Opportunity Information: Apply for CDC RFA DD15 1507
Apply for CDC RFA DD15 1507
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Public Health Surveillance for the Prevention of Complications of Bleeding Disorders" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.080 Blood Disorder Program Prevention, Surveillance, and Research.
- This funding opportunity was created on May 14, 2015 and posted on Mar 13, 2015.
- Applicants must submit their applications by May 20, 2015 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $4,300,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $4,300,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
- Applicants must provide documentation that HTCs have agreed to collaborate with the awardee and CDC to carry out the strategies and activities relevant to the HTCs that are proposed for this project. This documentation may be in the form of letters of support, letters of agreement, memoranda of understanding, memoranda of agreement, or contracts from or with collaborating HTCs (hereafter referred to collectively as ldquoletters of supportrdquo). Documentation from the regional core center on behalf of the participating HTCs within its region may be provided in place of individual documentation from each HTC. If letters of support are not provided, the applicant will be considered non responsive.
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Opportunity Summary:
Public Health Surveillance for the Prevention of Complications of Bleeding Disorders is a CDC discretionary funding opportunity designed to keep a long-running national surveillance effort going for hemophilia and other congenital bleeding disorders. Congress has supported this work since the 1990s, and since 1996 the CDC has relied on the federal network of Hemophilia Treatment Centers (HTCs) to collect consistent, high-quality data on health indicators that matter most to people living with bleeding disorders. The main idea is straightforward: use standardized data from the HTC network to understand how often serious complications occur, track how those outcomes change over time, and spot emerging safety or public health issues early enough to prevent harm.
The surveillance data collected through participating HTCs is intended to serve several practical public health functions. It is used to measure rates of complications related to bleeding disorders and their treatment, then monitor trends year over year. A major focus is on inhibitors (immune responses that reduce the effectiveness of clotting factor replacement), as well as broader blood and treatment product safety concerns. Beyond monitoring, the dataset supports identification of high-risk populations who may benefit from targeted prevention programs, and it helps flag problems that need additional research attention. In short, the program is meant to produce actionable information, not just academic findings, so that prevention strategies and clinical/public health priorities can be adjusted based on real-world evidence.
This funding opportunity is structured as a cooperative agreement, which typically means the CDC expects to have substantial involvement in the work rather than simply issuing funds and stepping back. The activity category is health, and the associated CFDA number is 93.080 (Blood Disorder Program Prevention, Surveillance, and Research). The FOA anticipates a single award, indicating the CDC is looking for one lead organization to coordinate or manage the surveillance effort in collaboration with the HTC network and the CDC.
Financially, the opportunity lists an estimated total funding amount of $4,300,000, with an award ceiling also set at $4,300,000 and an award floor of $100,000. There is no cost sharing or matching requirement, which lowers the barrier for applicants that might not have non-federal funds available to contribute. The posting date was March 13, 2015, with the closing date of May 20, 2015 (applications due by 11:59 p.m. Eastern Time), and the opportunity was archived on June 19, 2015.
Eligibility is described as unrestricted in general terms (open to any type of entity), but there is an important practical eligibility condition embedded in the requirements. Applicants must document that HTCs have agreed to collaborate with the awardee and the CDC on the strategies and activities proposed for the project. Acceptable documentation includes letters of support or agreement, memoranda of understanding or agreement, or contracts. Notably, documentation can be provided by a regional core center on behalf of the participating HTCs within that region, rather than collecting separate letters from each individual center. However, this documentation is not optional: if letters of support (or equivalent documentation) are not provided, the application is deemed non-responsive and would not be considered.
Overall, the opportunity is aimed at sustaining and strengthening a national public health surveillance system anchored in the hemophilia treatment center network, ensuring the CDC and partners can continue to measure complications, monitor safety and outcomes trends, identify groups at elevated risk, and guide prevention and research priorities based on comprehensive, multi-site data. For additional information, the listed CDC contact for access issues is Meredith Oakley (mco6@cdc.gov).
Frequently Asked Questions (FAQs)
What is the purpose of this CDC funding opportunity?
This opportunity, titled Public Health Surveillance for the Prevention of Complications of Bleeding Disorders, is intended to sustain and strengthen a long-running national surveillance effort focused on hemophilia and other congenital bleeding disorders. The core purpose is to use standardized, high-quality data collected through the national network of Hemophilia Treatment Centers (HTCs) to understand how often serious complications occur, monitor how outcomes change over time, and identify emerging safety or public health issues early enough to prevent harm.
What type of funding mechanism is being used?
The program is structured as a cooperative agreement. This indicates the CDC expects to have substantial involvement in the project activities rather than simply providing funds without ongoing engagement.
What public health problem does the surveillance system focus on?
The surveillance system focuses on complications associated with hemophilia and other congenital bleeding disorders, including complications related to treatment. A major emphasis is placed on inhibitors, which are immune responses that reduce the effectiveness of clotting factor replacement therapy, as well as broader blood and treatment product safety concerns.
What are the main goals of collecting surveillance data through HTCs?
Based on the description provided, the surveillance data is intended to support several practical public health functions, including:
- Measuring rates of complications related to bleeding disorders and their treatment
- Monitoring year-over-year trends in outcomes
- Detecting emerging safety issues or public health concerns related to blood or treatment products
- Identifying high-risk populations who may benefit from targeted prevention programs
- Flagging problems that may require additional research attention
The program is described as producing actionable information to guide prevention strategies and clinical/public health priorities.
Why are Hemophilia Treatment Centers (HTCs) central to this program?
Since 1996, the CDC has relied on the federal network of HTCs to collect consistent and high-quality surveillance data on health indicators that matter to people living with bleeding disorders. The HTC network provides a multi-site foundation for standardized data collection and national-level trend monitoring.
How long has Congress supported this national surveillance effort?
The surveillance effort has been supported by Congress since the 1990s, according to the opportunity description.
What is the activity category for this opportunity?
The activity category is listed as health.
What is the CFDA number associated with this funding opportunity?
The CFDA number provided is 93.080, described as Blood Disorder Program Prevention, Surveillance, and Research.
How many awards does the FOA anticipate making?
The FOA anticipates a single award, meaning the CDC is expecting to fund one lead organization to coordinate or manage the surveillance effort in collaboration with the HTC network and the CDC.
What is the estimated total funding amount?
The estimated total funding amount is $4,300,000.
What are the award ceiling and award floor?
The award ceiling is $4,300,000, and the award floor is $100,000.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is described as unrestricted in general terms (open to any type of entity). However, the opportunity also includes a critical practical condition related to collaboration with Hemophilia Treatment Centers (HTCs).
What collaboration documentation is required with HTCs?
Applicants must document that HTCs have agreed to collaborate with the awardee and the CDC on the strategies and activities proposed for the project. Acceptable documentation includes:
- Letters of support or agreement
- Memoranda of understanding or agreement
- Contracts
Can a regional core center provide documentation on behalf of multiple HTCs?
Yes. The opportunity specifies that documentation can be provided by a regional core center on behalf of the participating HTCs within that region, instead of collecting separate letters from each individual center.
What happens if an application does not include the required HTC collaboration documentation?
If letters of support or equivalent documentation are not provided, the application is deemed non-responsive and will not be considered.
What are the key dates for this opportunity?
- Posting date: March 13, 2015
- Closing date: May 20, 2015 (applications due by 11:59 p.m. Eastern Time)
- Archive date: June 19, 2015
Is this opportunity still open?
No. The opportunity is listed as archived as of June 19, 2015, and the application closing date was May 20, 2015.
What does the program mean by identifying "high-risk populations"?
Within the context provided, identifying high-risk populations refers to using the surveillance dataset to recognize groups who may be more likely to experience serious complications and therefore may benefit from targeted prevention programs.
How is the collected information expected to be used?
The program is described as being designed to generate practical, real-world evidence that can support prevention strategies and help adjust clinical and public health priorities. The emphasis is on actionable surveillance findings rather than academic outcomes alone.
Who is the CDC contact listed for access issues?
The listed CDC contact for access issues is Meredith Oakley at mco6@cdc.gov.
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