Opportunity Information: Apply for PA 07 047
Apply for PA 07 047
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Research on Chronic Insomnia Disorder (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.361 Nursing Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.866 Aging Research.
- This funding opportunity was created on Dec 5, 2008 and posted on Nov 21, 2006.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education City or township governments Special district governments Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments County governments For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public housing authorities/Indian housing authorities.
- Foreign institutions are eligible to apply. Faith based or community based organizations can apply.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The NIH grant opportunity "Research on Chronic Insomnia Disorder (R01)" (Funding Opportunity Number PA-07-047) supports investigator-initiated research projects aimed at improving the scientific understanding and clinical management of chronic insomnia disorder. The program is rooted in the public health burden of insomnia, which affects roughly 10 percent of adults in the United States and is linked to meaningful real-world consequences such as reduced work and academic performance, higher accident risk, increased health care utilization and costs, and elevated risk for depression and other mental health conditions. This funding announcement was developed in response to the NIH State of the Science Conference on "Manifestations and Management of Chronic Insomnia in Adults" held in June 2005, where experts summarized the evidence base and identified major gaps that need targeted research. The central goal of the FOA is to drive studies that directly address those gaps and move the field forward in both basic science and applied clinical directions.
A major emphasis of the FOA is on clarifying underlying mechanisms of insomnia, including genetic influences and neurobiological pathways that contribute to persistent sleep disturbance. By encouraging mechanistic work, the announcement signals interest in research that can explain why insomnia becomes chronic in some individuals, how it is maintained over time, and how biological vulnerabilities interact with behavior, stress, and environment. Alongside mechanistic science, the FOA encourages longitudinal and developmental research that tracks the incidence, persistence, remission, and recurrence of insomnia across time. These kinds of studies can help identify risk factors, protective factors, typical trajectories, and critical periods where prevention or early intervention may be most effective.
Another priority area is improving how insomnia-related impairment is measured, especially in terms of daytime functioning and quality of life. The FOA points to the need for better tools and approaches that capture the real-life impact of insomnia beyond nighttime symptoms alone. This can include more sensitive or valid measures of cognitive performance, mood and emotional regulation, occupational functioning, social functioning, and broader health-related quality of life. Better measurement is also tied to better clinical trials and better translation to practice, because treatment effectiveness depends on outcomes that matter to patients and health systems.
The announcement also calls for research in special populations, reflecting the reality that insomnia does not affect all groups in the same way and that certain populations may have unique risks, presentations, or treatment needs. While the FOA does not list every population in the summary text provided, the intent is to stimulate studies that consider differences across age groups, comorbid medical or psychiatric conditions, and other populations where insomnia may be understudied or harder to treat. Relatedly, the FOA highlights interest in research examining how insomnia contributes to the development or worsening of other disorders, including depression, substance use and drug abuse, and chronic medical diseases. This direction reflects the growing view of insomnia not only as a symptom but also as a potential causal or amplifying factor in broader mental and physical health outcomes.
On the intervention side, the FOA supports the development, evaluation, and dissemination of treatments for chronic insomnia. This includes research that tests new or improved treatment approaches, evaluates effectiveness in real-world settings, and addresses how evidence-based care can be delivered at scale. Dissemination and implementation considerations are important here because even when effective treatments exist, access and uptake can remain limited due to workforce constraints, cost, geography, comorbidity, or system barriers. A particularly encouraged theme is translational research that takes basic science findings and turns them into novel clinical approaches, reflecting NIH interest in moving discoveries from bench to bedside and into community practice.
From an administrative and eligibility perspective, this opportunity uses the NIH R01 mechanism, meaning it is designed for substantial, hypothesis-driven or programmatic research projects that can be carried out over multiple years with clearly defined aims. It is categorized as a discretionary grant and falls under health and education-related activity categories, with CFDA listings that include mental health research, nursing research, neurosciences and neurological disorders research, and aging research (93.242, 93.361, 93.853, 93.866). Cost sharing or matching is not required, which reduces financial barriers for applicants. The opportunity was originally posted on November 21, 2006, with multiple receipt dates (rather than a single deadline), and the record indicates an archive date of February 2, 2010, meaning it was time-limited as a specific announcement even though similar priorities may continue under newer NIH sleep and insomnia-related funding calls.
Eligibility is broad and includes many U.S.-based entity types such as public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), small businesses, for-profit organizations (including those other than small businesses), and a range of government entities (state, county, city/township, special district governments, and independent school districts). The FOA explicitly allows applications from foreign institutions and notes that faith-based and community-based organizations may also apply, which widens the pool of potential applicants and can support international or community-engaged research. The sponsoring agency is the National Institutes of Health, and the full announcement was made available through the NIH grants guide site. Contact information in the listing directs technical access and linking issues to the NIH Office of Extramural Research (OER) webmaster.
Frequently Asked Questions (FAQs): NIH "Research on Chronic Insomnia Disorder (R01)" (PA-07-047)
1) What is this funding opportunity?
This is an NIH Funding Opportunity Announcement (FOA) titled "Research on Chronic Insomnia Disorder (R01)", with Funding Opportunity Number PA-07-047. It supports investigator-initiated research projects focused on advancing the scientific understanding and clinical management of chronic insomnia disorder using the NIH R01 grant mechanism.
2) What is the main goal of PA-07-047?
The central goal is to fund research that addresses key evidence gaps identified by experts and moves the field forward in both basic science and applied clinical directions. The FOA is intended to improve understanding of chronic insomnia and strengthen how it is assessed, treated, and managed in real-world settings.
3) Why is NIH prioritizing research on chronic insomnia disorder?
The FOA is rooted in the public health burden of insomnia. The opportunity notes that insomnia affects roughly 10 percent of adults in the United States and is linked to meaningful consequences such as reduced work and academic performance, higher accident risk, increased health care utilization and costs, and elevated risk for depression and other mental health conditions.
4) What prompted NIH to develop this FOA?
This funding announcement was developed in response to the NIH State of the Science Conference on "Manifestations and Management of Chronic Insomnia in Adults" held in June 2005. At that conference, experts summarized the evidence base and identified major gaps requiring targeted research, which this FOA is designed to address.
5) What kinds of research topics does the FOA emphasize?
The FOA emphasizes several broad and connected priority areas, including:
- Clarifying underlying mechanisms of insomnia (including genetic influences and neurobiological pathways)
- Understanding why insomnia becomes chronic and how it is maintained over time
- How biological vulnerabilities interact with behavior, stress, and environment
- Longitudinal and developmental studies on incidence, persistence, remission, and recurrence
- Improving measurement of insomnia-related impairment (especially daytime functioning and quality of life)
- Research in special populations and understudied groups
- Examining insomnia as a contributor to other disorders (including depression, substance use/drug abuse, and chronic medical diseases)
- Intervention development, evaluation, dissemination, and implementation
- Translational research that turns basic science findings into novel clinical approaches
6) Does the FOA support basic science research, clinical research, or both?
Both. The FOA explicitly encourages mechanistic research (basic science directions such as genetic and neurobiological pathways) and applied clinical research (such as improving assessment of impairment and testing interventions in real-world settings). It also highlights translational work linking basic discoveries to clinical approaches.
7) What does the FOA mean by "mechanisms" of chronic insomnia?
Mechanistic research in this FOA includes work on genetic influences and neurobiological pathways that contribute to persistent sleep disturbance. The intent is to better explain why insomnia becomes chronic in some individuals, how it is sustained over time, and how biology interacts with behavioral, stress-related, and environmental factors.
8) Are longitudinal or developmental studies encouraged?
Yes. The FOA encourages longitudinal and developmental research that can track insomnia over time, including its incidence, persistence, remission, and recurrence. These studies are positioned as important for identifying risk and protective factors, typical trajectories, and critical periods for prevention or early intervention.
9) Is there interest in improving how insomnia-related impairment is measured?
Yes. A stated priority is improving the measurement of insomnia-related impairment, particularly related to daytime functioning and quality of life. The FOA notes the need for tools and approaches that capture real-life impact beyond nighttime symptoms alone.
10) What types of outcomes or impairment domains are highlighted?
The FOA points to the value of more sensitive or valid measures of outcomes such as cognitive performance, mood and emotional regulation, occupational functioning, social functioning, and broader health-related quality of life.
11) Does the FOA encourage research in special populations?
Yes. The FOA calls for research in special populations, reflecting that insomnia may differ in risk, presentation, or treatment needs across groups. While the summary does not list every group, it signals interest in differences across age groups, comorbid medical or psychiatric conditions, and other understudied or harder-to-treat populations.
12) Does the FOA support research on insomnia's relationship to other disorders?
Yes. The FOA highlights interest in research examining how insomnia contributes to the development or worsening of other disorders, including depression, substance use and drug abuse, and chronic medical diseases. This reflects a view of insomnia as potentially more than a symptom and possibly a causal or amplifying factor in broader health outcomes.
13) What kinds of intervention research are supported?
The FOA supports intervention-oriented work including the development, evaluation, and dissemination of treatments for chronic insomnia. This can include testing new or improved approaches, evaluating effectiveness in real-world settings, and addressing how evidence-based care can be delivered at scale.
14) Does the FOA include dissemination and implementation considerations?
Yes. The FOA specifically notes that dissemination and implementation matter because even when effective treatments exist, access and uptake may be limited by workforce constraints, cost, geography, comorbidity, or system barriers. Research addressing these practical barriers aligns with the FOA's priorities.
15) What is meant by translational research in this FOA?
Translational research here refers to studies that take basic science findings (for example, mechanistic insights) and translate them into novel clinical approaches, supporting movement from bench to bedside and into community practice.
16) What grant mechanism does this opportunity use?
This FOA uses the NIH R01 mechanism. It is intended for substantial, hypothesis-driven or programmatic research projects that can be carried out over multiple years with clearly defined aims.
17) What is the type of grant and activity area classification?
The opportunity is categorized as a discretionary grant and falls under health and education-related activity categories. It also lists CFDA areas including mental health research, nursing research, neurosciences and neurological disorders research, and aging research.
18) What CFDA program areas are associated with this FOA?
The FOA lists CFDA numbers: 93.242, 93.361, 93.853, and 93.866, corresponding to mental health research, nursing research, neurosciences and neurological disorders research, and aging research.
19) Is cost sharing or matching required?
No. The FOA states that cost sharing/matching is not required, which can reduce financial barriers for applicants.
20) Who is eligible to apply?
Eligibility is broad and includes many U.S.-based entity types, such as public and private institutions of higher education, nonprofits (including with and without 501(c)(3) status), small businesses, for-profit organizations (including those other than small businesses), and a range of government entities (state, county, city/township, special district governments, and independent school districts).
21) Are foreign institutions allowed to apply?
Yes. The FOA explicitly allows applications from foreign institutions.
22) Can faith-based or community-based organizations apply?
Yes. The FOA notes that faith-based and community-based organizations may apply, which can support community-engaged research approaches.
23) Which federal agency sponsors this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
24) When was the FOA posted, and does it have a single deadline?
The record indicates the FOA was originally posted on November 21, 2006, and it had multiple receipt dates rather than a single deadline.
25) Is this FOA still active?
The record indicates an archive date of February 2, 2010. That means this specific announcement was time-limited as listed, even though similar NIH priorities may continue under newer sleep- and insomnia-related funding calls.
26) Where was the full announcement made available?
The full announcement was made available through the NIH grants guide site.
27) Who should be contacted for technical access or linking issues related to the listing?
The listing directs technical access and linking issues to the NIH Office of Extramural Research (OER) webmaster.
Browse more opportunities from the same category: Education Health
Next opportunity: Drug Discovery for Nervous System Disorders (R01)
Previous opportunity: Research on Mind Body Interactions and Health (R01)
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for PA 07 047
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (PA 07 047) also looked into and applied for these:
| Funding Opportunity |
|---|
| Drug Discovery for Nervous System Disorders (R01) Apply for PAR 07 048 Funding Number: PAR 07 048 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research On The Reduction And Prevention Of Suicidality (R01) Apply for PA 07 079 Funding Number: PA 07 079 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Risk Factors For Psychopathology Using Existing Data Sets (R01) Apply for PA 07 082 Funding Number: PA 07 082 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R01) Apply for PAR 07 086 Funding Number: PAR 07 086 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| HIV Infection Of The Central Nervous System (R01) Apply for PA 07 089 Funding Number: PA 07 089 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| HIV/AIDS, Severe Mental Illness And Homelessness (R01) Apply for PA 07 090 Funding Number: PA 07 090 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Prioritizing Molecular Targets for Cancer Prevention with Nutritional Combinations (R01) Apply for PA 07 100 Funding Number: PA 07 100 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Research on Rural Mental Health and Drug Abuse Disorders (R01) Apply for PA 07 103 Funding Number: PA 07 103 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Behavioral and Integrative Treatment Development Program (R01) Apply for PA 07 111 Funding Number: PA 07 111 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network (CTN) (R01) Apply for PA 07 113 Funding Number: PA 07 113 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Pathophysiology of Bisphosphonates associated Osteonecrosis of the Jaw (R01) Apply for PA 07 132 Funding Number: PA 07 132 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| The Development Of Frontal Cortex And Limbic System And Their Roles In Drug Abuse Or Mental Health (R01) Apply for PA 07 121 Funding Number: PA 07 121 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Sarcoidosis Research into the Cause of Multi organ Disease and Clinical Strategies for Therapy (R01) Apply for PA 07 136 Funding Number: PA 07 136 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Building Translational Research in Integrative Behavioral Science (R01) Apply for PAR 07 155 Funding Number: PAR 07 155 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Functional Genetics And Genomics Of Drug Addiction (R03) Apply for PA 07 168 Funding Number: PA 07 168 Agency: National Institutes of Health Category: Education Health Funding Amount: $50,000 |
| Functional Genetics and Genomics of Drug Addiction (R21) Apply for PA 07 167 Funding Number: PA 07 167 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Functional Genetics And Genomics Of Drug Addiction (R01) Apply for PA 07 166 Funding Number: PA 07 166 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Pathogenesis And Treatment Of Lymphedema And Lymphatic Diseases (R01) Apply for PA 07 165 Funding Number: PA 07 165 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Studies of Energy Balance and Cancer in Humans (R01) Apply for PA 07 176 Funding Number: PA 07 176 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Memory T Lymphocytes in Cancer Immunology (R01) Apply for PA 07 255 Funding Number: PA 07 255 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "PA 07 047", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.