Opportunity Information: Apply for PA 14 219

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
  • This funding opportunity was created on May 13, 2014 and posted on May 12, 2014.
  • Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $800,000.00 in funding.
  • Eligible applicants include: Small businesses.
  • Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
Apply for PA 14 219

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Opportunity Summary:

The grant opportunity titled "Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44)" (Funding Opportunity Number PA-14-219) is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) funding announcement designed for small businesses that are ready to keep pushing an already-funded SBIR project beyond the original Phase II work. In practical terms, it is aimed at companies that previously received an SBIR Phase II award and now need additional support to continue developing a more advanced, often harder-to-finish product or program related to brain and behavior. The emphasis is on moving promising innovations closer to real-world use by extending the development timeline for technologies that typically require more time, testing, and refinement than a standard Phase II period allows.

The focus area covers tools and interventions connected to mental health and mental disorders, reflected in the activity category of Health and the CFDA listing of 93.242 (Mental Health Research Grants). The FOA highlights three major kinds of work it wants to support: complex instrumentation (for example, sophisticated devices or systems used in neuroscience or behavioral science research), clinical research tools (such as assessment platforms, measurement technologies, or other toolsets that enable or improve clinical research), and behavioral interventions (structured programs or methods intended to change behavior, improve outcomes, or treat aspects of mental disorders). While the announcement does not list specific disorders or technologies in the provided text, the framing makes clear that the target is development work that is still in progress and needs additional funding to reach a more complete, usable, and potentially market-ready stage.

A key feature is that it is a competing renewal mechanism for Phase IIB under the SBIR program, using the R44 grant mechanism. "Competing renewal" means this is not an automatic extension; applicants must submit a new application that competes for funding and must justify why additional Phase IIB support is needed and how it will advance the technology beyond what the earlier Phase II achieved. The intent is to continue the development process rather than to start a new idea from scratch, so the underlying expectation is that applicants will build directly on prior SBIR Phase II outcomes, using that progress as the foundation for the next set of development milestones.

From an administrative standpoint, this opportunity is a discretionary grant program with no cost sharing or matching requirement, which means applicants generally are not required to bring matching funds as a condition of the award (though small businesses often still leverage private capital or partnerships to strengthen commercialization plans). The listed award ceiling is $800,000, indicating the maximum funding level anticipated per award under this announcement as summarized in the source data. The posting date was May 12, 2014, with a creation date of May 13, 2014. The original closing date and current closing date were both May 7, 2017, and the opportunity was archived on June 7, 2017, meaning it is no longer open for new submissions under that specific announcement, but it remains useful as a reference point for similar NIH SBIR Phase IIB renewal opportunities.

Eligibility is limited to small businesses, consistent with the SBIR program. The announcement also makes clear that non-U.S. entities (foreign institutions) are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible to apply. At the same time, it notes that foreign components, as defined in the NIH Grants Policy Statement, may be allowed, which typically means certain parts of the work can be conducted outside the U.S. if they meet NIH policy requirements and are well-justified, even though the applicant organization itself must be eligible as a U.S. small business.

For applicants or readers looking for the full official announcement details, NIH provided an additional information link at http://grants.nih.gov/grants/guide/pa-files/PA-14-219.html. For technical issues accessing the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, including support for both access problems and linking issues.

FAQs: Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44) (PA-14-219)

What is the purpose of this grant opportunity?

This funding announcement supports competing renewal awards under the NIH SBIR program for projects that already received an SBIR Phase II award and need additional Phase IIB support to keep developing the same technology, tool, or intervention beyond the original Phase II scope. The main goal is to move promising brain and behavior innovations closer to real-world use by extending development time for work that typically requires more testing, refinement, and advanced development than a standard Phase II period allows.

What is the official title and funding opportunity number?

The opportunity is titled "Renewal Awards of SBIR Phase IIB Grants for Brain and Behavior Tools (R44)." The Funding Opportunity Number is PA-14-219.

Which agency runs this opportunity?

This is a National Institutes of Health (NIH) funding announcement under the Small Business Innovation Research (SBIR) program.

What grant mechanism/activity code does it use?

The announcement uses the R44 grant mechanism, described as an SBIR Phase IIB competing renewal mechanism.

What does "competing renewal" mean in this context?

"Competing renewal" means the award is not an automatic extension of prior SBIR funding. Applicants must submit a new application that competes for funding and must justify why additional Phase IIB support is needed and how it will advance the technology beyond what was achieved during the earlier Phase II award.

Is this intended for new ideas or existing SBIR projects?

It is intended to continue development of an already-funded SBIR project, not to start a new concept from scratch. The expectation is that the proposed Phase IIB renewal work builds directly on prior SBIR Phase II outcomes and uses that progress as the foundation for the next development milestones.

What types of projects does the announcement emphasize?

The FOA highlights three major categories: complex instrumentation (such as sophisticated devices or systems used in neuroscience or behavioral science research), clinical research tools (including assessment platforms, measurement technologies, or other toolsets that enable or improve clinical research), and behavioral interventions (structured programs or methods intended to change behavior, improve outcomes, or treat aspects of mental disorders).

What broader field or topic area is this funding tied to?

The focus is on tools and interventions connected to mental health and mental disorders, reflected in the activity category of Health and the CFDA listing of 93.242 (Mental Health Research Grants).

Does the provided information list specific disorders or technologies that must be addressed?

No. The provided text does not list specific disorders or required technologies. It frames the target as in-progress development work related to brain and behavior tools and interventions that needs additional funding to reach a more complete and usable stage.

Who is eligible to apply?

Eligibility is limited to small businesses, consistent with the SBIR program. The applicant organization must be eligible as a small business.

Are foreign (non-U.S.) organizations eligible to apply?

No. Non-U.S. entities (foreign institutions) are not eligible to apply under this announcement.

Can a U.S. organization include a non-U.S. component?

The announcement states that non-U.S. components of U.S. organizations are not eligible to apply. However, it also notes that foreign components, as defined in the NIH Grants Policy Statement, may be allowed. This typically means certain parts of the work may be conducted outside the U.S. if allowed under NIH policy and well-justified, even though the applicant organization itself must be an eligible U.S. small business.

Is cost sharing or matching required?

No. This is described as a discretionary grant program with no cost sharing or matching requirement, meaning applicants are generally not required to provide matching funds as a condition of the award.

What is the maximum award amount mentioned?

The listed award ceiling is $800,000, which is the maximum funding level anticipated per award under this announcement as summarized in the provided information.

When was this opportunity posted and when did it close?

The posting date was May 12, 2014, and the creation date was May 13, 2014. The original closing date and current closing date were both May 7, 2017.

Is this funding opportunity still open?

No. The opportunity was archived on June 7, 2017, which indicates it is no longer open for new submissions under that specific announcement.

Why might this archived announcement still matter to applicants?

Even though it is no longer open, it can still be useful as a reference point for similar NIH SBIR Phase IIB renewal opportunities, especially for understanding the general intent, project types emphasized, and basic eligibility boundaries described in the announcement.

Where can applicants find the full official announcement?

NIH provided an additional information link to the full announcement at: http://grants.nih.gov/grants/guide/pa-files/PA-14-219.html

Who can be contacted for technical issues accessing the announcement?

For technical issues such as access problems or linking issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

What is the main development outcome NIH appears to be encouraging?

Based on the provided description, the emphasis is on extending development so that promising innovations in brain and behavior can move closer to practical use, including reaching a more complete, usable, and potentially market-ready stage.

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