Opportunity Information: Apply for PA 10 104

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research on Alcohol and HIV/AIDS (R03)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Feb 1, 2010 and posted on Feb 1, 2010.
  • Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) City or township governments For profit organizations other than small businesses County governments Native American tribal governments (Federally recognized) Private institutions of higher education Public housing authorities/Indian housing authorities Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments Small businesses Independent school districts Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The NIH funding opportunity "Research on Alcohol and HIV/AIDS (R03)" (Funding Opportunity Number PA-10-104) supports small, focused research projects that explore the connections between alcohol use and HIV/AIDS. The main goal is to broaden participation in this research space by welcoming investigators from either field who may not yet have experience in the other. In practical terms, the announcement is designed for alcohol researchers who recognize that problem drinking can affect HIV risk, treatment, and outcomes and want to build HIV-related expertise, as well as HIV/AIDS researchers who see alcohol as a major and sometimes under-addressed factor in prevention and care and want to develop stronger alcohol-related research or intervention approaches. It also explicitly encourages proposals from investigators already working on the overlap between HIV/AIDS and alcohol or other substance use, reflecting the fact that co-occurring conditions are common and clinically important.

This FOA uses the NIH R03 mechanism, which is intended for short-term, limited-budget projects that can be completed with relatively modest resources. The R03 format is especially well suited to early-stage work that helps generate preliminary data or tests whether a larger study is feasible. The announcement highlights several types of projects that fit the R03 model: pilot and feasibility studies, secondary analyses of existing datasets, small self-contained research projects, development or refinement of research methods, and development of new research technologies. In other words, this is not primarily aimed at large clinical trials or multi-site studies; it is aimed at tightly scoped projects that can answer a specific question, validate an approach, or lay the groundwork for subsequent R01- or R21-level applications.

The scientific scope is framed broadly around alcohol and HIV/AIDS, with an emphasis on how alcohol use and alcohol-related interventions may influence HIV prevention, disease progression, treatment adherence, and clinical outcomes. The announcement signals a particular interest in work that could inform more intensive or more effective alcohol interventions for people living with HIV, since alcohol use can complicate care engagement and health outcomes. Because the FOA covers a wide range of possible objectives and approaches, applicants are encouraged to read the full announcement carefully to identify the best fit for their specific research idea and to align the proposed aims with what an R03 can realistically accomplish.

This opportunity runs in parallel with companion FOAs of the same scientific scope that support larger or different kinds of projects: PA-10-103 (R01) and PA-10-105 (R21). That structure gives applicants flexibility to choose the mechanism that matches their project size and maturity, while keeping the research focus consistent across mechanisms.

Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (including small businesses), local and state governments, tribal governments and tribal organizations, U.S. territories and possessions, public housing authorities, independent school districts, and special district governments. The eligibility list also explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, faith-based or community-based organizations, and foreign organizations, among others. There is no cost sharing or matching requirement.

The FOA falls under CFDA 93.273 (Alcohol Research Programs) and is issued by the National Institutes of Health. The opportunity was posted and created on February 1, 2010, with an original and current closing date of January 7, 2013, and it was archived on February 7, 2013. Awards were not guaranteed; as with many NIH announcements, the number of awards and total funding depended on the availability of funds and the receipt of a sufficient number of highly competitive applications. For full details, NIH referenced the complete announcement at http://grants.nih.gov/grants/guide/pa-files/PA-10-104.html and provided NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues.

FAQs: NIH Research on Alcohol and HIV/AIDS (R03) - PA-10-104

What is the title of this NIH funding opportunity?

The funding opportunity is titled "Research on Alcohol and HIV/AIDS (R03)".

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PA-10-104.

Which agency is offering this opportunity?

This opportunity is issued by the National Institutes of Health (NIH).

What is the CFDA number associated with this FOA?

The FOA is listed under CFDA 93.273 (Alcohol Research Programs).

What is the main purpose of this R03 announcement?

The main purpose is to support small, focused research projects that explore connections between alcohol use and HIV/AIDS, while broadening participation by welcoming investigators from either field who may not yet have experience in the other.

Who is this FOA designed to encourage?

It is designed to encourage:

  • Alcohol researchers who want to build HIV-related expertise because problem drinking can affect HIV risk, treatment, and outcomes.
  • HIV/AIDS researchers who want to strengthen alcohol-related research or intervention approaches because alcohol can be a major and under-addressed factor in prevention and care.
  • Investigators already working on the overlap between HIV/AIDS and alcohol or other substance use, reflecting the clinical importance of co-occurring conditions.

What grant mechanism does this FOA use?

This FOA uses the NIH R03 mechanism.

What kind of projects are best suited to the R03 mechanism in this FOA?

The R03 mechanism is intended for short-term, limited-budget projects that can be completed with modest resources and are often used to generate preliminary data or test feasibility. The FOA highlights project types such as:

  • Pilot and feasibility studies
  • Secondary analyses of existing datasets
  • Small, self-contained research projects
  • Development or refinement of research methods
  • Development of new research technologies

Is this FOA meant for large clinical trials or multi-site studies?

No. The announcement is positioned for tightly scoped projects appropriate for an R03, rather than large clinical trials or multi-site studies.

What scientific topics are within scope?

The scientific scope is broadly focused on alcohol and HIV/AIDS, including how alcohol use and alcohol-related interventions may influence:

  • HIV prevention
  • Disease progression
  • Treatment adherence
  • Clinical outcomes

Does the FOA highlight any particular area of interest within alcohol and HIV?

Yes. It signals particular interest in work that could inform more intensive or more effective alcohol interventions for people living with HIV, since alcohol use can complicate engagement in care and health outcomes.

Are applicants expected to keep the project scope realistic for an R03?

Yes. Because the FOA covers a wide range of objectives and approaches, applicants are encouraged to align proposed aims with what an R03 can realistically accomplish.

Are there companion FOAs with the same scientific scope?

Yes. This opportunity runs in parallel with companion FOAs of the same scientific scope:

  • PA-10-103 (R01)
  • PA-10-105 (R21)

Why does NIH offer companion FOAs (R01 and R21) alongside this R03?

The companion FOAs provide flexibility to choose a mechanism that matches a project's size and maturity, while keeping the research focus consistent across mechanisms.

Who is eligible to apply?

Eligibility is broad and includes many types of domestic and non-domestic organizations. Examples listed include:

  • Public and private institutions of higher education
  • Nonprofit organizations (with or without 501(c)(3) status)
  • For-profit organizations (including small businesses)
  • Local and state governments
  • Tribal governments and tribal organizations
  • U.S. territories and possessions
  • Public housing authorities
  • Independent school districts
  • Special district governments
  • Faith-based or community-based organizations
  • Foreign organizations

Does the eligibility list mention specific institution types such as HBCUs or Tribal colleges?

Yes. The eligibility list explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian-serving institutions, among others.

Is there a cost sharing or matching requirement?

No. There is no cost sharing or matching requirement.

When was this FOA posted and created?

The FOA was posted and created on February 1, 2010.

What was the closing date for this opportunity?

The original and current closing date listed is January 7, 2013.

Is this FOA still open?

No. The FOA was archived on February 7, 2013.

Were awards guaranteed under this FOA?

No. Awards were not guaranteed. The number of awards and total funding depended on the availability of funds and the receipt of a sufficient number of highly competitive applications.

Where can applicants find the full FOA text?

NIH referenced the complete announcement at: http://grants.nih.gov/grants/guide/pa-files/PA-10-104.html

Who is listed for help with access or linking issues?

The information provided indicates that NIH included contacts for the NIH Office of Extramural Research (OER) webmaster for access or linking issues.

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