Opportunity Information: Apply for RFA MH 11 081
Apply for RFA MH 11 081
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Reinvigorating HIV Prevention for Men who have Sex with Men (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Aug 17, 2010 and posted on Aug 17, 2010.
- Applicants must submit their applications by Jan 4, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Special district governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses City or township governments County governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Private institutions of higher education Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The National Institute of Mental Health (NIMH), part of the National Institutes of Health (NIH), offered this discretionary grant opportunity to support new research aimed at strengthening HIV prevention for men who have sex with men (MSM), particularly those at highest risk. The core goal is to encourage the development and early testing of innovative HIV prevention interventions that could realistically be expanded to a broad scale if they prove effective. NIMH is specifically interested in work that would help curb new HIV infections, reduce HIV-related illness and deaths, and address persistent disparities in HIV rates affecting MSM communities.
This opportunity used the NIH Exploratory/Developmental Grant mechanism (R21), which is generally designed for early-stage, high-potential studies that can generate strong preliminary evidence, refine intervention approaches, or open up promising new lines of research. The announcement also notes that it was part of a coordinated set of funding opportunities with essentially the same scientific focus but different grant mechanisms: a companion R01 announcement (RFA-MH-11-080) for larger, more comprehensive research projects, and a companion R34 announcement (RFA-MH-11-082) supporting clinical exploratory/developmental work that often focuses on intervention development and preparation for later-stage trials. In other words, the R21 pathway here was positioned as one option within a broader strategy to move HIV prevention intervention science forward, from early innovation through more extensive testing.
NIMH anticipated investing about $2,000,000 in fiscal year 2011 across this FOA and its companion announcements, with an expected total of roughly 4 to 6 awards. The listed award ceiling for this R21 opportunity was $200,000, signaling that projects were expected to be targeted and exploratory rather than large multi-site efficacy trials. The funding opportunity number was RFA-MH-11-081, and the program fell under CFDA 93.242 (Mental Health Research Grants). There was no cost sharing or matching requirement, meaning applicants were not required to provide non-federal funds to match the award.
Eligibility was intentionally broad and included many organization types across the public, private, nonprofit, and academic sectors. Eligible applicants included nonprofit organizations with or without 501(c)(3) status (other than institutions of higher education), public and private institutions of higher education, small businesses and other for-profit organizations (other than small businesses were also explicitly listed), and multiple levels of government (city/township, county, state). It also included public housing authorities/Indian housing authorities, special district governments, and tribal governments and organizations, including federally recognized Native American tribal governments as well as other tribal organizations. Additional eligible categories listed included faith-based and community-based organizations, historically underrepresented and mission-driven educational institutions such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities. The eligibility list also explicitly allowed non-U.S. entities (foreign organizations), regional organizations, and U.S. territories or possessions, reflecting an openness to strong proposals regardless of geography when appropriate to the research aims.
Key administrative details include a posted and creation date of August 17, 2010, with an original and current closing date of January 4, 2011, and an archive date of February 4, 2011. The full announcement was available through the NIH grants guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-11-081.html. For technical issues accessing or linking to the announcement, the contact listed was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, this FOA was designed to re-energize HIV prevention research focused on MSM by funding exploratory intervention studies with a clear path toward scalability and real-world impact, while emphasizing outcomes that matter at a population level: fewer new infections, better health outcomes for people at risk, and measurable progress in reducing inequities in HIV burden.
Frequently Asked Questions (FAQs)
What is the purpose of this grant opportunity?
This funding opportunity from the National Institute of Mental Health (NIMH), part of the National Institutes of Health (NIH), supports new research to strengthen HIV prevention for men who have sex with men (MSM), especially those at highest risk. The goal is to encourage innovative prevention interventions and early testing work that could realistically be scaled broadly if shown to be effective.
Which agency is offering the funding?
The opportunity is offered by the National Institute of Mental Health (NIMH) within the National Institutes of Health (NIH).
What is the funding opportunity number (FOA number)?
The FOA number is RFA-MH-11-081.
What grant mechanism does this opportunity use?
This announcement uses the NIH Exploratory/Developmental Grant mechanism (R21), which is intended for early-stage, high-potential studies that can produce preliminary evidence, refine intervention approaches, or open promising new research directions.
What kind of projects is NIMH looking to fund under this R21?
NIMH is interested in the development and early testing of innovative HIV prevention interventions for MSM, with emphasis on approaches that have a clear path to scalability and real-world impact if they prove effective.
What outcomes is this program trying to influence?
The FOA emphasizes population-relevant outcomes, including curbing new HIV infections, reducing HIV-related illness and deaths, and addressing persistent disparities in HIV rates affecting MSM communities.
Is this opportunity part of other related NIH announcements?
Yes. This R21 FOA was part of a coordinated set of opportunities with essentially the same scientific focus but different mechanisms. Companion announcements included an R01 (RFA-MH-11-080) for larger, more comprehensive projects and an R34 (RFA-MH-11-082) supporting clinical exploratory/developmental work often focused on intervention development and preparation for later-stage trials.
How many awards were expected?
NIMH expected approximately 4 to 6 awards across this FOA and its companion announcements.
How much funding did NIMH anticipate investing?
NIMH anticipated investing about $2,000,000 in fiscal year 2011 across this FOA and its companion announcements.
What was the award ceiling for this R21 opportunity?
The listed award ceiling for this R21 opportunity was $200,000, indicating projects were expected to be targeted and exploratory rather than large, multi-site efficacy trials.
Is cost sharing or matching required?
No. There was no cost sharing or matching requirement, meaning applicants were not required to provide non-federal funds to match the award.
What is the CFDA number associated with this program?
The program falls under CFDA 93.242 (Mental Health Research Grants).
Who was eligible to apply?
Eligibility was broad and included a wide range of organizations across public, private, nonprofit, academic, and governmental sectors. Eligible applicants included nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education), public and private institutions of higher education, small businesses, other for-profit organizations, and multiple levels of government (city/township, county, and state). Additional eligible categories included public housing authorities/Indian housing authorities, special district governments, tribal governments and organizations (including federally recognized Native American tribal governments and other tribal organizations), faith-based and community-based organizations, and mission-driven educational institutions such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities.
Were non-U.S. entities allowed to apply?
Yes. The eligibility list explicitly allowed non-U.S. entities (foreign organizations), regional organizations, and U.S. territories or possessions, reflecting openness to strong proposals regardless of geography when appropriate to the research aims.
When was the opportunity posted?
The posted and creation date was August 17, 2010.
What was the application closing date?
The original and current closing date listed was January 4, 2011.
When was the opportunity archived?
The archive date was February 4, 2011.
Where can the full announcement be found?
The full announcement was available through the NIH grants guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-11-081.html.
Who should be contacted for technical issues accessing or linking to the announcement?
For technical issues accessing or linking to the announcement, the listed contact was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
How does the R21 fit within the broader strategy described in the announcement?
The R21 mechanism was positioned as one option within a broader, coordinated approach to move HIV prevention intervention science forward, ranging from early innovation and preliminary testing (R21) to more extensive research projects (R01), alongside clinical exploratory/developmental work often focused on intervention development and readiness for later-stage trials (R34).
Is this funding intended for large multi-site efficacy trials?
Based on the stated $200,000 award ceiling and the R21 exploratory/developmental focus, projects were expected to be targeted and exploratory rather than large multi-site efficacy trials.
Browse more opportunities from the same category: Health
Next opportunity: Reinvigorating HIV Prevention for Men who have Sex with Men (R34)
Previous opportunity: Reinvigorating HIV Prevention for Men who have Sex with Men (R01)
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