Opportunity Information: Apply for RFA MH 14 140

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Revision Applications for Research on Assessing the Role of Stigma in HIV Prevention and Care (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research.
  • This funding opportunity was created on Feb 13, 2013 and posted on Feb 13, 2013.
  • Applicants must submit their applications by May 1, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments For profit organizations other than small businesses Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) County governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) State governments Small businesses City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

This NIH funding opportunity, titled "Revision Applications for Research on Assessing the Role of Stigma in HIV Prevention and Care (R01)," was released as a discretionary grant announcement designed to strengthen and extend existing, active NIH-supported research projects through revision applications (what used to be called competitive supplement applications). The central goal is to deepen the evidence base on how stigma affects HIV prevention and HIV care, and to support research that can translate into better uptake of prevention tools, stronger engagement in care, and improved health outcomes for people affected by HIV. The announcement is sponsored by the National Institutes of Health, with leadership and program interest coming from both the National Institute of Mental Health (NIMH) and the National Institute of Allergy and Infectious Diseases (NIAID), reflecting the fact that stigma is both a behavioral/social barrier and a factor that directly shapes infectious disease outcomes at the population level.

The FOA emphasizes four main research directions. First, it encourages projects that validate stigma measures, meaning work that improves the accuracy, reliability, and real-world usefulness of tools used to measure HIV-related stigma (and potentially related stigmas that intersect with HIV, such as stigma tied to sexual orientation, gender identity, substance use, sex work, or mental illness). This can include psychometric testing, cultural and linguistic adaptation, and assessment of whether measures perform consistently across different groups and settings. Second, it supports research examining how HIV-associated stigma influences key steps along the prevention and care continua. On the prevention side, this can include willingness to seek testing, accept and adhere to biomedical prevention strategies, disclose risk, or access prevention services. On the care side, it can involve linkage to care, retention, medication adherence, viral suppression, and broader quality-of-life outcomes. Third, the FOA highlights stigma reduction as an outcome in studies that are already testing interventions primarily aimed at prevention or care. In other words, if a parent study is running an intervention to improve HIV-related outcomes, the revision could add aims that assess whether stigma decreases as part of the intervention’s effects, how that change happens, and whether stigma reduction helps explain improvements in prevention or care outcomes. Fourth, it invites pilot testing of novel interventions specifically designed to reduce stigma, supporting early-stage testing that can establish feasibility, acceptability, preliminary effectiveness, and implementation considerations.

From an administrative standpoint, this is an R01 grant mechanism and is categorized under health research funding. The related CFDA numbers listed are 93.242 (Mental Health Research Grants), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research), which signals the cross-cutting nature of the work and the likely relevance to both behavioral science and infectious disease research portfolios. The opportunity does not require cost sharing or matching funds, which can reduce barriers for organizations that might not have discretionary resources to contribute financially to the project.

In terms of who can apply, the eligibility list is broad and includes many types of domestic and international organizations. Eligible applicants include public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), for-profit organizations (other than small businesses, though small businesses are also explicitly listed as eligible), and various government entities such as state governments, county governments, city or township governments, special district governments, and independent school districts. The FOA also explicitly notes eligibility for a range of mission-specific and community-connected institutions and organizations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), and faith-based or community-based organizations. Importantly, non-U.S. entities are eligible as well: foreign organizations and foreign institutions can apply, non-domestic components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed. That structure reflects an understanding that HIV-related stigma is a global challenge and that innovation and evidence can come from diverse cultural and health system contexts.

The funding parameters listed include an award ceiling of $200,000, which suggests a relatively contained budget level aligned with revision scope rather than a full-scale new R01 project. The timeline information shows the FOA was posted and created on February 13, 2013, with an original and current closing date of May 1, 2013, and an archive date of June 1, 2013, meaning the announcement is no longer active but remains a useful reference point for the kinds of stigma-focused HIV research priorities NIH has supported through revisions. For applicants at the time, this would have meant proposing work that clearly builds on and complements an already-funded parent grant, adding targeted aims that fit the stigma focus without drifting into a wholly separate project.

Overall, the opportunity is best understood as NIH support for sharpening measurement, clarifying causal pathways, and testing practical strategies related to stigma in HIV. It encourages research that treats stigma not as a vague background issue but as a measurable, modifiable determinant of whether prevention and treatment efforts succeed. The full announcement and details were provided through the NIH grants website under Funding Opportunity Number RFA-MH-14-140, with support contacts routed through the NIH Office of Extramural Research (OER) webmaster for access or technical linking issues.

Frequently Asked Questions (FAQs)

What is the title of this NIH funding opportunity?

The opportunity is titled "Revision Applications for Research on Assessing the Role of Stigma in HIV Prevention and Care (R01)."

What type of application is this FOA seeking?

This announcement is for revision applications to strengthen and extend existing, active NIH-supported research projects. These were previously referred to as competitive supplement applications.

What is the main purpose of this funding opportunity?

The central goal is to deepen the evidence base on how stigma affects HIV prevention and HIV care, and to support research that can translate into better uptake of prevention tools, stronger engagement in care, and improved health outcomes for people affected by HIV.

Which NIH institutes are connected to this opportunity?

The opportunity is sponsored by the National Institutes of Health (NIH), with leadership and program interest from the National Institute of Mental Health (NIMH) and the National Institute of Allergy and Infectious Diseases (NIAID).

What grant mechanism does this opportunity use?

This opportunity uses the R01 grant mechanism.

What research areas does the FOA emphasize?

The FOA emphasizes four main research directions: (1) validating stigma measures; (2) examining how HIV-associated stigma influences steps along HIV prevention and care continua; (3) adding stigma reduction as an outcome to existing prevention or care interventions being tested in a parent study; and (4) pilot testing novel interventions specifically designed to reduce stigma.

What does "validating stigma measures" mean in the context of this FOA?

It refers to research that improves the accuracy, reliability, and real-world usefulness of tools used to measure HIV-related stigma (and potentially intersecting stigmas). The FOA notes examples such as psychometric testing, cultural and linguistic adaptation, and assessing whether measures perform consistently across different groups and settings.

What kinds of intersecting stigmas may be relevant under this FOA?

The FOA notes that, in addition to HIV-related stigma, projects may consider related stigmas that intersect with HIV, such as stigma tied to sexual orientation, gender identity, substance use, sex work, or mental illness.

How does the FOA link stigma to the HIV prevention continuum?

On the prevention side, the FOA highlights potential stigma impacts on willingness to seek testing, accept and adhere to biomedical prevention strategies, disclose risk, or access prevention services.

How does the FOA link stigma to the HIV care continuum?

On the care side, the FOA highlights potential stigma impacts on linkage to care, retention, medication adherence, viral suppression, and broader quality-of-life outcomes.

Can a revision application add stigma outcomes to an existing intervention study?

Yes. The FOA specifically highlights stigma reduction as an outcome that can be added to studies already testing interventions primarily aimed at prevention or care, including assessing whether stigma decreases, how that change happens, and whether stigma reduction helps explain improvements in prevention or care outcomes.

Does the FOA support testing new stigma-reduction interventions?

Yes. The FOA invites pilot testing of novel interventions specifically designed to reduce stigma, including early-stage testing to establish feasibility, acceptability, preliminary effectiveness, and implementation considerations.

Is cost sharing or matching required?

No. The opportunity does not require cost sharing or matching funds.

What are the related CFDA numbers listed for this opportunity?

The related CFDA numbers listed are 93.242 (Mental Health Research Grants), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research).

What does the presence of multiple CFDA numbers suggest?

Based on the FOA description, the multiple CFDA numbers signal the cross-cutting nature of the work and its relevance to both behavioral science and infectious disease research portfolios.

Who is eligible to apply?

Eligibility is broad and includes public and private institutions of higher education; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (including small businesses, which are explicitly listed as eligible); and government entities such as state, county, city or township governments, special district governments, and independent school districts.

Are community-connected and mission-specific institutions included as eligible applicants?

Yes. The FOA explicitly notes eligibility for organizations and institutions such as HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), and faith-based or community-based organizations.

Are international (non-U.S.) organizations eligible to apply?

Yes. The FOA states that foreign organizations and foreign institutions can apply. It also notes that non-domestic components of U.S. organizations are eligible and that foreign components (as defined by NIH policy) are allowed.

What is the award ceiling listed for this opportunity?

The funding parameters list an award ceiling of $200,000.

What does the $200,000 ceiling imply about the scope?

Based on the FOA description, the ceiling suggests a relatively contained budget level aligned with the scope of a revision (adding targeted aims to an active parent grant) rather than proposing an entirely new, full-scale R01 project.

When was the FOA posted and when did it close?

The FOA was posted/created on February 13, 2013. The original and current closing date is listed as May 1, 2013, and the archive date is June 1, 2013.

Is this funding opportunity still active?

No. The FOA is archived (archive date June 1, 2013) and is no longer active.

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number is RFA-MH-14-140.

What kind of project should a revision application propose under this FOA?

Based on the FOA description, an application would be expected to build on and complement an already-funded parent grant by adding targeted aims that fit the stigma focus, rather than drifting into a wholly separate project.

Where were the full announcement details made available?

The FOA indicates the full announcement and details were provided through the NIH grants website.

Who is listed for support or technical linking issues?

Support contacts for access or technical linking issues are routed through the NIH Office of Extramural Research (OER) webmaster.

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