Opportunity Information: Apply for RFA ES 13 007
Apply for RFA ES 13 007
- The National Institutes of Health in the environment health sector is offering a public funding opportunity titled "Research Linking Environmental Exposure to Neurodegenerative Disease (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health.
- This funding opportunity was created on Oct 21, 2013 and posted on Jul 11, 2013.
- Applicants must submit their applications by Nov 1, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) County governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Public and State controlled institutions of higher education Special district governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Private institutions of higher education City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The National Institutes of Health (NIH), through the National Institute of Environmental Health Sciences (NIEHS), offered this funding opportunity to push forward early stage, exploratory research that connects environmental exposures to neurodegenerative disease. The grant is specifically designed to help investigators generate feasibility or pilot data for new ideas, or to adapt and test emerging technologies, tools, and methods that could strengthen how the field studies environmental contributions to neurodegeneration. While neurodegenerative disease is broadly relevant, the main scientific emphasis is on Alzheimers disease (AD), amyotrophic lateral sclerosis (ALS), and Parkinsons disease (PD). The underlying goal is to accelerate progress toward understanding whether, how, and under what circumstances environmental exposures contribute to disease causation, aligning with NIEHS strategic priorities described in its strategic plan.
This opportunity uses the NIH R21 Exploratory/Developmental Research Grant mechanism, which is typically intended for high risk, high reward concepts and early proof of concept work rather than large, fully powered studies. In practical terms, applicants were expected to propose focused projects that could establish preliminary evidence, demonstrate a new measurement approach, validate a method, build a key dataset, or otherwise reduce uncertainty enough to justify subsequent, larger scale research. The announcement notes it runs in parallel with a companion funding opportunity (RFA ES 13 006) that supports the R01 mechanism, meaning applicants with more mature projects suited to a larger, longer effort were encouraged to consider the R01 track, while this R21 was positioned for earlier stage or method development work.
From an administrative standpoint, this was a discretionary grant opportunity in the environment and health area (CFDA 93.113 Environmental Health). It was posted on July 11, 2013, with an original closing date of October 31, 2013, and a current closing date listed as November 1, 2013; it was archived December 1, 2013. The estimated total funding available was $1,500,000, and the award ceiling was $200,000. The listing also indicates there was no cost sharing or matching requirement, which is important for organizations that may not have flexible non federal funds to contribute.
Eligibility was broad across U.S. based organizations and governments, reflecting an intent to attract ideas from many sectors that could contribute to environmental neurodegeneration research. Eligible applicants included public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain nonprofits without 501(c)(3) status), small businesses, for profit organizations other than small businesses, and a range of governmental entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities or Indian housing authorities. The opportunity also explicitly highlighted additional eligible applicant types such as historically Black colleges and universities (HBCUs), Hispanic serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, Asian American and Native American Pacific Islander serving institutions, faith based or community based organizations, regional organizations, and U.S. territories or possessions. Non U.S. (foreign) institutions and non U.S. components of U.S. organizations were not eligible to apply, though foreign components, as defined in the NIH Grants Policy Statement, were allowed, which can matter for projects that require certain samples, collaborations, or exposure contexts outside the United States while keeping the applicant organization U.S. based.
Overall, the grant opportunity is best understood as an NIH effort to seed innovative, early stage work that can clarify environmental drivers or contributors to major neurodegenerative diseases, strengthen exposure assessment and related methods, and build the preliminary foundation needed for larger definitive studies. The full announcement and application details were provided through the NIH grants guide, and administrative support contacts were listed through the NIH Office of Extramural Research (OER) for access or linking issues.
Frequently Asked Questions (FAQs)
What is the purpose of this NIH/NIEHS funding opportunity?
This funding opportunity was offered by the National Institutes of Health (NIH) through the National Institute of Environmental Health Sciences (NIEHS) to advance early-stage, exploratory research that links environmental exposures to neurodegenerative disease. The intent was to seed new ideas, generate feasibility or pilot data, and/or adapt and test emerging technologies, tools, and methods that can strengthen research on environmental contributions to neurodegeneration.
Which neurodegenerative diseases are emphasized?
While neurodegenerative disease is broadly relevant, the main scientific emphasis is on Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and Parkinson's disease (PD).
What kinds of projects is this grant designed to support?
This opportunity is geared toward focused, early-stage projects that reduce uncertainty and help justify later, larger studies. Examples described in the opportunity include projects that establish preliminary evidence, demonstrate a new measurement approach, validate a method, build a key dataset, or otherwise generate feasibility or pilot data for a novel concept.
What grant mechanism is used for this opportunity?
The opportunity uses the NIH R21 Exploratory/Developmental Research Grant mechanism, which is typically intended for high-risk, high-reward concepts and early proof-of-concept work rather than large, fully powered studies.
How does the R21 focus differ from a larger NIH research grant?
Based on the description provided, the R21 was positioned for earlier-stage research and/or method development work. It was not intended for large, definitive studies. Applicants with more mature projects suited to a larger, longer effort were encouraged to consider the companion R01-track opportunity that ran in parallel.
Is there a companion funding opportunity related to this announcement?
Yes. The announcement notes it ran in parallel with a companion funding opportunity that supports the R01 mechanism (identified as RFA ES 13 006). The R01 track was described as more appropriate for projects that are more mature and suited to a larger, longer research effort.
What is the underlying program goal of this funding opportunity?
The underlying goal is to accelerate progress toward understanding whether, how, and under what circumstances environmental exposures contribute to neurodegenerative disease causation. The opportunity also aligns with NIEHS strategic priorities described in its strategic plan.
What is the CFDA number and general program area?
The listing identifies the opportunity as a discretionary grant in the environment and health area under CFDA 93.113 (Environmental Health).
How much total funding was estimated to be available?
The estimated total funding available was $1,500,000.
What was the award ceiling?
The award ceiling was listed as $200,000.
Was cost sharing or matching required?
No. The listing indicates there was no cost sharing or matching requirement.
Who was eligible to apply?
Eligibility was broad across U.S.-based organizations and governments. Eligible applicants included public and private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), small businesses, and for-profit organizations other than small businesses. A range of governmental entities were also eligible, including state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities or Indian housing authorities.
Were minority-serving institutions and community-based organizations included in eligible applicant types?
Yes. The opportunity explicitly highlighted additional eligible applicant types such as historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, Asian American and Native American Pacific Islander-serving institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.
Are non-U.S. (foreign) institutions eligible to apply as the applicant organization?
No. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations were not eligible to apply as the applicant organization.
Are foreign components allowed if the applicant organization is U.S.-based?
Yes. Although foreign institutions could not apply as the applicant organization, the opportunity states that foreign components (as defined in the NIH Grants Policy Statement) were allowed. This can matter for projects that involve certain samples, collaborations, or exposure contexts outside the United States while keeping the applicant organization U.S.-based.
When was this funding opportunity posted?
It was posted on July 11, 2013.
What were the closing dates listed for the opportunity?
The original closing date was October 31, 2013, and a current closing date was listed as November 1, 2013.
When was the opportunity archived?
The opportunity was archived on December 1, 2013.
Where were the full announcement and application details provided?
The full announcement and application details were provided through the NIH grants guide.
Who was listed as an administrative support contact for access or linking issues?
Administrative support contacts were listed through the NIH Office of Extramural Research (OER) for access or linking issues.
What type of research outcomes were applicants generally expected to produce?
In practical terms, applicants were expected to propose work that could produce feasibility or pilot data, demonstrate or adapt tools/technologies/methods, validate approaches, develop new measurement capabilities, or build datasets that strengthen the field's ability to study environmental contributions to neurodegeneration and support future larger-scale research.
Browse more opportunities from the same agency: National Institutes of Health
Browse more opportunities from the same category: Environment Health
Next opportunity: Hardwood Draw/Riparian Inventory in South Dakota
Previous opportunity: Research Linking Environmental Exposure to Alzheimers Disease (R01)
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA ES 13 007
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (RFA ES 13 007) also looked into and applied for these:
| Funding Opportunity |
|---|
| Novel Methods for Obtaining Molecular Information from Archived Tissue Samples (SBIR R43/R44) Apply for RFA ES 13 009 Funding Number: RFA ES 13 009 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| The Role of Environmental Exposures in the Development of Autoimmune Disease (R21) Apply for RFA ES 13 011 Funding Number: RFA ES 13 011 Agency: National Institutes of Health Category: Environment Health Funding Amount: $200,000 |
| Validation and Demonstration of Devices for Environmental Exposure Assessment (R21/R33) Apply for RFA ES 13 013 Funding Number: RFA ES 13 013 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Outstanding New Environmental Scientist (ONES) Award (R01) Apply for RFA ES 13 014 Funding Number: RFA ES 13 014 Agency: National Institutes of Health Category: Environment Health Funding Amount: $250,000 |
| Environmental Health Sciences Core Centers (EHS CC) (P30) Apply for RFA ES 13 012 Funding Number: RFA ES 13 012 Agency: National Institutes of Health Category: Environment Health Funding Amount: $1,300,000 |
| NIH Revision Awards for Creating Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER)(R01) Apply for PAR 14 050 Funding Number: PAR 14 050 Agency: National Institutes of Health Category: Environment Health Funding Amount: $250,000 |
| Developing Mercury Inventories for Artisanal and Small scale Gold Mining Sectors in Southeast Asia Apply for OES OMM 14 001 Funding Number: OES OMM 14 001 Agency: Ocean and International Environmental Scientific Category: Environment Health Funding Amount: $200,000 |
| Novel Technologies for Rapid and Sensitive Biomonitoring in Humans (R43/R44) Apply for RFA ES 14 005 Funding Number: RFA ES 14 005 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| SBIR E learning for HAZMAT and Emergency Response (R43/R44) Apply for RFA ES 14 003 Funding Number: RFA ES 14 003 Agency: National Institutes of Health Category: Environment Health Funding Amount: $100,000 |
| Undergraduate Research Education Program (UP) to Enhance Diversity in the Environmental Health Sciences (R25) Apply for RFA ES 14 004 Funding Number: RFA ES 14 004 Agency: National Institutes of Health Category: Environment Health Funding Amount: $100,000 |
| Innovative Approaches for the Identification of Mitochondria Cell Signaling Networks in Response to Environmental Stress Apply for RFA ES 14 006 Funding Number: RFA ES 14 006 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Hazmat Training at DOE Nuclear Weapons Complex (UH4) Apply for RFA ES 14 009 Funding Number: RFA ES 14 009 Agency: National Institutes of Health Category: Environment Health Funding Amount: $700,000 |
| Hazardous Materials Worker Health and Safety Training (U45) Apply for RFA ES 14 008 Funding Number: RFA ES 14 008 Agency: National Institutes of Health Category: Environment Health Funding Amount: $700,000 |
| Childrens Environmental Health and Disease Prevention Research Centers (P50) Apply for RFA ES 14 002 Funding Number: RFA ES 14 002 Agency: National Institutes of Health Category: Environment Health Funding Amount: $1,500,000 |
| Outstanding New Environmental Scientist (ONES) Award (R01) Apply for RFA ES 15 003 Funding Number: RFA ES 15 003 Agency: National Institutes of Health Category: Environment Health Funding Amount: $475,000 |
| Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (R41) Apply for RFA ES 15 005 Funding Number: RFA ES 15 005 Agency: National Institutes of Health Category: Environment Health Funding Amount: $225,000 |
| Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (R43/R44) Apply for RFA ES 15 006 Funding Number: RFA ES 15 006 Agency: National Institutes of Health Category: Environment Health Funding Amount: $225,000 |
| Environmental Health Sciences Core Centers (EHS CC) (P30) Apply for RFA ES 15 007 Funding Number: RFA ES 15 007 Agency: National Institutes of Health Category: Environment Health Funding Amount: Case Dependent |
| Collaborative Activities to promote High Dimensional Molecular Analyses in NIEHS supported Childrens Environmental Health Studies (Admin Supp) Apply for PA 15 123 Funding Number: PA 15 123 Agency: National Institutes of Health Category: Environment Health Funding Amount: $300,000 |
| Childrens Health Exposure Analysis Resource (CHEAR) National Exposure Assessment Laboratory Network (U2C) Apply for RFA ES 15 009 Funding Number: RFA ES 15 009 Agency: National Institutes of Health Category: Environment Health Funding Amount: $8,000,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants

Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA ES 13 007", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.
