Opportunity Information: Apply for PAR 13 253
Apply for PAR 13 253
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Resource Related Research Projects for Development of Animal Models and Related Materials (R24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351 Research Infrastructure Programs.
- This funding opportunity was created on Jun 28, 2013 and posted on Jun 28, 2013.
- Applicants must submit their applications by Sep 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities State governments Independent school districts County governments Private institutions of higher education For profit organizations other than small businesses Small businesses Native American tribal governments (Federally recognized) Special district governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH funding opportunity PAR 13 253, titled "Resource Related Research Projects for Development of Animal Models and Related Materials (R24)," supports grant applications that build or strengthen shared research resources centered on laboratory animal models. The core purpose is to fund resource-related research projects that develop new animal models of human disease, substantially improve existing models, or generate related materials and tools that make those models more useful to the broader research community. In parallel, the FOA also supports projects that improve the diagnosis, prevention, monitoring, or control of diseases that affect laboratory animals themselves, since healthier and better-characterized colonies directly improve the reliability of biomedical research.
A key requirement is that the animal model resource being developed must clearly align with the scientific missions of at least two different categorical NIH Institutes and Centers. In other words, the model or related materials should be broadly relevant across multiple NIH areas, not narrowly tailored to a single disease area or one Institute's priorities. Applications that mainly serve one NIH Institute or Center and only incidentally touch on the interests of others are considered nonresponsive to this FOA. The announcement gives a concrete example: a proposal focused exclusively on an animal model of cancer would not be appropriate if it does not genuinely address the interests of multiple Institutes and Centers.
This is a discretionary grant program under the NIH Research Infrastructure Programs (CFDA 93.351) using the R24 activity code, which is typically used for resource-related projects rather than standard hypothesis-driven research alone. The emphasis is on creating, enhancing, or rigorously characterizing animal models and associated materials in ways that others can use, reproduce, and build upon. Practically, this often means projects that generate well-documented model strains, establish standardized phenotyping or validation data, improve genetic backgrounds or husbandry practices, develop associated reagents or protocols, and generally increase the utility and accessibility of models that address important biomedical needs spanning multiple NIH domains.
Eligibility is broad and includes many types of U.S.-based organizations across the public, private, nonprofit, and academic sectors. Eligible applicants include nonprofit organizations (with or without 501(c)(3) status), public and private institutions of higher education, federal-recognized tribal governments and other tribal organizations, state and local governments (including counties, cities/townships, special districts), public housing authorities/Indian housing authorities, independent school districts, regional organizations, and for-profit entities (including small businesses and other-than-small businesses). The FOA also explicitly includes a range of institution types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and AANAPISIs, as well as faith-based and community-based organizations and U.S. territories or possessions. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible; however, foreign components as defined by the NIH Grants Policy Statement are allowed, which generally means specific foreign participation may be included when well justified and compliant with NIH policy.
The opportunity does not require cost sharing or matching funds. The announcement was posted on June 28, 2013, with an original and final closing date of September 7, 2016, and it was archived on October 8, 2016. Applicants seeking the full details were directed to the NIH Guide for Grants and Contracts listing (PAR 13 253) and to NIH Office of Extramural Research (OER) contacts for technical access issues.
In short, this FOA was designed to fund the development and improvement of broadly useful animal model resources and laboratory-animal disease control tools that serve more than one NIH Institute or Center, strengthening the infrastructure that multiple biomedical research communities rely on rather than supporting narrowly focused, single-Institute model development.
FAQs: NIH PAR 13 253 (R24) Resource-Related Research Projects for Development of Animal Models and Related Materials
What is the NIH funding opportunity PAR 13 253?
PAR 13 253 is an NIH Funding Opportunity Announcement (FOA) titled "Resource Related Research Projects for Development of Animal Models and Related Materials (R24)." It supports resource-related research projects that build or strengthen shared research resources centered on laboratory animal models and related tools and materials.
What is the main goal of this FOA?
The main goal is to fund projects that develop new animal models of human disease, substantially improve existing models, or produce related materials and tools that increase the usefulness, reliability, and accessibility of those models for the broader research community.
What kinds of projects are considered responsive to PAR 13 253?
Projects are considered responsive when they are clearly resource-focused and aimed at creating, enhancing, or rigorously characterizing animal model resources that others can use and build upon. Examples described in the opportunity include developing well-documented model strains, establishing standardized phenotyping or validation data, improving genetic backgrounds or husbandry practices, and developing associated reagents or protocols that increase model utility and accessibility.
Does this FOA support work related to diseases that affect laboratory animals?
Yes. In addition to supporting development and improvement of animal models of human disease, the FOA also supports projects that improve the diagnosis, prevention, monitoring, or control of diseases that affect laboratory animals. The rationale provided is that healthier and better-characterized colonies improve the reliability of biomedical research.
What does "resource-related research" mean in the context of an R24?
In this FOA, "resource-related research" emphasizes developing or improving shared research infrastructure rather than conducting standard hypothesis-driven research alone. The focus is on outputs that can be broadly used, reproduced, and adopted by other researchers, such as validated models, characterization datasets, standardized methods, and supporting materials that increase utility for multiple communities.
What is the activity code for this opportunity?
The activity code is R24, which is typically used for resource-related projects intended to support and strengthen research infrastructure.
Is this FOA tied to a specific NIH program classification?
Yes. It is described as a discretionary grant program under the NIH Research Infrastructure Programs with CFDA 93.351.
Is there a requirement that the animal model resource align with multiple NIH Institutes and Centers?
Yes. A key requirement is that the animal model resource (or related materials) must clearly align with the scientific missions of at least two different categorical NIH Institutes and Centers. The FOA stresses that the proposed resource should be broadly relevant across multiple NIH areas, not narrowly tailored to one Institute's priorities.
What happens if a project mainly serves one NIH Institute or Center?
Applications that mainly serve one NIH Institute or Center and only incidentally touch on the interests of others are considered nonresponsive to this FOA, based on the description provided.
Does the FOA provide an example of a nonresponsive project?
Yes. The FOA provides an example that a proposal focused exclusively on an animal model of cancer would not be appropriate if it does not genuinely address the interests of multiple Institutes and Centers.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S.-based organizations across public, private, nonprofit, academic, and for-profit sectors. Examples listed include nonprofit organizations (with or without 501(c)(3) status), public and private institutions of higher education, tribal governments and other tribal organizations, state and local governments, public housing authorities/Indian housing authorities, independent school districts, regional organizations, and for-profit entities (including small businesses and other-than-small businesses).
Are specific institution designations explicitly included as eligible?
Yes. The FOA explicitly includes institution types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and AANAPISIs. It also includes faith-based and community-based organizations, as well as U.S. territories or possessions.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply under this FOA, based on the eligibility information provided.
Are non-U.S. components of U.S. organizations eligible?
No. Non-U.S. components of U.S. organizations are not eligible, as stated in the opportunity summary provided.
Are any types of foreign participation allowed?
Yes. The FOA allows "foreign components" as defined by the NIH Grants Policy Statement. This generally means specific foreign participation may be included when well justified and compliant with NIH policy, even though foreign institutions themselves cannot apply as the applicant organization.
Is cost sharing or matching required?
No. The opportunity states that cost sharing or matching funds are not required.
When was this FOA posted and when did it close?
The announcement was posted on June 28, 2013. It had an original and final closing date of September 7, 2016, and it was archived on October 8, 2016.
Is this opportunity still open for applications?
No. Based on the provided dates (final closing date September 7, 2016, and archived October 8, 2016), this FOA is no longer open.
Where were applicants directed to find full details about PAR 13 253?
Applicants were directed to the NIH Guide for Grants and Contracts listing for PAR 13 253 for full details.
Who should applicants contact for technical access issues?
The FOA directed applicants to NIH Office of Extramural Research (OER) contacts for technical access issues.
What is the intended impact of funding animal model resources under this FOA?
The intended impact is to strengthen shared biomedical research infrastructure by producing broadly useful animal models and related materials, plus improved laboratory-animal disease control tools, thereby increasing reliability and utility for multiple NIH-relevant research communities rather than supporting narrowly focused, single-Institute model development.
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