Opportunity Information: Apply for PA 11 182
Apply for PA 11 182
- The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Research on Ethical Issues in Biomedical, Social, and Behavioral Research (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.361 Nursing Research 93.395 Cancer Treatment Research 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Dec 13, 2013 and posted on Mar 24, 2011.
- Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) State governments Private institutions of higher education County governments Small businesses Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Special district governments For profit organizations other than small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The NIH funding opportunity PA-11-182, titled "Research on Ethical Issues in Biomedical, Social, and Behavioral Research (R21)," supports exploratory and developmental projects that tackle pressing bioethics questions arising from biomedical, social, and behavioral research. It uses the NIH R21 mechanism, which is designed for early-stage, high-impact, or novel work where investigators may be piloting concepts, developing frameworks, testing feasibility, or generating preliminary data to support a larger future study. The overall aim is to encourage investigator-initiated research that clarifies, analyzes, or helps resolve ethical challenges that come up in the kinds of research portfolios funded by the participating NIH Institutes and Centers, with an emphasis on issues considered "high priority" from a bioethics standpoint.
A key feature of this announcement is its cross-cutting nature: it is meant to apply broadly across NIH-supported research areas, including but not limited to environmental health, oral health, genomics, communication disorders, complementary and integrative health, mental health, alcohol and drug use, technological innovations for health, nursing, cancer, cardiovascular and lung diseases, neuroscience, infectious diseases, child health and development, and aging. The Office of Behavioral and Social Sciences Research (OBSSR) is involved in the FOA to strengthen attention to behavioral and social dimensions of health and illness, but applicants should understand that actual grant awards are made by the participating NIH Institutes and Centers, not OBSSR acting alone. In practical terms, this means a project should fit within the mission and interests of one or more participating NIH components, because those are the entities that will ultimately provide the direct support.
The announcement is positioned for research that examines ethical issues embedded in how studies are designed, conducted, and translated into practice. While the FOA text provided here does not list specific topic areas, the scope typically includes questions like protecting human participants in emerging or complex study designs, handling consent and autonomy challenges, managing privacy and data sharing risks (especially in genomics and large data environments), addressing fairness and inclusion in recruitment, considering community and cultural impacts, managing conflicts of interest, and dealing with ethical issues in translating research findings into clinical or public settings. Projects can be conceptual, empirical, or mixed-method, as long as they advance understanding of ethical problems that are directly tied to biomedical, social, or behavioral research and can inform policy, guidance, or best practices.
In terms of funding structure, the FOA is a discretionary grant opportunity with no cost sharing or matching requirement. The listed award ceiling is $200,000, consistent with the R21 emphasis on smaller, time-limited exploratory work rather than large-scale, multi-year trials. Because it is an R21, reviewers generally expect a strong rationale and a clear plan, but they also recognize that applicants may be developing new approaches and may not yet have extensive preliminary data, as long as the project is well-justified and feasible.
Eligibility is broad and intentionally inclusive. Eligible applicants include public and private institutions of higher education, nonprofit and for-profit organizations (including small businesses), state, county, city, township, and special district governments, independent school districts, public housing authorities/Indian housing authorities, and tribal governments and organizations. The FOA also explicitly welcomes a wide range of institutions and communities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions. Importantly, foreign organizations and non-U.S. components of U.S. organizations are allowed, which can be especially relevant for ethics research that benefits from international comparisons, global health contexts, or cross-cultural perspectives, provided the project aligns with NIH requirements and the priorities of the participating Institutes and Centers.
From an administrative standpoint, the opportunity was posted March 24, 2011, with an original closing date of May 7, 2014, and a final closing date of May 7, 2015, after which it was archived June 7, 2015. The CFDA numbers attached to the FOA indicate the breadth of NIH program areas that could align with bioethics topics, and applicants would typically use those mission alignments to choose the most appropriate Institute or Center and tailor their application accordingly.
The official announcement and application details were hosted through the NIH grants system at http://grants.nih.gov/grants/guide/pa-files/PA-11-182.html. For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, which is mainly for troubleshooting access and linking problems rather than programmatic scientific questions.
Frequently Asked Questions (FAQs) - NIH PA-11-182 (R21): Research on Ethical Issues in Biomedical, Social, and Behavioral Research
What is PA-11-182?
PA-11-182 is an NIH funding opportunity announcement titled "Research on Ethical Issues in Biomedical, Social, and Behavioral Research (R21)." It supports exploratory and developmental research projects that address pressing bioethics questions arising from biomedical, social, and behavioral research.
What type of grant mechanism does this opportunity use?
This opportunity uses the NIH R21 mechanism, which is designed for early-stage, high-impact, or novel projects. R21 projects often involve piloting ideas, developing conceptual or analytic frameworks, testing feasibility, or generating preliminary data that can support a larger future study.
What is the main goal of this funding opportunity?
The goal is to encourage investigator-initiated research that clarifies, analyzes, or helps resolve ethical challenges that arise within research areas funded by participating NIH Institutes and Centers, with an emphasis on bioethics issues considered "high priority."
What kinds of ethical issues are within scope for projects under this FOA?
Based on the description provided, projects may address ethical issues embedded in how studies are designed, conducted, and translated into practice. Examples include protecting human participants in emerging or complex study designs; consent and autonomy challenges; privacy and data sharing risks (especially in genomics and large data settings); fairness and inclusion in recruitment; community and cultural impacts; conflicts of interest; and ethical issues in translating research findings into clinical or public settings.
Does the FOA require a specific research approach (conceptual vs. empirical)?
No. Projects can be conceptual, empirical, or mixed-method, as long as they advance understanding of ethical problems directly tied to biomedical, social, or behavioral research and can inform policy, guidance, or best practices.
Is this opportunity limited to a particular NIH scientific area?
No. A key feature is that it is cross-cutting and intended to apply broadly across NIH-supported research areas. The description notes alignment with many areas, including (but not limited to) environmental health, oral health, genomics, communication disorders, complementary and integrative health, mental health, alcohol and drug use, technological innovations for health, nursing, cancer, cardiovascular and lung diseases, neuroscience, infectious diseases, child health and development, and aging.
What is OBSSR's role in this funding opportunity?
The Office of Behavioral and Social Sciences Research (OBSSR) is involved to strengthen attention to behavioral and social dimensions of health and illness. However, grant awards are made by the participating NIH Institutes and Centers, not OBSSR acting alone.
Who actually funds and makes awards under this FOA?
Awards are made by the participating NIH Institutes and Centers. As described, applicants should ensure their project fits within the mission and interests of one or more participating NIH components, because those are the entities that ultimately provide direct support.
Is cost sharing or matching required?
No. The opportunity is described as discretionary and states there is no cost sharing or matching requirement.
What is the maximum award amount mentioned for this opportunity?
The listed award ceiling is $200,000, consistent with the R21 focus on smaller, time-limited exploratory work.
Is preliminary data required for an R21 application under this FOA?
The description indicates that reviewers generally recognize R21 applications may involve new approaches and may not yet have extensive preliminary data, as long as the project is well-justified, feasible, and has a strong rationale and clear plan.
Which organizations are eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; nonprofit and for-profit organizations (including small businesses); state, county, city, township, and special district governments; independent school districts; public housing authorities/Indian housing authorities; and tribal governments and organizations.
Are specific institution types explicitly encouraged or welcomed?
Yes. The FOA explicitly welcomes a wide range of institutions and communities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions.
Are foreign organizations allowed to apply?
Yes. Foreign organizations and non-U.S. components of U.S. organizations are allowed, which may be relevant for ethics research involving international comparisons, global health contexts, or cross-cultural perspectives, provided the work aligns with NIH requirements and the priorities of participating Institutes and Centers.
When was this funding opportunity posted, and what is its status now?
The opportunity was posted on March 24, 2011. It had an original closing date of May 7, 2014, and a final closing date of May 7, 2015. It was archived on June 7, 2015.
Where can the official FOA announcement be found?
The official announcement and application details were hosted through the NIH grants system at http://grants.nih.gov/grants/guide/pa-files/PA-11-182.html.
Who is listed as the contact for access or technical issues with the FOA page?
For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV. This contact is described as being for troubleshooting access and linking problems rather than programmatic or scientific questions.
How should applicants think about choosing an NIH Institute or Center for mission fit?
The description notes that the CFDA numbers attached to the FOA indicate a broad range of NIH program areas that could align with bioethics topics. Applicants would typically use those mission alignments to choose the most appropriate participating Institute or Center and tailor the application accordingly.
What general kinds of outcomes does NIH appear to want from supported projects?
Projects should advance understanding of ethical problems in biomedical, social, or behavioral research and be positioned to inform policy, guidance, or best practices related to research design, conduct, or translation into clinical or public settings.
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Applicants also applied for:
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