Opportunity Information: Apply for PA 08 180
Apply for PA 08 180
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Resource Program Grants in Bioformatics (P41)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Dec 3, 2008 and posted on Dec 3, 2008.
- Applicants must submit their applications by Sep 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) County governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Small businesses Native American tribal governments (Federally recognized) For profit organizations other than small businesses Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) State governments Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Resource Program Grants in Bioinformatics (P41) opportunity (Funding Opportunity Number PA 08-180) is a National Institutes of Health grant run through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Its core goal is to keep important bioinformatics resources running and make them better over time, specifically resources that matter for research on embryonic development using animal models. In practical terms, NICHD is looking to support the continued operation, improvement, and broad dissemination of specialized databases, digital information resources, and software tools that are considered unique and especially valuable to the developmental biology community. The emphasis is not on starting small, short-term pilot tools, but on sustaining and advancing established or clearly needed resources that serve a wider user base and help enable research across many labs.
This funding uses the NIH P41 mechanism, which is designed for resource-focused programs rather than traditional hypothesis-driven research projects. A P41 generally supports infrastructure-like efforts such as maintaining a database, curating and integrating datasets, improving software functionality, strengthening documentation and user support, building dissemination pipelines, and ensuring that a resource remains accessible, reliable, and useful to the broader community. Because the underlying resources and user communities can be very different from one application to the next, NICHD notes that award size and project duration are expected to vary, and the total number of awards is not fixed in advance. Instead, the final number and amount of awards depend on the quality of applications received, their scope, the proposed timeframes, and the costs that are well-justified for running and improving the resource.
The scientific focus is explicitly tied to bioinformatics resources that support research using animal models of embryonic developmental processes. That framing signals that competitive applications should clearly connect the proposed database or tool to developmental biology needs such as embryo staging, gene expression and regulation during development, developmental pathways, phenotyping, imaging or lineage tracing datasets, genotype-to-phenotype relationships, or other data types that are central to understanding embryogenesis in model organisms. The opportunity also highlights dissemination, meaning applicants should expect to describe how users will access the resource, how updates will be delivered, how the community will be informed and trained, and what steps will be taken to maximize usability and uptake (for example, user documentation, help desks or user forums, APIs, data standards, interoperability, and long-term availability).
NICHD strongly encourages applicants to consult with the listed Scientific/Research Contact before submitting, with the intent of confirming that a proposed project matches the objectives of the funding announcement and aligns with NICHD program priorities. This is a common NIH expectation for resource grants, where program staff feedback can help applicants position the resource appropriately, clarify what aspects of “resource-ness” reviewers will expect (governance, sustainability, community need, metrics of use, and dissemination), and avoid proposing something outside the intended scope.
Eligibility is broad and includes many types of U.S.-based organizations that can credibly host and operate a national-level or widely used research resource. Eligible applicants include public and private institutions of higher education, nonprofits with and without 501(c)(3) status, for-profit organizations (including small businesses and other for-profits), state and local governments (state, county, city/township), independent school districts, special district governments, public housing authorities/Indian housing authorities, Native American tribal governments and organizations (federally recognized and other than federally recognized), and U.S. territories or possessions. The announcement also explicitly notes inclusion of organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, and eligible federal agencies. There is no cost-sharing or matching requirement listed for this opportunity.
Key administrative details from the posting include that it is categorized as a discretionary grant in the Health area (CFDA 93.865, Child Health and Human Development Extramural Research), and it was posted on December 3, 2008, with an original and current closing date of September 7, 2011, and an archive date of October 8, 2011. The full announcement was made available through the NIH grants guide (link provided in the posting). For technical problems accessing the announcement, the NIH Office of Extramural Research (OER) webmaster contact is provided.
Frequently Asked Questions (FAQs): Resource Program Grants in Bioinformatics (P41) - PA 08-180 (NICHD)
What is the name of this funding opportunity?
The opportunity is titled Resource Program Grants in Bioinformatics (P41).
What is the Funding Opportunity Number?
The Funding Opportunity Number is PA 08-180.
Which agency and institute run this grant?
This is a National Institutes of Health (NIH) grant run through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
What is the main goal of this P41 opportunity?
The core goal is to keep important bioinformatics resources running and improve them over time, specifically resources that support research on embryonic development using animal models.
What kinds of projects is NICHD looking to support?
NICHD is looking to support the continued operation, improvement, and broad dissemination of specialized resources such as:
- Specialized databases
- Digital information resources
- Software tools
These resources should be considered unique and especially valuable to the developmental biology community, and should serve a wider user base across many labs.
Is this funding meant for new pilot tools or short-term projects?
No. The emphasis is not on starting small, short-term pilot tools. The focus is on sustaining and advancing established or clearly needed resources that enable research broadly across the community.
What does it mean that this uses the NIH P41 mechanism?
The NIH P41 mechanism is designed for resource-focused programs rather than traditional hypothesis-driven research projects. In practice, it supports infrastructure-like work to keep a resource accessible, reliable, and useful for the broader community.
What types of activities can a P41 resource grant support under this announcement?
Based on the posting, supported activities can include:
- Maintaining database or software operations
- Curating and integrating datasets
- Improving software functionality over time
- Strengthening documentation and user support
- Building or improving dissemination pipelines
- Ensuring the resource remains accessible, reliable, and broadly useful
What scientific area must the proposed resource support?
The scientific focus is explicitly tied to bioinformatics resources that support research using animal models of embryonic developmental processes.
What kinds of developmental biology needs are highlighted as relevant?
Competitive applications should clearly connect the proposed resource to needs such as:
- Embryo staging
- Gene expression and regulation during development
- Developmental pathways
- Phenotyping
- Imaging or lineage tracing datasets
- Genotype-to-phenotype relationships
- Other data types central to understanding embryogenesis in model organisms
How important is dissemination in this opportunity?
Dissemination is a stated emphasis. Applicants should expect to describe how users will access the resource, how updates will be delivered, and how the community will be informed and trained to maximize usability and uptake.
What dissemination elements are mentioned in the posting?
The posting gives examples of dissemination and usability components, including:
- User documentation
- Help desks or user forums
- APIs
- Data standards
- Interoperability
- Long-term availability
Are award size and project duration fixed?
No. NICHD notes that award size and project duration are expected to vary because resources and user communities can differ substantially across applications.
Is the number of awards predetermined?
No. The total number of awards is not fixed in advance. The final number and amount of awards depend on the quality of applications received, their scope, proposed timeframes, and well-justified costs.
What factors affect the final award amount and number of awards?
According to the posting, the final number and amount of awards depend on:
- The quality of applications received
- The scope of the proposed resource work
- The proposed timeframe
- Costs that are well-justified for operating and improving the resource
Does NICHD encourage contacting program staff before submitting?
Yes. NICHD strongly encourages applicants to consult with the listed Scientific/Research Contact before submitting, to confirm fit with the objectives of the announcement and NICHD program priorities.
Why is pre-submission contact encouraged for this opportunity?
The posting notes that program staff feedback can help applicants confirm that the project is within scope and understand expectations typical of resource grants (for example, governance, sustainability, community need, metrics of use, and dissemination).
Who is eligible to apply?
Eligibility is broad and includes many types of U.S.-based organizations that can host and operate a national-level or widely used research resource. Eligible applicants include:
- Public and private institutions of higher education
- Nonprofits with and without 501(c)(3) status
- For-profit organizations (including small businesses and other for-profits)
- State and local governments (state, county, city/township)
- Independent school districts
- Special district governments
- Public housing authorities/Indian housing authorities
- Native American tribal governments and organizations (federally recognized and other than federally recognized)
- U.S. territories or possessions
- Regional organizations
- Faith-based or community-based organizations
- Eligible federal agencies
Are specific institution types explicitly included?
Yes. The announcement explicitly notes inclusion of organizations such as:
- Historically Black Colleges and Universities (HBCUs)
- Hispanic-Serving Institutions
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
Is cost sharing or matching required?
No. The posting states there is no cost-sharing or matching requirement listed for this opportunity.
How is this opportunity categorized administratively?
It is categorized as a discretionary grant in the Health area.
What CFDA number is associated with this grant?
The posting lists CFDA 93.865, Child Health and Human Development Extramural Research.
When was this opportunity posted?
The posting date is December 3, 2008.
What is the closing date for this opportunity?
The posting lists an original and current closing date of September 7, 2011.
When was this opportunity archived?
The archive date listed is October 8, 2011.
Where can applicants find the full announcement?
The posting indicates the full announcement was made available through the NIH grants guide (with a link provided in the posting).
Who should be contacted for technical problems accessing the announcement?
For technical problems accessing the announcement, the posting provides the contact for the NIH Office of Extramural Research (OER) webmaster.
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