranges of approximately 67% to 73% in one setting and around 58% in another during longer post-trial follow-up periods.
Is VMMC described as a one-time or recurring intervention?
The announcement describes VMMC as a one-time procedure that provides long-term protection by reducing a man's risk of acquiring HIV through heterosexual exposure for life.
How does this opportunity align with PEPFAR priorities in South Africa?
The opportunity is framed as being tied to PEPFAR priorities in South Africa, with a specific focus on strengthening staffing to support VMMC service delivery and scale-up as part of HIV prevention programming.
How does this opportunity relate to WHO/UNAIDS guidance?
The announcement situates VMMC scale-up within global guidance and targets, noting that WHO and UNAIDS issued normative guidance in March 2007 recognizing VMMC as an additional important intervention for reducing male heterosexually acquired HIV infection.
What regional or global VMMC scale-up target is referenced?
The announcement references a target of 80% circumcision coverage among males aged 15 to 49 in 14 priority countries, representing about 20.3 million VMMCs by the end of 2016, as part of efforts to accelerate VMMC scale-up in eastern and southern Africa.
Does the excerpt list specific numeric VMMC targets for South Africa?
No. The excerpt does not provide South Africa-specific numeric targets, but it clearly connects the supplement to expanding capacity so South Africa can contribute meaningfully to broader scale-up goals.
What population-level impact does the announcement claim could result from rapid VMMC expansion?
The announcement cites mathematical modeling suggesting that if 80% of adult men become circumcised within five years, roughly 3.4 million new HIV infections could be prevented over 15 years.
What cost savings are mentioned in relation to VMMC scale-up?
The announcement cites modeling that projects potential savings of up to $16.5 billion in HIV care and treatment costs under rapid scale-up assumptions.
What specific modeling claim is provided for South Africa?
For South Africa, the announcement presents a concrete modeling claim that under a rapid scale-up scenario, one HIV infection could be prevented for every five men circumcised.
Besides HIV prevention, what other service benefits are connected to VMMC programs in the announcement?
The announcement describes VMMC as a platform for bringing men into the health system for broader prevention and linkage services. It highlights health education and counseling, including HIV testing and counseling, and notes that men who test HIV-positive are referred for HIV care and treatment.
How does HIV treatment linkage relate to prevention, according to the announcement?
The announcement notes that effective antiretroviral treatment reduces the likelihood of onward transmission to sexual partners, which expands the community-level prevention impact beyond the direct protective effect of VMMC for men.
Does the announcement describe benefits of VMMC for women?
Yes. It states that as HIV prevalence among men declines over time, women's risk declines because they are less likely to encounter HIV-infected partners. It also notes that nearly half of infections prevented in a rapid scale-up scenario could be among women.
Are any non-HIV health benefits mentioned for women?
Yes. The announcement notes potential reductions in other sexually transmitted infections for women with circumcised partners, including lower risk of infection with carcinogenic strains of HPV and associated reductions in cervical cancer risk.
What is the funding opportunity number?
The funding opportunity number is CDC RFA GH11 11100501SUPP16.
What CFDA program is this opportunity listed under?
It is listed under CFDA 93.067 (Health).
When was this funding opportunity created?
The opportunity was created on August 2, 2016.
What was the application deadline?
The application deadline was October 1, 2016, with electronic submission due by 11:59 p.m. Eastern Time (ET).
How many awards did the announcement anticipate making?
The announcement anticipated one award.
What is the award ceiling listed in the announcement?
The award ceiling is $1,360,545.
Who is eligible to apply based on the excerpt?
Eligibility is listed broadly as "Others," with the excerpt noting that clarification would be provided in the opportunity's additional eligibility text.
Does the excerpt specify which types of health worker roles or staffing models will be funded?
No. The excerpt does not enumerate specific staffing models or cadres. It emphasizes that expanding or sustaining workforce capacity behind VMMC service delivery is essential for scale-up, service quality, integration of HIV testing and counseling, and referral and linkage pathways.
What practical outcomes is staffing support meant to enable?
Based on the excerpt, staffing support is positioned to help deliver VMMC safely and efficiently at sufficient scale, maintain service quality, integrate HIV testing and counseling, ensure referral and linkage to care for those who test HIV-positive, and contribute to reductions in HIV transmission and long-term cost savings described in modeling.
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