Opportunity Information: Apply for PA 12 113

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Research on the Health of LGBTI Populations (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.307 Minority Health and Health Disparities Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
  • This funding opportunity was created on Feb 23, 2012 and posted on Feb 23, 2012.
  • Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments For profit organizations other than small businesses Public and State controlled institutions of higher education Special district governments Small businesses City or township governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The NIH Funding Opportunity Announcement (FOA) titled "Research on the Health of LGBTI Populations (R21)" (Funding Opportunity Number PA-12-113) is a discretionary grant program designed to expand scientific knowledge about the health of lesbian, gay, bisexual, transgender, intersex, and related populations. The core purpose is to support studies that improve understanding of LGBTI health status, identify distinctive health risks and protective factors, and strengthen the effectiveness of interventions, health services, and public health approaches for these communities. NIH emphasizes that certain populations may have unique health risk profiles yet remain understudied, and this FOA is intended to help address those gaps by encouraging a wide range of research approaches.

This opportunity uses the NIH R21 mechanism, which is commonly aimed at exploratory or developmental research. Projects supported under an R21 are often early-stage, high-impact, or proof-of-concept efforts that can generate foundational data, test innovative ideas, or open new research directions rather than fund large, long-term programs. The listed award ceiling is $200,000, and there is no cost-sharing or matching requirement, meaning applicants are not required to contribute their own funds as a condition of receiving an award.

The FOA explicitly welcomes multiple types of research, including basic, social, behavioral, clinical, and health services research, as long as the proposed work aligns with the missions of the participating NIH Institutes and Centers. In practice, that means a broad range of topics could fit, from studying biological mechanisms relevant to specific health outcomes, to examining mental health and substance use patterns, to testing interventions that reduce disparities in access to care, to evaluating healthcare delivery models that improve patient experience and outcomes for LGBTI people. The announcement is structured to encourage rigorous research that can clarify where disparities exist, why they occur, and what strategies can reduce them.

The program is associated with a wide set of CFDA numbers that reflect the breadth of NIH components that may support projects under this FOA. These include areas such as mental health (93.242), alcohol research (93.273), drug abuse and addiction (93.279), minority health and health disparities (93.307), multiple cancer research categories (93.393 through 93.399), infectious diseases and microbiology (93.856), child health and human development (93.865), aging (93.866), arthritis and musculoskeletal/skin diseases (93.846), and research related to deafness and communication disorders (93.173). Taken together, these listings signal that applications may focus on many different health conditions or life stages, provided the work is clearly tied to LGBTI health and the scientific mission of the relevant NIH institute or center.

Eligibility for applying is very broad. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (other than small businesses, although small businesses are also listed as eligible), state and local governments (including counties, cities/townships, special districts, and independent school districts), Native American tribal governments and tribal organizations, and public housing authorities/Indian housing authorities. The FOA also highlights eligibility for specific institution types and community-serving entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and faith-based or community-based organizations. Importantly, non-U.S. entities (foreign institutions) are eligible to apply, non-U.S. components of U.S. organizations may apply, and foreign components are allowed as defined by the NIH Grants Policy Statement. This global eligibility can be especially relevant for comparative studies, multinational collaborations, or research in settings where certain LGBTI health issues are especially urgent or under-characterized.

Key administrative details in the source information include a posted and creation date of February 23, 2012, with an original and current closing date of May 7, 2015, and an archive date of June 7, 2015. This indicates the FOA was time-limited and is now archived, which generally means NIH is no longer accepting applications under this specific announcement number and applicants would need to look for reissued, active, or successor FOAs that cover similar scientific priorities.

For those needing the full archived announcement text, the source points to the NIH grants page at http://grants.nih.gov/grants/guide/pa-files/PA-12-113.html. The provided contact path is the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV) for technical issues accessing the announcement or resolving linking problems, which is a practical detail for applicants or researchers trying to retrieve the official requirements, submission instructions, and any special review considerations that were in effect during the active period of the FOA.

Frequently Asked Questions (FAQs)

What is the title and number of this NIH funding opportunity?

The funding opportunity is titled "Research on the Health of LGBTI Populations (R21)" and the Funding Opportunity Number is PA-12-113.

What is the purpose of this FOA?

The purpose is to expand scientific knowledge about the health of lesbian, gay, bisexual, transgender, intersex, and related populations. It is intended to support studies that improve understanding of LGBTI health status, identify distinctive health risks and protective factors, and strengthen the effectiveness of interventions, health services, and public health approaches for these communities.

What kinds of research does the FOA support?

The FOA welcomes a wide range of research approaches, including basic, social, behavioral, clinical, and health services research, as long as the work aligns with the missions of the participating NIH Institutes and Centers and is clearly tied to LGBTI health.

Is this a specific type of NIH grant mechanism?

Yes. This opportunity uses the NIH R21 mechanism, which is commonly used for exploratory or developmental research projects.

What does an R21 typically fund?

R21 awards often support early-stage, proof-of-concept, or high-impact exploratory studies. These projects may generate foundational data, test innovative ideas, or open new research directions, rather than funding large, long-term programs.

What is the maximum award amount listed for this FOA?

The listed award ceiling is $200,000.

Is cost-sharing or matching required?

No. The FOA states there is no cost-sharing or matching requirement, meaning applicants are not required to contribute their own funds as a condition of receiving an award.

What types of topics might fit under this FOA?

The FOA indicates that many topic areas may be appropriate, including studies of biological mechanisms relevant to health outcomes, patterns of mental health and substance use, interventions to reduce disparities in access to care, and evaluations of healthcare delivery models that improve patient experience and outcomes for LGBTI people. The key is that the research is tied to LGBTI health and aligns with an NIH Institute or Center mission.

Why did NIH issue this FOA focused on LGBTI populations?

NIH emphasizes that certain populations may have unique health risk profiles but remain understudied. This FOA is meant to help address those research gaps by encouraging rigorous studies that clarify where disparities exist, why they occur, and what strategies can reduce them.

Which NIH program areas are associated with this FOA (CFDA listings)?

The program is associated with multiple CFDA numbers reflecting a broad NIH scope, including mental health (93.242), alcohol research (93.273), drug abuse and addiction (93.279), minority health and health disparities (93.307), multiple cancer research categories (93.393 through 93.399), infectious diseases and microbiology (93.856), child health and human development (93.865), aging (93.866), arthritis and musculoskeletal/skin diseases (93.846), and deafness and communication disorders (93.173).

Does the wide range of CFDA numbers mean my health topic could be eligible?

The CFDA range signals that applications may focus on many different health conditions or life stages, as long as the proposal is clearly tied to LGBTI health and to the scientific mission of the relevant NIH Institute or Center.

Who is eligible to apply?

Eligibility is broad and includes public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), for-profit organizations, small businesses, state and local governments (including counties, cities/townships, special districts, and independent school districts), Native American tribal governments and tribal organizations, and public housing authorities/Indian housing authorities.

Are community-serving and minority-serving institutions eligible?

Yes. The FOA highlights eligibility for institution types and community-serving entities such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and faith-based or community-based organizations.

Can non-U.S. (foreign) organizations apply?

Yes. Non-U.S. entities (foreign institutions) are eligible to apply. The FOA also allows non-U.S. components of U.S. organizations to apply, and foreign components are allowed as defined by the NIH Grants Policy Statement.

Is this funding opportunity still accepting applications?

No. The information provided indicates the FOA is time-limited and archived. It lists a current closing date of May 7, 2015, and an archive date of June 7, 2015, which generally means NIH is no longer accepting applications under this specific announcement number.

What should applicants do if they want to pursue similar funding now?

Because this FOA is archived, applicants would typically need to look for a reissued, active, or successor NIH funding opportunity announcement that covers similar scientific priorities related to LGBTI health.

Where can I find the full (archived) FOA text?

The archived announcement is available on the NIH grants site at: http://grants.nih.gov/grants/guide/pa-files/PA-12-113.html

Who should I contact if I have technical trouble accessing the archived announcement link?

The provided technical contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV for issues accessing the announcement or resolving linking problems.

When was this FOA posted and when did it close?

The posted/creation date is February 23, 2012. The original and current closing date listed is May 7, 2015. The archive date is June 7, 2015.

Does this FOA limit research to the United States?

No. Based on the eligibility information provided, the FOA permits foreign institutions to apply and allows foreign components, which can support multinational collaborations or comparative studies when relevant to LGBTI health and NIH mission alignment.

Does the FOA specify which LGBTI groups are included?

It explicitly references lesbian, gay, bisexual, transgender, intersex, and related populations.

Does the FOA require a specific research method or discipline?

No specific single method is required based on the information provided. The FOA welcomes basic, social, behavioral, clinical, and health services research approaches, emphasizing rigorous research tied to LGBTI health and NIH Institute/Center missions.

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