Opportunity Information: Apply for PAR 12 092
Apply for PAR 12 092
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Resource Access for the Bridging Interventional Development Gaps Program (X01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Feb 1, 2012 and posted on Feb 1, 2012.
- Applicants must submit their applications by Apr 3, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Small businesses Public housing authorities/Indian housing authorities State governments Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Public and State controlled institutions of higher education Independent school districts City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in theNIH Grants Policy Statement, are allowed.
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Opportunity Summary:
Resource Access for the Bridging Interventional Development Gaps Program (BrIDGs) (X01) is a National Institutes of Health (NIH) grant opportunity designed to help move promising therapeutic discoveries closer to the clinic by reducing a major practical barrier: the high cost of preclinical development. Many potential therapies stall after initial discovery because the studies and specialized development work needed to support an eventual clinical trial can be too expensive or technically demanding for academic labs, small organizations, or other research groups, especially when private investment is not available or comes too early with terms that do not fit the project. This FOA addresses that gap by offering access to government-funded contract resources, provided as in-kind services, so investigators can complete key preclinical development steps needed to advance a candidate therapeutic agent.
The core idea behind the program is that NIH can help "bridge" the space between early research and human testing by providing practical development support rather than direct cash for a typical research budget. Through the X01 mechanism, selected projects gain access to federally supported contractors and specialized capabilities that can be difficult to obtain otherwise. The focus is specifically on preclinical development of therapeutic agents, with the intent that the supported work will strengthen the evidence package and readiness needed to move toward clinical evaluation. By supporting this stage, BrIDGs aims to keep viable therapies moving forward when private sector resources are limited, and to encourage continued evaluation of agents that could improve standards of care across a wide range of diseases and disorders.
Administratively, this opportunity is a discretionary grant under NIH, with the Funding Opportunity Number PAR-12-092 and the title "Resource Access for the Bridging Interventional Development Gaps Program (X01)." It falls under the Health funding activity category and is associated with CFDA 93.310 (Trans-NIH Research Support). There is no cost sharing or matching requirement, reinforcing that the federal contribution is intended to remove financial friction at a difficult translational stage. The announcement was posted and created on February 1, 2012, with an original and current closing date of April 3, 2012, and it was archived on May 4, 2012.
Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include nonprofits (both with and without 501(c)(3) status), public and private institutions of higher education, small businesses, state and local governments (including county and city or township governments), special district governments, independent school districts, public housing authorities/Indian housing authorities, and tribal governments and organizations (including federally recognized tribal governments and other tribal entities). The FOA also explicitly includes a variety of institution types and community-focused organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. Importantly, foreign institutions and other non-U.S. entities are eligible to apply, and non-U.S. components of U.S. organizations may participate; foreign components are allowed consistent with the NIH Grants Policy Statement.
For applicants trying to understand what this opportunity offers in practical terms, the essential takeaway is that BrIDGs (X01) is meant to provide access to government-funded development resources that can help generate the preclinical data and development groundwork that often stands between a compelling scientific discovery and a clinically testable therapeutic candidate. The full announcement and details were made available through NIH at http://grants.nih.gov/grants/guide/pa-files/PAR-12-092.html. For technical issues accessing the announcement, NIH directed applicants to the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the BrIDGs (X01) grant opportunity?
Resource Access for the Bridging Interventional Development Gaps Program (BrIDGs) (X01) is a National Institutes of Health (NIH) funding opportunity designed to help move promising therapeutic discoveries closer to clinical testing by addressing a common barrier: the cost and complexity of preclinical development work needed to support an eventual clinical trial.
What problem is this program trying to solve?
Many potential therapies stall after early discovery because the next steps (specialized studies and development work needed to support human testing) can be too expensive or technically demanding for academic labs, small organizations, and other research groups. This is especially true when private investment is not available, or when it becomes available too early with terms that do not fit the project. BrIDGs is intended to reduce that practical translational gap.
What does BrIDGs (X01) provide to selected projects?
Rather than providing direct cash funding for a typical research budget, BrIDGs (X01) provides access to government-funded contract resources as in-kind services. Selected projects gain access to federally supported contractors and specialized capabilities to help complete key preclinical development steps.
Is this a standard research grant with a cash award?
No. The core idea described for BrIDGs (X01) is practical development support through resource access (in-kind services), not a traditional direct-funding research budget.
What stage of research does BrIDGs (X01) focus on?
This opportunity focuses specifically on preclinical development of therapeutic agents, aiming to strengthen the development and evidence package needed to move toward clinical evaluation.
What is the overall goal of providing these resources?
The intent is to help investigators generate the preclinical data and development groundwork that often stands between a compelling discovery and a clinically testable therapeutic candidate, so viable therapies can continue progressing when private sector resources are limited.
What funding mechanism is used for this opportunity?
The program uses the X01 mechanism and is described as a discretionary grant under NIH.
What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number is PAR-12-092.
What is the official title of this Funding Opportunity Announcement (FOA)?
The title is "Resource Access for the Bridging Interventional Development Gaps Program (X01)."
What funding activity category is this opportunity associated with?
It is listed under the Health funding activity category.
What CFDA number is associated with this opportunity?
The associated CFDA is 93.310 (Trans-NIH Research Support).
Is cost sharing or matching required?
No. The provided information states there is no cost sharing or matching requirement.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Examples listed include nonprofits (with or without 501(c)(3) status), public and private institutions of higher education, small businesses, and various government entities and specialized organizations.
Are nonprofits eligible, including those without 501(c)(3) status?
Yes. The eligibility list explicitly includes nonprofits both with and without 501(c)(3) status.
Are colleges and universities eligible?
Yes. Both public and private institutions of higher education are listed as eligible applicants.
Are small businesses eligible?
Yes. Small businesses are explicitly included in the eligibility list.
Are state and local governments eligible to apply?
Yes. The eligibility list includes state governments and local governments, including county and city or township governments.
Are special district governments and independent school districts eligible?
Yes. Special district governments and independent school districts are included in the eligibility list.
Are public housing authorities or Indian housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.
Are tribal governments and tribal organizations eligible?
Yes. Eligibility includes federally recognized tribal governments and other tribal entities, as well as tribal governments and organizations.
Does the FOA include specific categories such as HBCUs and Hispanic-serving Institutions?
Yes. The FOA explicitly includes institution types and community-focused organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities (TCCUs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly mentioned as included.
Are regional organizations and U.S. territories or possessions included?
Yes. The eligibility description includes regional organizations and U.S. territories or possessions.
Are foreign institutions eligible to apply?
Yes. The FOA states that foreign institutions and other non-U.S. entities are eligible to apply.
Can non-U.S. components of U.S. organizations participate?
Yes. Non-U.S. components of U.S. organizations may participate, and foreign components are allowed consistent with the NIH Grants Policy Statement.
When was this announcement posted?
The announcement was posted and created on February 1, 2012.
What were the application closing dates?
The original closing date and the current closing date listed are both April 3, 2012.
Is this opportunity still open?
No. The provided information states it was archived on May 4, 2012, and the closing date was April 3, 2012.
Where can applicants find the full announcement?
The full announcement is available through NIH at http://grants.nih.gov/grants/guide/pa-files/PAR-12-092.html.
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing the announcement, NIH directed applicants to contact the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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