Opportunity Information: Apply for RFA HL 11 033
Apply for RFA HL 11 033
- The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "Psychosocial Stress and Behavior Integration of Behavioral and Physiological Processes (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.142 NIEHS Hazardous Waste Worker Health and Safety Training 93.143 NIEHS Superfund Hazardous SubstancesBasic Research and Education 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research 93.361 Nursing Research 93.389 National Center for Research Resources 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance 93.989 International Research and Research Training.
- This funding opportunity was created on Aug 17, 2010 and posted on Aug 17, 2010.
- Applicants must submit their applications by Oct 14, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,325,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $400,000.00 in funding.
- Eligible applicants include: Private institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Special district governments Independent school districts For profit organizations other than small businesses City or township governments Native American tribal organizations (other than Federally recognized tribal governments) County governments Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Psychosocial Stress and Behavior: Integration of Behavioral and Physiological Processes (R01) funding opportunity (RFA-HL-11-033) is a National Institutes of Health (NIH) announcement released through the Basic Behavioral and Social Sciences Opportunity Network (OppNet). Its central goal is to support research that explains, in a mechanistic and integrated way, how psychosocial stressors connect to human behavior and how those stress-behavior links can ultimately shape biological function, health outcomes, and disease risk. The emphasis is not just on documenting that stress and behavior are related, but on unpacking the pathways that produce those relationships, including the possibility that the pathways run in both directions (for example, stress changing behavior, and behavior also changing exposure to stress or physiological stress responses).
The FOA encourages applicants to propose innovative, integrative studies that bring together psychological factors, social factors, and environmental contexts to explain how stressors become coupled with behavioral patterns and how those behavioral patterns, in turn, interact with physiological processes. Projects are encouraged to use model systems and longitudinal designs, reflecting NIH interest in studies that can move beyond one-time snapshots and instead track change over time, clarify temporal ordering, and identify potential causal mechanisms. In practical terms, competitive applications would likely propose measurement strategies that capture both behavioral outcomes (such as sleep, diet, physical activity, substance use, treatment adherence, coping behaviors, or social behavior) and physiological processes (such as neuroendocrine activity, cardiovascular reactivity, immune or inflammatory processes, or other biomarkers), while explicitly testing how stress-related exposures translate into behavioral and biological changes.
A notable feature of the announcement is its interest in moderators and sources of heterogeneity: NIH signals that it values research examining why stress affects some people differently than others. The FOA specifically highlights demographic moderators like age, gender/sex, and ethnicity, as well as psychological characteristics such as vulnerability and resilience. It also calls out risk factors, early life exposures, and environmental conditions, including exposures to toxicants, suggesting a broad view of "environment" that includes both social environments (for example, neighborhood conditions, family strain, work stress, discrimination) and physical environments (for example, pollutants or hazardous exposures) that may intensify or alter stress-behavior-physiology links. Overall, the intended payoff is a deeper understanding of the psychological, environmental, and social processes that connect psychosocial stress to behavior and, through those behaviors and stress-responsive biological pathways, to health and disease.
The mechanism of support is the NIH Research Project Grant (R01), which is the standard, investigator-driven mechanism for hypothesis-based research projects. The posted award ceiling is $400,000 (as listed in the opportunity summary). For fiscal year 2011, OppNet anticipated committing an estimated total of about $1,325,000 in total costs (direct plus facilities and administrative costs) to support approximately 2 to 3 new awards, with final numbers depending on the quality of the applications and available funds. There is no cost-sharing or matching requirement.
Eligibility is broad and includes a wide range of organizational types. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, as applicable), state and local governments, tribal governments and tribal organizations, U.S. territories or possessions, special district governments, independent school districts, public housing authorities/Indian housing authorities, small businesses, and other for-profit organizations (with small businesses listed separately). The FOA also explicitly mentions additional eligible categories such as historically black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and foreign (non-U.S.) entities.
Key administrative details in the posted record include a posted and creation date of August 17, 2010, with an original and current closing date of October 14, 2010, and an archive date of November 14, 2010. The opportunity is classified as discretionary, uses the grant funding instrument, and is associated with multiple CFDA program areas spanning health and biomedical research domains (including, for example, mental health, substance use, cardiovascular and lung diseases, environmental health, aging, child health, and others), reflecting the cross-cutting nature of stress-behavior-physiology research. For full announcement text, the listing points to the NIH Grants Guide page at http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-11-033.html, and includes NIH Office of Extramural Research (OER) contact information for access or linking issues.
Frequently Asked Questions (FAQs)
What is the name and number of this funding opportunity?
The opportunity is titled Psychosocial Stress and Behavior: Integration of Behavioral and Physiological Processes (R01) and is identified as RFA-HL-11-033.
Which agency is offering this opportunity?
This is a National Institutes of Health (NIH) funding opportunity released through the Basic Behavioral and Social Sciences Opportunity Network (OppNet).
What is the main purpose of the FOA?
The central goal is to support research that explains, in a mechanistic and integrated way, how psychosocial stressors connect to human behavior, and how those stress-behavior links can shape biological function, health outcomes, and disease risk.
Is the emphasis on showing that stress and behavior are related, or on explaining how they are related?
The emphasis is on unpacking the pathways that produce stress-behavior relationships, not simply documenting that stress and behavior are associated.
Does the FOA allow for stress and behavior to influence each other?
Yes. The FOA explicitly highlights the possibility of bidirectional pathways, such as stress influencing behavior and behavior influencing exposure to stress or physiological stress responses.
What kinds of studies does the FOA encourage?
The FOA encourages innovative, integrative studies that combine psychological factors, social factors, and environmental contexts to explain how stressors become linked with behavioral patterns and how those patterns interact with physiological processes.
Are model systems and longitudinal designs encouraged?
Yes. The FOA encourages the use of model systems and longitudinal designs to move beyond one-time snapshots, track change over time, clarify temporal ordering, and help identify potential causal mechanisms.
What behavioral outcomes are examples of what applicants might measure?
The FOA provides examples of behavioral outcomes such as sleep, diet, physical activity, substance use, treatment adherence, coping behaviors, and social behavior.
What physiological processes or biomarkers are examples of what applicants might measure?
The FOA provides examples including neuroendocrine activity, cardiovascular reactivity, immune or inflammatory processes, and other biomarkers.
Does the FOA prioritize integration of behavioral and physiological measures?
Yes. Competitive projects would likely include measurement strategies that capture both behavioral outcomes and physiological processes and explicitly test how stress-related exposures translate into behavioral and biological changes.
Is the FOA interested in why stress affects people differently?
Yes. A notable feature is the emphasis on moderators and heterogeneity, including research on why stress affects some individuals differently than others.
What demographic moderators are specifically highlighted?
The FOA specifically highlights demographic moderators such as age, gender/sex, and ethnicity.
What psychological characteristics are mentioned as potential moderators?
The FOA mentions psychological characteristics such as vulnerability and resilience.
How does the FOA define or frame "environment"?
The FOA takes a broad view of environment, including both social environments (for example, neighborhood conditions, family strain, work stress, discrimination) and physical environments (for example, pollutants or hazardous exposures).
Are early life exposures and risk factors within scope?
Yes. The FOA calls out risk factors, early life exposures, and environmental conditions as relevant to understanding stress-behavior-physiology links.
Are exposures to toxicants considered relevant under this FOA?
Yes. The FOA explicitly mentions environmental conditions including exposure to toxicants.
What is the intended payoff or impact of the research supported?
The intended payoff is a deeper understanding of the psychological, environmental, and social processes linking psychosocial stress to behavior and, through behaviors and stress-responsive biological pathways, to health and disease.
What is the funding mechanism?
The mechanism of support is the NIH Research Project Grant (R01), described as the standard, investigator-driven mechanism for hypothesis-based research projects.
What is the posted award ceiling?
The posted award ceiling in the opportunity summary is $400,000.
How much total funding was OppNet expecting to commit for FY 2011?
For fiscal year 2011, OppNet anticipated committing an estimated total of about $1,325,000 in total costs (direct plus facilities and administrative costs).
How many awards were expected?
Approximately 2 to 3 new awards were anticipated, depending on application quality and available funds.
Is cost-sharing or matching required?
No. The posted record states there is no cost-sharing or matching requirement.
What types of organizations are eligible to apply?
Eligibility is broad and includes: public and private institutions of higher education; nonprofit organizations (including those with and without 501(c)(3) status, as applicable); state and local governments; tribal governments and tribal organizations; U.S. territories or possessions; special district governments; independent school districts; public housing authorities/Indian housing authorities; small businesses; and other for-profit organizations.
Are specific institution types (like HBCUs or Hispanic-serving institutions) mentioned as eligible?
Yes. The FOA explicitly mentions additional eligible categories including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and foreign (non-U.S.) entities.
Are foreign (non-U.S.) organizations eligible?
Yes. The FOA explicitly includes foreign (non-U.S.) entities among eligible applicants.
What are the key dates listed in the posted record?
The posted and creation date is August 17, 2010. The original and current closing date is October 14, 2010. The archive date is November 14, 2010.
What type of opportunity classification and funding instrument are listed?
The opportunity is classified as discretionary, uses the grant funding instrument, and is associated with NIH extramural research administration.
What research areas does this FOA connect to?
The posted record notes multiple CFDA program areas spanning health and biomedical research domains, including examples such as mental health, substance use, cardiovascular and lung diseases, environmental health, aging, and child health, reflecting the cross-cutting nature of stress-behavior-physiology research.
Where can applicants find the full announcement text?
The listing points to the NIH Grants Guide page: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-11-033.html.
Who is listed for contact support related to access or linking issues?
The posted record notes NIH Office of Extramural Research (OER) contact information for access or linking issues.
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