Opportunity Information: Apply for PA 07 070

  • The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "Research Project Grant (Parent R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.143 NIEHS Superfund Hazardous SubstancesBasic Research and Education 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.361 Nursing Research 93.389 National Center for Research Resources 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance.
  • This funding opportunity was created on Dec 5, 2008 and posted on Nov 20, 2006.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public and State controlled institutions of higher education For profit organizations other than small businesses Private institutions of higher education Public housing authorities/Indian housing authorities State governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments County governments.
  • Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
Apply for PA 07 070

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Opportunity Summary:

The Research Project Grant (Parent R01), Funding Opportunity Number PA 07 070, is a National Institutes of Health (NIH) grant program designed to support a single, well-defined research project led by one or more named investigators at an applicant institution or organization. The core idea of the R01 mechanism is to fund a discrete, specific, and clearly scoped project that reflects the expertise and research direction of the investigator(s), rather than funding broad institutional capacity or loosely defined activities. To be competitive and eligible for assignment within NIH, the proposed research plan must align with the mission and program interests of at least one participating NIH Institute or Center (IC). Applications submitted under this parent announcement are routed and assigned using standard Public Health Service referral rules, with final assignment driven by both scientific fit and the stated interests of the ICs. Applicants are encouraged to review NIH IC program descriptions and consult IC materials to ensure a strong match before submitting.

This opportunity uses the NIH R01 award mechanism, which is NIH's flagship research project grant format and is widely used across biomedical, behavioral, clinical, and health services research. Because R01 projects can vary dramatically in scale, approach, and scientific area, NIH does not set a single uniform award size or a fixed number of awards for this announcement. Instead, both the budget level and project duration are expected to vary by application, and the overall number of awards and total dollars ultimately depend on how many applications are submitted, how strong they are in peer review, and the requested costs and timeframes of the projects selected for funding.

The funding activity categories tied to this announcement span a wide range of public interest areas, including education, environment, food and nutrition, health, income security, and social services, reflecting the breadth of NIH-supported research when mapped across federal catalog categories. The listed CFDA programs show just how broad the scientific scope can be under this parent R01, covering fields such as environmental health, oral health, hazardous substances and Superfund-related research, human genomics, deafness and communication disorders, complementary and integrative health, sleep disorders, mental health, alcohol and drug use and addiction, technological innovations for human health, nursing research, cancer research across prevention through treatment and control, cardiovascular and pulmonary disease, blood disorders, arthritis and musculoskeletal conditions, diabetes and kidney/digestive diseases, neuroscience and neurological disorders, allergy/immunology/transplantation, infectious diseases and microbiology, child health and development, aging, vision research, and medical library assistance. In practice, this means the parent R01 is not limited to a narrow topic area; it is a general funding pathway for investigator-initiated research that must fit within at least one NIH IC's scientific mission.

Eligibility is broad and includes many types of applicant organizations. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (other than small businesses, though small businesses are also listed as eligible), independent school districts, state and local governments (including city/township and county governments), special district governments, public housing authorities and Indian housing authorities, and Native American tribal governments and tribal organizations. The announcement also explicitly states that foreign institutions are eligible to apply, eligible federal agencies may apply, and faith-based or community-based organizations may apply, which is important for applicants outside traditional academic medical centers. There is no cost-sharing or matching requirement, so applicants are not required to provide institutional matching funds as a condition of eligibility.

Timing is handled through multiple receipt dates rather than a single deadline, meaning applicants can submit on recurring standard NIH due dates specified in the full announcement. The opportunity was posted on November 20, 2006, has multiple receipt dates for submissions, and the archived date listed is February 2, 2010, indicating the specific listing is historical even though the parent R01 concept and NIH R01 submissions continue under updated announcements. For full details and the authoritative requirements, the opportunity points applicants to the NIH grants guide page for PA 07 070. For technical issues accessing or linking to the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

In practical terms, this parent R01 opportunity is best understood as NIH's general entry point for investigator-driven projects: applicants propose a focused research plan, demonstrate alignment with an NIH Institute or Center, and compete through NIH's standard referral and review process. The flexibility in topic area, institutional eligibility, and project scale is balanced by the expectation that the work is clearly defined, scientifically rigorous, and a strong fit for NIH program priorities.

FAQs: NIH Research Project Grant (Parent R01) - PA 07 070

What is the Research Project Grant (Parent R01) under PA 07 070?

PA 07 070 is an NIH funding opportunity that uses the R01 award mechanism to support a single, well-defined research project led by one or more named investigators at an applicant institution or organization. The intent is to fund a discrete, specific, clearly scoped project that reflects the expertise and research direction of the investigator(s).

What is the main purpose of an NIH R01 in this announcement?

The core purpose is to fund a focused research plan rather than broad institutional capacity building or loosely defined activities. The project should be clearly defined and scientifically rigorous.

Is this opportunity limited to a specific research topic area?

No. This parent R01 is described as a general funding pathway for investigator-initiated research. The topic can be broad, as long as the proposed research aligns with the mission and program interests of at least one participating NIH Institute or Center (IC).

Does my application need to align with an NIH Institute or Center (IC)?

Yes. To be eligible for assignment within NIH and to be competitive, the research plan must align with the mission and program interests of at least one participating NIH Institute or Center.

How are applications routed and assigned within NIH?

Applications submitted under this parent announcement are routed and assigned using standard Public Health Service referral rules. Final assignment is driven by scientific fit and the stated interests of the NIH Institutes and Centers.

Should applicants review NIH Institute/Center program interests before applying?

Yes. Applicants are encouraged to review NIH IC program descriptions and consult IC materials to ensure a strong match between the proposed project and IC interests before submitting.

What award mechanism does this opportunity use?

This opportunity uses the NIH R01 mechanism, NIH's flagship research project grant format used widely across biomedical, behavioral, clinical, and health services research.

Is there a standard award amount for PA 07 070?

No. NIH does not set a single uniform award size for this parent R01 announcement. Award sizes can vary substantially depending on the proposed project.

Is there a standard project period (duration) for awards under this announcement?

No. Project duration is expected to vary by application, reflecting differences in scope and approach across proposed projects.

Does NIH specify the number of awards that will be made?

No. The number of awards and total dollars depend on factors such as the number of applications received, their scientific strength in peer review, and the requested costs and timeframes of projects selected for funding.

What kinds of funding activity categories are associated with this announcement?

The funding activity categories span multiple public interest areas, including education, environment, food and nutrition, health, income security, and social services, reflecting the breadth of NIH-supported research when mapped across federal catalog categories.

What scientific areas can fit under this parent R01?

The listed CFDA programs illustrate broad scope, including areas such as environmental health, oral health, hazardous substances and Superfund-related research, human genomics, deafness and communication disorders, complementary and integrative health, sleep disorders, mental health, alcohol and drug use and addiction, technological innovations for human health, nursing research, cancer (prevention through treatment and control), cardiovascular and pulmonary disease, blood disorders, arthritis and musculoskeletal conditions, diabetes and kidney/digestive diseases, neuroscience and neurological disorders, allergy/immunology/transplantation, infectious diseases and microbiology, child health and development, aging, vision research, and medical library assistance.

Who is eligible to apply?

Eligibility is broad. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (other than small businesses, though small businesses are also listed as eligible), independent school districts, state and local governments (including city/township and county governments), special district governments, public housing authorities and Indian housing authorities, and Native American tribal governments and tribal organizations.

Are foreign institutions eligible to apply?

Yes. The announcement explicitly states that foreign institutions are eligible to apply.

Can federal agencies apply?

Yes. The announcement states that eligible federal agencies may apply.

Are faith-based or community-based organizations eligible?

Yes. The announcement explicitly states that faith-based or community-based organizations may apply.

Is cost sharing or matching required?

No. There is no cost-sharing or matching requirement for this opportunity.

Is there a single deadline to apply?

No. Timing is handled through multiple receipt dates rather than a single deadline. Applicants can submit on recurring standard NIH due dates specified in the full announcement.

When was this opportunity posted and when was it archived?

The opportunity was posted on November 20, 2006. The archived date listed is February 2, 2010, indicating this specific listing is historical.

Where can applicants find the authoritative requirements and full details?

The opportunity directs applicants to the NIH grants guide page for PA 07 070 for full details and authoritative requirements.

Who should be contacted for technical issues accessing or linking to the announcement?

For technical issues accessing or linking to the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

What is the practical way to think about the parent R01 opportunity?

It functions as NIH's general entry point for investigator-driven projects: propose a focused research plan, demonstrate alignment with an NIH Institute or Center, and compete through NIH's standard referral and review process. The opportunity is flexible in topic area, institutional eligibility, and project scale, but expects the work to be clearly defined and a strong fit for NIH program priorities.

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