Opportunity Information: Apply for RFA HS 14 004

  • The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "Researcher Training and Workforce Development in Methods and Standards for Conducting Patient Centered Outcomes Research Studies (R25)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226 Research on Healthcare Costs, Quality and Outcomes.
  • This funding opportunity was created on Jul 10, 2013 and posted on Jul 10, 2013.
  • Applicants must submit their applications by Sep 27, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • Eligible applicants include: Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Eligible Agencies of the Federal Government Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply.
Apply for RFA HS 14 004

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Opportunity Summary:

The Agency for Healthcare Research and Quality (AHRQ) released this discretionary grant opportunity, titled "Researcher Training and Workforce Development in Methods and Standards for Conducting Patient Centered Outcomes Research Studies (R25)," under Funding Opportunity Number RFA-HS-14-004. The program is designed to strengthen the national research workforce by supporting the creation of structured education and training programs that teach researchers how to plan, conduct, analyze, and evaluate high-quality comparative clinical effectiveness research (CER) and patient-centered outcomes research (PCOR). At its core, the FOA aims to expand capacity across the United States so that more investigators and research teams can reliably apply accepted methodologies and methodological standards when generating evidence that compares health interventions, services, or approaches to care in real-world settings.

Funded projects are expected to develop, implement, and evaluate an education program specifically focused on CER/PCOR methods and standards. AHRQ is looking for programs that are deliberately designed around the needs of a particular professional field, work environment, or defined researcher community, meaning applicants should tailor the training to the realities of the intended audience rather than offering a generic curriculum. The emphasis is on innovative training models that are practical and relevant to the settings where CER/PCOR is performed, such as academic institutions, health systems, research networks, and other applied research environments.

A central requirement is that the education program must be multi-component and include a progression of training levels. Programs need to offer basic instruction for foundational knowledge, advanced instruction for deeper methodological competence, and experiential training that allows participants to apply methods in practice. The experiential element signals that AHRQ wants more than lectures or short courses; trainees should have opportunities such as mentored projects, hands-on workshops, applied analyses, protocol development exercises, or similar activities that build real competency and confidence using CER/PCOR approaches.

In terms of subject matter, the FOA allows broad coverage of research designs commonly used in CER/PCOR. Programs may focus on methods for designing and analyzing systematic reviews and technology assessments, as well as primary research approaches such as observational studies, registries, and clinical trials. The announcement also leaves room for other CER/PCOR-relevant approaches, which can include hybrid designs or emerging methods, so long as the program clearly links training content to improving the rigor and consistency of patient-centered and comparative effectiveness studies.

The FOA explicitly encourages the use of well-recognized methodological resources as teaching content. In particular, applicants may incorporate AHRQ-produced research methods guides and methodological standards adopted by the Patient-Centered Outcomes Research Institute (PCORI). This highlights AHRQ's intent to align training with established best practices and standards, improving consistency in how CER/PCOR is conducted and reported and helping trainees learn methods that funders and stakeholders recognize as credible.

From an administrative standpoint, this is a grant mechanism with no cost sharing or matching requirement. The estimated total funding for the opportunity was $2.5 million, with an award ceiling of $500,000 per award. The opportunity was posted on July 10, 2013, with an original (and final) application deadline of September 27, 2013, and an archive date of October 28, 2013, indicating the announcement is no longer open but remains a useful reference for similar future training initiatives.

Eligibility includes a range of organizations involved in education and research capacity building. Eligible applicants listed include public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, and Native American tribal organizations other than federally recognized tribal governments. The FOA also notes additional eligible applicants, including eligible agencies of the federal government. Foreign (non-U.S.) entities are explicitly not eligible to apply. The program is categorized under CFDA 93.226, Research on Healthcare Costs, Quality and Outcomes, reflecting its connection to improving evidence that informs healthcare decisions, quality, and value.

For reference and full details, the FOA was made available through the NIH grants guide website under the provided link (http://grants.nih.gov/grants/guide/rfa-files/RFA-HS-14-004.html). Technical issues accessing the full announcement were directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

Frequently Asked Questions (FAQs)

What is the title of this AHRQ grant opportunity?

The opportunity is titled "Researcher Training and Workforce Development in Methods and Standards for Conducting Patient Centered Outcomes Research Studies (R25)."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is RFA-HS-14-004.

Which federal agency released this funding opportunity?

The Agency for Healthcare Research and Quality (AHRQ) released this discretionary grant opportunity.

What is the main purpose of this grant program?

The program is designed to strengthen the national research workforce by supporting the creation of structured education and training programs that teach researchers how to plan, conduct, analyze, and evaluate high-quality comparative clinical effectiveness research (CER) and patient-centered outcomes research (PCOR).

What larger goal is AHRQ trying to achieve through this training program?

AHRQ aims to expand national capacity so more investigators and research teams can reliably apply accepted methodologies and methodological standards when generating real-world evidence that compares health interventions, services, or approaches to care.

What kinds of activities are funded under this FOA?

Funded projects are expected to develop, implement, and evaluate a structured education program focused specifically on CER/PCOR methods and standards.

Does the training program need to be tailored to a specific audience?

Yes. AHRQ is looking for education programs deliberately designed around the needs of a particular professional field, work environment, or defined researcher community, rather than a generic curriculum.

What settings does AHRQ consider relevant for these training models?

The FOA emphasizes practical, relevant training models for settings where CER/PCOR is performed, including academic institutions, health systems, research networks, and other applied research environments.

Is there a required structure for the education program?

Yes. The education program must be multi-component and include a progression of training levels.

What training levels must the program include?

Programs must include: (1) basic instruction for foundational knowledge, (2) advanced instruction for deeper methodological competence, and (3) experiential training that allows participants to apply CER/PCOR methods in practice.

What does AHRQ mean by "experiential training" in this FOA?

The FOA signals that AHRQ wants more than lectures or short courses. Experiential training should provide applied opportunities such as mentored projects, hands-on workshops, applied analyses, protocol development exercises, or similar activities that build competency and confidence in CER/PCOR approaches.

What research methods or study designs can the training cover?

The FOA allows broad coverage of research designs commonly used in CER/PCOR, including methods for designing and analyzing systematic reviews and technology assessments, as well as primary research approaches such as observational studies, registries, and clinical trials.

Can applicants include other or emerging CER/PCOR methods?

Yes. The announcement leaves room for other CER/PCOR-relevant approaches (including hybrid designs or emerging methods) as long as the training content is clearly linked to improving the rigor and consistency of patient-centered and comparative effectiveness studies.

Does the FOA recommend any specific methodological resources to use in teaching?

Yes. The FOA explicitly encourages incorporating well-recognized resources, including AHRQ-produced research methods guides and methodological standards adopted by the Patient-Centered Outcomes Research Institute (PCORI).

Why does the FOA emphasize AHRQ methods guides and PCORI methodological standards?

The emphasis reflects AHRQ's intent to align training with established best practices and recognized standards, improving consistency in how CER/PCOR is conducted and reported and helping trainees learn approaches that stakeholders consider credible.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement for this grant mechanism.

How much total funding was estimated for this opportunity?

The estimated total funding for the opportunity was $2.5 million.

What is the maximum award amount (award ceiling)?

The award ceiling was $500,000 per award.

When was this funding opportunity posted?

The opportunity was posted on July 10, 2013.

What was the application deadline?

The original (and final) application deadline was September 27, 2013.

Is this FOA still open for applications?

No. The archive date was October 28, 2013, which indicates the announcement is no longer open (though it may still be useful as a reference for similar future training initiatives).

Who is eligible to apply?

Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, and Native American tribal organizations other than federally recognized tribal governments. The FOA also notes additional eligible applicants, including eligible agencies of the federal government.

Are foreign (non-U.S.) entities eligible to apply?

No. Foreign (non-U.S.) entities are explicitly not eligible to apply.

What CFDA program is this opportunity associated with?

This program is categorized under CFDA 93.226, Research on Healthcare Costs, Quality and Outcomes.

Where can the full funding announcement be found?

The FOA was made available through the NIH grants guide website at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HS-14-004.html

Where were technical issues accessing the announcement directed?

Technical issues accessing the full announcement were directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

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