Opportunity Information: Apply for PA 13 124
Apply for PA 13 124
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Regional and International Differences in Health and Longevity at Older Ages (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Feb 21, 2013 and posted on Feb 21, 2013.
- Applicants must submit their applications by Sep 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Special district governments Small businesses Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts County governments Public and State controlled institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The grant opportunity titled "Regional and International Differences in Health and Longevity at Older Ages (R21)" (Funding Opportunity Number PA-13-124) is a National Institutes of Health (NIH) aging research funding announcement designed to deepen understanding of why health and longevity among older adults are moving in different directions across places. The core focus is on explaining divergent trends in later-life health and survival, comparing both industrialized countries internationally and different regions within the United States. The announcement is motivated by findings in the scientific literature that have been described as provocative or surprising but not yet fully explained, and it aims to push the field toward clearer, evidence-based explanations for these patterns.
A major emphasis of the opportunity is leveraging the National Institute on Aging (NIA) investment in cross-nationally comparable datasets that allow researchers to make more credible comparisons across countries and across time. Examples highlighted in the announcement include the Health and Retirement Study (HRS) in the United States, the English Longitudinal Study of Ageing (ELSA) in England, the Survey of Health, Ageing and Retirement in Europe (SHARE), and the Human Mortality Database. The intent is not simply to describe differences in outcomes, but to identify underlying drivers, such as differences in disease burden, health behaviors, socioeconomic conditions, policy environments, health care access and quality, neighborhood and environmental exposures, and other structural factors that can shape health trajectories in older age. The overall goal is to generate insights that help explain why older adults in one country, state, or region may be living longer or healthier lives than those elsewhere, even when the countries involved are all considered "industrialized" and broadly comparable.
The announcement encourages a wide range of research approaches and data strategies. Applicants are encouraged to conduct rigorous secondary analyses of existing datasets, propose targeted new data collection where necessary, develop and calibrate measures so that key variables mean the same thing across studies and national contexts, and create innovative survey measures that capture concepts not well measured in current instruments. It also explicitly encourages linkages between survey data and administrative sources, which can strengthen analyses by adding objective records such as claims data, mortality records, employment histories, or other governmental and institutional data sources. While NIA-supported datasets are featured because of their cross-national comparability and established infrastructure, the opportunity is not limited to those resources; applicants may propose any relevant data source or combination of sources, as long as the work advances understanding of regional and international differences in health and longevity at older ages.
From an administrative standpoint, this is a discretionary grant opportunity under NIH, categorized under the funding activity area of health, with the CFDA listing 93.866 (Aging Research). It does not require cost sharing or matching. The posted and creation date were February 21, 2013, and the opportunity ran through a final closing date of September 7, 2016, with an archive date of October 8, 2016. The listed award ceiling is $200,000, indicating a relatively modest budget cap consistent with exploratory or targeted work. Even though the title includes "(R21)," the text of the description notes encouragement of R01 applications; in practice, applicants would need to follow the specific mechanism details in the full FOA to ensure the project scope, duration, and budget align with the allowable grant mechanism requirements.
Eligibility is broad and includes many types of domestic U.S. organizations and governments, as well as foreign entities. Eligible applicants include public and private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) organizations), for-profit organizations (including small businesses and other for-profits), and multiple levels of government such as state, county, city or township, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The eligibility language also explicitly includes a wide range of mission-oriented institutions and community-serving entities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribal colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and Asian American and Native American Pacific Islander-serving institutions (AANAPISIs), as well as faith-based or community-based organizations and eligible federal agencies. Importantly for cross-national aging research, non-U.S. entities (foreign organizations and foreign institutions) are eligible to apply, and foreign components of U.S. organizations are allowed under NIH policy.
In practical terms, a strong application under this announcement would be expected to do more than document that differences exist. It would typically propose a clear analytic plan that explains which mechanisms might be responsible for observed gaps in mortality or healthy aging, why the proposed data can test those mechanisms, and how the work will overcome common problems in cross-place comparisons, such as inconsistent measurement, selection effects, and differences in population composition. Because the FOA highlights measure calibration and cross-study harmonization, applications that carefully address comparability (for example, aligning disability measures, chronic disease definitions, cognition measures, socioeconomic indicators, or health care utilization metrics across countries and surveys) fit squarely within the intent. The contact and full announcement are provided through the NIH grants website, with technical assistance available via the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
Frequently Asked Questions (FAQs)
What is the title and funding opportunity number for this grant?
The opportunity is titled "Regional and International Differences in Health and Longevity at Older Ages (R21)" and the Funding Opportunity Number is PA-13-124.
Which agency is offering this funding opportunity?
This is a National Institutes of Health (NIH) funding announcement in the aging research area, with a major emphasis on resources supported by the National Institute on Aging (NIA).
What is the main purpose of this grant announcement?
The core goal is to deepen understanding of why health and longevity at older ages are trending differently across places. It aims to move beyond documenting differences and toward evidence-based explanations for divergent patterns in later-life health and survival.
What kinds of comparisons does the announcement emphasize?
It emphasizes comparisons across industrialized countries (international comparisons) and comparisons across different regions within the United States.
What types of outcomes are in scope (health and longevity at older ages)?
The focus is on later-life health and survival, including differences in mortality and "healthy aging" across countries, states, or regions.
Does the opportunity focus on describing differences, or explaining them?
The stated intent is not simply to describe differences in outcomes, but to identify underlying drivers and mechanisms that explain why outcomes differ across places and over time.
What kinds of drivers or mechanisms does the FOA highlight as possible explanations?
Examples of potential underlying drivers mentioned include differences in disease burden, health behaviors, socioeconomic conditions, policy environments, health care access and quality, neighborhood and environmental exposures, and other structural factors shaping health trajectories in older age.
What is the role of cross-nationally comparable datasets in this opportunity?
A major emphasis is leveraging NIA investments in cross-nationally comparable datasets to make more credible comparisons across countries and across time.
Which example datasets are explicitly highlighted?
The announcement highlights examples including the Health and Retirement Study (HRS) in the United States, the English Longitudinal Study of Ageing (ELSA) in England, the Survey of Health, Ageing and Retirement in Europe (SHARE), and the Human Mortality Database.
Are applicants limited to using only NIA-supported datasets?
No. While NIA-supported datasets are featured for their comparability and infrastructure, applicants may propose any relevant data source(s) or combination of sources, as long as the work advances understanding of regional and international differences in health and longevity at older ages.
What research approaches are encouraged?
The announcement encourages a wide range of approaches, including rigorous secondary analyses of existing datasets, targeted new data collection where necessary, development and calibration of measures so variables mean the same thing across studies and contexts, and creation of innovative survey measures for concepts not well captured in current instruments.
Does the FOA encourage linking survey data to administrative records?
Yes. It explicitly encourages linkages between survey data and administrative sources to strengthen analyses by adding objective records such as claims data, mortality records, employment histories, or other governmental or institutional data sources.
Why does the FOA emphasize measure calibration and harmonization?
Because cross-place comparisons can be undermined by inconsistent measurement and non-comparable definitions across countries and surveys. The FOA highlights calibration and cross-study harmonization as a way to improve comparability (for example, aligning disability measures, chronic disease definitions, cognition measures, socioeconomic indicators, or health care utilization metrics).
What common cross-country or cross-region comparison problems does the announcement expect applicants to address?
The description points to challenges such as inconsistent measurement, selection effects, and differences in population composition, and implies that strong applications should show how these issues will be handled.
What is the funding activity area and CFDA listing?
The funding activity area is health, and the CFDA listing provided is 93.866 (Aging Research).
Is cost sharing or matching required?
No. The opportunity states that it does not require cost sharing or matching.
What is the award ceiling for this opportunity?
The listed award ceiling is $200,000, consistent with a relatively modest budget cap intended for exploratory or targeted work.
What are the key dates for this funding opportunity?
The posted and creation date were February 21, 2013. The opportunity ran through a final closing date of September 7, 2016, and the archive date was October 8, 2016.
What grant mechanism does this announcement use?
The title includes "(R21)." However, the description also notes encouragement of R01 applications. Applicants would need to follow the full FOA mechanism details to ensure the project scope, duration, and budget align with what is allowable under the chosen mechanism.
Who is eligible to apply?
Eligibility is broad. It includes many types of domestic U.S. organizations and governments, as well as foreign entities, as described in the announcement.
Are U.S. universities and colleges eligible?
Yes. Eligible applicants include public and private institutions of higher education.
Are nonprofits eligible to apply?
Yes. Eligibility includes nonprofits, including both 501(c)(3) and non-501(c)(3) organizations.
Are for-profit organizations eligible?
Yes. Eligibility includes for-profit organizations, including small businesses and other for-profit entities.
Which government entities are listed as eligible?
Examples listed include state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are mission-oriented and community-serving institutions explicitly included?
Yes. The eligibility language explicitly includes institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribal colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and Asian American and Native American Pacific Islander-serving institutions (AANAPISIs), along with faith-based or community-based organizations.
Are foreign organizations eligible?
Yes. Non-U.S. entities (foreign organizations and foreign institutions) are eligible to apply, and foreign components of U.S. organizations are allowed under NIH policy.
What would a strong application generally be expected to include?
Based on the description, a strong application would go beyond documenting differences and present a clear analytic plan that specifies plausible mechanisms, explains why the proposed data can test those mechanisms, and addresses comparability challenges in cross-place analyses (including measurement alignment, selection effects, and differences in population composition).
Where is the full announcement hosted, and where is help available for access issues?
The full announcement and contacts are available through the NIH grants website. For technical assistance related to access or linking issues, the NIH Office of Extramural Research (OER) webmaster is referenced as a support resource.
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