PSIBiology Knowledgebase (U01) | Apply Online

Opportunity Summary:

The PSIBiology Knowledgebase (U01) funding opportunity (RFA-GM-10-004) is a National Institutes of Health program, run through the National Institute of General Medical Sciences (NIGMS), aimed at supporting a single awardee to operate and further develop the PSIBiology Knowledgebase. The central idea is to keep a high-value, community-facing information hub running for the PSIBiology program, so that the results coming out of PSIBiology projects are organized, searchable, and broadly usable by scientists outside the immediate network. In practical terms, the Knowledgebase is positioned as one of the core components of the larger PSIBiology network, with responsibilities that go beyond simple data hosting to include curation, presentation, and active communication with the research community.

The purpose emphasizes two connected goals: first, maintaining and enhancing the Knowledgebase as an infrastructure resource that supports NIGMS-funded PSIBiology projects; and second, maximizing the impact of PSIBiology by making its research outputs widely available and understandable to other scientists. The solicitation expects applicants to describe concrete plans aligned with the objectives laid out in the full Funding Opportunity Description (Part II, Section I of the FOA). While the short summary does not list those objectives in detail, it is clear the project is meant to function as a central clearinghouse for PSIBiology information and as a platform for outreach, meaning the awardee should be prepared to gather input from the broader scientific community, respond to community needs, and iteratively improve the resource so it stays relevant and useful.

This opportunity uses the U01 cooperative agreement mechanism, which signals that NIH will have substantial scientific and programmatic involvement during the project rather than acting as a hands-off funder. The awardee is expected to operate as an active partner in the PSIBiology initiative, including formal participation on the PSIBiology network Steering Committee. That role implies ongoing coordination with other PSIBiology investigators and NIH staff, shared planning, and joint responsibility for how the overall initiative is managed and presented to the community. Applicants should therefore be prepared for collaborative governance, regular reporting and coordination, and alignment with network-wide priorities and timelines.

Funding is described as up to $2.8 million in annual total costs, with exactly one award anticipated. There is no cost sharing or matching requirement listed. The opportunity is categorized as discretionary funding, with the activity category listed under health, and the CFDA number provided as 93.859 (Biomedical Research and Research Training). Key dates in the announcement indicate it was posted and created on May 13, 2009, with an original and current closing date of July 17, 2009, and an archive date of August 17, 2009, which collectively place it as a time-bounded competition with a defined submission window.

Eligibility is broad and spans many organizational types across government, academia, nonprofit, and private sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with or without 501(c)(3) status (as specified), for-profit organizations (other than small businesses are explicitly listed, and small businesses are also listed), as well as multiple levels of government entities such as state governments, county governments, city or township governments, special district governments, and independent school districts. The eligibility language also explicitly includes public housing authorities and Indian housing authorities, federally recognized Native American tribal governments, and Native American tribal organizations that are not federally recognized. Additional eligible applicants named include U.S. territories or possessions, regional organizations, faith-based or community-based organizations, certain minority-serving institutions (including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities), and eligible agencies of the federal government. The wide eligibility net suggests NIH was primarily focused on securing an organization with the right technical, scientific, and community-engagement capabilities to run a national-scale knowledge resource rather than limiting the competition to a narrow institutional class.

From an applicant standpoint, the core expectations can be summarized as: operate a stable and accessible Knowledgebase; enhance it over time so it better serves PSIBiology and the broader scientific community; and conduct outreach that both informs the community about PSIBiology outputs and actively solicits feedback to increase program impact. Because the award is cooperative and tied into network leadership via the Steering Committee, a successful proposal would typically need to demonstrate not just technical competence (data integration, user-facing tools, reliability, and long-term maintenance planning) but also strong coordination skills, clear plans for stakeholder engagement, and a strategy for ensuring PSIBiology research products are findable and usable by scientists who were not involved in generating them.

The sponsoring agency is NIH, with NIGMS as the institute managing the opportunity. The announcement points to the full FOA text via the NIH grants website and provides NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues, indicating the canonical details and any nuanced requirements are contained in the full RFA document.

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