Opportunity Information: Apply for PA 15 036
Apply for PA 15 036
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Research Aimed at Novel Behavioral Targets to Improve Adolescent Substance Abuse Treatment and Prevention Interventions (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.399 Cancer Control.
- This funding opportunity was created on Nov 19, 2014 and posted on Nov 18, 2014.
- Applicants must submit their applications by Jan 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses For profit organizations other than small businesses Independent school districts City or township governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Special district governments Native American tribal organizations (other than Federally recognized tribal governments) State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The grant opportunity "Research Aimed at Novel Behavioral Targets to Improve Adolescent Substance Abuse Treatment and Prevention Interventions (R01)" (Funding Opportunity Number PA 15 036) is a National Institutes of Health (NIH) research grant announcement created under the broader, trans-NIH initiative called Collaborative Research on Addiction at NIH (CRAN). Its central purpose is to support research that strengthens how adolescent substance use treatment and prevention programs are designed by identifying, testing, and refining specific behavioral and neurobehavioral targets that can be directly influenced by interventions. Rather than only evaluating whether a program works in a general sense, the FOA emphasizes understanding the underlying mechanisms that drive substance use risk and recovery in adolescents and using that knowledge to build more precise and effective interventions.
A key theme of this FOA is the development or improvement of intervention components (including modules that can be added onto existing treatment or prevention programs) that deliberately focus on modulating measurable behavioral processes linked to adolescent substance use. Examples named in the announcement include impulsivity, risk-taking propensity, sensation and novelty seeking, distress tolerance, delay discounting, self-regulation, and stress reactivity. In practical terms, projects might involve designing or adapting therapeutic strategies to specifically reduce maladaptive impulsive decision-making, improve emotion regulation under stress, increase tolerance for distress without turning to substances, or shift reward-related decision processes that contribute to risky use. The overall intent is to move the field toward interventions that are more targeted, more mechanistically informed, and easier to refine over time because they are built around clearly defined change targets.
Another major priority is linking behavioral targets to brain-based mechanisms. The FOA explicitly encourages applicants to build theoretical and empirical bridges between neural circuitry and the effects of treatment or prevention. That includes studying how interventions change behavior by altering neurobehavioral processes and how those neural and behavioral changes relate to meaningful outcomes such as reduced substance use, fewer relapses, and improved functioning. Importantly, the announcement is not simply calling for neuroscience for its own sake; it frames neural circuitry as a tool to better understand why interventions succeed or fail, how to optimize them, and how to tailor them to adolescents in ways that translate into real-world reductions in morbidity and mortality associated with substance use.
Administratively, this opportunity uses the NIH R01 research project grant mechanism and is categorized as a discretionary grant. It is tied to several CFDA program areas, including Alcohol Research Programs (93.273), Drug Abuse and Addiction Research Programs (93.279), and Cancer Control (93.399), reflecting NIH's broad interest in addiction research and its downstream health consequences. The FOA states that cost sharing or matching is not required, which is typical for many NIH research project grants.
Eligibility is broad and includes a wide range of U.S.-based organizations and governments. Eligible applicants listed include small businesses, for-profit entities (including those other than small businesses), nonprofit organizations with or without 501(c)(3) status, public and private institutions of higher education, independent school districts, and multiple levels of government (city/township, county, state, and special district governments), as well as public housing authorities and tribal governments or tribal organizations. The FOA also highlights that various mission-driven institution types and community-focused entities can apply, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and other designated minority-serving institutions, along with faith-based and community-based organizations and eligible federal agencies. Foreign organizations and foreign institutions are not eligible to apply directly, and non-U.S. components of U.S. organizations are not eligible; however, foreign components as defined by NIH policy are allowed, meaning certain international collaborations may be permissible when structured as components within an otherwise eligible application.
In terms of timing, the opportunity was posted on November 18, 2014, created on November 19, 2014, and had an original and final listed closing date of January 7, 2018, with an archive date of February 7, 2018. The administering agency is NIH, and the full announcement was made available through the NIH grants guide (the FOA link is provided in the source). For technical access issues, the contact provided is the NIH Office of Extramural Research (OER) webmaster via email.
Overall, PA 15 036 supports mechanism-focused adolescent substance use research that goes beyond broad program evaluation and instead aims to produce clearer, testable intervention targets and more efficient treatment and prevention strategies. The emphasis on behavioral targets, their modifiability through intervention components, and the encouraged integration with neural circuitry is meant to accelerate development of interventions that are not only effective, but also scientifically explainable and systematically improvable, ultimately reducing the health and social burdens associated with adolescent substance use.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled "Research Aimed at Novel Behavioral Targets to Improve Adolescent Substance Abuse Treatment and Prevention Interventions (R01)."
What is the Funding Opportunity Number (FON) for this announcement?
The Funding Opportunity Number is PA 15 036.
Which agency is administering this grant?
The administering agency is the National Institutes of Health (NIH).
What type of award mechanism does this opportunity use?
This funding opportunity uses the NIH R01 Research Project Grant mechanism.
Is this considered a discretionary grant?
Yes. The opportunity is categorized as a discretionary grant.
What is the main purpose of this FOA?
The central purpose is to support research that improves how adolescent substance use treatment and prevention programs are designed by identifying, testing, and refining specific behavioral and neurobehavioral targets that can be directly influenced by interventions.
How is this FOA different from general program evaluation studies?
Rather than only asking whether a program works overall, the FOA emphasizes understanding the underlying mechanisms that drive substance use risk and recovery in adolescents and using that mechanistic knowledge to build more precise, targeted, and systematically improvable interventions.
What does the FOA mean by "behavioral targets"?
In this announcement, behavioral targets are measurable behavioral or neurobehavioral processes linked to adolescent substance use that can be modulated through intervention components. The idea is to focus interventions on specific change targets that can be tested and refined over time.
What examples of behavioral targets are specifically named in the announcement?
Examples named include impulsivity, risk-taking propensity, sensation and novelty seeking, distress tolerance, delay discounting, self-regulation, and stress reactivity.
What kinds of projects does the FOA encourage?
The FOA encourages projects that develop, test, refine, or improve intervention components (including add-on modules to existing treatment or prevention programs) that deliberately focus on modulating measurable behavioral processes associated with adolescent substance use.
Does the FOA support adding modules onto existing interventions?
Yes. The announcement explicitly notes intervention components, including modules that can be added onto existing treatment or prevention programs.
Does this opportunity prioritize research connected to brain-based mechanisms?
Yes. A major priority is linking behavioral targets to brain-based mechanisms by building theoretical and empirical bridges between neural circuitry and the effects of treatment or prevention.
Is the FOA calling for neuroscience research for its own sake?
No. The announcement frames neural circuitry as a tool to understand why interventions succeed or fail, how to optimize them, and how to tailor them to adolescents in ways that translate into meaningful real-world outcomes.
What types of outcomes does the FOA point to as meaningful?
The FOA references outcomes such as reduced substance use, fewer relapses, and improved functioning, and it emphasizes reducing morbidity and mortality associated with substance use.
What broader NIH initiative is this FOA associated with?
This FOA was created under the broader, trans-NIH initiative called Collaborative Research on Addiction at NIH (CRAN).
Which CFDA program areas are associated with this opportunity?
The opportunity is tied to CFDA program areas including Alcohol Research Programs (93.273), Drug Abuse and Addiction Research Programs (93.279), and Cancer Control (93.399).
Is cost sharing or matching required?
No. The FOA states that cost sharing or matching is not required.
Who is eligible to apply?
Eligibility is broad and includes many U.S.-based organizations and governments, including small businesses; for-profit entities (including those other than small businesses); nonprofit organizations with or without 501(c)(3) status; public and private institutions of higher education; and independent school districts. Multiple levels of government are also eligible, including city/township, county, state, and special district governments, as well as public housing authorities and tribal governments or tribal organizations.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The FOA highlights that mission-driven institution types and community-focused entities can apply, including HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and other designated minority-serving institutions.
Are faith-based and community-based organizations eligible?
Yes. The FOA lists faith-based and community-based organizations among eligible applicants.
Are eligible federal agencies allowed to apply?
Yes. Eligible federal agencies are included among the eligible applicants listed in the FOA description provided.
Can foreign organizations or foreign institutions apply directly?
No. Foreign organizations and foreign institutions are not eligible to apply directly.
Are non-U.S. components of U.S. organizations eligible?
No. Non-U.S. components of U.S. organizations are not eligible.
Are any international collaborations allowed at all?
Yes, in a limited way. The FOA indicates that foreign components (as defined by NIH policy) are allowed, meaning certain international collaborations may be permissible when structured as components within an otherwise eligible application.
When was this opportunity posted and created?
It was posted on November 18, 2014, and created on November 19, 2014.
What was the closing date for this FOA?
The original and final listed closing date was January 7, 2018.
When was the opportunity archived?
The archive date was February 7, 2018.
Where was the full announcement made available?
The full announcement was made available through the NIH grants guide (the FOA link is referenced in the source information).
Who should be contacted for technical access issues with the announcement?
For technical access issues, the contact provided is the NIH Office of Extramural Research (OER) webmaster via email.
What is the overall research focus area supported by PA 15 036?
PA 15 036 supports mechanism-focused adolescent substance use research that aims to produce clearer, testable intervention targets and more efficient treatment and prevention strategies, with an emphasis on behavioral targets, their modifiability through intervention components, and encouraged integration with neural circuitry.
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| Funding Opportunity |
|---|
| Research Aimed at Novel Behavioral Targets to Improve Adolescent Substance Abuse Treatment and Prevention Interventions (R34) Apply for PA 15 035 Funding Number: PA 15 035 Agency: National Institutes of Health Category: Education Health Funding Amount: $450,000 |
| Cancer Detection, Diagnosis, and Treatment Technologies for Global Health (UH2/UH3) Apply for RFA CA 15 001 Funding Number: RFA CA 15 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,000,000 |
| Exploratory Grant Award to Promote Workforce Diversity in Basic Cancer Research (R21) Apply for PAR 15 053 Funding Number: PAR 15 053 Agency: National Institutes of Health Category: Education Health Funding Amount: $275,000 |
| NCI Mentored Clinical Scientist Research Career Development Award to Promote Diversity (K08) Apply for PAR 15 060 Funding Number: PAR 15 060 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NCI Mentored Patient Oriented Research Career Development Award to Promote Diversity (K23) Apply for PAR 15 062 Funding Number: PAR 15 062 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NCI Transition Career Development Award to Promote Diversity (K22) Apply for PAR 15 063 Funding Number: PAR 15 063 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NCI Mentored Research Scientist Development Award to Promote Diversity (K01) Apply for PAR 15 064 Funding Number: PAR 15 064 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The NCI Transition Career Development Award (K22) Apply for PAR 15 056 Funding Number: PAR 15 056 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Building on High Impact Basic Neurobiology Through Assay Development Advancing Tools for Therapeutic Discovery (R01) Apply for PAR 15 066 Funding Number: PAR 15 066 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Academic Industrial Partnerships for Translation of Technologies for Cancer Diagnosis and Treatment (R01) Apply for PAR 15 075 Funding Number: PAR 15 075 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Integration of Infectious Diseases and Substance Abuse Intervention Services for Individuals Living with HIV (R01) Apply for RFA DA 15 013 Funding Number: RFA DA 15 013 Agency: National Institutes of Health Category: Education Health Funding Amount: $3,000,000 |
| Cutting Edge Basic Research Awards (CEBRA) (R21) Apply for PAR 15 079 Funding Number: PAR 15 079 Agency: National Institutes of Health Category: Education Health Funding Amount: $125,000 |
| Innovative Molecular Analysis Technologies for Cancer Research (R21) Apply for RFA CA 15 002 Funding Number: RFA CA 15 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $2,000,000 |
| Innovative Technologies for Cancer Relevant Biospecimen Science (R21) Apply for RFA CA 15 004 Funding Number: RFA CA 15 004 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Advanced Development and Validation of Emerging Molecular Analysis Technologies for Cancer Research (R33) Apply for RFA CA 15 003 Funding Number: RFA CA 15 003 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Advanced Development and Validation of Emerging Technologies for Cancer Relevant Biospecimen Science (R33) Apply for RFA CA 15 005 Funding Number: RFA CA 15 005 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Drug Abuse Prevention Intervention Research (R21) Apply for PA 15 080 Funding Number: PA 15 080 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Drug Abuse Prevention Intervention Research (R03) Apply for PA 15 081 Funding Number: PA 15 081 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Drug Abuse Prevention Intervention Research (R01) Apply for PA 15 082 Funding Number: PA 15 082 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| BRAIN Initiative Development, Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR) (R41/R42) Apply for PAR 15 090 Funding Number: PAR 15 090 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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