Opportunity Information: Apply for RFA AT 12 001
Apply for RFA AT 12 001
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research Resource for Systematic Reviews of Complementary and Alternative Medicine Clinical Trials (R24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213 Research and Training in Complementary and Integrative Health.
- This funding opportunity was created on Aug 9, 2011 and posted on Aug 9, 2011.
- Applicants must submit their applications by Nov 15, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $600,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- Eligible applicants include: For profit organizations other than small businesses Public housing authorities/Indian housing authorities Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Native American tribal governments (Federally recognized) Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public and State controlled institutions of higher education Small businesses County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The National Center for Complementary and Alternative Medicine (NCCAM), within the National Institutes of Health, released this R24 grant opportunity to build and sustain a research resource that makes it easier to carry out rigorous systematic reviews of complementary and alternative medicine (CAM) clinical trials. The central deliverable is a curated database made up of primary reports from controlled clinical trials across the full range of CAM interventions. By organizing and maintaining these trial reports in a structured, searchable way, the project is meant to reduce the time and effort required to find relevant studies, assess the evidence fairly, and summarize results in a way that supports evidence-based decisions in clinical care, patient decision-making, health policy, and research planning.
A key part of the program is that the database is not intended to sit on a shelf. The funded team is expected to actively use the resource to produce high-quality systematic reviews and, when appropriate, meta-analyses of published CAM trial evidence. The FOA makes clear that systematic reviews should be comprehensive and unbiased, meaning they should attempt to identify all relevant controlled trials on a topic, evaluate their quality, and synthesize findings in a transparent manner. Applications must include a commitment to complete at least two to three systematic reviews per year, with meta-analysis included when the available data support meaningful quantitative pooling. Proposals that do not include both the database resource component and this minimum annual systematic review output are considered non-responsive, which is essentially a disqualifying issue.
Beyond building the resource and producing reviews, the FOA emphasizes service to the broader scientific community. Applicants must explain how they will ensure access and availability of the database for other researchers, and they must also provide editorial, methodological, and technical support to outside users who want to conduct systematic reviews using the resource. In practice, this implies planning for things like user access policies, documentation and training materials, standardized data elements, quality control procedures, and responsive technical assistance so that the resource can be widely used and consistently interpreted.
This was a discretionary NIH grant opportunity categorized under health (CFDA 93.213, Research and Training in Complementary and Integrative Health). The Funding Opportunity Number is RFA-AT-12-001, posted August 9, 2011, with an original and current closing date of November 15, 2011, and an archive date of December 16, 2011. The estimated total funding amount is $600,000, with an award ceiling of $600,000, and there is no cost sharing or matching requirement stated.
Eligibility is broad and includes many organization types, such as public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations other than small businesses, small businesses, state and local governments, tribal governments and tribal organizations, public housing authorities, and other categories noted in the announcement. Additional eligible applicants called out include U.S. territories or possessions, foreign organizations (non-U.S. entities), regional organizations, faith-based or community-based organizations, and several types of minority-serving institutions (including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities). The full announcement and details were provided through the NIH grants posting associated with the FOA link in the notice.
Frequently Asked Questions (FAQs)
What is this grant opportunity?
This is an NIH NCCAM (National Center for Complementary and Alternative Medicine) R24 grant opportunity to build and sustain a research resource that supports rigorous systematic reviews of complementary and alternative medicine (CAM) clinical trials.
What is the main purpose of the project?
The project is intended to reduce the time and effort required to find relevant CAM controlled clinical trials, assess the evidence fairly, and summarize results in a transparent way that supports evidence-based decisions in clinical care, patient decision-making, health policy, and research planning.
What is the central deliverable required by the FOA?
The central deliverable is a curated, structured, searchable database made up of primary reports from controlled clinical trials across the full range of CAM interventions.
What kinds of studies are included in the database?
The database is composed of primary reports from controlled clinical trials covering the full range of complementary and alternative medicine interventions, as described in the opportunity.
Is the database meant to be a standalone resource, or must it be actively used?
The FOA emphasizes that the database is not intended to sit on a shelf. The funded team is expected to actively use the resource to produce high-quality systematic reviews and, when appropriate, meta-analyses of published CAM trial evidence.
How many systematic reviews are applicants required to produce each year?
Applications must include a commitment to complete at least two to three systematic reviews per year.
Are meta-analyses required?
Meta-analysis is expected when the available data support meaningful quantitative pooling. In other words, meta-analyses should be included when appropriate based on the evidence.
What does the FOA mean by a "comprehensive and unbiased" systematic review?
The FOA states that systematic reviews should attempt to identify all relevant controlled trials on a topic, evaluate their quality, and synthesize findings in a transparent manner.
What happens if an application proposes only the database or only systematic reviews?
Proposals that do not include both the database resource component and the minimum annual systematic review output (two to three reviews per year) are considered non-responsive, which the FOA treats as a disqualifying issue.
Who is expected to use the database besides the funded team?
The FOA emphasizes service to the broader scientific community. Applicants must explain how they will ensure access and availability of the database for other researchers.
What support must the funded team provide to outside researchers?
The funded team must provide editorial, methodological, and technical support to outside users who want to conduct systematic reviews using the resource.
What practical elements should applicants plan for to support outside users?
The opportunity implies planning for user access policies, documentation and training materials, standardized data elements, quality control procedures, and responsive technical assistance so the resource can be widely used and consistently interpreted.
Which agency and NIH center issued this funding opportunity?
The funding opportunity was released by the National Center for Complementary and Alternative Medicine (NCCAM) within the National Institutes of Health (NIH).
What is the Funding Opportunity Number?
The Funding Opportunity Number is RFA-AT-12-001.
What is the assistance listing / CFDA number and program category?
The opportunity is categorized under health and is associated with CFDA 93.213, Research and Training in Complementary and Integrative Health.
What type of NIH grant mechanism is this?
This opportunity uses the R24 mechanism and is described as a discretionary NIH grant opportunity.
When was the opportunity posted, and what were the closing dates?
The FOA was posted on August 9, 2011. The original closing date and the current closing date were both November 15, 2011.
When was the opportunity archived?
The archive date listed for the opportunity is December 16, 2011.
How much funding is available under this FOA?
The estimated total funding amount is $600,000.
What is the award ceiling?
The award ceiling is $600,000.
Is cost sharing or matching required?
No cost sharing or matching requirement is stated in the information provided.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) entities); for-profit organizations other than small businesses; small businesses; state and local governments; tribal governments and tribal organizations; public housing authorities; and other categories noted in the announcement.
Are foreign (non-U.S.) organizations eligible?
Yes. The opportunity explicitly lists foreign organizations (non-U.S. entities) among the eligible applicants, along with U.S. territories or possessions and regional organizations.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly listed among eligible applicant types.
Are minority-serving institutions specifically eligible?
Yes. The announcement calls out several types of minority-serving institutions, including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities.
Where were the full announcement and details provided?
The full announcement and details were provided through the NIH grants posting associated with the FOA link referenced in the notice.
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