Opportunity Information: Apply for CDC RFA GH15 15480201SUPP16
Apply for CDC RFA GH15 15480201SUPP16
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Program Expansion Supplement: Supporting HIV and Tuberculosis Response in the Kingdom of Lesotho through District-based Comprehensive Prevention, Care and Treatment Program and Health Systems Strengthening under PEPFAR" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Jul 29, 2016.
- Applicants must submit their applications by Sep 27, 2016 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $388,800.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
This grant opportunity is a CDC cooperative agreement under PEPFAR designed to expand and strengthen HIV services and TB/HIV collaborative activities in the Kingdom of Lesotho using a district-based delivery model. The central idea is that district health management teams sit at the right level of the health system to coordinate real, day-to-day improvements across facilities and communities. Instead of running HIV and TB services as scattered projects, the program emphasizes coordinated district ownership, tighter management, and practical service-delivery improvements that can be sustained and replicated beyond the life of the award.
The program focuses on supporting the full continuum of HIV prevention, care, and treatment, with CDC backing activities that move patients smoothly from initial diagnosis to long-term viral suppression. That continuum includes strengthening HIV testing and counseling to identify people living with HIV who are not yet diagnosed, ensuring rapid linkage and enrollment into HIV care once someone tests positive, completing clinical staging and starting antiretroviral therapy (ART), and then maintaining retention and adherence so patients stay in care and achieve viral suppression. The expectation is not just more services, but better performance across each step of the cascade so fewer people are lost between testing, treatment initiation, and long-term follow-up.
A key requirement is that activities serve both adults and children, with deliberate attention to groups with higher risk or greater vulnerability. The priority populations called out include pregnant women (reflecting the need to prevent mother-to-child transmission and keep mothers healthy), people co-infected with TB and HIV (where integrated care is essential), adolescents (who often face unique barriers to testing and retention), and children under five (who need timely diagnosis and pediatric treatment pathways). Strengthening TB/HIV collaboration is woven into the design, recognizing that TB remains a major cause of illness and death among people with HIV and that effective programming depends on integrated screening, referral, and treatment services.
The opportunity also stresses building strong two-way linkages between facilities and communities so care does not end at the clinic door. Applicants are expected to create and strengthen bidirectional connections between health facilities and community-based programs such as outreach initiatives, village health worker programs, and services for orphans and vulnerable children (OVC). In practice, this means improving referral and follow-up systems, supporting community tracking for missed appointments, helping patients navigate services, and ensuring that community programs feed back into clinic care in a structured way. The goal is a more continuous patient experience, where community support reinforces clinical outcomes and clinics actively coordinate with community platforms.
The primary project goal is to develop and implement effective, replicable, and sustainable district-level models that measurably increase a district's capacity to deliver HIV/TB prevention, care, and treatment. Success is framed around three linked outcomes: finding undiagnosed HIV infections, strengthening linkage into care and treatment, and improving clinical results for people living with HIV across the continuum, culminating in viral suppression. Beyond the main cascade, the award also supports additional operational and service delivery components considered critical to comprehensive HIV care, reflecting the reality that outcomes depend on management systems, consistent practices, and reliable service quality, not just clinical protocols.
This announcement is positioned as a follow-on to CDC's earlier funding opportunity PS09-930, with revisions shaped by recommendations from USG PEPFAR technical working groups, the PEPFAR Lesotho team, local partners, and the Lesotho Ministry of Health. Those revisions were aimed at accelerating HIV and TB/HIV care and treatment through more integrated clinical services. The program aligns with a broader PEPFAR shift in Lesotho to a district-based approach that typically designates only one USG care and treatment implementing partner per district to reduce fragmentation and improve accountability.
Geographically, CDC-supported clinical services under this model cover four districts: Leribe, Berea, Quthing, and Qacha's Nek. The grant builds on Lesotho's antiretroviral program experience since national ARV implementation began in 2002, using lessons learned to institutionalize routine, consistent systems that improve efficiency in district management and service delivery. The emphasis on institutionalization is important: the program is not only trying to deliver activities during the award period, but also to embed practices and management routines that continue to improve HIV and TB outcomes over time.
Administratively, this is a discretionary funding opportunity offered by the US Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), Center for Global Health, structured as a cooperative agreement (meaning CDC is expected to have substantial involvement compared to a standard grant). The opportunity number is CDC RFA GH15 15480201SUPP16, under CFDA 93.067. It anticipated a single award, with an award ceiling of $388,800. The original posting date was July 29, 2016, and the original application deadline was September 27, 2016 (with electronic submissions due by 11:59 p.m. Eastern Time). Eligibility is listed broadly as "Others," with further details indicated in the opportunity's eligibility clarification text.
Frequently Asked Questions (FAQs)
What is this funding opportunity?
This is a CDC discretionary cooperative agreement under PEPFAR focused on expanding and strengthening HIV services and TB/HIV collaborative activities in the Kingdom of Lesotho using a district-based delivery model.
What is the main idea behind the district-based delivery model?
The program is built around the idea that district health management teams are positioned to coordinate practical, day-to-day improvements across facilities and communities. Instead of running HIV and TB services as scattered projects, the approach emphasizes coordinated district ownership, tighter management, and service-delivery improvements that can be sustained and replicated beyond the award period.
What is the overall purpose of the program?
The primary project goal is to develop and implement effective, replicable, and sustainable district-level models that measurably increase a district's capacity to deliver HIV/TB prevention, care, and treatment.
What outcomes define success under this opportunity?
Success is framed around three linked outcomes: (1) finding undiagnosed HIV infections, (2) strengthening linkage into care and treatment, and (3) improving clinical results across the continuum of care, culminating in viral suppression.
Which parts of the HIV care continuum are emphasized?
The opportunity emphasizes strengthening the full continuum of HIV prevention, care, and treatment, including: HIV testing and counseling to identify people not yet diagnosed; rapid linkage and enrollment into HIV care after a positive test; clinical staging and initiation of antiretroviral therapy (ART); and retention and adherence support so patients stay in care and achieve viral suppression.
Is the expectation to increase service volume or improve performance?
The expectation is not only to provide more services, but to improve performance across each step of the HIV cascade so fewer people are lost between testing, treatment initiation, and long-term follow-up.
How does TB/HIV collaboration fit into the program design?
Strengthening TB/HIV collaboration is woven into the design. The opportunity recognizes TB as a major cause of illness and death among people with HIV and emphasizes integrated screening, referral, and treatment services.
Which populations must be served?
Activities are required to serve both adults and children, with deliberate attention to groups with higher risk or greater vulnerability.
Which priority populations are specifically highlighted?
The priority populations called out include pregnant women, people co-infected with TB and HIV, adolescents, and children under five.
Why are pregnant women a priority population in this opportunity?
Pregnant women are prioritized to support prevention of mother-to-child transmission and to keep mothers healthy through effective HIV services.
Why is there a special focus on adolescents?
The opportunity notes that adolescents often face unique barriers to HIV testing and retention in care, so programming should deliberately address their needs.
Why are children under five specifically mentioned?
Children under five are highlighted because they need timely diagnosis and pediatric treatment pathways, which require deliberate attention within district service models.
What does the opportunity require regarding facility and community linkages?
Applicants are expected to create and strengthen bidirectional (two-way) linkages between health facilities and community-based programs so care does not stop at the clinic door.
What types of community-based programs are referenced?
The opportunity references outreach initiatives, village health worker programs, and services for orphans and vulnerable children (OVC) as examples of community platforms to link with facilities.
What does “bidirectional†linkage mean in practice?
In practice, bidirectional linkages mean improving referral and follow-up systems, supporting community tracking for missed appointments, helping patients navigate services, and ensuring community programs feed structured information back into clinic care.
What is meant by “district ownership†and “reduced fragmentation�
The program emphasizes coordinated district ownership and management to avoid HIV/TB services operating as separate, scattered projects. It aligns with a broader PEPFAR shift in Lesotho toward a district-based approach that typically designates only one USG care and treatment implementing partner per district to reduce fragmentation and improve accountability.
Which districts are covered for CDC-supported clinical services under this model?
CDC-supported clinical services under the district-based model cover four districts: Leribe, Berea, Quthing, and Qacha's Nek.
How does this opportunity relate to previous CDC funding in Lesotho?
This announcement is positioned as a follow-on to CDC's earlier funding opportunity PS09-930, with revisions informed by recommendations from USG PEPFAR technical working groups, the PEPFAR Lesotho team, local partners, and the Lesotho Ministry of Health.
What were the revisions intended to accomplish?
The revisions were aimed at accelerating HIV and TB/HIV care and treatment through more integrated clinical services, consistent with the shift to a district-based approach.
What does “institutionalization†mean in the context of this program?
Institutionalization refers to embedding routine, consistent practices and management systems in district service delivery so improvements continue over time, not just during the award period.
What kind of award mechanism is this?
This opportunity is structured as a cooperative agreement, meaning CDC is expected to have substantial involvement compared to a standard grant.
Which federal agency and CDC unit are associated with this funding?
The opportunity is offered by the US Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), Center for Global Health.
What is the opportunity number and CFDA listing?
The opportunity number is CDC RFA GH15 15480201SUPP16, under CFDA 93.067.
How many awards were anticipated?
The opportunity anticipated a single award.
What is the award ceiling?
The award ceiling is $388,800.
When was the opportunity originally posted?
The original posting date was July 29, 2016.
What was the original application deadline and time zone?
The original application deadline was September 27, 2016, with electronic submissions due by 11:59 p.m. Eastern Time.
Who is eligible to apply?
Eligibility is listed broadly as “Others,†with additional details indicated in the opportunity's eligibility clarification text.
Is the program limited to HIV services, or does it include TB-related activities too?
It includes both HIV services and TB/HIV collaborative activities, with an emphasis on integrated approaches for people affected by both conditions.
Does the opportunity support activities beyond direct clinical services?
Yes. In addition to the main HIV cascade focus, the award supports additional operational and service delivery components considered critical to comprehensive HIV care, recognizing that outcomes depend on management systems, consistent practices, and reliable service quality.
What is the expected “end point†of the HIV service continuum in this program?
The continuum is expected to lead to long-term viral suppression, supported by retention and adherence strategies and coordinated facility-community follow-up.
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