Opportunity Information: Apply for RFA RR 09 004

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Research on Integrity in Collaborative Research (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.389 National Center for Research Resources 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Oct 30, 2008 and posted on Oct 30, 2008.
  • Applicants must submit their applications by Mar 17, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $850,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) State governments Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Independent school districts County governments Small businesses Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for RFA RR 09 004

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Opportunity Summary:

The Research on Integrity in Collaborative Research (R21) funding opportunity (RFA RR 09-004) was issued by the National Institutes of Health (NIH), led by the National Center for Research Resources (NCRR) in partnership with the Office of Research Integrity (ORI). Its main goal is to support research that examines how collaboration in research settings influences research integrity. The focus is specifically on integrity issues that arise when people work together across labs, departments, institutions, or disciplines, including the day-to-day interactions and shared activities that can either strengthen or undermine responsible research practices.

This announcement uses the NIH R21 exploratory/developmental grant mechanism, which is designed for early-stage, innovative, or high-impact ideas where the evidence base is still limited. In other words, it is meant to fund projects that may not yet have extensive preliminary data but are positioned to identify key problem areas, generate foundational findings, and open up new lines of inquiry about integrity challenges in collaborative research environments. Applicants are expected to propose studies that push beyond routine descriptions of misconduct and instead test fresh concepts, challenge prevailing assumptions, or tackle major barriers to understanding why deviations from accepted standards happen in collaborative contexts.

To be responsive, applications must directly address how collaborative interactions and/or activities affect research integrity in at least one of several priority areas. These areas include clarifying community norms and standards (for example, how expectations about authorship, data sharing, or supervision are formed and enforced in teams), evaluating the effectiveness of self-regulation (such as internal lab controls, peer accountability, and institutional policies), analyzing societal, organizational, group, or individual factors that shape integrity either positively or negatively (including incentives, power dynamics, training, leadership, competition, or resource constraints), or studying the impacts of failing to adhere to accepted codes of conduct. The emphasis is on understanding the multiple factors that influence integrity in real collaborative settings, including how pressures and structures within teams can contribute to questionable research practices or, conversely, how strong collaborative norms can prevent them.

The research supported under this opportunity must be clearly relevant to biomedical research, behavioral health sciences, or health services research. Applicants are encouraged to align their topics with ORI priorities and with the interests of NIH Institutes and Centers, meaning proposals should not be abstract ethics discussions but should connect to practical integrity concerns in health-related research fields where collaboration is common and consequential.

For funding, NIH anticipated a total FY2009 investment of about $850,000 in total costs, with the intention to make approximately two to three new R21 awards. The listed award ceiling is $200,000. As with many federal research announcements, awards were contingent on the availability of funds and on receiving a sufficient number of high-quality, meritorious applications.

Eligibility was broad and included many types of applicants across the public, private, nonprofit, and governmental sectors. Eligible entities included public and private institutions of higher education, nonprofits (both 501(c)(3) and non-501(c)(3)), for-profit organizations (including small businesses), state and local governments, tribal governments and tribal organizations, independent school districts, public housing authorities/Indian housing authorities, and other specialized categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, U.S. territories or possessions, regional organizations, and even non-U.S. (foreign) entities.

Key timing details for this specific announcement were: it was posted on October 30, 2008, and the application deadline (original and current) was March 17, 2009, with an archive date of April 17, 2009. The full announcement was hosted through the NIH grants portal at http://grants.nih.gov/grants/guide/rfa-files/RFA-RR-09-004.html, and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

Frequently Asked Questions (FAQs)

What is the name and identifier of this funding opportunity?

The opportunity is titled Research on Integrity in Collaborative Research (R21) and is identified as RFA RR 09-004.

Which agencies or offices issued and led this announcement?

This funding opportunity was issued by the National Institutes of Health (NIH), led by the National Center for Research Resources (NCRR), in partnership with the Office of Research Integrity (ORI).

What is the main goal of this RFA?

The main goal is to support research that examines how collaboration in research settings influences research integrity, including the day-to-day interactions and shared activities that can strengthen or undermine responsible research practices.

What types of collaboration-related settings does the RFA emphasize?

The focus is on integrity issues that arise when people work together across labs, departments, institutions, or disciplines, especially where collaborative interactions and shared work processes affect integrity outcomes.

What grant mechanism is being used?

This announcement uses the NIH R21 exploratory/developmental grant mechanism.

What does the R21 mechanism imply about project stage and preliminary data?

The R21 mechanism is intended for early-stage, innovative, or potentially high-impact ideas where the evidence base is still limited. Projects may be appropriate even if they do not yet have extensive preliminary data, as long as they are positioned to identify key problem areas and generate foundational findings.

What kind of research approach is the RFA looking for (beyond general misconduct descriptions)?

Applicants are expected to go beyond routine descriptions of misconduct by testing fresh concepts, challenging prevailing assumptions, or tackling major barriers to understanding why deviations from accepted standards occur in collaborative contexts.

What must an application do to be considered responsive to the RFA?

To be responsive, an application must directly address how collaborative interactions and/or activities affect research integrity in at least one of the specified priority areas described in the announcement.

What are the priority areas highlighted in this RFA?

The RFA highlights priority areas that include: (1) clarifying community norms and standards; (2) evaluating the effectiveness of self-regulation; (3) analyzing societal, organizational, group, or individual factors that shape integrity; and (4) studying impacts of failing to adhere to accepted codes of conduct.

What does "clarifying community norms and standards" mean in this context?

It refers to studying how expectations are formed and enforced within research teams, including norms related to authorship, data sharing, and supervision in collaborative work.

What does the RFA mean by "effectiveness of self-regulation"?

It includes examining how integrity is supported (or not) through mechanisms like internal lab controls, peer accountability, and institutional policies in collaborative research environments.

What kinds of factors shaping integrity are mentioned?

The announcement points to factors that can influence integrity positively or negatively, including incentives, power dynamics, training, leadership, competition, and resource constraints.

Does the RFA focus only on problems, or also on protective factors?

It focuses on both. The RFA emphasizes understanding how pressures and structures can contribute to questionable practices, and also how strong collaborative norms can help prevent deviations from accepted standards.

What fields must the proposed research be relevant to?

The supported research must be clearly relevant to biomedical research, behavioral health sciences, or health services research.

Are purely abstract ethics discussions appropriate for this RFA?

The announcement indicates proposals should not be purely abstract ethics discussions. They should connect to practical integrity concerns in health-related research fields where collaboration is common and consequential.

Is alignment with ORI priorities and NIH Institutes and Centers encouraged?

Yes. Applicants are encouraged to align topics with ORI priorities and with the interests of relevant NIH Institutes and Centers.

How much total funding did NIH anticipate for FY2009 under this announcement?

NIH anticipated a total FY2009 investment of about $850,000 in total costs for this opportunity.

How many awards did NIH intend to make?

NIH intended to make approximately two to three new R21 awards.

What is the listed award ceiling?

The listed award ceiling is $200,000.

Were awards guaranteed?

No. Awards were contingent on the availability of funds and on receiving a sufficient number of high-quality, meritorious applications.

Who was eligible to apply?

Eligibility was broad and included applicants across the public, private, nonprofit, and governmental sectors, including U.S. and non-U.S. entities as described in the announcement.

Are universities and colleges eligible?

Yes. Eligible entities include public and private institutions of higher education, and also several special institutional categories (for example, HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and TCCUs).

Are nonprofit organizations eligible?

Yes. Eligible applicants include nonprofits that are 501(c)(3) and non-501(c)(3).

Are for-profit organizations eligible?

Yes. Eligible applicants include for-profit organizations, including small businesses.

Are government entities eligible?

Yes. Eligible entities include state and local governments, tribal governments and tribal organizations, independent school districts, and public housing authorities/Indian housing authorities, among other categories.

Are faith-based or community-based organizations eligible?

Yes. The eligibility list includes faith-based and community-based organizations.

Are U.S. territories or possessions eligible?

Yes. The eligibility list includes U.S. territories or possessions.

Are foreign (non-U.S.) entities eligible?

Yes. The announcement explicitly includes non-U.S. (foreign) entities among eligible applicants.

When was this funding opportunity posted?

The announcement was posted on October 30, 2008.

What was the application deadline?

The application deadline (original and current) listed in the announcement was March 17, 2009.

When was the archive date for this RFA?

The archive date listed was April 17, 2009.

Where could applicants find the full announcement?

The full announcement was hosted on the NIH grants portal at: http://grants.nih.gov/grants/guide/rfa-files/RFA-RR-09-004.html

Where were technical access issues directed?

Technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

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