Opportunity Information: Apply for PA 07 428

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research on Alcohol Related Public Policies such as Those Detailed in the Alcohol Policy Information System (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Dec 5, 2008 and posted on Aug 8, 2007.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Special district governments Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) State governments Private institutions of higher education For profit organizations other than small businesses.
  • Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
Apply for PA 07 428

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Opportunity Summary:

This grant opportunity, titled "Research on Alcohol Related Public Policies such as Those Detailed in the Alcohol Policy Information System (R21)" (Funding Opportunity Number PA-07-428), is a National Institutes of Health program run through the National Institute on Alcohol Abuse and Alcoholism (NIAAA). It supports exploratory, early-stage research that looks at how alcohol-related public policies shape real-world health behaviors and health outcomes. The core idea is to fund studies that can clarify what policy approaches work, for whom they work, and under what conditions they reduce alcohol-related harm, illness, and death. A major emphasis is on policy-relevant evidence, including research that helps public health and government decision-makers understand the measurable impact of different policy tools.

The scientific scope is centered on three connected aims. First, applicants are encouraged to study the effects of alcohol-related public policies on health-related behaviors and outcomes, which can include patterns of alcohol consumption, risky drinking, underage drinking, impaired driving, violence, injury, chronic disease outcomes, and other alcohol-attributable harms. Second, the FOA explicitly calls for evaluations and analyses of the effectiveness of policy measures, meaning it is not just descriptive policy research, but research designed to assess whether policies improve public health and reduce the burden of alcohol-related illness and mortality. Third, it also invites work that advances the methods and measurement used in this field, such as improving how policies are classified and quantified, strengthening causal inference approaches for policy evaluation, refining outcome measurement, and building better analytic frameworks for linking policy environments to health endpoints.

The mechanism of support is the NIH Exploratory/Developmental Research Grant (R21). In practical terms, the R21 mechanism is typically used for projects that are innovative, potentially high-impact, and still at a stage where a smaller, more flexible award can generate pilot data, test new methodologies, or explore emerging hypotheses before a larger-scale study. This FOA is described as running in parallel with two other announcements of the same scientific scope that use different grant mechanisms: PA-07-427 (R01) and PA-07-429 (R03). That matters because it signals the agency is trying to support a pipeline of work in alcohol policy research, from small pilots (R03), to exploratory/developmental projects (R21), to full-scale studies (R01), depending on the maturity and scale of the proposed research.

Funding levels and the number of awards are not fixed because the FOA anticipates a wide range of study designs, data sources, and project scopes. That said, the posted award ceiling is $200,000, and the agency notes that both the size and duration of each award may vary depending on what is proposed. Ultimately, how many awards are made and at what levels depends on the mix of applications received, their quality, their budgets, and their timelines, which is typical for NIH discretionary research programs.

Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), for-profit organizations (including small businesses), state and local governments (state, county, city/township, special districts), independent school districts, public housing authorities/Indian housing authorities, and Native American tribal governments and organizations. The opportunity also states that foreign institutions are eligible to apply, that eligible federal agencies may apply, and that faith-based or community-based organizations are not excluded. There is no cost sharing or matching requirement, which lowers the barrier for organizations that may not have discretionary funds to contribute.

The opportunity is categorized as a discretionary grant in the health area and is associated with CFDA number 93.273 (Alcohol Research Programs). It was posted on August 8, 2007, includes multiple receipt dates rather than a single deadline, and was later archived (archive date October 10, 2010). The full announcement is linked through the NIH Grants Guide (http://grants.nih.gov/grants/guide/pa-files/PA-07-428.html), and the NIH Office of Extramural Research provides webmaster contact information for access or technical issues related to the posting.

Frequently Asked Questions (FAQs)

What is the title of this grant opportunity?

The opportunity is titled "Research on Alcohol Related Public Policies such as Those Detailed in the Alcohol Policy Information System (R21)."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is PA-07-428.

Which agency and institute run this program?

This is a National Institutes of Health (NIH) program run through the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

What is the main purpose of this FOA?

The FOA supports exploratory, early-stage research examining how alcohol-related public policies influence real-world health behaviors and health outcomes. The overall goal is to generate policy-relevant evidence about what policy approaches work, for whom they work, and under what conditions they reduce alcohol-related harm, illness, and death.

What kinds of research are encouraged under this opportunity?

The announcement emphasizes research that can clarify measurable impacts of alcohol-related public policies and help inform public health and government decision-makers about the effectiveness of different policy tools.

What are the key scientific aims described in the FOA?

The scope is organized around three connected aims: (1) studying the effects of alcohol-related public policies on health-related behaviors and outcomes; (2) evaluating and analyzing the effectiveness of policy measures (not just describing them); and (3) advancing methods and measurement for alcohol policy research, including policy classification/quantification, causal inference approaches, outcome measurement, and analytic frameworks linking policy environments to health endpoints.

What outcomes or behaviors may be studied?

Examples mentioned include patterns of alcohol consumption, risky drinking, underage drinking, impaired driving, violence, injury, chronic disease outcomes, and other alcohol-attributable harms.

Is this FOA focused on descriptive policy research or policy evaluation?

It explicitly calls for evaluations and analyses of the effectiveness of policy measures, indicating the intent is to assess whether policies improve public health and reduce alcohol-related illness and mortality, rather than only describing policies.

Does the FOA support methods development work?

Yes. It invites work that improves methods and measurement, such as better ways to classify and quantify policies, stronger causal inference approaches for policy evaluation, refined outcome measurement, and improved analytic frameworks linking policy environments to health outcomes.

What grant mechanism is used for this opportunity?

The mechanism is the NIH Exploratory/Developmental Research Grant (R21).

What does the R21 mechanism imply about the type of project expected?

R21 awards are typically used for innovative, potentially high-impact projects at an exploratory or early stage, such as generating pilot data, testing new methodologies, or exploring emerging hypotheses before a larger-scale study.

Are there related funding announcements with the same scientific scope?

Yes. This FOA runs in parallel with PA-07-427 (R01) and PA-07-429 (R03), which share the same scientific scope but use different NIH grant mechanisms.

How does this FOA relate to the R03 and R01 versions?

The three announcements signal a pipeline of support for alcohol policy research, spanning small pilot projects (R03), exploratory/developmental studies (R21), and full-scale research projects (R01), depending on project maturity and scale.

How much funding is available per award?

The posted award ceiling is $200,000. The FOA also notes that award size and duration may vary depending on what is proposed.

Is the number of awards fixed?

No. Funding levels and the number of awards are not fixed and depend on the range of applications received, their quality, requested budgets, and proposed timelines.

Who is eligible to apply?

Eligibility is broad and includes many U.S. and non-U.S. organizations, such as public and private institutions of higher education, nonprofits (501(c)(3) and non-501(c)(3)), for-profit organizations (including small businesses), state and local governments (including special districts), independent school districts, public housing authorities/Indian housing authorities, and Native American tribal governments and organizations.

Are foreign institutions eligible to apply?

Yes. The opportunity states that foreign institutions are eligible.

Can federal agencies apply?

Yes. The opportunity states that eligible federal agencies may apply.

Are faith-based or community-based organizations excluded?

No. The FOA states that faith-based or community-based organizations are not excluded.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

How is this opportunity categorized (grant type and topic area)?

It is categorized as a discretionary grant in the health area.

What CFDA number is associated with this program?

The associated CFDA number is 93.273 (Alcohol Research Programs).

When was this opportunity posted?

It was posted on August 8, 2007.

Is there a single deadline to apply?

No. The posting indicates multiple receipt dates rather than a single deadline.

Has this funding opportunity been archived?

Yes. It was later archived, with an archive date of October 10, 2010.

Where can applicants find the full FOA text?

The full announcement is available through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PA-07-428.html.

Who is listed for technical or access issues related to the posting?

The NIH Office of Extramural Research provides webmaster contact information for access or technical issues related to the posting.

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