Opportunity Information: Apply for PA 11 143

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Research Opportunities in Obstetric Fistula (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Mar 10, 2011 and posted on Mar 10, 2011.
  • Applicants must submit their applications by May 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Small businesses State governments Native American tribal governments (Federally recognized) County governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for PA 11 143

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Opportunity Summary:

The National Institutes of Health (NIH) offered this discretionary grant opportunity, titled "Research Opportunities in Obstetric Fistula (R21)" (Funding Opportunity Number PA-11-143), to support early-stage, exploratory research focused on obstetric fistula as a major maternal health problem in developing countries. The announcement emphasizes generating new knowledge and testing promising approaches that can improve how obstetric fistula is identified, prevented, and treated, while also addressing the broader social and behavioral realities faced by women who are at risk for, or living with, this condition. In practical terms, NIH was looking for research that can strengthen the evidence base around epidemiology (who is affected and why), clinical strategies (diagnosis, management, and outcomes), and social or behavioral interventions (reducing stigma, improving care-seeking, supporting reintegration, and related issues that shape women s lives before and after injury).

A key boundary in the announcement is what it did not intend to fund. This FOA was not designed to pay for or scale up routine service delivery efforts already outlined in World Health Organization (WHO) obstetric fistula program materials, even though it explicitly recognizes that real-world factors like affordability of care, transportation for women in labor, and overall access to obstetric services are central to reducing fistula rates. Instead of funding those delivery-system expansions directly, the FOA sought research projects that complement ongoing programmatic efforts to improve the timeliness and quality of care during labor, delivery, and the postpartum period. The underlying idea is that eliminating fistula requires multiple approaches at once: stronger emergency obstetric care alongside better clinical, social, and behavioral interventions that can prevent injuries, improve treatment success, and reduce the long-term harm to women and children.

The funding mechanism was the NIH R21, which is commonly used for exploratory or developmental studies that may involve pilot testing, proof-of-concept work, feasibility studies, or early evaluations of innovative interventions. The posted and creation date for the opportunity was March 10, 2011, with an original and current closing date of May 7, 2014, and an archive date of June 7, 2014, meaning it is no longer active. The award ceiling listed for the opportunity was $200,000, and there was no cost sharing or matching requirement. The activity category was Health, Income Security and Social Services, and it was associated with CFDA number 93.865 (Child Health and Human Development Extramural Research), reflecting the maternal and child health focus.

Eligibility was broad and included many types of applicants: public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) organizations), for-profit organizations (including small businesses), and multiple levels of government (state, county, city or township, special districts), as well as public housing authorities and independent school districts. The FOA also explicitly welcomed a wide range of additional eligible entities, including historically underrepresented and mission-specific institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. It also allowed non-U.S. entities (foreign organizations), regional organizations, U.S. territories or possessions, and eligible federal agencies, signaling a clear intent to enable research partnerships and studies in settings where obstetric fistula is most prevalent.

Overall, the opportunity was aimed at advancing practical, research-driven solutions to a severe and often stigmatizing childbirth injury by supporting studies that can clarify risk and prevalence, improve clinical approaches to prevention and treatment, and test social and behavioral interventions that address the lived experience of affected women. The full archived announcement was made available through the NIH grants portal (PA-11-143), and NIH provided an Office of Extramural Research (OER) webmaster contact for access or technical linking issues.

Frequently Asked Questions (FAQs)

What is the title and funding opportunity number for this NIH grant?

The opportunity is titled "Research Opportunities in Obstetric Fistula (R21)" and the Funding Opportunity Number is PA-11-143.

Which agency offered this grant opportunity?

This was a discretionary grant opportunity offered by the National Institutes of Health (NIH).

What is the main purpose of this funding opportunity?

The purpose was to support early-stage, exploratory research on obstetric fistula as a major maternal health problem in developing countries. The emphasis is on generating new knowledge and testing promising approaches that improve how obstetric fistula is identified, prevented, and treated, while also addressing key social and behavioral realities faced by women at risk for, or living with, the condition.

What types of research topics did NIH encourage under this FOA?

NIH encouraged research that strengthens the evidence base around:

  • Epidemiology (who is affected and why)
  • Clinical strategies (diagnosis, management, and outcomes)
  • Social and behavioral interventions (reducing stigma, improving care-seeking, supporting reintegration, and other factors shaping women’s lives before and after injury)

Does this opportunity focus only on clinical treatment, or also on social and behavioral aspects?

It includes both. In addition to clinical approaches, it explicitly emphasizes social and behavioral interventions, including stigma reduction, improving care-seeking, and supporting reintegration for women living with obstetric fistula.

What does the R21 funding mechanism mean in this context?

This opportunity used the NIH R21 mechanism, which is typically used for exploratory or developmental studies. That includes projects such as pilot testing, proof-of-concept work, feasibility studies, and early evaluations of innovative interventions.

What is the award ceiling for this opportunity?

The listed award ceiling was $200,000.

Is cost sharing or matching required?

No. The opportunity stated there was no cost sharing or matching requirement.

When was this opportunity posted, and what were the key dates?

The posted/creation date was March 10, 2011. The original and current closing date was May 7, 2014. The archive date was June 7, 2014.

Is this grant opportunity still active?

No. It is archived and no longer active (archive date: June 7, 2014).

What kinds of activities was this FOA not intended to fund?

This FOA was not designed to pay for or scale up routine service delivery efforts already outlined in World Health Organization (WHO) obstetric fistula program materials. While it recognizes that affordability, transportation, and access to obstetric services matter, it focused on research projects that complement (rather than directly expand) those delivery-system efforts.

If service delivery scale-up was not the focus, what was NIH looking for instead?

NIH was looking for research that complements ongoing programmatic work to improve the timeliness and quality of care during labor, delivery, and the postpartum period, alongside clinical, social, and behavioral interventions that can prevent injuries, improve treatment success, and reduce long-term harm to women and children.

What broader strategy for eliminating obstetric fistula does the announcement reflect?

The announcement reflects the idea that eliminating fistula requires multiple approaches at once, including stronger emergency obstetric care and improved clinical, social, and behavioral interventions that address prevention, treatment outcomes, and long-term impacts.

What is the CFDA number associated with this opportunity?

The opportunity is associated with CFDA number 93.865, listed as Child Health and Human Development Extramural Research.

What activity category is listed for this grant?

The activity category is Health, Income Security and Social Services.

Who was eligible to apply?

Eligibility was broad. Eligible applicants included public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations); for-profit organizations (including small businesses); and various levels of government (state, county, city or township, and special districts), as well as public housing authorities and independent school districts.

Were historically underrepresented or mission-specific institutions explicitly included?

Yes. The FOA explicitly welcomed entities such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

Could non-U.S. organizations apply?

Yes. The FOA allowed non-U.S. entities (foreign organizations), regional organizations, U.S. territories or possessions, and eligible federal agencies.

Does the announcement indicate an intent to support research partnerships in high-prevalence settings?

Yes. By allowing foreign organizations, regional organizations, and U.S. territories/possessions, the eligibility language signals an intent to enable research partnerships and studies in settings where obstetric fistula is most prevalent.

Where could applicants find the full announcement?

The full archived announcement was made available through the NIH grants portal under PA-11-143.

Who was listed as a contact for access or technical linking issues?

NIH provided an Office of Extramural Research (OER) webmaster contact for access or technical linking issues related to the archived announcement.

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