Opportunity Information: Apply for RFA HS 11 005

  • The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "Research Centers for Excellence in Clinical Preventive Services (P01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226 Research on Healthcare Costs, Quality and Outcomes.
  • This funding opportunity was created on Mar 11, 2011 and posted on Mar 11, 2011.
  • Applicants must submit their applications by May 23, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments State governments Public and State controlled institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Eligible Agencies of the Federal Government Indian/Native American Tribal Governments (Other than Federally Recognized).
Apply for RFA HS 11 005

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Opportunity Summary:

The Research Centers for Excellence in Clinical Preventive Services (P01) funding opportunity (Funding Opportunity Number RFA-HS-11-005) was issued by the Agency for Healthcare Research and Quality (AHRQ) to support the creation of research centers that can drive forward practical, high-impact research on clinical preventive services. It uses the Research Program Project Grant (P01) mechanism, which is designed for coordinated, multi-project programs where several related research projects and shared cores work together under one integrated center structure. The central idea is to fund tightly connected research that is more powerful as a package than as a set of separate studies, with an emphasis on synergy, shared resources, and a common theme.

The program is aimed at strengthening how evidence-based clinical preventive services are delivered through the formal health care system, with primary care positioned as a major point of leverage. Rather than funding prevention work in the broad public health sense, this initiative focuses on what happens inside health care settings: how preventive services are selected, implemented, delivered safely, and made routine in real clinical workflows. AHRQ frames this as complementary to other Federal prevention and public health investments by concentrating on the health care system's direct role in improving population health, improving the effectiveness and efficiency of care, enhancing patient safety, and improving patient experience. A key motivation behind the initiative is to accelerate progress aligned with the emerging National Prevention Strategy at the time of the announcement, by producing actionable evidence on how to implement preventive services well, not simply proving that they work.

Applicants were asked to build a Research Center for Excellence organized around one of three programmatic focus areas. The first is patient safety, emphasizing research that ensures preventive services are delivered in ways that reduce harm, prevent errors, and support safe decision-making in clinical practice. The second is health equity, emphasizing research that improves the reach, quality, and outcomes of preventive services for populations that experience disparities, including work that addresses inequities in access, uptake, and benefits from prevention. The third is health care system implementation, emphasizing research on the practical realities of adopting and sustaining evidence-based preventive services across health systems, including workflow integration, organizational change, quality improvement approaches, and strategies for reliable delivery at scale. Across all three tracks, the expectation is that the center's projects collectively form a coherent, multidisciplinary program capable of producing generalizable knowledge and usable implementation strategies.

From an eligibility standpoint, the opportunity was broadly open to a range of public-sector and academic institutions and certain tribal and governmental entities. Eligible applicants included city or township governments, county governments, state governments, public and state-controlled institutions of higher education, federally recognized Native American tribal governments, and other Native American tribal organizations. The announcement also notes that other eligible applicants include eligible agencies of the Federal Government, as well as Indian/Native American tribal governments other than federally recognized entities, reflecting AHRQ's intent to enable participation by a wide range of organizations involved in health care delivery, research, and policy. The funding activity category is Health, and the CFDA listing associated with the opportunity is 93.226 (Research on Healthcare Costs, Quality and Outcomes). There was no cost sharing or matching requirement, which typically lowers barriers to participation and allows centers to focus on building the strongest scientific program rather than assembling non-federal match.

The timeline for the opportunity reflects its status as an archived program announcement. It was posted on March 11, 2011, with an original and current closing date of May 23, 2011, and an archive date of June 23, 2011. As a result, it represents a specific historical competition rather than an open, ongoing call. The full announcement was made available through an NIH grants webpage link, and technical access questions were directed to the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.

Overall, this FOA sought to build a small number of strong, coordinated research centers capable of producing innovative and targeted evidence that helps the health care system deliver clinical preventive services more safely, more equitably, and more effectively in real-world practice. The emphasis was not only on generating new findings, but on structuring that work in a center model where multiple related projects reinforce each other, share methods and resources, and collectively push prevention implementation forward in ways that improve health outcomes and patient experience nationwide.

Frequently Asked Questions (FAQs)

What is this funding opportunity?

This opportunity is the Research Centers for Excellence in Clinical Preventive Services (P01) funding opportunity (Funding Opportunity Number RFA-HS-11-005), issued by the Agency for Healthcare Research and Quality (AHRQ). It was designed to support the creation of coordinated research centers focused on practical, high-impact research on clinical preventive services delivered through the health care system.

Which agency is sponsoring the program?

The sponsoring agency is the Agency for Healthcare Research and Quality (AHRQ).

What grant mechanism does this program use?

The program uses the Research Program Project Grant (P01) mechanism, intended for coordinated, multi-project programs where several related research projects and shared cores operate together under one integrated center structure.

What is the core purpose of the Research Program Project Grant (P01) center model in this FOA?

The central purpose is to fund tightly connected research that is stronger as an integrated package than as a set of separate studies. The FOA emphasizes synergy across projects, shared resources and cores, and a common theme that ties the center together.

What does AHRQ mean by "clinical preventive services" in this opportunity?

In this FOA, the emphasis is on clinical preventive services as delivered through the formal health care system, particularly within real clinical workflows. The focus is on how preventive services are selected, implemented, delivered safely, and made routine in health care settings.

How is this different from broad public health prevention funding?

This initiative is not aimed at prevention in the broad public health sense. Instead, it concentrates on what happens inside health care settings, with primary care positioned as a major point of leverage for improving delivery of evidence-based preventive services.

What types of outcomes or system goals are highlighted?

AHRQ frames the work as supporting improvements in population health, effectiveness and efficiency of care, patient safety, and patient experience by strengthening evidence-based preventive service delivery within the health care system.

What was the motivation or policy context mentioned for this initiative?

A key motivation was to accelerate progress aligned with the emerging National Prevention Strategy at the time, by producing actionable evidence about how to implement preventive services well, not only evidence that preventive services work.

What are the programmatic focus areas applicants had to choose from?

Applicants were asked to build a Research Center for Excellence organized around one of three focus areas: (1) patient safety, (2) health equity, or (3) health care system implementation.

What does the patient safety focus area emphasize?

The patient safety focus area emphasizes research that ensures preventive services are delivered in ways that reduce harm, prevent errors, and support safe decision-making in clinical practice.

What does the health equity focus area emphasize?

The health equity focus area emphasizes research that improves the reach, quality, and outcomes of preventive services for populations that experience disparities, including research addressing inequities in access, uptake, and benefits from prevention.

What does the health care system implementation focus area emphasize?

The health care system implementation focus area emphasizes practical research on adopting and sustaining evidence-based preventive services across health systems. Examples in the FOA include workflow integration, organizational change, quality improvement approaches, and strategies for reliable delivery at scale.

What does the FOA expect across all three focus areas?

Across all tracks, the FOA expects the center to function as a coherent, multidisciplinary program capable of producing generalizable knowledge and usable implementation strategies, with projects that collectively reinforce a shared theme.

Who was eligible to apply?

Eligibility was broadly open to a range of public-sector and academic institutions and certain tribal and governmental entities. Eligible applicants included city or township governments, county governments, state governments, public and state-controlled institutions of higher education, federally recognized Native American tribal governments, and other Native American tribal organizations.

Does the eligibility list include federal entities?

Yes. The announcement notes that other eligible applicants include eligible agencies of the Federal Government.

Were tribal governments other than federally recognized entities included?

Yes. The notice indicates eligibility includes Indian/Native American tribal governments other than federally recognized entities, reflecting an intent to enable participation by a wide range of organizations involved in health care delivery, research, and policy.

What is the funding activity category?

The funding activity category is Health.

What CFDA program is associated with this FOA?

The CFDA listing associated with the opportunity is 93.226 (Research on Healthcare Costs, Quality and Outcomes).

Was cost sharing or matching required?

No. The opportunity states there was no cost sharing or matching requirement.

Is this funding opportunity currently open?

No. The timeline indicates it is an archived program announcement. It was posted March 11, 2011, had a closing date of May 23, 2011, and an archive date of June 23, 2011.

What were the important dates listed for the competition?

The FOA was posted on March 11, 2011. The original and current closing date was May 23, 2011. The archive date was June 23, 2011.

Where was the full announcement made available?

The full announcement was made available through an NIH grants webpage link referenced in the notice.

Who was listed for technical access questions about the announcement page?

Technical access questions were directed to the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.

What is the overall goal of funding these centers?

The FOA sought to build a small number of strong, coordinated research centers that could produce innovative and targeted evidence to help the health care system deliver clinical preventive services more safely, more equitably, and more effectively in real-world practice.

What kind of research emphasis is highlighted: proving preventive services work or implementing them well?

The emphasis is on producing actionable evidence on how to implement preventive services well in real clinical settings, not simply proving that they work.

What structural elements are implied by the "multi-project" center approach?

The FOA describes coordinated, multi-project programs where several related research projects and shared cores work together under one integrated center structure, with shared resources and methods supporting synergy across the overall program.

What role does primary care play in this FOA?

Primary care is positioned as a major point of leverage for strengthening how evidence-based clinical preventive services are delivered through the health care system.

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