Opportunity Information: Apply for PAR 13 177
Apply for PAR 13 177
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Revision Applications to R01 Awards for Research on Imaging and Biomarkers for Early Cancer Detection (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.394 Cancer Detection and Diagnosis Research.
- This funding opportunity was created on Apr 11, 2013 and posted on Apr 11, 2013.
- Applicants must submit their applications by Dec 11, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- Eligible applicants include: Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities State governments City or township governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
This NIH funding opportunity (PAR-13-177) supports revision applications to active NIH R01 awards that want to expand the scope of an already-funded cancer research project by adding one or more new Specific Aims. The central idea is not to start a brand-new standalone R01, but to build on an existing, currently active R01 by proposing additional work that meaningfully extends what is already underway. The scientific focus is on improving cancer screening, earlier detection, and diagnosis by combining imaging and biomarker strategies in a more integrated way than is typically done with either approach alone.
The FOA is aimed at projects that bring together multi-modality imaging approaches and multiplexed biomarker methodologies. In practical terms, this means revision proposals should emphasize how imaging technologies (for example, strategies that leverage more than one imaging modality or integrate imaging data streams) can be paired with biomarker measurements (for example, panels of biomarkers assessed simultaneously, rather than a single marker) to create better early detection tools or diagnostic workflows. The expectation is that applicants will propose new aims that directly test, refine, validate, or otherwise advance combined imaging-plus-biomarker approaches that could improve sensitivity, specificity, risk stratification, or clinical decision-making in early cancer detection contexts.
Administratively, this is a discretionary grant opportunity using the NIH R01 mechanism as a revision to an existing award. The funding activity category is listed under Education/Health, and the CFDA number provided is 93.394 (Cancer Detection and Diagnosis Research). The announcement explicitly states there is no cost-sharing or matching requirement. A listed award ceiling is $150,000, which signals an upper bound for what NIH expected to provide for the revision component (applicants would still need to align budgets with NIH rules for revisions and with the scope and justification for the added aims).
Eligibility is broad and includes many common applicant types across academia, government, nonprofit, and industry, so long as the applicant has an active NIH R01 that can be revised. Eligible applicant organizations include public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), local and state governments, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, independent school districts, and special district governments. The FOA also includes a wide set of explicitly named eligible categories such as HBCUs, Hispanic-serving institutions, AANAPISI institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based or community-based organizations, and eligible federal agencies. Importantly, foreign participation is allowed: non-U.S. organizations (foreign organizations and foreign institutions) may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are permitted.
The key dates show the opportunity was posted and created on April 11, 2013, with an original and current closing date of December 11, 2015, and an archive date of January 11, 2016. That timing indicates this specific FOA is no longer open, but it remains a useful reference point for understanding how NIH structures revision opportunities tied to active R01 awards, especially in the early detection space where integrated imaging and biomarker approaches are a recurring programmatic priority.
For applicants seeking the full original announcement text and any related NIH instructions, the FOA points to the NIH Grants Guide page at http://grants.nih.gov/grants/guide/pa-files/PAR-13-177.html. For technical access issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is NIH PAR-13-177?
PAR-13-177 is an NIH funding opportunity announcement (FOA) that supports revision applications to active NIH R01 awards. It is designed for projects that want to expand the scope of an already-funded cancer research project by adding one or more new Specific Aims, rather than proposing an entirely new standalone R01.
Is this opportunity for new R01 applications or only revisions?
This FOA is specifically for revisions to existing, currently active NIH R01 awards. The intent is to build on an existing funded R01 by proposing additional work that meaningfully extends what is already underway.
What is the scientific purpose of this FOA?
The scientific focus is on improving cancer screening, earlier detection, and diagnosis by combining imaging and biomarker strategies in a more integrated way than is typically done when either approach is used alone.
What kinds of approaches does the FOA encourage?
The FOA encourages projects that bring together multi-modality imaging approaches and multiplexed biomarker methodologies. In practical terms, applicants are expected to propose new aims that integrate imaging technologies with biomarker measurements to create better early detection tools or diagnostic workflows.
What does "multi-modality imaging" mean in the context of this FOA?
Within the scope described, multi-modality imaging refers to strategies that leverage more than one imaging modality or that integrate imaging data streams as part of a combined approach aimed at earlier cancer detection or improved diagnosis.
What does "multiplexed biomarker methodologies" mean in the context of this FOA?
In the context provided, multiplexed biomarker methodologies refer to measuring panels of biomarkers assessed simultaneously, rather than relying on a single biomarker, as part of an integrated imaging-plus-biomarker approach.
What types of new Specific Aims are expected for a revision application?
The FOA emphasizes new aims that directly test, refine, validate, or otherwise advance combined imaging-plus-biomarker approaches. The added work should be positioned to improve outcomes like sensitivity, specificity, risk stratification, or clinical decision-making in early cancer detection contexts.
Does the FOA support projects focused on early cancer detection and diagnosis?
Yes. The stated focus is on improving cancer screening, earlier detection, and diagnosis through integrated imaging and biomarker strategies.
What grant mechanism is used for this opportunity?
The opportunity uses the NIH R01 mechanism, specifically as a revision to an existing award.
Is this a discretionary grant opportunity?
Yes. The FOA is described as a discretionary grant opportunity.
What is the funding activity category listed for this FOA?
The funding activity category is listed under Education/Health.
What CFDA number is associated with this FOA?
The CFDA number provided is 93.394, labeled as Cancer Detection and Diagnosis Research.
Is cost-sharing or matching required?
No. The announcement explicitly states there is no cost-sharing or matching requirement.
What is the maximum award amount mentioned for the revision component?
The FOA lists an award ceiling of $150,000, indicating an upper bound for what NIH expected to provide for the revision component, with budgets needing to align with NIH rules for revisions and the justification for the added aims.
Who is eligible to apply?
Eligibility is broad across academia, government, nonprofit, and industry, as long as the applicant organization has an active NIH R01 that can be revised under this FOA.
What types of organizations are eligible?
Eligible applicant organizations include:
- Public and private institutions of higher education
- Nonprofits (including 501(c)(3) and certain non-501(c)(3) entities)
- For-profit organizations (including small businesses and other for-profits)
- Local and state governments
- Tribal governments and tribal organizations
- Public housing authorities/Indian housing authorities
- Independent school districts
- Special district governments
- Eligible federal agencies
Are minority-serving institutions explicitly included as eligible?
Yes. The FOA explicitly names categories such as HBCUs, Hispanic-serving institutions, AANAPISI institutions, tribally controlled colleges and universities, and Alaska Native and Native Hawaiian serving institutions among eligible organization types.
Are faith-based or community-based organizations eligible?
Yes. The FOA explicitly includes faith-based and community-based organizations among eligible categories.
Is foreign participation allowed?
Yes. Foreign participation is allowed. The FOA states that non-U.S. organizations (foreign organizations and foreign institutions) may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are permitted.
When was this FOA posted and when did it close?
The opportunity was posted and created on April 11, 2013. The original and current closing date listed is December 11, 2015, and the archive date is January 11, 2016.
Is PAR-13-177 still open for applications?
No. Based on the closing date (December 11, 2015) and archive date (January 11, 2016), this specific FOA is no longer open.
Where can applicants find the full original FOA text?
The FOA points to the NIH Grants Guide page here: http://grants.nih.gov/grants/guide/pa-files/PAR-13-177.html.
Who should be contacted for technical access issues related to the FOA?
For technical access issues, the listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Browse more opportunities from the same category: Education Health
Next opportunity: Revision Applications to P50 Awards for Research on Imaging and Biomarkers for Early Cancer Detection (P50)
Previous opportunity: Imaging and Biomarkers for Early Cancer Detection (R01)
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