Opportunity Information: Apply for PA 12 111

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Research on the Health of LGBTI Populations R01" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.307 Minority Health and Health Disparities Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
  • This funding opportunity was created on Feb 23, 2012 and posted on Feb 23, 2012.
  • Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public housing authorities/Indian housing authorities State governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Special district governments County governments For profit organizations other than small businesses Private institutions of higher education City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The NIH funding opportunity titled "Research on the Health of LGBTI Populations R01" (Funding Opportunity Number PA 12-111) was a discretionary NIH grant program using the R01 mechanism to support a wide range of research aimed at improving the scientific understanding of health in lesbian, gay, bisexual, transgender, intersex, and related populations (referred to in the announcement as LGBTI populations). The main purpose of the announcement was to encourage studies that clarify health status, health risks, and health outcomes in these communities, and to strengthen the evidence base for interventions, clinical care, and health services that are effective and appropriate for LGBTI populations. A key theme is that NIH viewed these populations as having potentially distinctive health risk profiles while also being historically understudied, so the announcement was intended to help address gaps created by limited prior research attention.

This FOA invited proposals across multiple research domains, reflecting the fact that LGBTI health questions span biology, psychology, social context, clinical care, and public systems. Applicants could propose basic research (for example, studies that build foundational knowledge relevant to health), social and behavioral research (such as how stigma, discrimination, social support, or identity development relate to health behaviors and outcomes), clinical research (including prevention, diagnosis, treatment, or management of conditions affecting LGBTI individuals), and health services research (such as access to care, quality of care, provider training, patient-provider communication, and system-level barriers). The announcement emphasized alignment with the missions of the participating NIH Institutes and Centers, meaning proposed topics could connect to a broad set of health areas rather than being limited to one disease or discipline.

The breadth of participating program areas is reflected in the listed CFDA numbers, which include research related to mental health; alcohol use; drug abuse and addiction; minority health and health disparities; multiple cancer research areas (cause and prevention, detection and diagnosis, treatment, biology, and control); arthritis and musculoskeletal and skin diseases; microbiology and infectious diseases; child health and human development; aging; and research related to deafness and communication disorders. In practical terms, that meant the FOA could support projects examining many different outcomes and life stages, from child and adolescent development to adult and older adult health, and across conditions ranging from behavioral health and substance use to infectious disease and cancer control, as long as the work was relevant to LGBTI populations and fit within NIH program priorities.

In terms of eligibility, the opportunity was intentionally broad and open to a wide range of organizations. Eligible applicants included state, county, city or township, and special district governments; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; public and private institutions of higher education; independent school districts; nonprofit organizations (including 501(c)(3) nonprofits and certain nonprofits without 501(c)(3) status); small businesses; and for-profit organizations other than small businesses. The eligibility language also explicitly included a variety of mission-driven and capacity-building institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Tribally Controlled Colleges and Universities (TCCUs), as well as faith-based and community-based organizations, regional organizations, and eligible federal agencies. Importantly, the FOA allowed non-U.S. entities (foreign institutions) to apply, permitted non-U.S. components of U.S. organizations, and allowed foreign components as defined by NIH policy. There was no cost sharing or matching requirement, which typically lowers barriers for applicants that do not have significant non-federal resources to contribute.

From an administrative standpoint, the FOA was posted and created on February 23, 2012. The original and current closing date listed was May 7, 2015, and the opportunity was archived on June 7, 2015, meaning it is no longer an open competition under that specific announcement. The sponsoring agency was the National Institutes of Health, and the full announcement was made available through the NIH grants guide at the link provided in the notice. For access or technical problems, NIH directed applicants to contact the NIH Office of Extramural Research (OER) webmaster via the provided email address.

Overall, this R01 opportunity functioned as a targeted encouragement from NIH to expand rigorous, fundable research focused on LGBTI populations, especially research that could clarify why certain health disparities exist, identify modifiable risk and protective factors, and translate findings into better interventions, clinical practices, and health services. The central idea was not only to document disparities, but also to build the science needed to improve health outcomes and care effectiveness for LGBTI individuals across settings and across the lifespan.

FAQs: NIH Funding Opportunity "Research on the Health of LGBTI Populations R01" (PA-12-111)

What is this NIH funding opportunity?

This was an NIH discretionary grant program titled "Research on the Health of LGBTI Populations R01" that used the R01 grant mechanism. Its goal was to support research that improves scientific understanding of health in lesbian, gay, bisexual, transgender, intersex, and related populations (referred to in the announcement as LGBTI populations).

What was the main purpose of PA-12-111?

The purpose was to encourage studies that clarify health status, health risks, and health outcomes in LGBTI communities, and to strengthen the evidence base for interventions, clinical care, and health services that are effective and appropriate for LGBTI populations.

Why did NIH issue this announcement?

A central theme of the announcement was that LGBTI populations may have distinctive health risk profiles while also being historically understudied. NIH intended this opportunity to help address gaps created by limited prior research attention and to expand rigorous, fundable research focused on LGBTI health.

What kinds of research topics were encouraged?

The announcement encouraged a wide range of research aimed at understanding and improving LGBTI health, including work that clarifies why certain health disparities exist, identifies modifiable risk and protective factors, and translates findings into improved interventions, clinical practices, and health services.

What research domains could applicants propose under this FOA?

Proposals could fall across multiple domains, including basic research, social and behavioral research, clinical research, and health services research. The FOA reflected that LGBTI health questions can span biology, psychology, social context, clinical care, and public systems.

What is an example of basic research that could fit this FOA?

The announcement noted basic research as eligible in scope, including studies that build foundational knowledge relevant to health in LGBTI populations.

What is an example of social and behavioral research that could fit?

Examples included research examining how stigma, discrimination, social support, or identity development relate to health behaviors and health outcomes for LGBTI populations.

What types of clinical research were within scope?

The FOA described clinical research as within scope, including research on prevention, diagnosis, treatment, or management of conditions affecting LGBTI individuals.

What types of health services research were within scope?

Health services research topics mentioned included access to care, quality of care, provider training, patient-provider communication, and system-level barriers affecting LGBTI populations.

Did the FOA limit projects to one disease area or discipline?

No. The FOA emphasized alignment with the missions of participating NIH Institutes and Centers, which meant topics could connect to a broad set of health areas rather than being limited to a single disease or discipline.

Which NIH program areas were reflected in the FOA?

The opportunity listed multiple CFDA numbers indicating breadth across program areas, including mental health; alcohol use; drug abuse and addiction; minority health and health disparities; multiple cancer research areas (cause and prevention, detection and diagnosis, treatment, biology, and control); arthritis and musculoskeletal and skin diseases; microbiology and infectious diseases; child health and human development; aging; and deafness and communication disorders.

What does the list of CFDA areas suggest about allowable outcomes and populations?

It suggests the FOA could support projects examining many different outcomes and life stages, from child and adolescent development to adult and older adult health, and across conditions ranging from behavioral health and substance use to infectious disease and cancer control, as long as the work was relevant to LGBTI populations and fit NIH program priorities.

Who was eligible to apply?

Eligibility was broad. Eligible applicants included state, county, city or township, and special district governments; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; public and private institutions of higher education; independent school districts; nonprofit organizations (including 501(c)(3) nonprofits and certain nonprofits without 501(c)(3) status); small businesses; and for-profit organizations other than small businesses.

Were specific institution types explicitly included?

Yes. The eligibility language explicitly included Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Tribally Controlled Colleges and Universities (TCCUs). It also included faith-based and community-based organizations, regional organizations, and eligible federal agencies.

Could foreign (non-U.S.) organizations apply?

Yes. The FOA allowed non-U.S. entities (foreign institutions) to apply, permitted non-U.S. components of U.S. organizations, and allowed foreign components as defined by NIH policy.

Was cost sharing or matching required?

No. The FOA stated there was no cost sharing or matching requirement.

What grant mechanism did NIH use for this opportunity?

This opportunity used the NIH R01 mechanism.

What is the Funding Opportunity Number?

The Funding Opportunity Number was PA-12-111.

When was this FOA created and posted?

The FOA was created and posted on February 23, 2012.

What was the closing date for applications under this announcement?

The original and current closing date listed was May 7, 2015.

Is this funding opportunity still open?

No. The opportunity was archived on June 7, 2015, which means it is no longer an open competition under that specific announcement.

Which agency sponsored this funding opportunity?

The sponsoring agency was the National Institutes of Health (NIH).

Where was the full announcement made available?

The full announcement was made available through the NIH Grants Guide (via the link provided in the notice).

Who should be contacted for access or technical problems related to the FOA?

NIH directed applicants with access or technical problems to contact the NIH Office of Extramural Research (OER) webmaster via the email address provided in the notice.

What was the broader goal beyond documenting disparities?

The FOA emphasized building the science needed to improve health outcomes and care effectiveness for LGBTI individuals across settings and across the lifespan, not only documenting disparities.

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