Opportunity Information: Apply for RFA NR 12 011
Apply for RFA NR 12 011
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Research to Assist Informal Caregivers in Assessing and Managing Symptoms in Individuals with Alzheimers Disease (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361 Nursing Research.
- This funding opportunity was created on Mar 19, 2012 and posted on Mar 19, 2012.
- Applicants must submit their applications by May 21, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- Eligible applicants include: Special district governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses State governments Small businesses Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education City or township governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The grant opportunity titled "Research to Assist Informal Caregivers in Assessing and Managing Symptoms in Individuals with Alzheimers Disease (R01)" (Funding Opportunity Number RFA-NR-12-011) is a National Institutes of Health discretionary research grant designed to improve how unpaid, nonprofessional caregivers recognize and respond to challenging symptoms in people living with Alzheimers disease and related dementias. The central goal is practical: support research that results in better tools, techniques, and caregiver-focused interventions so families and other informal caregivers can more accurately assess adverse symptoms and manage them more effectively in everyday settings. In other words, this program is aimed at helping caregivers make better decisions in real time about symptoms that commonly arise in dementia, and at reducing the burden and negative outcomes that can occur when symptoms are missed, misunderstood, or poorly managed.
This opportunity uses the NIH R01 research project grant mechanism, which is typically intended for well-developed research projects that can produce generalizable findings. The funding announcement emphasizes two connected areas of work: first, developing or refining methods caregivers can use to assess symptoms in individuals with dementia; and second, developing and testing interventions that improve symptom management once problems are identified. While the announcement text provided here does not list specific symptom domains, the phrase "adverse symptoms" in Alzheimers and related dementias generally points to issues that complicate home care and safety, such as behavioral and psychological symptoms (for example agitation, aggression, anxiety, depression, sleep disruption, wandering), communication difficulties, pain recognition, medication side effects, functional decline, or other distressing or health-threatening changes. Projects under this grant would be expected to move beyond describing the problem and instead produce actionable caregiver-facing approaches, such as structured assessment tools, decision supports, training programs, or home-based strategies that can be used without requiring a clinician to be present.
From a funding and administrative standpoint, the announcement lists an estimated total funding amount of $2,500,000 for the program, with an award ceiling of $350,000. The posting date and creation date were March 19, 2012. The original and current closing date were both May 21, 2012, and the opportunity was later archived on June 21, 2012. The CFDA number associated with the opportunity is 93.361, categorized under Nursing Research, reflecting the Institute or programmatic home and the caregiving-focused nature of the research.
Eligibility is broad and includes many types of U.S.-based organizations. Eligible applicants include public and private institutions of higher education (including public/state-controlled and private universities), nonprofits with or without 501(c)(3) status (as long as they meet NIH eligibility requirements), for-profit organizations (including small businesses, though this is an R01 rather than an SBIR/STTR mechanism), and a range of government entities such as state, county, city or township governments, special district governments, independent school districts, and public housing authorities including Indian housing authorities. The eligibility section also highlights additional categories commonly called out in NIH announcements, including historically Black colleges and universities, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Importantly, foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible. The announcement also specifies that foreign components, as defined by NIH policy, are not allowed, which means the proposed work must be fully domestic in the NIH sense even if it involves internationally relevant questions.
Cost sharing or matching is not required, which is typical for NIH research grants and reduces barriers for organizations that may not have the ability to provide additional non-federal funds. As with most NIH FOAs, the expectation would be that applicants propose a rigorous research plan with clear aims, an appropriate study design, meaningful outcomes for caregivers and persons with dementia, and a pathway to dissemination or implementation. Because the focus is on informal caregivers, strong applications would usually be grounded in the realities of home and community care, including the time constraints, stress levels, health literacy differences, and cultural considerations that shape how caregivers notice symptoms and carry out management strategies. Research supported by this program would ideally translate into tools that are feasible, reliable, and acceptable to caregivers, and interventions that can demonstrate measurable improvements such as reduced symptom severity or frequency, fewer caregiver errors or crises, reduced caregiver burden, better quality of life, improved safety, or better coordination with clinical care.
For applicants seeking the original full announcement text, the funding notice points to the NIH grants page link (http://grants.nih.gov/grants/guide/rfa-files/RFA-NR-12-011.html). For technical issues accessing or linking to the announcement, the contact provided is the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the title of this grant opportunity?
The opportunity is titled "Research to Assist Informal Caregivers in Assessing and Managing Symptoms in Individuals with Alzheimers Disease (R01)."
What is the Funding Opportunity Number (FOA)?
The Funding Opportunity Number is RFA-NR-12-011.
Which agency is offering this grant?
This is a National Institutes of Health (NIH) discretionary research grant.
What is the main purpose of this funding opportunity?
The central goal is to support research that helps unpaid, nonprofessional (informal) caregivers better recognize, assess, and manage challenging or adverse symptoms in individuals living with Alzheimers disease and related dementias, especially in everyday home and community settings.
Who is the focus population for the research supported by this program?
The focus is on informal caregivers (unpaid, nonprofessional caregivers) who provide care to people with Alzheimers disease and related dementias.
What types of projects does this opportunity support?
The announcement emphasizes two connected areas of work: (1) developing or refining methods caregivers can use to assess symptoms in individuals with dementia, and (2) developing and testing interventions that improve symptom management once problems are identified.
What does "informal caregiver" mean in this opportunity?
Based on the description provided, informal caregivers are unpaid, nonprofessional caregivers (for example, family members or others providing day-to-day care outside of a formal clinical role).
What is meant by "assessing symptoms" in the context of this grant?
Assessing symptoms refers to helping caregivers more accurately recognize and evaluate adverse or challenging symptoms in people with dementia, using practical caregiver-facing approaches such as structured assessment tools or decision supports that can be used without a clinician present.
What is meant by "managing symptoms" in the context of this grant?
Managing symptoms refers to developing and testing practical interventions, techniques, training, or home-based strategies that help caregivers respond more effectively after symptoms are identified, with the goal of improving real-time decision-making and reducing negative outcomes.
What kinds of symptoms are addressed by this funding opportunity?
The provided text does not list specific symptom domains. It uses the phrase "adverse symptoms" in Alzheimers and related dementias and gives examples of symptom types that commonly complicate home care and safety, such as agitation, aggression, anxiety, depression, sleep disruption, wandering, communication difficulties, pain recognition challenges, medication side effects, functional decline, and other distressing or health-threatening changes.
Is this opportunity intended for basic research or practical caregiver tools and interventions?
The central goal described is practical: research is expected to move beyond describing the problem and instead produce actionable caregiver-facing approaches (for example, assessment tools, decision supports, training programs, or home-based strategies) that can be used in everyday settings.
What grant mechanism is used for this opportunity?
This opportunity uses the NIH R01 research project grant mechanism.
What does the R01 mechanism imply about the type of project expected?
The R01 mechanism is typically intended for well-developed research projects that can produce generalizable findings.
What is the estimated total funding amount for the program?
The estimated total funding amount listed is $2,500,000.
What is the award ceiling for this opportunity?
The award ceiling listed is $350,000.
Is cost sharing or matching required?
No. The announcement states that cost sharing or matching is not required.
What is the CFDA number associated with this grant?
The CFDA number is 93.361.
How is this opportunity categorized?
It is categorized under Nursing Research, reflecting the caregiving-focused nature of the research and the programmatic home indicated in the information provided.
When was this opportunity posted?
The posting date is March 19, 2012.
When was this opportunity created?
The creation date is March 19, 2012.
What was the application closing date?
The original closing date and the current closing date were both May 21, 2012.
Is this funding opportunity still open?
No. The opportunity was archived on June 21, 2012.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S.-based organizations, including public and private institutions of higher education, nonprofits with or without 501(c)(3) status (as long as they meet NIH eligibility requirements), for-profit organizations (including small businesses), and a range of government entities (state, county, city or township governments, special district governments, independent school districts, and public housing authorities including Indian housing authorities).
Are minority-serving institutions included in the eligible applicant types?
Yes. The eligibility section highlights categories commonly called out in NIH announcements, including historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, and Alaska Native and Native Hawaiian serving institutions.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly included in the eligible applicant categories listed.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are included among the eligible applicant categories listed.
Are federal agencies eligible to apply?
Yes. The eligibility list includes eligible federal agencies.
Can foreign institutions apply?
No. Foreign institutions are not eligible to apply.
Can a U.S. organization include a non-U.S. component in the proposed work?
No. The information provided specifies that non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
Does the restriction on foreign components affect where the work must be conducted?
Yes. The provided text indicates the proposed work must be fully domestic in the NIH sense, even if the research questions have international relevance.
What kinds of outputs or deliverables are encouraged by the announcement?
The description points to caregiver-facing outputs such as structured assessment tools, decision supports, training programs, or home-based strategies designed for use in real-world caregiving situations without requiring a clinician to be present.
What outcomes does the announcement suggest projects should be able to improve?
The information provided suggests measurable improvements such as reduced symptom severity or frequency, fewer caregiver errors or crises, reduced caregiver burden, better quality of life, improved safety, or better coordination with clinical care.
Does the opportunity describe expectations about the research approach?
Yes. The description indicates that, as with most NIH FOAs, applicants are expected to propose a rigorous research plan with clear aims, an appropriate study design, meaningful outcomes for caregivers and persons with dementia, and a pathway to dissemination or implementation.
Does the opportunity emphasize real-world feasibility for caregivers?
Yes. The information provided emphasizes grounding projects in the realities of home and community care, including caregiver time constraints, stress levels, differences in health literacy, and cultural considerations that shape how symptoms are noticed and management strategies are carried out.
Where can applicants find the original full announcement text?
The funding notice points to the NIH grants page link: http://grants.nih.gov/grants/guide/rfa-files/RFA-NR-12-011.html
Who should be contacted for technical issues accessing or linking to the announcement?
For technical issues, the contact provided is the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.
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