Psychosocial and Behavioral Mechanisms in Bariatric Surgery (R01) | Apply Online

Opportunity Summary:

Psychosocial and Behavioral Mechanisms in Bariatric Surgery (R01) (RFA-DK-16-017) is a National Institutes of Health grant opportunity, administered under HHS/NIH, that funds research focused on the psychological, social, and behavioral drivers of outcomes in people undergoing bariatric surgery. The central idea is to move beyond surgical technique and physiology alone by carefully measuring factors such as mental health, eating behavior patterns, self-regulation, adherence, social support, motivation, stress, substance use risk, and other real-world behaviors that can shape whether surgery leads to durable benefits or to setbacks over time.

The FOA specifically calls for studies that examine mechanisms of behavior change around bariatric surgery and connect those mechanisms to post-surgical success and risk. In practical terms, it supports research that can explain why some patients achieve strong, sustained weight loss and health improvements, while others experience sub-optimal weight loss, weight regain, or adverse metabolic, physiological, or behavioral outcomes in the short or long term. A key emphasis is on identifying measurable behavioral and psychological characteristics that can predict risk trajectories before problems fully emerge, rather than only describing outcomes after the fact.

Two major goals drive the announcement. First, it aims to improve risk identification: building evidence that helps clinicians and researchers determine who is more likely to struggle with weight loss maintenance, regain weight, or encounter negative health or behavioral consequences after surgery, based on psychosocial and behavioral profiles. Second, it aims to inform new or improved interventions and clinical approaches that could be delivered before and/or after surgery to reduce risk and improve outcomes. This includes generating knowledge that could support more tailored care plans, better matching of patients to specific procedures or follow-up strategies, and development of targeted behavioral or psychosocial treatments designed to address the mechanisms that undermine long-term success.

This opportunity uses the NIH R01 research project grant mechanism, meaning it is intended for substantial, hypothesis-driven projects with clearly defined aims and rigorous methods. The maximum award amount listed is an annual ceiling of $500,000, and the FOA anticipated making about two awards, indicating a competitive, targeted funding round. The opportunity falls under the Food and Nutrition and Health activity area and is associated with CFDA numbers 93.847 (and also lists 93.847 in the source data set), reflecting its placement within NIH health research funding.

Eligibility is broad and includes many common applicant types across the public, private, and nonprofit sectors. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and additional entities as described in the FOA’s eligibility notes. This broad eligibility signals NIH’s interest in attracting multidisciplinary teams from academic medical centers, behavioral science groups, healthcare systems, and other research-capable organizations.

Key administrative details in the listing include the original and current closing date of April 14, 2016, a posted and creation date of November 20, 2015, and the sponsoring agency identified as HHS-NIH. Overall, the grant opportunity is designed to strengthen the science base for understanding behavioral and psychosocial pathways that influence bariatric surgery outcomes, with the longer-term intent of enabling earlier risk detection and more personalized, effective pre- and post-surgical care.

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