Opportunity Information: Apply for NNH16ZTT001N GL
Apply for NNH16ZTT001N GL
- The NASA in the science and technology and other research and development sector is offering a public funding opportunity titled "Research Opportunities in Space Biology (ROSBio) – 2016 “GeneLab Innovation Awards for Translational Systems Biology and Informatics Research Using the GeneLab Data System” NASA Research Announcement (NRA): Appendix A" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 43.003.
- This funding opportunity was created on Mar 24, 2016 and posted on Mar 24, 2016.
- Applicants must submit their applications by Jun 28, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
NASA's Research Opportunities in Space Biology (ROSBio) 2016, Appendix A, titled "GeneLab Innovation Awards for Translational Systems Biology and Informatics Research Using the GeneLab Data System," is a competitive grant opportunity focused on getting more scientific value out of spaceflight biology data by using NASA's GeneLab Data System. The central purpose is translational: turning existing spaceflight-derived omics datasets into new, testable biological knowledge about how living systems respond to the space environment. Proposals are expected to use GeneLab as a required foundation, either by itself or alongside other publicly available spaceflight and ground-based omics databases, with an emphasis on open science utility and broad community benefit.
The solicitation is organized around two main research emphases. The first track, Systems Biology Informatics Research Using the GeneLab Data System, is aimed at tool-building and computational innovation. NASA is looking for proposals that create new computational biology methods, pipelines, software, or analytic approaches that enable novel informatics research and make GeneLab more usable and more valuable for future investigators. In practical terms, this means work that improves how researchers can discover, integrate, analyze, visualize, or interpret GeneLab datasets, potentially including capabilities that support reproducibility, interoperability with other resources, or more advanced systems-level analysis of multi-omics space biology data.
The second track, Systems Biology Experimental Research Using the GeneLab Data System, supports ground-based, hypothesis-driven experimental studies that start with insights derived from GeneLab analyses. The expectation is that investigators will mine GeneLab spaceflight data to generate concrete hypotheses, then test those hypotheses experimentally on the ground. These projects must clearly translate patterns found in spaceflight datasets into new biological understanding aligned with NASA life sciences mission needs. A key requirement is that the work should also contribute back to GeneLab by producing new data and information that can be added to the system, strengthening the resource for the larger research community and reinforcing the cycle of data reuse and knowledge building.
In terms of funding and project scope, NASA anticipated making up to three awards under this appendix. Each award was expected to run for roughly one to two years, with a total cost up to $250,000 per award (the listed award ceiling). The opportunity is issued as part of an omnibus NASA Research Announcement, and is characterized as a broad agency announcement under FAR 6.102(d)(2). Awards resulting from selections are expected to be issued as grants or cooperative agreements rather than procurement contracts.
Eligibility is broadly open across U.S. institutions, meaning essentially any category of U.S. organization may apply, subject to the stated terms in the full solicitation. Principal Investigators are allowed to collaborate widely, including with universities, federal laboratories, industry, and state or local government labs, and may also involve international collaborators, with the explicit exception of China. Submission is electronic and must be made by an authorized organizational official, not just an individual researcher, and the proposing organization must be registered in NASA's NSPIRES system with identified authorized representatives. Investigators and other participants (such as co-investigators) must also be registered, and applicants are advised to start registrations and system familiarization well ahead of deadlines to avoid last-minute submission problems.
Key dates and submission logistics are clearly defined. Appendix A was released around March 24, 2016, and could be located through the NSPIRES NASA Research Opportunities page under open solicitations. A non-binding Notice of Intent was due April 25, 2016 at 5:00 PM Eastern Time, and full proposals were due June 28, 2016 at 5:00 PM Eastern Time. The technical proposal section was limited to 15 pages. Applicants could submit through either NSPIRES or Grants.gov, but in all cases the submission had to follow the rules and structure described in the broader ROSBio-2016 omnibus NRA.
NASA noted that project selection would be informed by the National Research Council's 2011 Decadal Survey, "Recapturing a Future for Space Exploration: Life and Physical Sciences Research for a New Era," signaling that proposals should align with the larger strategic direction for space life sciences and the long-term needs of exploration. Programmatic questions were directed to Dr. David L. Tomko, Program Scientist for Space Biology at NASA Headquarters, while contracting and award administration questions were directed to Benjamin S. Benvenutti at the NASA Shared Services Center.
Frequently Asked Questions (FAQs)
1) What is this NASA funding opportunity?
This opportunity is NASA's Research Opportunities in Space Biology (ROSBio) 2016, Appendix A, titled "GeneLab Innovation Awards for Translational Systems Biology and Informatics Research Using the GeneLab Data System." It is a competitive grant opportunity focused on increasing scientific value from spaceflight biology data by using NASA's GeneLab Data System.
2) What is the main purpose of the GeneLab Innovation Awards?
The central purpose is translational: turning existing spaceflight-derived omics datasets into new, testable biological knowledge about how living systems respond to the space environment. Proposals are expected to deliver open-science utility and broad community benefit.
3) Is use of NASA GeneLab required?
Yes. Proposals are expected to use the GeneLab Data System as a required foundation, either alone or alongside other publicly available spaceflight and ground-based omics databases.
4) Can proposals use other databases in addition to GeneLab?
Yes. Proposals may use GeneLab by itself or in combination with other publicly available spaceflight and ground-based omics databases.
5) What are the two main research tracks (emphases) in this appendix?
The solicitation is organized around two main research emphases: (1) Systems Biology Informatics Research Using the GeneLab Data System, and (2) Systems Biology Experimental Research Using the GeneLab Data System.
6) What fits under the Systems Biology Informatics Research track?
This track is aimed at tool-building and computational innovation. NASA is looking for proposals that create new computational biology methods, pipelines, software, or analytic approaches that enable novel informatics research and make GeneLab more usable and more valuable for future investigators. Examples described include improvements to discovering, integrating, analyzing, visualizing, or interpreting GeneLab datasets, and potentially capabilities supporting reproducibility, interoperability, or advanced systems-level analysis of multi-omics space biology data.
7) What fits under the Systems Biology Experimental Research track?
This track supports ground-based, hypothesis-driven experimental studies that start with insights derived from GeneLab analyses. Investigators are expected to mine GeneLab spaceflight data to generate concrete hypotheses, then test those hypotheses experimentally on the ground, translating spaceflight-derived patterns into new biological understanding aligned with NASA life sciences mission needs.
8) Do experimental projects have to contribute back to GeneLab?
Yes. A key requirement stated for the experimental track is that the work should contribute back to GeneLab by producing new data and information that can be added to the system, strengthening the resource for the broader research community.
9) How many awards did NASA anticipate making?
NASA anticipated making up to three awards under this appendix.
10) What is the expected project period?
Each award was expected to run for roughly one to two years.
11) What is the maximum funding per award?
The listed award ceiling is a total cost up to $250,000 per award.
12) What type of solicitation is this?
The opportunity is issued as part of an omnibus NASA Research Announcement (NRA) and is characterized as a broad agency announcement under FAR 6.102(d)(2).
13) What kind of award instrument will NASA use?
Awards resulting from selections are expected to be issued as grants or cooperative agreements rather than procurement contracts.
14) Who is eligible to apply?
Eligibility is broadly open across U.S. institutions, meaning essentially any category of U.S. organization may apply, subject to the stated terms in the full solicitation.
15) Are collaborations allowed, and who can be collaborators?
Yes. Principal Investigators may collaborate widely, including with universities, federal laboratories, industry, and state or local government labs.
16) Are international collaborators allowed?
International collaborators may be involved, with the explicit exception of China.
17) Can an individual researcher submit directly?
No. Submission must be made electronically by an authorized organizational official, not solely by an individual researcher.
18) What registrations are required to submit?
The proposing organization must be registered in NASA's NSPIRES system with identified authorized representatives. Investigators and other participants (such as co-investigators) must also be registered. Applicants are advised to start registrations and system familiarization well ahead of deadlines to avoid last-minute submission problems.
19) Where can applicants find this appendix and submit proposals?
Appendix A could be located through the NSPIRES NASA Research Opportunities page under open solicitations. Applicants could submit through either NSPIRES or Grants.gov, but the submission must follow the rules and structure described in the broader ROSBio-2016 omnibus NRA.
20) What are the key dates for this opportunity?
Appendix A was released around March 24, 2016. A non-binding Notice of Intent was due April 25, 2016 at 5:00 PM Eastern Time. Full proposals were due June 28, 2016 at 5:00 PM Eastern Time.
21) Is the Notice of Intent required?
A Notice of Intent is described as non-binding, with a due date of April 25, 2016 at 5:00 PM Eastern Time.
22) What is the technical proposal page limit?
The technical proposal section was limited to 15 pages.
23) What broader guidance governs proposal structure and rules?
Even though this is Appendix A, proposals must follow the rules and structure described in the broader ROSBio-2016 omnibus NASA Research Announcement.
24) What strategic guidance was NASA using to inform selections?
NASA noted that project selection would be informed by the National Research Council's 2011 Decadal Survey, "Recapturing a Future for Space Exploration: Life and Physical Sciences Research for a New Era," indicating proposals should align with the larger strategic direction for space life sciences and long-term exploration needs.
25) Who should applicants contact for programmatic questions?
Programmatic questions were directed to Dr. David L. Tomko, Program Scientist for Space Biology at NASA Headquarters.
26) Who should applicants contact for contracting or award administration questions?
Contracting and award administration questions were directed to Benjamin S. Benvenutti at the NASA Shared Services Center.
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