Opportunity Information: Apply for NNJ12ZSA002N

  • The NASA Johnson Space Center in the health sector is offering a public funding opportunity titled "RESEARCH AND TECHNOLOGY DEVELOPMENT TO SUPPORT CREW HEALTH AND PERFORMANCE IN SPACE EXPLORATION MISSIONS" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 43.003 Exploration.
  • This funding opportunity was created on Jul 17, 2012 and posted on Jul 17, 2012.
  • Applicants must submit their applications by NRA not available yet.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $400,000.00 in funding.
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
  • Participation is open to all categories of organizations, foreign and domestic, including industry, educational institutions, nonprofit organizations, NASA centers and other Government Agencies.
Apply for NNJ12ZSA002N

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Opportunity Summary:

This funding opportunity is a NASA Research Announcement (NRA) issued by NASA's Johnson Space Center, focused on research and technology development that improves astronaut health and human performance during space exploration missions. The announcement is labeled NNJ12ZSA002N and is jointly tied to two funding/evaluation tracks: one managed by NASA in support of its Human Research Program (HRP), and a separate one managed by the National Space Biomedical Research Institute (NSBRI). While the solicitation is presented together, proposals aimed at NASA topic areas and proposals aimed at NSBRI topic areas must be submitted as separate applications, will be reviewed independently, and can lead to separate awards.

On the NASA side, the solicitation emphasizes several specific human health and performance risks relevant to exploration missions. These include sensorimotor impairment and space motion sickness (how crews adapt to altered gravity and how that affects balance, orientation, and operational capability), epidemiological evidence of spaceflight-induced cardiovascular disease (population-level or crew cohort data that could clarify long-term cardiovascular impacts), and computational models of cephalad fluid shifts (modeling the headward movement of fluids in microgravity that is linked to multiple physiological changes). NASA also highlights interest in characterizing the "spaceflight biochemical profile" (biomarkers and physiological signatures associated with spaceflight stressors), methods for maintaining and regulating team function and performance over extended durations (the behavioral and organizational challenges of long missions), and the development of safety and efficiency metrics for human automation systems (ways to measure and improve the interaction between astronauts and automated/semiautonomous systems). In addition to these named areas, NASA explicitly invites short-term investigations or technologies that propose innovative approaches addressing any of the defined risks listed in the Human Research Program Integrated Research Plan, referenced through the Human Research Roadmap website.

On the NSBRI side, the research areas are broader but aligned with similar space biomedical priorities. NSBRI solicits proposals related to cardiovascular alterations, human factors and performance, musculoskeletal alterations, neurobehavioral and psychosocial factors, sensorimotor adaptation, and smart medical systems and technology. Taken together, the NASA and NSBRI topics signal a strong preference for work that either reduces known exploration risks, improves crew readiness and operational performance, or advances monitoring and countermeasure capabilities that can be used in constrained, remote mission environments.

The submission process is two-step. Step 1 proposals (often a shorter preliminary proposal) are due September 4, 2012 at 5:00 PM Eastern Time. Applicants invited to proceed then submit Step 2 proposals (the more complete proposal package) by December 3, 2012 at 5:00 PM Eastern Time. Proposals must be submitted electronically by an authorized organizational official, not informally by an individual investigator. Step 1 submissions can be made through NSPIRES (NASA's proposal system) or through Grants.gov, but organizations intending to apply must be registered in NSPIRES and must identify their authorized organizational representative(s). Because NSPIRES and Grants.gov also impose account and profile requirements for principal investigators and key personnel (such as co-investigators), the announcement advises applicants to begin registrations and system familiarization well before the deadline to avoid last-minute administrative issues.

Eligibility is broad and essentially unrestricted, covering domestic and foreign entities across many organization types, including universities, companies, nonprofits, NASA centers, and other government agencies. The opportunity is categorized as discretionary, uses a grant instrument, and falls under CFDA 43.003 (Exploration). The listing indicates no cost sharing or matching requirement. An award ceiling of $400,000 is stated, implying that projects are expected to be scoped within that upper limit, though the full solicitation would typically clarify period of performance, allowable costs, and whether the ceiling applies per year or per project.

Administratively, this announcement is treated as a broad agency announcement under FAR 6.102(d)(2), which generally means NASA is seeking innovative scientific and technical approaches rather than a single narrowly specified deliverable. The notice also states that NASA and/or NSBRI reserve the right to choose the appropriate award instrument for selected proposals, even if the opportunity is posted through standard public portals. The full solicitation document was expected to be available around July 30, 2012 through the NASA Research Opportunities/NSPIRES site, and applicants with access issues or proposal questions are directed to the listed contacts (including Rochelle Nicole Overstreet, LaToy J. Jones, and NAIS Support).

Frequently Asked Questions (FAQs)

1. What is this funding opportunity?

This opportunity is a NASA Research Announcement (NRA) issued by NASA's Johnson Space Center for research and technology development that improves astronaut health and human performance during space exploration missions. The announcement identifier is NNJ12ZSA002N.

2. Who is issuing and managing the solicitation?

The solicitation is presented as a single announcement, but it is jointly tied to two separate funding/evaluation tracks: (1) a NASA-managed track in support of NASA's Human Research Program (HRP) and (2) a separate track managed by the National Space Biomedical Research Institute (NSBRI).

3. Are the NASA and NSBRI tracks the same application?

No. Even though the topics are presented together, proposals aimed at NASA topic areas and proposals aimed at NSBRI topic areas must be submitted as separate applications. They will be reviewed independently and can result in separate awards.

4. What kinds of projects is NASA looking for under the HRP track?

NASA emphasizes research and technology development addressing astronaut health and human performance risks relevant to exploration missions, including:

  • Sensorimotor impairment and space motion sickness (adaptation to altered gravity and impacts on balance, orientation, and operational capability)
  • Epidemiological evidence of spaceflight-induced cardiovascular disease (crew cohort or population-level data clarifying long-term cardiovascular impacts)
  • Computational models of cephalad fluid shifts (modeling headward fluid movement in microgravity and related physiological changes)
  • Characterizing the "spaceflight biochemical profile" (biomarkers and physiological signatures associated with spaceflight stressors)
  • Maintaining and regulating team function and performance over extended durations (behavioral and organizational challenges of long missions)
  • Developing safety and efficiency metrics for human automation systems (measures to improve astronaut interaction with automated/semiautonomous systems)

5. Can NASA proposals address topics beyond the named focus areas?

Yes. NASA explicitly invites short-term investigations or technologies that propose innovative approaches addressing any of the defined risks listed in the Human Research Program Integrated Research Plan, referenced through the Human Research Roadmap website.

6. What kinds of projects is NSBRI looking for?

NSBRI solicits proposals in broader space biomedical areas aligned with exploration needs, including:

  • Cardiovascular alterations
  • Human factors and performance
  • Musculoskeletal alterations
  • Neurobehavioral and psychosocial factors
  • Sensorimotor adaptation
  • Smart medical systems and technology

7. What overall themes do the NASA and NSBRI topics suggest?

Taken together, the topics indicate a strong preference for work that reduces known exploration risks, improves crew readiness and operational performance, or advances monitoring and countermeasure capabilities suitable for constrained, remote mission environments.

8. What is the proposal submission process?

The process is two-step:

  • Step 1 proposals are due September 4, 2012 at 5:00 PM Eastern Time.
  • Step 2 proposals (submitted only if invited after Step 1) are due December 3, 2012 at 5:00 PM Eastern Time.

9. Do all applicants submit Step 2 proposals?

No. Step 2 proposals are submitted only by applicants who are invited to proceed after Step 1 review.

10. How must proposals be submitted?

Proposals must be submitted electronically by an authorized organizational official. The announcement indicates that submissions are not made informally by an individual investigator.

11. Where can Step 1 proposals be submitted?

Step 1 submissions can be made through NSPIRES (NASA's proposal system) or through Grants.gov.

12. Is NSPIRES registration required even if using Grants.gov?

Yes. Organizations intending to apply must be registered in NSPIRES and must identify their authorized organizational representative(s), even though Step 1 may be submitted via NSPIRES or Grants.gov.

13. Do principal investigators and key personnel need accounts or profiles?

Yes. The announcement notes that NSPIRES and Grants.gov impose account and profile requirements for principal investigators and key personnel (including co-investigators). Applicants are advised to start registrations and system familiarization well before the deadline to avoid administrative issues.

14. Who is eligible to apply?

Eligibility is broad and essentially unrestricted. The announcement includes domestic and foreign entities across many organization types, including universities, companies, nonprofits, NASA centers, and other government agencies.

15. What funding instrument is expected?

The opportunity is categorized as discretionary and uses a grant instrument. The notice also states that NASA and/or NSBRI reserve the right to choose the appropriate award instrument for selected proposals.

16. What is the CFDA number for this opportunity?

The opportunity is listed under CFDA 43.003 (Exploration).

17. Is cost sharing or matching required?

No. The listing indicates there is no cost sharing or matching requirement.

18. What is the maximum award amount?

An award ceiling of $400,000 is stated. This implies projects should be scoped within that upper limit, though the full solicitation would typically clarify additional details (such as period of performance and whether the ceiling applies per year or per project).

19. What does it mean that this is treated as a broad agency announcement?

Administratively, the announcement is treated as a broad agency announcement under FAR 6.102(d)(2), which generally indicates NASA is seeking innovative scientific and technical approaches rather than a single narrowly specified deliverable.

20. When was the full solicitation document expected to be available, and where?

The full solicitation document was expected to be available around July 30, 2012 through the NASA Research Opportunities/NSPIRES site.

21. Who are the listed points of contact for access issues or proposal questions?

Applicants with access issues or proposal questions are directed to the listed contacts, including Rochelle Nicole Overstreet, LaToy J. Jones, and NAIS Support.

22. If an applicant wants to target both NASA and NSBRI topics, what should they do?

They should prepare and submit separate applications: one aligned to NASA topic areas (NASA HRP track) and another aligned to NSBRI topic areas (NSBRI track). These will be reviewed independently and may lead to separate awards.

23. What practical administrative step is emphasized to avoid problems near the deadline?

The announcement advises starting registrations and becoming familiar with NSPIRES and/or Grants.gov well in advance, because organizations must identify authorized organizational representatives and because principal investigators and key personnel must meet system account/profile requirements.

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