Opportunity Information: Apply for CDC RFA GH13 13660302SUPP16

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Program Expansion Supplement: Supporting Laboratory Strengthening Activities in Resource-Limited Countries under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Aug 23, 2016.
  • Applicants must submit their applications by Oct 22, 2016 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for CDC RFA GH13 13660302SUPP16

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Opportunity Summary:

This funding opportunity is a CDC cooperative agreement supplement under PEPFAR aimed at expanding and strengthening laboratory systems in resource-limited countries as a practical way to improve HIV/AIDS prevention, treatment, and care outcomes. It sits within PEPFARs broader mandate to deliver immediate, comprehensive, evidence-based action against the global HIV epidemic and to build durable local capacity. The program is framed around the major PEPFAR targets from the reauthorization era (often summarized as 3,12,12): treating millions of people with antiretroviral therapy, providing care to millions affected by HIV (including orphans and vulnerable children), and preventing millions of new infections. A key enabling goal tied to these targets is workforce development, including large-scale training of new health care workers, with laboratories treated as a foundational part of a functioning health system rather than a stand-alone technical project.

The core purpose of the award is public health program improvement rather than research. Funds are intended to support activities that prevent or control disease and improve health services, especially through stronger diagnostic and laboratory capacity. Research is explicitly not allowed under this mechanism, although certain non-research activities that can resemble research operationally may be supported when they are used for program implementation and improvement. Examples mentioned in the opportunity include formative assessments, surveys, routine disease surveillance, program monitoring and evaluation, and field evaluation of diagnostic tests. In other words, the emphasis is on applied, real-world work that strengthens service delivery and decision-making, even if institutional processes (like human subjects review) are sometimes triggered by the nature of data collection.

PEPFAR implementation in this announcement is described as country-tailored and aligned with national strategies. Under the leadership of the U.S. Global AIDS Coordinator, CDC works with host governments and partners to assess country needs and design customized assistance that fits within each countrys strategic plan and partnership framework. CDC typically concentrates on a small number of major program areas per country to improve focus and effectiveness. Within that approach, laboratory strengthening is positioned as a cross-cutting requirement that supports clinical care, surveillance, treatment monitoring, and broader public health policy.

Program priorities highlighted in the opportunity reflect the full HIV service continuum and the related infections that commonly drive illness and death among people living with HIV. On prevention, the announcement points to scaling confidential counseling and testing linked to evidence-based behavior change and strengthening programs to reduce mother-to-child transmission. On care and treatment, it emphasizes improving management of sexually transmitted infections, enhancing laboratory diagnostic capacity, and strengthening the diagnosis and treatment of opportunistic infections. It also calls out tuberculosis specifically as a major intercurrent disease affecting HIV-infected patients, alongside the broader rollout and support of antiretroviral therapy services. A third priority area is surveillance and national program management: expanding HIV/STI/TB surveillance and strengthening laboratory support for surveillance, diagnosis, treatment monitoring, and blood safety screening. Finally, the opportunity acknowledges the value of developing, validating, and evaluating public health programs to better target interventions for HIV, TB, and opportunistic infections, as long as the work remains within non-research programmatic boundaries.

The announcement also situates grantee work within Global Health Initiative style principles, focusing on coordination, integration, and efficiency. Applicants should expect active collaboration and potentially being asked to participate in coordinated activities that improve alignment across partners and across health domains. The listed expectations include adopting a woman- and girl-centered approach; increasing impact through strategic coordination and integration; leveraging multilateral organizations, global health partnerships, and private sector engagement; encouraging country ownership through country-led plans; investing in sustainability via broader health systems strengthening; improving metrics, monitoring, and evaluation; and promoting innovation and development, with the clear caveat that research itself is not supported through this specific award.

At the practical level, the opportunity is driven by a clear problem statement: providing quality laboratory services and reliable diagnostic testing is difficult in many low-resource settings, yet it is essential for accurate clinical diagnosis, effective infectious disease surveillance, and sound public health policy. The grant frames good laboratory practice as cost-effective and central to better patient care, improved confidence in testing, and stronger systems overall. In short, the supplement is meant to help countries strengthen the laboratory backbone that makes HIV programs work, from diagnosing infection to monitoring treatment and ensuring safer blood supplies.

Key administrative details include that the sponsor is the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), under a discretionary cooperative agreement mechanism (meaning CDC is expected to have substantial involvement during implementation). The funding opportunity number is CDC RFA GH13-13660302SUPP16, with CFDA 93.067. The posted award ceiling is $1,500,000, with one expected award. The opportunity was created August 23, 2016, and the original closing date listed is October 22, 2016 (applications due by 11:59 p.m. Eastern Time). Eligibility is described broadly as "Others" with additional clarification referenced in the full eligibility text of the notice.

Frequently Asked Questions (FAQs)

1) What is this funding opportunity?

This opportunity is a CDC cooperative agreement supplement under PEPFAR focused on expanding and strengthening laboratory systems in resource-limited countries to improve HIV/AIDS prevention, treatment, and care outcomes.

2) Who is the sponsoring agency?

The sponsor is the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC).

3) What is the funding opportunity number and CFDA number?

The funding opportunity number is CDC RFA GH13-13660302SUPP16, and the CFDA number is 93.067.

4) What type of award mechanism is this?

This is a discretionary cooperative agreement supplement. A cooperative agreement typically means CDC is expected to have substantial involvement during implementation.

5) What is the main purpose of the award?

The core purpose is public health program improvement (not research). Funding is intended to support activities that prevent or control disease and improve health services, with an emphasis on strengthening diagnostic and laboratory capacity.

6) Is research allowed under this award?

No. Research is explicitly not allowed under this mechanism. However, certain non-research activities that may look research-like operationally can be supported when they are used for program implementation and improvement.

7) What kinds of non-research activities may be supported?

Examples mentioned include formative assessments, surveys, routine disease surveillance, program monitoring and evaluation, and field evaluation of diagnostic tests, as long as they are for program implementation and improvement rather than research.

8) How does this opportunity relate to PEPFAR?

The supplement sits within PEPFAR's broader mandate to deliver immediate, comprehensive, evidence-based action against the global HIV epidemic and to build durable local capacity.

9) What is meant by the "3,12,12" framing mentioned in the announcement?

The program is framed around major PEPFAR targets from the reauthorization era, often summarized as "3,12,12": treating millions of people with antiretroviral therapy, providing care to millions affected by HIV (including orphans and vulnerable children), and preventing millions of new infections.

10) Why are laboratories emphasized in this program?

Laboratories are treated as foundational to a functioning health system rather than a stand-alone technical project. Strengthening labs supports accurate diagnosis, treatment monitoring, surveillance, and broader public health policy.

11) What problem is this funding trying to address?

The announcement highlights that providing quality laboratory services and reliable diagnostic testing is difficult in many low-resource settings, yet essential for accurate clinical diagnosis, effective infectious disease surveillance, and sound public health policy.

12) What outcomes is laboratory strengthening expected to support?

The grant frames improved laboratory practice as cost-effective and central to better patient care, improved confidence in testing, and stronger systems overall, including safer blood supplies and improved treatment monitoring.

13) Which countries or settings are the focus?

The opportunity is aimed at resource-limited countries, with PEPFAR implementation described as country-tailored and aligned with national strategies.

14) How are program activities expected to align with country plans?

Activities are described as aligned with national strategies and designed in collaboration with host governments and partners, fitting within each country's strategic plan and partnership framework.

15) Who leads PEPFAR implementation as described in the opportunity?

Under the leadership of the U.S. Global AIDS Coordinator, CDC works with host governments and partners to assess country needs and design customized assistance.

16) Does CDC focus on many program areas in each country?

The announcement notes that CDC typically concentrates on a small number of major program areas per country to improve focus and effectiveness, with laboratory strengthening positioned as cross-cutting support.

17) What prevention priorities are highlighted?

Prevention priorities mentioned include scaling confidential counseling and testing linked to evidence-based behavior change and strengthening programs to reduce mother-to-child transmission.

18) What care and treatment priorities are highlighted?

Care and treatment priorities include improving management of sexually transmitted infections (STIs), enhancing laboratory diagnostic capacity, strengthening the diagnosis and treatment of opportunistic infections, and supporting antiretroviral therapy services.

19) How is tuberculosis (TB) addressed in this opportunity?

TB is called out as a major intercurrent disease affecting HIV-infected patients, alongside broader priorities to improve diagnosis and treatment of opportunistic infections and support HIV care and treatment programs.

20) What surveillance and national program management priorities are included?

The opportunity emphasizes expanding HIV/STI/TB surveillance and strengthening laboratory support for surveillance, diagnosis, treatment monitoring, and blood safety screening.

21) Does the opportunity support blood safety activities?

Yes. Strengthening laboratory support for blood safety screening is specifically mentioned as part of the surveillance and national program management priority area.

22) Are program development, validation, or evaluation activities allowed?

Yes, the announcement acknowledges the value of developing, validating, and evaluating public health programs to better target interventions for HIV, TB, and opportunistic infections, provided the work remains within non-research programmatic boundaries.

23) What collaboration and coordination expectations are described?

Applicants should expect active collaboration and may be asked to participate in coordinated activities that improve alignment across partners and health domains, consistent with Global Health Initiative style principles around coordination, integration, and efficiency.

24) What cross-cutting principles are highlighted for implementation?

Listed expectations include adopting a woman- and girl-centered approach; increasing impact through strategic coordination and integration; leveraging multilateral organizations, global health partnerships, and private sector engagement; encouraging country ownership through country-led plans; investing in sustainability via broader health systems strengthening; improving metrics, monitoring, and evaluation; and promoting innovation and development, with the caveat that research is not supported by this award.

25) What is the award ceiling and how many awards are expected?

The posted award ceiling is $1,500,000, and one award is expected.

26) What are the key dates listed in the announcement?

The opportunity was created on August 23, 2016. The original closing date listed is October 22, 2016, with applications due by 11:59 p.m. Eastern Time.

27) Who is eligible to apply?

Eligibility is described broadly as "Others," with additional clarification referenced in the full eligibility text of the notice.

28) What does it mean that this is a supplement?

It is described as a cooperative agreement supplement under PEPFAR, indicating it is an add-on funding action associated with an existing cooperative agreement context rather than a standalone research grant.

29) What is the practical focus of funded work?

The emphasis is on applied, real-world work that strengthens service delivery and decision-making, particularly by improving diagnostic and laboratory capacity that underpins HIV programs, surveillance, and policy.

30) Can activities trigger human subjects or similar reviews even if research is not allowed?

The announcement notes that some supported non-research activities can resemble research operationally and that institutional processes (such as human subjects review) may sometimes be triggered by the nature of data collection, even though the mechanism does not support research.

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