Opportunity Information: Apply for RFA RM 11 016
Apply for RFA RM 11 016
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Regional Comprehensive Metabolomics Resource Cores (RCMRC) (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Dec 2, 2011 and posted on Dec 2, 2011.
- Applicants must submit their applications by Feb 15, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Independent school districts Special district governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments City or township governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Regional Comprehensive Metabolomics Resource Cores (RCMRC) (U24) funding opportunity (RFA-RM-11-016) is a National Institutes of Health (NIH) cooperative agreement program designed to expand U.S. biomedical research capacity in metabolomics. In practical terms, NIH was seeking applications to stand up regional, shared-use resource centers that could provide high-quality metabolomics capabilities to a broad range of investigators, including those who may not already have access to advanced metabolomics platforms, expertise, or standardized workflows. The emphasis is on enabling biological and clinical research uses of metabolomics by building dependable infrastructure, services, and expertise that can be accessed beyond a single lab or department.
Because this is a U24 cooperative agreement, the intent is not simply to provide funds and step back, but to support centers that would operate in close coordination with NIH program staff. Cooperative agreements typically involve a more active partnership with the funding agency than standard research grants, often including expectations around milestone-driven progress, coordination across sites, and alignment with national program goals. Here, the national goal is to strengthen the overall metabolomics ecosystem by creating regional hubs that can deliver comprehensive services and foster consistent practices, training, and community engagement.
The program scope centers on establishing Regional Comprehensive Metabolomics Resource Cores that provide multiple, complementary functions. First, these cores are expected to operate as technology service centers, meaning they would offer access to metabolomics instrumentation, analytical pipelines, and technical support that investigators can use to generate metabolomics data. Second, the FOA explicitly supports pilot and feasibility projects, which are typically small, targeted awards designed to help researchers test ideas, generate preliminary data, and demonstrate the utility of metabolomics for specific biomedical questions. Third, training activities are an integral component, reflecting NIH interest in growing the skilled workforce needed to design metabolomics studies properly, handle biospecimens appropriately, perform robust analytical chemistry and bioinformatics, and interpret results in a biologically meaningful way. Finally, outreach activities are also supported, signaling that these centers are expected to engage the broader research community, raise awareness of metabolomics capabilities, and lower barriers to adoption through education, consultation, and networking.
Administratively, this opportunity falls under the discretionary grant category and is listed under the health funding activity area, with CFDA number 93.310 (Trans-NIH Research Support). The posting date and creation date were both December 2, 2011. The original and current closing date listed for this FOA was February 15, 2013, and the archive date was March 18, 2013, meaning the competition is no longer active and the announcement has been archived. Cost sharing or matching was not required, which generally reduces the financial burden on applicant organizations and can broaden participation.
Eligibility was intentionally broad and included many types of U.S.-based organizations that could plausibly host and operate a regional core facility. Eligible applicants included public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), small businesses, for-profit organizations other than small businesses, and a wide range of government entities (state, county, city or township, special district governments, and independent school districts). The FOA also recognized and included tribal governments and tribal organizations, public housing authorities/Indian housing authorities, and other regionally oriented entities. Additional eligible applicants explicitly included Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. Taken together, the eligibility list reflects NIH interest in building metabolomics capacity in diverse settings and geographies, not just within major research universities.
For those seeking the original details, the announcement provided an NIH Grants Guide link (http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-11-016.html). The contact information included NIH Office of Extramural Research (OER) webmaster support for access or linking issues (FBOWebmaster@OD.NIH.GOV), which is typical for older archived announcements where applicants might need help retrieving the complete FOA text.
Overall, the RCMRC (U24) opportunity was structured to create regionally distributed metabolomics hubs that combine service delivery, early-stage project support, training, and outreach. The underlying idea was to make metabolomics more usable and more widely used in biomedical research by providing shared infrastructure and practical expertise, while also cultivating a community of trained researchers who can apply metabolomics effectively in biological and clinical contexts.
FAQs: Regional Comprehensive Metabolomics Resource Cores (RCMRC) (U24) - RFA-RM-11-016
What is the RCMRC (U24) funding opportunity?
The Regional Comprehensive Metabolomics Resource Cores (RCMRC) program (U24) under RFA-RM-11-016 is an NIH cooperative agreement intended to expand U.S. biomedical research capacity in metabolomics by supporting regional, shared-use resource centers.
What was NIH trying to fund through this opportunity?
NIH sought applications to establish regional metabolomics resource cores that could provide high-quality metabolomics capabilities to a broad range of investigators, including researchers who may not already have access to advanced metabolomics platforms, expertise, or standardized workflows.
What does it mean that this is a U24 cooperative agreement?
A U24 cooperative agreement generally involves a more active partnership with NIH program staff than a standard research grant. The intent is to support centers that operate in close coordination with NIH, often with expectations around milestone-driven progress, coordination across sites, and alignment with national program goals.
What is the overall goal of the RCMRC program?
The goal was to strengthen the overall metabolomics ecosystem by creating regional hubs that deliver comprehensive services, foster consistent practices, support training, and engage the broader research community.
What types of activities were RCMRC centers expected to provide?
The program scope emphasized multiple complementary functions, including operating as a technology service center, supporting pilot and feasibility projects, providing training activities, and conducting outreach activities.
What does "technology service center" mean in this FOA?
In this context, it means offering access to metabolomics instrumentation, analytical pipelines, and technical support so investigators can generate metabolomics data using dependable infrastructure and services that extend beyond a single lab or department.
Were pilot and feasibility projects included in the program scope?
Yes. The FOA explicitly supported pilot and feasibility projects, described as small, targeted awards intended to help researchers test ideas, generate preliminary data, and demonstrate how metabolomics can be useful for specific biomedical questions.
What types of training were expected under the RCMRC program?
Training was an integral component, reflecting NIH interest in building a skilled workforce able to design metabolomics studies properly, handle biospecimens appropriately, perform robust analytical chemistry and bioinformatics, and interpret results in biologically meaningful ways.
What outreach expectations were included?
Outreach activities were supported to encourage engagement with the broader research community, increase awareness of metabolomics capabilities, and lower barriers to adoption through education, consultation, and networking.
What research areas was the program meant to support?
The emphasis was on enabling biological and clinical research uses of metabolomics by building dependable infrastructure, services, and expertise that could be accessed broadly.
Who was this opportunity intended to benefit?
It was designed to benefit a broad range of investigators, including those who did not already have access to advanced metabolomics platforms, specialized expertise, or standardized metabolomics workflows.
What was the CFDA number and funding activity area for this opportunity?
The opportunity was listed under the health funding activity area and identified with CFDA number 93.310 (Trans-NIH Research Support).
Was cost sharing or matching required?
No. Cost sharing or matching was not required.
Is this funding opportunity still open?
No. The FOA is no longer active. The listed closing date was February 15, 2013, and the archive date was March 18, 2013.
When was the opportunity posted?
The posting date and creation date were both December 2, 2011.
What was the original and current closing date shown in the announcement?
The original and current closing date listed for this FOA was February 15, 2013.
What does it mean that the announcement is archived?
It means the competition is no longer active and the announcement has been formally archived, consistent with the archive date of March 18, 2013.
What types of organizations were eligible to apply?
Eligibility was broad and included U.S.-based public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), small businesses, for-profit organizations other than small businesses, and many government entities.
Which government entities were listed as eligible applicants?
The FOA included eligibility for state governments, county governments, city or township governments, special district governments, independent school districts, as well as tribal governments and tribal organizations.
Were U.S. territories or possessions included as eligible applicants?
Yes. The FOA explicitly included U.S. territories or possessions among eligible applicants.
Were minority-serving institutions included in the eligibility list?
Yes. The FOA explicitly included Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other regionally oriented entities.
Were faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations were explicitly listed among eligible applicants.
Were eligible federal agencies included as potential applicants?
Yes. Eligible federal agencies were explicitly included in the eligibility list.
Where could applicants find the original FOA text?
The announcement referenced the NIH Grants Guide link: http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-11-016.html
Who was listed as a contact for access or linking issues related to the announcement?
The contact provided was NIH Office of Extramural Research (OER) webmaster support, with the email address FBOWebmaster@OD.NIH.GOV.
What kind of grant category was this listed under?
Administratively, it was listed under the discretionary grant category.
What is the "regional" concept in this program?
The program aimed to create regional, shared-use hubs so metabolomics infrastructure, services, expertise, training, and outreach could be accessed beyond a single lab, department, or local institution.
How was NIH involvement expected to differ from a typical research grant?
Because it was a cooperative agreement, NIH program staff were expected to be more actively involved, with centers operating in coordination with NIH and aligning with broader national program goals, potentially including milestone-driven progress and cross-site coordination.
What was the practical impact NIH wanted these centers to have?
The centers were intended to make metabolomics more usable and more widely used in biomedical research by providing shared infrastructure and practical expertise, while also cultivating a community of researchers trained to apply metabolomics effectively in biological and clinical contexts.
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