Opportunity Information: Apply for RFA HL 10 026
Apply for RFA HL 10 026
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Programs of Excellence in Glycosciences (P01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.839 Blood Diseases and Resources Research.
- This funding opportunity was created on Dec 9, 2009 and posted on Dec 9, 2009.
- Applicants must submit their applications by May 10, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $12,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Independent school districts Public housing authorities/Indian housing authorities Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education State governments County governments Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Programs of Excellence in Glycosciences (PEG) (RFA HL 10 026) is a National Institutes of Health opportunity issued by the National Heart, Lung, and Blood Institute (NHLBI) to accelerate the practical use of glycosciences in heart, lung, and blood research. The central aim is translation: moving emerging discoveries about glycans and glycan-related biology into new diagnostics and clinically relevant applications, while also building long-term research capacity in this space. A major theme is developing investigators who can comfortably work across both glycan chemistry and glycan biology, so that glycoscience tools and thinking become more routine in NHLBI-relevant research areas rather than remaining highly specialized.
The funding uses the NIH Program Project Grant mechanism (P01), meaning applications must be organized around a coherent, complex biomedical theme or research question addressed through multidisciplinary collaboration. A key structural requirement is that each application include at least three interrelated research projects that clearly complement one another, bringing different scientific disciplines to bear on the same overarching problem. In addition to the research projects, the PEG program expects applicants to build shared infrastructure that strengthens glycoscience-enabled research across the program, not just within a single project.
Two cores are emphasized as essential components. First, a shared resources core is expected to increase productivity and functional capacity by providing enabling resources that multiple projects can use, supporting broader adoption and effective application of glycosciences approaches within the program. Second, and especially distinctive for this initiative, applicants must establish a glycosciences skills development core. This core is intended to provide high-quality, specialized courses and training opportunities focused on applying glycosciences to heart, lung, and blood research, with the explicit goal of nurturing and developing new investigators and creating a sustainable pipeline of scientists with cross-disciplinary fluency.
From a funding and scale perspective, NHLBI planned to commit about $12 million in total costs for fiscal year 2011 and anticipated making roughly four to five P01 awards under this announcement. The opportunity was posted December 9, 2009, with an application closing date of May 10, 2010, and it was later archived June 10, 2010. The activity category is Health, and it is associated with CFDA 93.839 (Blood Diseases and Resources Research). Cost sharing or matching is not required.
Eligibility is broad and includes many types of domestic organizations that can conduct and manage large, multi-project research programs, such as public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), small businesses, for-profit organizations (other than small businesses), state and local governments, special district governments, public housing authorities/Indian housing authorities, and tribal organizations, including federally recognized tribal governments. The announcement also notes eligibility for a range of specialized institution types and regional entities, including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, tribally controlled colleges and universities, and U.S. territories or possessions, among others.
In practical terms, the PEG P01 is designed for teams ready to form new partnerships that connect glycoscience expertise with NHLBI mission areas, build shared resources that multiple projects can leverage, and formally train researchers so the field gains durable capacity. The program is not just about producing results in a single lab; it is structured to create an integrated research-and-training ecosystem that makes glycosciences more accessible and impactful for heart, lung, and blood science.
Frequently Asked Questions (FAQs)
What is the Programs of Excellence in Glycosciences (PEG) opportunity?
Programs of Excellence in Glycosciences (PEG) (RFA HL 10 026) is a National Institutes of Health (NIH) funding opportunity issued by the National Heart, Lung, and Blood Institute (NHLBI). Its purpose is to accelerate the practical use of glycosciences in heart, lung, and blood research, with a strong focus on translation into diagnostics and clinically relevant applications.
Which NIH institute is sponsoring this announcement?
The opportunity is issued by the National Heart, Lung, and Blood Institute (NHLBI) under the National Institutes of Health (NIH).
What is the central goal of PEG?
The central aim is translation: moving emerging discoveries about glycans and glycan-related biology into new diagnostics and clinically relevant applications, while also building long-term research capacity in glycosciences within NHLBI-relevant research areas.
What research areas is PEG intended to impact?
PEG is designed to advance glycosciences in research aligned with NHLBI mission areas, specifically heart, lung, and blood research.
What does the announcement mean by “translation” in this context?
Within this opportunity, translation refers to converting discoveries about glycans and glycan-related biology into practical outputs such as new diagnostics and clinically relevant applications, rather than keeping the work purely exploratory or highly specialized.
What funding mechanism is used for PEG?
PEG uses the NIH Program Project Grant mechanism (P01), which is intended for complex, multidisciplinary biomedical programs organized around a coherent theme or major research question.
What does it mean that this is a P01 “Program Project Grant”?
A P01 application must be structured as a coordinated, multi-project program where multiple interrelated research projects work together on one overarching problem. The design emphasizes multidisciplinary collaboration and a unified theme rather than independent, disconnected projects.
How many research projects are required in a PEG P01 application?
Each application must include at least three interrelated research projects that complement one another and bring different scientific disciplines to bear on the same overarching problem.
Do the research projects need to be connected to each other?
Yes. The announcement requires at least three interrelated projects that clearly complement one another and contribute to a single coherent program theme.
Is PEG intended to support only a single lab’s work?
No. PEG is described as building an integrated research-and-training ecosystem. It is structured to create shared resources and formal training that strengthen glycoscience-enabled research across the entire program, not just within one project or one lab.
What kind of shared infrastructure is expected?
Beyond the required research projects, the program expects applicants to build shared infrastructure that strengthens glycoscience-enabled research across the program, so that multiple projects can leverage common resources and capabilities.
What are the two emphasized core components in PEG?
The announcement emphasizes two essential cores: (1) a shared resources core and (2) a glycosciences skills development core.
What is the purpose of the shared resources core?
The shared resources core is expected to increase productivity and functional capacity by providing enabling resources that multiple projects can use, supporting broader adoption and effective application of glycosciences approaches within the program.
What is the glycosciences skills development core?
The glycosciences skills development core is a required and distinctive element of this initiative. It is intended to deliver high-quality, specialized courses and training opportunities focused on applying glycosciences to heart, lung, and blood research.
Who is the training core meant to support?
The skills development core is explicitly intended to nurture and develop new investigators and to create a sustainable pipeline of scientists who are fluent across disciplines relevant to glycosciences and NHLBI mission areas.
What investigator profile is PEG trying to develop?
A major theme is developing investigators who can work comfortably across both glycan chemistry and glycan biology, helping make glycoscience tools and approaches more routine in heart, lung, and blood research rather than remaining highly specialized.
How much funding did NHLBI plan to commit for this opportunity?
NHLBI planned to commit about $12 million in total costs for fiscal year 2011 under this announcement.
How many awards were anticipated?
NHLBI anticipated making roughly four to five P01 awards under this announcement.
What are the key dates for this opportunity?
The opportunity was posted on December 9, 2009. The application closing date was May 10, 2010. It was later archived on June 10, 2010.
Is this opportunity currently open?
No. Based on the provided information, it was archived on June 10, 2010, and the application closing date was May 10, 2010.
What is the activity category for this opportunity?
The activity category is Health.
What CFDA number is associated with PEG?
The opportunity is associated with CFDA 93.839 (Blood Diseases and Resources Research).
Is cost sharing or matching required?
No. Cost sharing or matching is not required for this opportunity.
What types of organizations are eligible to apply?
Eligibility is broad and includes many domestic organization types capable of conducting and managing large, multi-project research programs. Examples listed include public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3)), small businesses, for-profit organizations (other than small businesses), and various government and tribal entities.
Are small businesses eligible?
Yes. Small businesses are listed among the eligible applicants.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed as eligible.
Are state and local governments eligible to apply?
Yes. State and local governments are listed as eligible organization types.
Are tribal organizations eligible?
Yes. Tribal organizations, including federally recognized tribal governments, are listed as eligible.
Are U.S. territories or possessions mentioned as eligible?
Yes. The announcement notes eligibility for regional entities including U.S. territories or possessions, among others.
Are Minority Serving Institutions (MSIs) specifically included?
Yes. The announcement specifically mentions eligibility for institution types such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, and tribally controlled colleges and universities.
What kind of team structure does PEG encourage?
PEG is designed for teams ready to form partnerships that connect glycoscience expertise with NHLBI mission areas, coordinate at least three complementary projects, and build shared resources and training that benefit the full program.
What makes this PEG initiative distinctive compared with a typical multi-project research program?
A particularly distinctive requirement is the glycosciences skills development core, which formalizes specialized training with the explicit goal of developing new investigators and creating a durable pipeline of cross-disciplinary scientists.
What is the overall outcome PEG is trying to create?
In addition to producing research results, PEG is structured to create durable capacity: shared infrastructure, broader adoption of glycosciences approaches across projects, and a sustainable training pathway so glycosciences becomes more accessible and impactful in heart, lung, and blood science.
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