Opportunity Information: Apply for RFA OD 12 002

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research Resource for Human Organs and Tissues (U42)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351 Research Infrastructure Programs.
  • This funding opportunity was created on Jun 13, 2012 and posted on Jun 13, 2012.
  • Applicants must submit their applications by Oct 23, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Small businesses Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts State governments Native American tribal organizations (other than Federally recognized tribal governments) County governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments For profit organizations other than small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The NIH funding opportunity RFA-OD-12-002, titled "Research Resource for Human Organs and Tissues (U42)," is a discretionary grant announcement that uses the cooperative agreement mechanism (U42). Its central goal is to maintain and strengthen a national research resource that makes human organs and tissues reliably available to biomedical researchers across the United States. This program is positioned as a continuation of an earlier effort previously supported under RFA-RR-07-006, and it focuses on sustaining the infrastructure and coordinated operations needed to obtain, preserve, and distribute human biological materials for research use.

At a practical level, the resource supported under this FOA is expected to function as a service-oriented hub for the research community. The emphasis is not on funding a single laboratory research project, but on supporting the operational capabilities that enable many downstream studies by other investigators. That includes facilitating procurement of human organs and tissues, implementing appropriate preservation methods to maintain sample integrity, and managing the distribution of these materials to qualified biomedical researchers. In other words, the award is meant to underwrite the logistics, systems, and expertise required to move scarce, high-value human specimens from sources to researchers in a way that is timely, consistent, and usable for a wide range of scientific needs.

Because the funding instrument is a cooperative agreement, the relationship between NIH and the awardee is expected to be more collaborative than in a standard grant. Cooperative agreements typically involve substantial programmatic involvement from the funding agency, which often means NIH may participate in oversight, coordination, or steering decisions to ensure the resource meets national research needs, operates effectively, and remains aligned with the program goals described in the FOA. The end result NIH is seeking is a stable, well-managed national capability that improves researchers access to human organs and tissues, rather than ad hoc or fragmented access dependent on local availability.

This opportunity was posted on June 13, 2012, with an original and current application closing date of October 23, 2012, and an archive date of November 23, 2012. The FOA projected a single award (ExpectedAwards: 1) with an estimated total funding level of $1,500,000. No cost sharing or matching was required, which generally reduces barriers for applicants by allowing the project to be supported without mandatory institutional financial contribution beyond typical grant-supported infrastructure and compliance costs.

Eligibility for this FOA was broad across the U.S. research ecosystem. Eligible applicants included small businesses, for-profit organizations (other than small businesses), nonprofit organizations with or without 501(c)(3) status (excluding where otherwise limited), and a wide range of government entities such as state governments, county governments, city or township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities. Institutions of higher education were eligible in both private and public/state-controlled forms. The announcement also explicitly noted additional eligible applicant categories, including Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), tribally controlled colleges and universities (TCCUs), regional organizations, U.S. territories or possessions, and Indian/Native American tribal organizations and governments, including those other than federally recognized tribal governments.

At the same time, the FOA clearly restricted foreign participation. Non-U.S. entities (foreign institutions) were not eligible to apply, and non-U.S. components of U.S. organizations were also not eligible. In addition, foreign components as defined by the NIH Grants Policy Statement were not allowed. These limits indicate NIH intended the supported resource to be based and operated domestically, serving U.S. biomedical researchers and aligning with U.S. regulatory and programmatic expectations.

The awarding agency is the National Institutes of Health, and the activity aligns with the health-related research infrastructure domain (CFDA 93.351, Research Infrastructure Programs). For applicants or readers seeking the full announcement details, NIH provided an additional information link to the full FOA on the NIH grants website. NIH also listed the NIH Office of Extramural Research (OER) webmaster contacts for technical difficulties accessing or linking to the announcement, reflecting that administrative questions about the electronic posting were handled through OER support channels.

Frequently Asked Questions (FAQs): NIH RFA-OD-12-002 "Research Resource for Human Organs and Tissues (U42)"

What is the funding opportunity called and what is its FOA number?

The funding opportunity is titled "Research Resource for Human Organs and Tissues (U42)" and its NIH FOA number is RFA-OD-12-002.

Which agency is offering this opportunity?

This opportunity is offered by the National Institutes of Health (NIH).

What mechanism will NIH use to make the award?

The award uses the cooperative agreement mechanism, specifically a U42.

What does it mean that this is a cooperative agreement (U42)?

A cooperative agreement indicates a more collaborative relationship with NIH than a standard grant. NIH is expected to have substantial programmatic involvement, which may include participation in oversight, coordination, or steering decisions to help ensure the resource meets national research needs and aligns with the FOA goals.

What is the main purpose of this FOA?

The central purpose is to maintain and strengthen a national research resource that makes human organs and tissues reliably available to biomedical researchers across the United States.

Is this opportunity intended to fund a single research project or a shared resource?

It is intended to support a service-oriented national resource, not a single laboratory research project. The emphasis is on sustaining infrastructure and coordinated operations that enable many downstream studies by other investigators.

What kinds of activities is the resource expected to perform?

Based on the FOA description provided, the supported resource is expected to facilitate procurement of human organs and tissues, implement appropriate preservation methods to maintain sample integrity, and manage distribution of these materials to qualified biomedical researchers.

What is the intended outcome NIH is seeking?

NIH is seeking a stable, well-managed national capability that improves researchers' access to human organs and tissues, rather than ad hoc or fragmented access that depends on local availability.

Is this FOA related to a previous NIH effort?

Yes. This FOA is positioned as a continuation of an earlier effort previously supported under RFA-RR-07-006.

How many awards did NIH expect to make under this FOA?

The FOA projected a single award (ExpectedAwards: 1).

What is the estimated total funding level for this opportunity?

The estimated total funding level listed for this FOA is $1,500,000.

Is cost sharing or matching required?

No. The FOA states that no cost sharing or matching is required.

When was this opportunity posted?

The FOA was posted on June 13, 2012.

What was the application closing date?

The original and current application closing date was October 23, 2012.

When was the FOA archived?

The archive date was November 23, 2012.

What is the CFDA number and program area associated with this opportunity?

The activity aligns with CFDA 93.351, Research Infrastructure Programs.

What types of organizations were eligible to apply?

Eligibility was broad and included small businesses; for-profit organizations (other than small businesses); nonprofit organizations with or without 501(c)(3) status; and a wide range of government entities (including state, county, city or township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities). Institutions of higher education were eligible in both private and public/state-controlled forms.

Were any additional applicant categories explicitly listed as eligible?

Yes. The FOA explicitly noted eligibility for Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), tribally controlled colleges and universities (TCCUs), regional organizations, U.S. territories or possessions, and Indian/Native American tribal organizations and governments (including those other than federally recognized tribal governments).

Are foreign institutions eligible to apply?

No. Non-U.S. entities (foreign institutions) were not eligible to apply.

Can a non-U.S. component of a U.S. organization participate as part of the application?

No. Non-U.S. components of U.S. organizations were not eligible.

Are foreign components (as defined by the NIH Grants Policy Statement) allowed?

No. The FOA states that foreign components, as defined by the NIH Grants Policy Statement, were not allowed.

Who is the resource intended to serve?

The resource is intended to serve biomedical researchers across the United States by providing reliable access to human organs and tissues for research use.

Where can applicants find the full announcement?

NIH provided an additional information link to the full FOA on the NIH grants website.

Who should be contacted for technical difficulties accessing the announcement online?

The FOA listed NIH Office of Extramural Research (OER) webmaster contacts for technical difficulties accessing or linking to the announcement.

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