Opportunity Information: Apply for PA 09 122
Apply for PA 09 122
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Research on Clinical Decision Making in People with or at Risk for Life Threatening Illness (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361 Nursing Research 93.399 Cancer Control.
- This funding opportunity was created on Mar 9, 2009 and posted on Mar 9, 2009.
- Applicants must submit their applications by May 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Private institutions of higher education Public and State controlled institutions of higher education Small businesses City or township governments Independent school districts Public housing authorities/Indian housing authorities For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) State governments County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NIH funding opportunity "Research on Clinical Decision Making in People with or at Risk for Life Threatening Illness (R01)" (Funding Opportunity Number PA-09-122) is a discretionary grant program sponsored by the National Institute of Nursing Research (NINR) and the National Cancer Institute (NCI). Its central goal is to stimulate rigorous research that explains and improves how people make clinical and health-related decisions when they are at risk for, or living with, illnesses that can be fatal if untreated but may become chronic or even curable when detected and managed early. The FOA frames "life threatening illness" broadly across conditions and trajectories, using examples such as HIV infection (often chronic for years with treatment) and early-stage breast cancer (potentially curable if addressed promptly). The emphasis is on understanding decision making as a process that unfolds over time, rather than a single moment, and on generating evidence that can inform better support for patients and families as they face high-stakes choices.
A key feature of this opportunity is its wide view of what counts as clinical decision making. It explicitly includes decisions that occur across the full continuum of risk and illness: from adopting preventive behaviors and seeking screening, to pursuing diagnostic testing, to selecting among treatment approaches, to participating in clinical research, and ultimately to choices related to end-of-life care. The announcement highlights example decision points such as joining an HIV vaccine clinical trial, undergoing genetic testing for a disorder, choosing active treatment versus watchful waiting (with early-stage prostate cancer as an illustrative case), selecting among multiple therapeutic options, enrolling in a therapeutic clinical trial, and making end-of-life care decisions. In practical terms, this means proposed projects can focus on many different types of decision contexts, as long as the core scientific aim is to study the processes by which individuals confronted with serious illness risk or diagnosis weigh information, values, uncertainty, burdens, and benefits to arrive at decisions.
The mechanism of support is the NIH R01 research project grant, which typically funds mature, hypothesis-driven or well-developed programs of research that can produce substantial, generalizable knowledge. This FOA is also noted to run in parallel with a companion announcement of the same scientific scope that uses the R21 mechanism (PAR-09-121), which is commonly oriented toward exploratory or early-stage work. Applicants, therefore, would generally choose PA-09-122 if they have a more fully developed research plan suitable for an R01-scale project, while the R21 companion would be a better fit for earlier or higher-risk preliminary lines of investigation. The activity categories associated with the funding include Education and Health, and the program is tied to CFDA numbers 93.361 (Nursing Research) and 93.399 (Cancer Control), reflecting the co-sponsorship and the interdisciplinary reach across nursing science, cancer control, and broader clinical decision science.
Eligibility for this FOA is expansive, spanning many organization types. Eligible applicants include public and private institutions of higher education, public and state-controlled universities, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), small businesses, for-profit organizations (including those other than small businesses), and a wide range of government entities such as state, county, city or township governments, special district governments, and public housing authorities. The FOA also specifies eligibility for tribal governments and tribal organizations, including federally recognized tribes and other tribal entities, as well as faith-based and community-based organizations. Importantly, it includes various institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and it allows non-U.S. entities (foreign organizations) and regional organizations, as well as U.S. territories or possessions. No cost sharing or matching requirement is indicated, meaning applicants are not required to provide a financial match as a condition of the award.
From an administrative standpoint, the FOA was posted and created on March 9, 2009, with an original and current closing date of May 7, 2012, and an archive date of June 7, 2012, indicating that the announcement is no longer active for new submissions under that specific listing. The sponsoring agency is the National Institutes of Health, and the full announcement was made available through the NIH Grants Guide. For technical issues accessing the announcement or linking to it, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, and the archived program page is referenced at http://grants.nih.gov/grants/guide/pa-files/PA-09-122.html.
Frequently Asked Questions (FAQs)
What is the name of this NIH funding opportunity?
The funding opportunity is titled "Research on Clinical Decision Making in People with or at Risk for Life Threatening Illness (R01)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA-09-122.
Which NIH institutes sponsor this grant opportunity?
This discretionary grant program is sponsored by the National Institute of Nursing Research (NINR) and the National Cancer Institute (NCI).
What is the main purpose or goal of PA-09-122?
The central goal is to stimulate rigorous research that explains and improves how people make clinical and health-related decisions when they are at risk for, or living with, illnesses that can be fatal if untreated but may become chronic or even curable when detected and managed early.
How does the opportunity define "life threatening illness"?
The FOA frames "life threatening illness" broadly across conditions and illness trajectories. Examples mentioned include HIV infection (often chronic for years with treatment) and early-stage breast cancer (potentially curable if addressed promptly).
Does this FOA focus on a single decision point or on decision making over time?
The emphasis is on decision making as a process that unfolds over time, rather than as a single moment, with the intent to generate evidence that can inform better support for patients and families facing high-stakes choices.
What kinds of decisions are considered "clinical decision making" under this announcement?
The FOA takes a wide view of clinical decision making. It includes decisions across the full continuum of risk and illness, from adopting preventive behaviors and seeking screening, to pursuing diagnostic testing, to selecting among treatment approaches, to participating in clinical research, and to decisions related to end-of-life care.
What are examples of decision points mentioned in the FOA?
Examples include joining an HIV vaccine clinical trial, undergoing genetic testing for a disorder, choosing active treatment versus watchful waiting (illustrated with early-stage prostate cancer), selecting among multiple therapeutic options, enrolling in a therapeutic clinical trial, and making end-of-life care decisions.
Can projects focus on prevention and screening decisions, or only on treatment decisions?
Projects can focus on prevention and screening decisions as well as later decisions. The FOA explicitly includes decisions from preventive behaviors and screening through diagnosis, treatment selection, research participation, and end-of-life care.
What grant mechanism is used for this opportunity?
The mechanism of support is the NIH R01 research project grant.
What does it imply that this is an R01 opportunity?
Based on the description provided, the R01 is intended to support mature, hypothesis-driven or well-developed programs of research that can produce substantial, generalizable knowledge.
Is there a related or companion opportunity for exploratory research?
Yes. The FOA is noted to run in parallel with a companion announcement of the same scientific scope using the R21 mechanism (PAR-09-121), which is commonly oriented toward exploratory or early-stage work.
How should an applicant choose between PA-09-122 (R01) and the companion R21 opportunity?
The provided description suggests choosing PA-09-122 if you have a more fully developed research plan suitable for an R01-scale project, while the R21 companion (PAR-09-121) is described as a better fit for earlier or higher-risk preliminary lines of investigation.
What activity categories are associated with this funding opportunity?
The activity categories associated with the funding include Education and Health.
Which CFDA numbers are tied to this program?
The FOA is tied to CFDA 93.361 (Nursing Research) and 93.399 (Cancer Control).
What types of organizations are eligible to apply?
Eligibility is broad and includes (as listed in the provided information): public and private institutions of higher education; public and state-controlled universities; nonprofits (including 501(c)(3) and certain non-501(c)(3) entities); small businesses; for-profit organizations (including those other than small businesses); and government entities such as state, county, city or township governments, special district governments, and public housing authorities.
Are tribal governments and tribal organizations eligible?
Yes. The FOA specifies eligibility for tribal governments and tribal organizations, including federally recognized tribes and other tribal entities.
Are faith-based and community-based organizations eligible?
Yes. The FOA includes faith-based and community-based organizations among eligible applicants.
Are minority-serving institutions specifically included as eligible applicants?
Yes. The FOA includes institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.
Can foreign (non-U.S.) organizations apply?
Yes. The FOA allows non-U.S. entities (foreign organizations) and regional organizations, and it also allows U.S. territories or possessions.
Is cost sharing or matching required?
No cost sharing or matching requirement is indicated. The provided information states that applicants are not required to provide a financial match as a condition of the award.
When was this FOA posted and created?
The FOA was posted and created on March 9, 2009.
What was the closing date for this opportunity?
The original and current closing date listed is May 7, 2012.
Is PA-09-122 still active for new submissions?
No. The archive date is June 7, 2012, and the information indicates the announcement is no longer active for new submissions under that specific listing.
Which agency is responsible for this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
Where was the full announcement made available?
The full announcement was made available through the NIH Grants Guide.
Where can the archived program page be found?
The archived program page is referenced at http://grants.nih.gov/grants/guide/pa-files/PA-09-122.html.
Who should be contacted for technical issues accessing the announcement or links?
For technical issues accessing the announcement or linking to it, the listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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| Pilot and Feasibility Studies in Preparation for Drug Abuse Prevention Trials (R34) Apply for PA 09 146 Funding Number: PA 09 146 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Economic Studies of Health Insurance Coverage on Drug Abuse Treatment Availability, Access, Costs, and Quality (R01) Apply for RFA DA 10 004 Funding Number: RFA DA 10 004 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
| Studies of Energy Balance and Cancer in Humans (R01) Apply for PA 09 148 Funding Number: PA 09 148 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Studies of Energy Balance and Cancer in Humans (R21) Apply for PA 09 149 Funding Number: PA 09 149 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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| NLM Applied Informatics Grants (G08) Apply for RFA LM 09 001 Funding Number: RFA LM 09 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $150,000 |
| Developmental Research in Cancer Prognosis and Prediction (R21) Apply for PA 09 158 Funding Number: PA 09 158 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Developmental Research in Cancer Prognosis and Prediction (R33) Apply for PA 09 159 Funding Number: PA 09 159 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Exploratory/Developmental Grants Program for Basic Cancer Research in Cancer Health Disparities (R21) Apply for PAR 09 160 Funding Number: PAR 09 160 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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