Opportunity Information: Apply for PAR 09 048
Apply for PAR 09 048
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research Centers in Trauma, Burn, and Peri Operative Injury (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Jan 10, 2012 and posted on Dec 12, 2008.
- Applicants must submit their applications by May 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Private institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:
The Research Centers in Trauma, Burn, and Peri Operative Injury (P50) opportunity (Funding Opportunity Number PAR-09-048) is a National Institutes of Health program run through the National Institute of General Medical Sciences (NIGMS). It is designed to support institution-based research centers that bring multiple investigators and projects together under one coordinated umbrella to study trauma, burn injury, and peri-operative injury, including related critical illness. The central idea is that these conditions trigger complex, multi-system biological responses, and the program is meant to fund centers that can tackle those responses in a coordinated way rather than as isolated, single-project efforts.
The program has three major goals. First, it aims to improve understanding of the biological processes that occur after traumatic injury, burn injury, or in critically ill patients. This includes work at multiple levels, ranging from molecular and cellular mechanisms to whole-body physiology and the way multiple organ systems interact during the loss of homeostasis and the path toward recovery. Second, it emphasizes translational research in both directions: moving basic science discoveries into clinical settings and using clinical observations to shape, test, or validate mechanistic hypotheses. In practice, this encourages research that connects laboratory models and clinical data in a coherent framework, rather than treating them as separate tracks. Third, the FOA prioritizes building and strengthening collaboration, both within an applying institution and across the broader trauma research and clinical community, with the expectation that a funded center functions as a hub for communication, coordination, and shared scientific direction.
Interventional studies can be part of an application, but only when they are clearly integrated with the biological and physiological mechanisms the center is studying. The FOA draws a firm boundary here: a proposal that is essentially just an interventional clinical trial, without a strong mechanistic component or without clear synergy with the center's broader scientific goals, is not considered a good fit for this funding mechanism. In other words, the interventional element has to be tied to understanding or testing biological processes, not simply evaluating whether an intervention works.
Funding is provided through the NIH P50 Research Center grant mechanism, which is typically used for multidisciplinary centers with multiple integrated research components and shared infrastructure. The announcement indicates that award size and duration may vary because centers can differ significantly in scope, complexity, and cost structure. The total number of awards and total dollars available are not fixed in the summary information provided; instead, they depend on factors such as the number of applications submitted, their scientific quality, their proposed budgets, and how long they propose to operate.
Administrative details in the source information show that this is a discretionary grant opportunity in the health category (CFDA 93.859, Biomedical Research and Research Training) and does not require cost sharing or matching. The listed award ceiling is $250,000. The opportunity was posted December 12, 2008, and later archived, with key dates including an original closing date of January 7, 2012, a current closing date of May 7, 2012, and an archive date of June 7, 2012, reflecting that the announcement is no longer open in the provided record.
Eligibility is broad and includes many organizational types, such as public and private institutions of higher education, nonprofit organizations with or without 501(c)(3) status, for-profit organizations (including small businesses and other for-profits), and certain tribal entities and organizations. The eligibility list also explicitly includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, and eligible federal agencies, among others. Additional details and the full FOA were referenced through an NIH Grants Guide link, and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
This opportunity is titled Research Centers in Trauma, Burn, and Peri Operative Injury (P50).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PAR-09-048.
Which federal agency and NIH institute run this program?
This is a National Institutes of Health (NIH) program run through the National Institute of General Medical Sciences (NIGMS).
What is the purpose of the P50 Research Center mechanism in this program?
The program is designed to support institution-based research centers that bring multiple investigators and multiple projects together under one coordinated umbrella to study trauma, burn injury, and peri-operative injury, including related critical illness. The emphasis is on tackling complex, multi-system biological responses through coordinated center-based work rather than isolated single-project efforts.
What scientific areas does this FOA focus on?
The scientific focus is on understanding and studying the biological and physiological responses triggered by traumatic injury, burn injury, and peri-operative injury, including the broader context of critical illness and multi-organ system interactions during loss of homeostasis and recovery.
What are the major goals of the program?
The program has three major goals:
- Improve understanding of biological processes after traumatic injury, burn injury, or in critically ill patients, spanning molecular and cellular mechanisms through whole-body physiology and multi-organ interactions.
- Emphasize translational research in both directions, moving basic discoveries toward clinical application and using clinical observations to shape, test, or validate mechanistic hypotheses.
- Build and strengthen collaboration within the applicant institution and across the broader trauma research and clinical community, positioning the center as a hub for communication and coordinated scientific direction.
Does the FOA support translational research?
Yes. The FOA specifically emphasizes bidirectional translational research: translating basic science discoveries into clinical settings and using clinical findings to guide or validate mechanistic research.
Are clinical interventional studies allowed?
Interventional studies may be included, but only when they are clearly integrated with the biological and physiological mechanisms being studied by the center and when they contribute to the center's broader scientific goals.
Would a stand-alone clinical trial be a good fit for this program?
Not based on the boundaries described. The FOA indicates that a proposal that is essentially just an interventional clinical trial, without a strong mechanistic component or without clear synergy with the center's integrated scientific goals, is not considered a good fit for this funding mechanism.
What type of grant mechanism funds awards under this FOA?
Funding is provided through the NIH P50 Research Center grant mechanism, which is typically used for multidisciplinary centers with multiple integrated research components and shared infrastructure.
Is the award size and duration fixed?
No. The announcement indicates that award size and duration may vary because centers can differ substantially in scope, complexity, and cost structure.
Is the number of awards or total funding amount specified?
Not in the summary information provided. The total number of awards and total dollars available are described as depending on factors such as the number of applications, their scientific quality, the budgets proposed, and the proposed project periods.
What is the listed award ceiling in the provided record?
The provided administrative record lists an award ceiling of $250,000.
Does this opportunity require cost sharing or matching funds?
No. The record indicates that the opportunity does not require cost sharing or matching.
What is the CFDA number and program category?
The record lists CFDA 93.859 and describes the category as Biomedical Research and Research Training (health category), and notes that it is a discretionary grant opportunity.
When was this opportunity posted?
The opportunity was posted on December 12, 2008.
What were the key closing and archive dates shown in the record?
The record shows an original closing date of January 7, 2012, a current closing date of May 7, 2012, and an archive date of June 7, 2012.
Is this FOA currently open for applications?
No. Based on the provided record, the announcement was archived (archive date: June 7, 2012), indicating it is no longer open in that listing.
Who is eligible to apply?
Eligibility is broad and includes many organizational types, including:
- Public and private institutions of higher education
- Nonprofit organizations (with or without 501(c)(3) status)
- For-profit organizations (including small businesses and other for-profits)
- Certain tribal entities and organizations
- Faith-based or community-based organizations
- Eligible federal agencies
Are minority-serving institutions explicitly included in the eligibility list?
Yes. The eligibility list explicitly includes categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and other listed organizational types.
What is the expected structure of the work being proposed?
The FOA is centered on a coordinated, center-based structure that integrates multiple investigators and projects under one umbrella, with an emphasis on synergy, shared scientific direction, and collaboration within and beyond the institution.
How does the FOA describe the scientific rationale for a center approach?
The FOA highlights that trauma, burn injury, and peri-operative injury can trigger complex, multi-system biological responses. The center model is intended to support coordinated work that can address these complex responses more effectively than isolated, single-project efforts.
Where was the full FOA referenced?
The full funding opportunity details were referenced through an NIH Grants Guide link in the source information.
Who should be contacted for technical access issues related to the FOA link or posting?
The source information directs technical access issues to the NIH Office of Extramural Research (OER) webmaster contact.
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