Opportunity Information: Apply for PA 09 228
Apply for PA 09 228
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Proteomics in Auditory Developmental and Disease Processes (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders.
- This funding opportunity was created on Jul 6, 2009 and posted on Jul 6, 2009.
- Applicants must submit their applications by Sep 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Private institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Independent school districts Special district governments City or township governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) County governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The grant opportunity "Proteomics in Auditory Developmental and Disease Processes (R01)" (Funding Opportunity Number PA-09-228) is a National Institutes of Health program issued through the National Institute on Deafness and Other Communication Disorders (NIDCD). Its core goal is to support research projects that use proteomics approaches to better understand how the auditory system develops and how auditory diseases and disorders arise or progress. In practical terms, this means the FOA is looking for R01-level studies that investigate proteins and protein networks involved in hearing, with an emphasis on how changes in the proteome relate to normal developmental processes, pathological mechanisms, or both. The program sits within the NIH mission area tied to CFDA 93.173 (Research Related to Deafness and Communication Disorders), reflecting its focus on hearing and communication health.
This FOA uses the NIH Research Project Grant (R01) mechanism, which is typically intended for more mature, hypothesis-driven projects with a well-developed research plan and the ability to support multi-year work. The announcement also notes that it runs in parallel with another FOA of the same scientific scope that uses the R21 mechanism (PA-06-366). The parallel structure is essentially NIH signaling that it will support the same general scientific topic through two different pathways: the R01 for full-scale projects and the R21 for earlier-stage, more exploratory studies. Applicants are expected to choose the mechanism that best fits their project maturity, aims, and level of preliminary data.
Funding levels and the number of awards are not fixed in advance. Instead, NIH indicates that award size and duration will vary depending on the scientific scope and needs of each proposed project. The total amount ultimately awarded, along with how many projects are supported, depends on standard NIH factors such as which mechanisms are used, the overall quality of the applications, the proposed project periods, and the requested budgets. In other words, there is no guaranteed pot size described here; funding outcomes are driven by the application pool and peer review outcomes, consistent with typical NIH R01 competitions. The FOA explicitly states there is no cost sharing or matching requirement, which means applicants are not required to commit non-federal funds to be eligible or competitive.
Eligibility is broad and includes many common applicant types across academia, government, nonprofit, and industry. Eligible applicants include public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) organizations), small businesses, for-profit organizations other than small businesses, and multiple levels of government (state, county, city/township, special district governments, and certain school districts). The eligibility list also extends to tribal governments and tribal organizations, public housing authorities/Indian housing authorities, regional organizations, and U.S. territories or possessions. The announcement further clarifies additional eligible entities, including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, and non-U.S. entities (foreign organizations). This wide eligibility reflects NIH’s interest in drawing strong proteomics and auditory science expertise from many sectors and organizational types, including international contributors.
From an administrative standpoint, the opportunity was posted on July 6, 2009, with an original and final closing date of September 7, 2012, and an archive date of October 8, 2012. That timeline indicates the FOA is no longer active, but it remains useful as a reference point for how NIDCD framed its priorities around proteomics and auditory development/disease during that period. The full announcement was hosted through the NIH Grants Guide (linked in the listing), and NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or technical linking issues rather than a program-specific scientific contact in the excerpt provided.
Overall, PA-09-228 is best understood as an NIH/NIDCD invitation for comprehensive R01 research proposals that apply proteomics to questions in hearing science, spanning both developmental biology of the auditory system and mechanisms of auditory disease. It offers flexibility in project scope and budgeting (within NIH norms), is open to a wide range of institution types including foreign organizations, and is paired with an R21 companion announcement to accommodate projects at different stages of development.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled "Proteomics in Auditory Developmental and Disease Processes (R01)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PA-09-228.
Which agency and institute issued this FOA?
This is a National Institutes of Health (NIH) program issued through the National Institute on Deafness and Other Communication Disorders (NIDCD).
What is the main goal of PA-09-228?
The core goal is to support research projects that use proteomics approaches to better understand how the auditory system develops and how auditory diseases and disorders arise or progress.
What kinds of studies does this FOA seek to support?
The FOA is focused on R01-level studies that investigate proteins and protein networks involved in hearing, with an emphasis on how changes in the proteome relate to normal developmental processes, pathological mechanisms, or both.
What scientific area or mission category does this relate to?
The program sits within the NIH mission area tied to CFDA 93.173, "Research Related to Deafness and Communication Disorders," reflecting its focus on hearing and communication health.
What grant mechanism does PA-09-228 use?
This FOA uses the NIH Research Project Grant (R01) mechanism.
What does it mean that this is an R01 opportunity?
In this context, R01 indicates a mechanism typically intended for more mature, hypothesis-driven projects with a well-developed research plan and the ability to support multi-year work.
Is there a related or companion funding opportunity?
Yes. The announcement notes it runs in parallel with another FOA of the same scientific scope that uses the R21 mechanism: PA-06-366.
How should an applicant decide between the R01 (PA-09-228) and the R21 (PA-06-366)?
Applicants are expected to choose the mechanism that best fits their project maturity, aims, and level of preliminary data. The R01 is positioned for full-scale projects, while the parallel R21 is positioned for earlier-stage, more exploratory studies.
Are funding amounts and the number of awards predetermined?
No. Funding levels and the number of awards are not fixed in advance. NIH indicates that award size and duration will vary depending on the scientific scope and needs of each proposed project.
What factors influence the final number of awards and total funding?
The total amount awarded and how many projects are supported depends on standard NIH factors such as the mechanisms used, the overall quality of the applications, the proposed project periods, and the requested budgets.
Does this FOA require cost sharing or matching funds?
No. The FOA explicitly states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) organizations), small businesses, for-profit organizations other than small businesses, and multiple levels of government.
What types of government entities are eligible?
Eligible government applicants include state governments, county governments, city or township governments, special district governments, and certain school districts.
Are tribal entities eligible to apply?
Yes. The eligibility list includes tribal governments and tribal organizations.
Are U.S. territories or possessions eligible?
Yes. The eligibility list includes U.S. territories or possessions.
Are public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are included as eligible applicants.
Are regional organizations eligible?
Yes. Regional organizations are listed as eligible applicants.
Are minority-serving institutions specifically included?
Yes. The announcement clarifies additional eligible entities including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly included among eligible entities.
Are federal agencies eligible to apply?
Yes. The announcement includes eligible federal agencies among additional eligible entities.
Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility list includes non-U.S. entities (foreign organizations), indicating international contributors can be eligible under this FOA.
When was this FOA posted?
The opportunity was posted on July 6, 2009.
What were the closing dates for this FOA?
The original and final closing date was September 7, 2012.
When was the FOA archived?
The archive date was October 8, 2012.
Is PA-09-228 still active?
No. Based on the provided timeline (final closing date in 2012 and archive date in 2012), this FOA is no longer active.
Where was the full announcement hosted?
The full announcement was hosted through the NIH Grants Guide (as referenced in the listing).
What contact support is mentioned in the excerpt?
NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or technical linking issues, rather than a program-specific scientific contact in the excerpt provided.
How should this FOA be understood at a high level?
PA-09-228 can be understood as an NIH/NIDCD invitation for comprehensive R01 research proposals that apply proteomics to questions in hearing science, spanning both auditory system development and mechanisms of auditory disease, with flexibility in project scope and budgeting (within NIH norms) and broad eligibility, including foreign organizations.
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