Opportunity Information: Apply for PA 10 105

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research on Alcohol and HIV/AIDS (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Feb 3, 2010 and posted on Feb 3, 2010.
  • Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) County governments Private institutions of higher education Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public and State controlled institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Special district governments Small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The NIH funding opportunity titled Research on Alcohol and HIV/AIDS (R21) (Funding Opportunity Number PA-10-105) supports exploratory and developmental research that strengthens the evidence base at the intersection of alcohol use and HIV/AIDS. The core idea is to bring more researchers into this cross-cutting area, especially investigators who may be strong in one field but have limited experience in the other. It is designed to attract alcohol researchers who recognize how problem drinking can affect HIV risk and HIV-related outcomes, HIV/AIDS researchers who see the need to address alcohol use more directly to improve prevention and clinical care results, and teams that already work on co-occurring HIV and alcohol or broader substance use issues but want to test newer concepts or pilot emerging approaches.

This announcement uses the NIH R21 mechanism, which is meant for early-stage, high-potential projects that can generate preliminary data, prove feasibility, or open up new directions that later can be scaled into larger studies. In other words, the expectation is not necessarily a fully mature, multi-year definitive trial, but rather an innovative project that can establish whether an idea is workable and scientifically promising in the alcohol and HIV/AIDS space. The FOA also notes that it is part of a coordinated set of opportunities with the same scientific scope offered under other NIH mechanisms: an R01 version (PA-10-103) for more comprehensive, full-scale research projects, and an R03 version (PA-10-104) for smaller, more limited studies. Applicants are encouraged to review the full announcement carefully because the range of possible research objectives is broad and can accommodate many angles, populations, and methods.

Funding levels and the number of awards are not fixed in advance because NIH expects applications to vary widely in scope, duration, and budget needs. That said, the listing includes an award ceiling of $200,000 (as presented in the opportunity summary), and NIH indicates that the total number of awards and total dollars will ultimately depend on the number of submissions, their scientific quality, the requested project periods, and the costs proposed. There is no cost sharing or matching requirement, which helps reduce barriers for organizations that cannot contribute non-federal funds.

Eligibility is intentionally wide to encourage participation from many types of institutions and community settings relevant to HIV and alcohol research. Eligible applicants include state, county, city, township, and special district governments; public and private institutions of higher education; public and state-controlled universities; independent school districts; public housing authorities and Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status (with the noted exception category regarding institutions of higher education); for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly includes a variety of additional eligible entities such as federally recognized and other tribal governments and organizations, historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, U.S. territories or possessions, regional organizations, eligible federal agencies, and non-U.S. (foreign) organizations. This breadth signals NIH interest in supporting research that can be conducted in diverse healthcare, community, and international contexts where alcohol use and HIV burdens overlap.

Administratively, the opportunity is categorized as a discretionary grant within the health area and is listed under CFDA 93.273 (Alcohol Research Programs). It was posted on February 3, 2010, and the original and current closing date shown is January 7, 2013, with an archive date of February 7, 2013, indicating it is no longer active but remains useful as a reference for how NIH framed this research priority. The sponsoring agency is the National Institutes of Health, and the full archived announcement was made available through the NIH grants guide at the provided link (http://grants.nih.gov/grants/guide/pa-files/PA-10-105.html). For access or technical issues related to the posting, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs): NIH PA-10-105 - Research on Alcohol and HIV/AIDS (R21)

What is the name of this NIH funding opportunity?

The funding opportunity is titled Research on Alcohol and HIV/AIDS (R21).

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PA-10-105.

What is the main purpose of PA-10-105?

This opportunity supports exploratory and developmental research to strengthen the evidence base at the intersection of alcohol use and HIV/AIDS. A key goal is to encourage more research activity in this cross-cutting area, including participation from investigators who are strong in one field but have limited experience in the other.

What types of researchers is this FOA trying to attract?

The FOA is designed to attract:

  • Alcohol researchers who recognize that problem drinking can influence HIV risk and HIV-related outcomes
  • HIV/AIDS researchers who want to address alcohol use more directly to improve prevention and clinical care results
  • Teams already studying co-occurring HIV and alcohol (or broader substance use) who want to test newer concepts or pilot emerging approaches

What grant mechanism does this opportunity use?

This announcement uses the NIH R21 mechanism.

What does the NIH R21 mechanism emphasize?

The R21 mechanism is intended for early-stage, high-potential projects that can:

  • Generate preliminary data
  • Demonstrate feasibility
  • Open new directions that could later be scaled into larger studies

The expectation is not necessarily a fully mature, multi-year definitive trial, but an innovative project that tests whether an idea is workable and scientifically promising in the alcohol and HIV/AIDS space.

Is this FOA connected to other NIH opportunities on the same topic?

Yes. NIH notes this R21 is part of a coordinated set of opportunities with the same scientific scope offered under other mechanisms, including:

  • R01 version: PA-10-103 (more comprehensive, full-scale research projects)
  • R03 version: PA-10-104 (smaller, more limited studies)

How broad is the scope of eligible research topics?

The FOA describes the scientific scope as broad and able to accommodate many angles, populations, and methods within the intersection of alcohol use and HIV/AIDS. Applicants are encouraged to review the full announcement carefully due to the wide range of possible research objectives.

How much funding is available per award?

The opportunity summary includes an award ceiling of $200,000.

Are the number of awards and total available funding fixed?

No. NIH indicates that the number of awards and total dollars are not fixed in advance and will depend on factors such as:

  • The number of submissions received
  • The scientific quality of applications
  • Requested project periods
  • Proposed costs

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement for this opportunity.

Who is eligible to apply?

Eligibility is intentionally broad. Eligible applicants include a wide range of organizations and institutions, including:

  • State, county, city, township, and special district governments
  • Public and private institutions of higher education
  • Public and state-controlled universities
  • Independent school districts
  • Public housing authorities and Indian housing authorities
  • Nonprofit organizations (with and without 501(c)(3) status, with the noted exception category regarding institutions of higher education)
  • For-profit organizations (other than small businesses)
  • Small businesses
  • Federally recognized tribal governments and other tribal governments and organizations
  • Historically Black Colleges and Universities (HBCUs)
  • Hispanic-serving institutions
  • Tribally Controlled Colleges and Universities (TCCUs)
  • Alaska Native and Native Hawaiian Serving Institutions
  • Faith-based and community-based organizations
  • U.S. territories or possessions
  • Regional organizations
  • Eligible federal agencies
  • Non-U.S. (foreign) organizations

Does NIH allow non-U.S. (foreign) organizations to apply?

Yes. The eligibility list explicitly includes non-U.S. (foreign) organizations.

What agency sponsors this funding opportunity?

The sponsoring agency is the National Institutes of Health (NIH).

How is this opportunity categorized?

The opportunity is categorized as a discretionary grant in the health area.

What is the CFDA number associated with this opportunity?

The listing references CFDA 93.273 (Alcohol Research Programs).

When was this opportunity posted?

It was posted on February 3, 2010.

What is the closing date shown for this opportunity?

The original and current closing date shown is January 7, 2013.

Is PA-10-105 still open for applications?

No. The listing includes an archive date of February 7, 2013, indicating the opportunity is no longer active and is presented as an archived reference.

Where can someone find the full archived announcement?

The full archived announcement is available through the NIH grants guide at: http://grants.nih.gov/grants/guide/pa-files/PA-10-105.html

Who should be contacted for access or technical issues related to the posting?

For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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