Opportunity Information: Apply for DE FOA 0000448
Apply for DE FOA 0000448
- The Chicago Service Center in the science and technology and other research and development sector is offering a public funding opportunity titled "Research, Development and Training in Isotope Production" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 81.049 Office of Science Financial Assistance Program.
- This funding opportunity was created on Jan 24, 2011 and posted on Jan 24, 2011.
- Applicants must submit their applications by Apr 18, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
- All types of domestic entities are eligible to apply as the lead institution, except other Federal agencies, Federally Funded Research and Development Center (FFRDC) Contractors, and nonprofit organizations described in section 501(c)(4) of the Internal Revenue Code of 1986 that engaged in lobbying activities after December 31, 1995.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The U.S. Department of Energy (DOE) Office of Science, through its Office of Nuclear Physics, released this discretionary grant opportunity to support research, development, and training focused on isotope production. The main goal is to stimulate new or improved ways to produce and separate both stable and radioactive isotopes, especially methods that can strengthen domestic capability and reliability in delivering isotopes that are hard to obtain, expensive, or limited by current production routes. DOE is looking for proposals that either introduce genuinely new technologies or deliver meaningful upgrades to existing production and separation approaches, with an emphasis on practical impact rather than purely theoretical work.
A central theme of the opportunity is enabling better availability of isotopes that are widely used across critical fields. The announcement explicitly ties the expected benefits to medicine (including diagnostic and therapeutic uses), homeland security, and a broad range of research areas in the physical sciences as well as biological and geological sciences. Industrial applications are also within scope, which signals DOE interest in isotope supply chains that support commercial processes, specialized instrumentation, and advanced materials work. In practice, competitive projects would likely be those that can demonstrate clearer pathways to higher yield, higher purity, improved separation efficiency, reduced cost, safer processing, more scalable production, or improved reliability compared with established methods.
Beyond technology development, the DOE also invites applications that tackle the workforce side of isotope production. The opportunity encourages proposals that create or significantly improve education and training efforts aimed at building hands-on expertise in isotope production, processing, purification, and distribution. That focus reflects a recognition that isotope programs depend on specialized personnel who understand nuclear and radiochemical techniques, target preparation, irradiation or production physics, separation chemistry, quality control, packaging and transport constraints, and the regulatory and safety environment around radioactive materials. Strong training proposals would be expected to be more than general outreach, instead offering structured, effective methods to develop personnel capable of advancing isotope production technologies over the long term.
From a funding standpoint, the opportunity was issued as a grant under the Office of Science Financial Assistance Program (CFDA 81.049). DOE anticipated making about six awards, with an estimated total program funding of $3,000,000. Individual awards were expected to fall between $500,000 and $1,500,000, and there was no cost-sharing or matching requirement stated. The funding activity category is science and technology and other research and development, which aligns with the applied R&D nature of isotope production and separation work.
Eligibility was broadly open to domestic entities, described as unrestricted in general terms, but with notable exclusions. Other federal agencies were not eligible to serve as the lead institution, and neither were Federally Funded Research and Development Center (FFRDC) contractors. In addition, certain nonprofit organizations described under section 501(c)(4) that engaged in lobbying activities after December 31, 1995 were excluded. This structure leaves room for universities, national-lab collaborators (depending on their role and contracting status), nonprofit research organizations (outside the excluded category), and private sector entities to participate, either as leads or as partners as allowed by the full announcement.
Key administrative details place this as a time-bounded historical opportunity. It was posted on January 24, 2011, with an application closing date of April 18, 2011, and it was archived on July 23, 2011. The funding opportunity number is DE-FOA-0000448, and it was managed through the DOE Chicago Service Center. For full announcement access, the notice pointed applicants to FedConnect, and provided contacts for a grant analyst (Kerwin A. Lawrence) and a program manager (Dennis R. Phillips), which suggests applicants were expected to coordinate both administrative compliance and technical fit with DOE program priorities.
Overall, this opportunity was designed to push the isotope field forward on two fronts at once: advancing the underlying production and separation technologies that determine isotope availability and quality, and strengthening the pipeline of trained specialists who can operate, improve, and innovate across the full isotope lifecycle from production through purification and distribution.
Frequently Asked Questions (FAQs)
1) What is this DOE funding opportunity about?
This discretionary grant opportunity from the U.S. Department of Energy (DOE) Office of Science, Office of Nuclear Physics supports research, development, and training focused on isotope production. It emphasizes practical, applied work that improves how stable and radioactive isotopes are produced and separated.
2) What is the main goal of the program?
The main goal is to stimulate new or improved methods to produce and separate isotopes, particularly approaches that strengthen domestic capability and reliability for isotopes that are hard to obtain, expensive, or limited by current production routes.
3) What types of isotopes are in scope?
The opportunity covers both stable isotopes and radioactive isotopes, with special interest in those that are difficult to access, costly, or constrained by existing production methods.
4) Is DOE looking for theoretical studies or practical development?
The emphasis is on practical impact rather than purely theoretical work. Competitive proposals would be expected to demonstrate meaningful improvements or genuinely new technologies that can affect real-world isotope production and separation.
5) What kinds of technology improvements are encouraged?
Projects are aligned with improvements such as higher yield, higher purity, better separation efficiency, reduced cost, safer processing, more scalable production, or improved reliability compared with established methods.
6) Which application areas does DOE link to improved isotope availability?
The announcement explicitly ties expected benefits to medicine (including diagnostic and therapeutic uses), homeland security, and research across the physical sciences as well as biological and geological sciences. Industrial applications are also within scope.
7) Are industrial and commercial isotope supply chain needs within scope?
Yes. The inclusion of industrial applications signals interest in isotope supply chains that support commercial processes, specialized instrumentation, and advanced materials work.
8) Does this opportunity fund workforce development and training?
Yes. In addition to technology development, DOE invites applications that create or significantly improve education and training efforts aimed at building hands-on expertise in isotope production, processing, purification, and distribution.
9) What would make a training proposal strong under this announcement?
The opportunity indicates that strong training proposals should be more than general outreach and should offer structured, effective methods to develop personnel capable of advancing isotope production technologies over the long term.
10) What skills and topics does DOE associate with isotope workforce capability?
The announcement highlights the need for specialized personnel with expertise in nuclear and radiochemical techniques, target preparation, irradiation or production physics, separation chemistry, quality control, packaging and transport constraints, and the regulatory and safety environment around radioactive materials.
11) What is the funding mechanism and program identifier?
The opportunity was issued as a grant under the Office of Science Financial Assistance Program, CFDA 81.049.
12) How many awards did DOE anticipate making?
DOE anticipated making about six awards.
13) What was the estimated total funding available?
The estimated total program funding was $3,000,000.
14) What was the expected award size range?
Individual awards were expected to fall between $500,000 and $1,500,000.
15) Was cost sharing or a matching contribution required?
No cost-sharing or matching requirement was stated in the information provided.
16) What is the funding activity category?
The funding activity category is science and technology and other research and development, consistent with applied R&D in isotope production and separation.
17) Who was eligible to apply as a lead institution?
Eligibility was broadly open to domestic entities and described as unrestricted in general terms, subject to specific exclusions listed in the announcement.
18) Which organizations were not eligible to serve as the lead?
Other federal agencies were not eligible to serve as the lead institution. Federally Funded Research and Development Center (FFRDC) contractors were also not eligible to serve as the lead.
19) Are any nonprofit organizations specifically excluded?
Yes. Certain nonprofit organizations described under section 501(c)(4) that engaged in lobbying activities after December 31, 1995 were excluded.
20) What kinds of organizations appear to be able to participate (based on the description)?
The structure leaves room for universities, nonprofit research organizations (outside the excluded category), and private sector entities to participate, either as leads or as partners as allowed by the full announcement. The description also mentions national-lab collaborators depending on their role and contracting status.
21) What is the funding opportunity number?
The funding opportunity number is DE-FOA-0000448.
22) When was the opportunity posted and when did it close?
It was posted on January 24, 2011, and the application closing date was April 18, 2011.
23) Is this an active funding opportunity?
No. It is described as a time-bounded historical opportunity that was archived on July 23, 2011.
24) Which DOE office managed this opportunity?
It was managed through the DOE Chicago Service Center.
25) Where were applicants directed to find the full announcement?
For full announcement access, the notice directed applicants to FedConnect.
26) Who were the listed points of contact?
The information provided lists a grant analyst (Kerwin A. Lawrence) and a program manager (Dennis R. Phillips), indicating separate contacts for administrative compliance and technical/program fit.
Browse more opportunities from the same agency: Chicago Service Center
Browse more opportunities from the same category: Science and Technology and other Research and Development
Next opportunity: OVW Fiscal Year 2011 STOP Violence Against Women Formula Grant Program
Previous opportunity: Support to Local Indigenous Partners in the Implementation and Expansion of High Quality HIV Care, Prevention and Treatment Activities in Faith Based Affiliated Sites in the Republic of Guyana under the President s Emergency Plan for AIDS Relief (PEP
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for DE FOA 0000448
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (DE FOA 0000448) also looked into and applied for these:
| Funding Opportunity |
|---|
| NIST Construction Grant Program (NCGP) Apply for 2011 NIST NCGP 01 Funding Number: 2011 NIST NCGP 01 Agency: National Institute of Standards and Technology Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Basic Research Opportunity Towards Active Control of Noise from Hot Supersonic Jets Apply for 11 SN 0007 Funding Number: 11 SN 0007 Agency: Office of Naval Research Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Cooperative Ecosystem Studies Unit Apply for G11AS20005 Funding Number: G11AS20005 Agency: Geological Survey Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Nanotechnology Undergraduate Education (NUE) in Engineering Apply for 11 524 Funding Number: 11 524 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $200,000 |
| Innovative Technology Experiences for Students and Teachers Apply for 11 525 Funding Number: 11 525 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: $2,150,000 |
| Fostering Interdisciplinary Research on Education Apply for 11 526 Funding Number: 11 526 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| ROSES 2010 NASA Energy and Water Cycle Study Apply for NNH10ZDA001N NEWS Funding Number: NNH10ZDA001N NEWS Agency: NASA Headquarters Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Human Social Cultural and Behavioral Sciences (HSBC) Applied Research and Advanced Technology Development Apply for ONRBAA11 014 Funding Number: ONRBAA11 014 Agency: Office of Naval Research Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Nautilis Taxa Fisheries and Social Surveys Apply for FWS PNW CESU 2011 Funding Number: FWS PNW CESU 2011 Agency: Fish and Wildlife Service Category: Science and Technology and other Research and Development Funding Amount: $100,000 |
| FY12 Communications and Netwo Apply for ONRBAA11 013 Funding Number: ONRBAA11 013 Agency: Office of Naval Research Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Cooperative Ecosystem Studies Unit, South Florida/Caribbean CESU Apply for G11AS20011 Funding Number: G11AS20011 Agency: Geological Survey Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Cooperative Ecosystem Studies Unit, Californian CESU Apply for G11AS20010 Funding Number: G11AS20010 Agency: Geological Survey Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Cooperative Ecosystem Studies Unit Apply for G11AS20007 Funding Number: G11AS20007 Agency: Geological Survey Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Special Program Announcement For 2011 Office of Naval Reserach Basic Research Challenge Reduced Order Representations for Design Development of Analytical and Computational Techniques for Multi physics Based Models of Ship Platforms and Systems Apply for 11 SN 0003 Funding Number: 11 SN 0003 Agency: Office of Naval Research Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Special Program Announcement for 2011 Office of Naval Research Applied Research Data to Decision Apply for 11 SN 0004 Funding Number: 11 SN 0004 Agency: Office of Naval Research Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Notice of Intent to Award Apply for FWS R1 FY2011 Funding Number: FWS R1 FY2011 Agency: Fish and Wildlife Service Category: Science and Technology and other Research and Development Funding Amount: $16,000 |
| Dialysis Like Therapeutics (DLT) Apply for DARPA BAA 11 30 Funding Number: DARPA BAA 11 30 Agency: DARPA Microsystems Technology Office Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Cooperative Ecosystem Studies Unit Apply for G11AS20013 Funding Number: G11AS20013 Agency: Geological Survey Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Cooperative Ecosystem Studies Unit Apply for G11AS20012 Funding Number: G11AS20012 Agency: Geological Survey Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| Metabolomics for a Low Carbon Society Apply for 11 527 Funding Number: 11 527 Agency: National Science Foundation Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "DE FOA 0000448", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.