Opportunity Information: Apply for PA 10 156
Apply for PA 10 156
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research Opportunities on Spasmodic Dysphonia (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders.
- This funding opportunity was created on Mar 30, 2010 and posted on Mar 30, 2010.
- Applicants must submit their applications by May 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Small businesses Public and State controlled institutions of higher education Independent school districts Native American tribal governments (Federally recognized) City or township governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Others (see text field entitled Additional Information on Eligibility for clarification) County governments Special district governments Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The National Institute on Deafness and Other Communication Disorders (NIDCD), part of the National Institutes of Health (NIH), released this funding opportunity announcement (FOA) to support new research focused on spasmodic dysphonia (SD), a voice disorder marked by involuntary spasms of the laryngeal muscles that disrupt normal speech. The overall aim of the opportunity is to push the field forward by improving scientific understanding of SD at a mechanistic level, with the practical long-term goals of better prevention strategies and more effective treatments. The FOA emphasizes innovative and collaborative projects and encourages investigators to bring together different disciplines so that SD research can progress more quickly than it would through isolated efforts.
In terms of the science that NIH is looking for, the announcement explicitly welcomes basic, translational, and clinical studies. That includes work aimed at understanding pathogenesis (how SD develops and what initiates it) and pathophysiology (how SD functions in the body and nervous system once it is present). It also highlights accelerating research into promising therapeutic approaches, meaning applicants can propose studies that move toward interventions, such as testing or refining treatment concepts, developing new tools to measure disease features, identifying biomarkers, clarifying patient subtypes, or studying mechanisms that could be targeted by future therapies. A central theme is transdisciplinary interaction, so applications that connect, for example, neuroscience, otolaryngology, speech-language pathology, neurology, genetics, bioengineering, imaging, computational methods, or other relevant areas are aligned with the intent of the program.
This particular FOA uses the R21 Research Project Grant mechanism (Funding Opportunity Number PA-10-156). In NIH terms, R21 awards are generally used to support exploratory, early-stage, or high-impact ideas that may be too preliminary for a larger definitive project. The announcement notes that it runs in parallel with a separate FOA of identical scientific scope that uses the R01 mechanism (PA-10-157), which is typically used for larger, more mature research projects. In other words, investigators could choose the mechanism that best matches the maturity and scale of their proposed SD research, with this FOA specifically targeting the R21 route.
Financially, the opportunity lists an award ceiling of $200,000, and it states there are no set-aside funds. That means NIH did not reserve a dedicated pot of money solely for this program; instead, how much is awarded and how many projects are funded depend on the number of applications submitted, their scientific quality, the proposed duration, and the budgets requested. Cost sharing or matching is not required, which reduces barriers for many applicants and is typical for NIH research grants.
Eligibility is broad and includes many organization types. Eligible applicants include public and private institutions of higher education, nonprofits with and without 501(c)(3) status, small businesses, and for-profit organizations (including those other than small businesses). Government entities are also included, such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing or Indian housing authorities. The FOA also explicitly includes tribal governments and tribal organizations, including federally recognized tribes and other tribal entities, as well as tribally controlled colleges and universities (TCCUs). In addition, the eligibility language includes U.S. territories or possessions, regional organizations, and non-U.S. entities (foreign organizations), along with various mission-focused institutional categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations. Federal agencies are listed as eligible as well, which can matter for intramural or interagency collaborative efforts depending on the project structure and NIH policy.
From an administrative standpoint, this is a discretionary grant in the health funding category under CFDA 93.173 (Research Related to Deafness and Communication Disorders). It was posted and created on March 30, 2010, with an original and final closing date of May 7, 2013, and it was archived on June 7, 2013. The full announcement was available through the NIH grants guide at the link provided in the source material. For access or technical issues, the FOA directs applicants to contact the NIH Office of Extramural Research (OER) webmaster via the provided email address.
Taken together, the opportunity was designed to seed and advance creative, cross-cutting SD research that clarifies underlying mechanisms and builds momentum toward improved diagnosis, prevention, and treatment, using the R21 mechanism to encourage exploratory and innovative projects that can open new directions for the field.
Frequently Asked Questions (FAQs)
What is this funding opportunity about?
This NIH funding opportunity announcement (FOA) from the National Institute on Deafness and Other Communication Disorders (NIDCD) supports new research on spasmodic dysphonia (SD), a voice disorder involving involuntary spasms of the laryngeal muscles that disrupt normal speech. The goal is to improve scientific understanding of SD mechanisms and, over the long term, enable better prevention strategies and more effective treatments.
Which NIH Institute is offering this FOA?
The FOA is offered by the National Institute on Deafness and Other Communication Disorders (NIDCD), which is part of the National Institutes of Health (NIH).
What research areas and study types are encouraged?
The FOA explicitly welcomes basic, translational, and clinical studies related to spasmodic dysphonia. This includes work that improves mechanistic understanding and supports progress toward prevention and treatment.
Does the FOA focus on how SD starts and how it works in the body?
Yes. The FOA highlights interest in studies of pathogenesis (how SD develops and what initiates it) and pathophysiology (how SD functions in the body and nervous system once it is present).
Are therapeutic or treatment-oriented projects allowed?
Yes. The FOA emphasizes accelerating research into promising therapeutic approaches. Applicants may propose studies that move toward interventions, such as testing or refining treatment concepts, identifying mechanisms that could be targeted by future therapies, or developing supporting tools and measurements.
What examples of proposed work does the FOA suggest?
The FOA notes that relevant projects may include developing new tools to measure disease features, identifying biomarkers, clarifying patient subtypes, and studying mechanisms that could be targeted by future therapies, alongside other basic, translational, or clinical approaches aligned with SD.
What is the central theme or emphasis of the program?
A central theme is innovation and transdisciplinary, collaborative interaction. The FOA encourages investigators to bring together different disciplines so SD research can progress more quickly than through isolated efforts.
What kinds of disciplines does NIH expect to see working together?
The FOA indicates that applications connecting multiple fields are aligned with program intent, including areas such as neuroscience, otolaryngology, speech-language pathology, neurology, genetics, bioengineering, imaging, computational methods, and other relevant disciplines.
What grant mechanism does this FOA use?
This FOA uses the NIH R21 Research Project Grant mechanism (Funding Opportunity Number PA-10-156).
What is an R21 intended to support in NIH terms?
R21 awards are generally used to support exploratory, early-stage, or high-impact ideas that may be too preliminary for a larger definitive project.
Is there a related FOA using a different NIH mechanism?
Yes. The announcement states it runs in parallel with a separate FOA of identical scientific scope that uses the R01 mechanism (PA-10-157), which is typically used for larger, more mature research projects.
How should an applicant choose between the R21 and the parallel R01?
Based on the FOA description, investigators could choose the mechanism that best matches the maturity and scale of their proposed SD research, with this FOA specifically targeting the R21 route for exploratory and innovative projects.
What is the maximum award amount listed for this opportunity?
The FOA lists an award ceiling of $200,000.
Are there set-aside funds reserved specifically for this program?
No. The FOA states there are no set-aside funds, meaning NIH did not reserve a dedicated pot of money solely for this program.
What factors influence how many projects may be funded and at what levels?
According to the FOA, funding levels and the number of awards depend on factors such as the number of applications submitted, their scientific quality, the proposed duration, and the budgets requested.
Is cost sharing or matching required?
No. The FOA states that cost sharing or matching is not required.
What types of organizations are eligible to apply?
Eligibility is broad and includes many organization types, such as public and private institutions of higher education; nonprofits with and without 501(c)(3) status; small businesses; and for-profit organizations (including those other than small businesses).
Are government entities eligible applicants?
Yes. The FOA includes government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing or Indian housing authorities.
Are tribal governments and tribal organizations eligible?
Yes. The FOA explicitly includes tribal governments and tribal organizations, including federally recognized tribes and other tribal entities, as well as tribally controlled colleges and universities (TCCUs).
Are U.S. territories or possessions included in eligibility?
Yes. The eligibility language includes U.S. territories or possessions.
Are non-U.S. (foreign) organizations eligible?
Yes. The FOA includes non-U.S. entities (foreign organizations) among eligible applicants.
Do mission-focused institution types qualify (for example HBCUs or Hispanic-serving institutions)?
Yes. The eligibility language includes categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations.
Are federal agencies eligible to apply?
Yes. Federal agencies are listed as eligible as well.
What is the funding category and assistance type?
The FOA is described as a discretionary grant in the health funding category.
What CFDA number is associated with this opportunity?
The opportunity is listed under CFDA 93.173 (Research Related to Deafness and Communication Disorders).
When was the FOA posted, and when did it close?
The FOA was posted and created on March 30, 2010. It lists an original and final closing date of May 7, 2013.
Is this funding opportunity still active?
No. The FOA was archived on June 7, 2013, and the final closing date shown is May 7, 2013.
Where was the full announcement made available?
The FOA indicates the full announcement was available through the NIH grants guide at the link provided in the source material.
Who should be contacted for access or technical issues related to the FOA?
For access or technical issues, the FOA directs applicants to contact the NIH Office of Extramural Research (OER) webmaster via the email address provided in the announcement.
What is the overall long-term impact the FOA is aiming for?
The FOA is intended to advance creative, cross-cutting SD research that clarifies underlying mechanisms and builds momentum toward improved diagnosis, prevention, and treatment, with a strong emphasis on innovative, collaborative projects.
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