Opportunity Information: Apply for RFA DD 09 005
Apply for RFA DD 09 005
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Public Health Research on Down syndrome (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.283 Centers for Disease Control and PreventionInvestigations and Technical Assistance.
- This funding opportunity was created on Feb 25, 2009 and posted on Feb 25, 2009.
- Applicants must submit their applications by Apr 17, 2009 Letter of Intent Receipt Date March 17, 2009 Application Receipt Date April 17, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $600,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- Eligible Institutions You may submit an application if your organization has any of the following characteristics Public nonprofit organizations Private nonprofit organizations For profit organizations Small, minority, and women owned businesses Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized or state recognized American Indian/Alaska Native tribal governments American Indian/Alaska Native tribally designated organizations Alaska Native health corporations Urban Indian health organizations Tribal epidemiology centers State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Political subdivisions of States (in consultation with States) A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If you are applying as a bona fide agent of a state or local government, you must provide a letter from the state or local government as documentation of your status. Attach this documentation behind the first page of your application form or for electronic applications, use a PDF file and attach as Other Documents and label as appropriate.
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Opportunity Summary:
The Centers for Disease Control and Prevention (CDC) offered this discretionary funding opportunity, titled "Public Health Research on Down syndrome (U01)," under Funding Opportunity Number RFA DD 09 005. It was structured as a cooperative agreement (U01), which typically means the funded projects would be led by the awardees but carried out with substantial CDC involvement or collaboration during planning, execution, and reporting. The purpose of the announcement was to strengthen public health knowledge about Down syndrome by filling key research gaps, with an emphasis on comorbidities and growth outcomes that affect health and healthcare needs over time.
The FOA focused on advancing understanding of comorbidities associated with Down syndrome, especially by generating evidence that can inform prevention, clinical care, and public health decision-making. Two priority research areas were highlighted. The first priority area targeted comorbidities among children and adolescents with Down syndrome, with a specific interest in how risk factors and protective or preventive factors influence whether these conditions occur. Importantly, the CDC explicitly included healthcare utilization as a factor of interest, signaling that proposals could examine how access to care, patterns of medical visits, screening, treatment adherence, care coordination, or other utilization-related measures might affect the development, detection, or management of co-occurring conditions. In practical terms, this area invited research that could clarify which comorbidities are most common in pediatric and adolescent populations with Down syndrome, when they tend to emerge, and what modifiable factors may reduce risk or improve outcomes.
The second priority area centered on the impact of Down syndrome on growth. The FOA called for assessment of growth-related measures including length/height, weight, head circumference, and body mass index (BMI). This emphasis suggests an interest in characterizing growth patterns and trajectories, potentially identifying differences compared with typical development, and understanding how growth relates to health status, comorbidities, and healthcare. Research in this area could support improved growth monitoring and more tailored health guidance for children and adolescents with Down syndrome, especially where standard growth references may not adequately reflect this population.
Financially, the CDC anticipated making two awards, with an estimated total funding amount of $600,000. The ceiling per award was $300,000, and there was no stated award floor. The FOA did not require cost sharing or matching. The activity category was Health, and the CFDA number listed was 93.283 (CDC Investigations and Technical Assistance), indicating the broader federal assistance program through which the funds were administered.
Eligibility was broad and included many types of organizations that could plausibly conduct or support applied public health research. Eligible applicants included public and private nonprofit organizations, for-profit organizations (including small businesses and minority- and women-owned businesses), universities and colleges, research institutions, hospitals, community-based and faith-based organizations, and governmental entities at the state and local level (including U.S. territories and affiliated jurisdictions). The announcement also explicitly included federally or state recognized American Indian/Alaska Native tribal governments and tribally designated organizations, Alaska Native health corporations, urban Indian health organizations, tribal epidemiology centers, and political subdivisions of states in consultation with states. The FOA noted that state or local governments could apply through a bona fide agent, but in that case the applicant had to provide documentation (a letter from the relevant government) confirming bona fide agent status as part of the application package.
Key dates show the FOA was posted on February 25, 2009, with a letter of intent due March 17, 2009, and full applications due April 17, 2009. The opportunity closed on April 17, 2009, and was archived on May 17, 2009. For applicants who had trouble accessing the full announcement, the CDC provided a contact point through its Procurement and Grants Office Technical Information Management (phone 770-488-2700).
Overall, this FOA was designed to produce practical, population-relevant evidence about health complications and growth in children and adolescents with Down syndrome, with the broader public health goal of improving understanding of risks, preventive factors, and healthcare-related influences that shape outcomes for this community.
Frequently Asked Questions (FAQs): CDC "Public Health Research on Down syndrome (U01)" (RFA DD 09 005)
What is the title of this funding opportunity?
The funding opportunity is titled "Public Health Research on Down syndrome (U01)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is RFA DD 09 005.
Who offered this grant opportunity?
This discretionary funding opportunity was offered by the Centers for Disease Control and Prevention (CDC).
What type of award mechanism is used?
The award mechanism is a cooperative agreement (U01). This means projects would be led by the awardees, with substantial CDC involvement or collaboration during planning, execution, and reporting.
What is the overall purpose of the announcement?
The purpose was to strengthen public health knowledge about Down syndrome by filling key research gaps, with an emphasis on comorbidities and growth outcomes that affect health and healthcare needs over time.
What population does the FOA emphasize?
The FOA emphasizes children and adolescents with Down syndrome, particularly in relation to comorbidities and growth outcomes.
What kinds of research topics were emphasized?
The FOA emphasized applied public health research that advances understanding of comorbidities associated with Down syndrome and research that characterizes growth outcomes (such as height and weight measures) in children and adolescents with Down syndrome.
What were the two priority research areas?
The two priority areas were: (1) comorbidities among children and adolescents with Down syndrome, including how risk factors and protective/preventive factors influence occurrence; and (2) the impact of Down syndrome on growth, including assessment of specific growth measures.
What does the FOA mean by "comorbidities" in this context?
In this FOA, comorbidities refer to co-occurring health conditions associated with Down syndrome. The focus is on understanding which conditions are common, when they tend to emerge, and what factors influence their occurrence and outcomes.
What factors related to comorbidities were of interest to CDC?
CDC highlighted interest in risk factors as well as protective or preventive factors that may influence whether comorbidities occur among children and adolescents with Down syndrome.
Was healthcare utilization specifically included as a research factor?
Yes. The FOA explicitly included healthcare utilization as a factor of interest. This signals proposals could examine how access to care and patterns of healthcare use may affect development, detection, or management of co-occurring conditions.
What examples of healthcare utilization measures are consistent with what the FOA describes?
Based on the FOA description, utilization-related measures could include access to care, patterns of medical visits, screening, treatment adherence, care coordination, or other healthcare use measures that might influence comorbidity outcomes.
What growth-related research was encouraged?
The FOA encouraged assessment of growth-related measures and growth patterns/trajectories in children and adolescents with Down syndrome, including how growth relates to health status, comorbidities, and healthcare.
Which growth measures were specifically named?
The FOA specifically named length/height, weight, head circumference, and body mass index (BMI).
What is the intended public health value of the growth research area?
The growth research area was intended to support improved growth monitoring and more tailored health guidance for children and adolescents with Down syndrome, particularly where standard growth references may not adequately reflect this population.
How many awards did CDC anticipate making?
CDC anticipated making two awards.
What was the estimated total funding available?
The estimated total funding amount was $600,000.
What was the maximum amount per award?
The ceiling per award was $300,000.
Was there a minimum (floor) award amount stated?
No. The FOA did not state an award floor.
Was cost sharing or matching required?
No. The FOA did not require cost sharing or matching.
What is the activity category listed for this opportunity?
The activity category was Health.
What CFDA number was associated with this opportunity?
The CFDA number listed was 93.283 (CDC Investigations and Technical Assistance).
Who was eligible to apply?
Eligibility was broad. Eligible applicants included public and private nonprofit organizations, for-profit organizations (including small businesses and minority- and women-owned businesses), universities and colleges, research institutions, hospitals, community-based and faith-based organizations, and state and local governmental entities (including U.S. territories and affiliated jurisdictions).
Were tribal entities and tribal organizations eligible?
Yes. The FOA explicitly included federally or state recognized American Indian/Alaska Native tribal governments and tribally designated organizations, Alaska Native health corporations, urban Indian health organizations, tribal epidemiology centers, and political subdivisions of states in consultation with states.
Could a state or local government apply through another organization?
Yes. The FOA noted that state or local governments could apply through a bona fide agent.
If applying as a bona fide agent, was additional documentation required?
Yes. The applicant had to provide documentation (a letter from the relevant government) confirming bona fide agent status as part of the application package.
When was the FOA posted?
The FOA was posted on February 25, 2009.
Was a letter of intent required, and when was it due?
A letter of intent was due on March 17, 2009.
When were full applications due?
Full applications were due on April 17, 2009.
When did the opportunity close?
The opportunity closed on April 17, 2009.
When was the opportunity archived?
The opportunity was archived on May 17, 2009.
Who could applicants contact if they had trouble accessing the full announcement?
Applicants could contact the CDC Procurement and Grants Office Technical Information Management at 770-488-2700.
What kind of evidence was this FOA aiming to produce?
The FOA aimed to produce practical, population-relevant evidence about health complications (comorbidities) and growth in children and adolescents with Down syndrome to improve understanding of risks, preventive factors, and healthcare-related influences on outcomes.
How does CDC describe the intended use of the research results?
The FOA emphasized generating evidence that can inform prevention, clinical care, and public health decision-making related to Down syndrome.
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