Opportunity Information: Apply for PAR 12 289

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Revisions for Early Stage Development of Informatics Technology (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.396 Cancer Biology Research.
  • This funding opportunity was created on Sep 20, 2012 and posted on Sep 19, 2012.
  • Applicants must submit their applications by Jun 18, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $150,000.00 in funding.
  • Eligible applicants include: County governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments City or township governments State governments Small businesses Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The grant opportunity titled "Revisions for Early Stage Development of Informatics Technology (U01)" (Funding Opportunity Number PAR-12-289) is a National Institutes of Health announcement issued through the National Cancer Institute (NCI). It is specifically designed to solicit revision applications (previously called competing revisions) from projects that already hold active NCI U01 cooperative agreement awards. In other words, this is not a general open call for brand-new standalone projects; it is aimed at current NCI U01 awardees who want to propose an expanded or modified scope of work that stays aligned with their existing award while pushing forward additional early-stage informatics technology development.

The central purpose of the announcement is to support the early-stage development of enabling informatics technologies that improve how cancer research data and knowledge are acquired, managed, analyzed, and shared. The focus is on building new computational and informatics approaches that make it easier for researchers to move from raw data to useful knowledge and, ultimately, to practices that can influence clinical care. The announcement sits within the NCI Informatics Technology for Cancer Research (ITCR) Initiative, which emphasizes practical, innovative technology creation that can accelerate progress across many areas of cancer research.

A key expectation is interdisciplinary collaboration. The FOA is framed to encourage teams that combine expertise across domains such as cancer biology, clinical research, computer science, software engineering, informatics, and related quantitative fields. The overall intent is to promote tools, methods, and platforms that are more than incremental improvements, and that can address persistent bottlenecks in data handling and knowledge generation in cancer research. Importantly, the announcement draws a clear line around what is and is not a good fit: proposals that only conduct data processing and analysis, or that only present mathematical or statistical modeling work, are considered nonresponsive if they do not include genuine new technology development. The emphasis is on creating enabling technology rather than simply applying existing methods to datasets.

From an administrative standpoint, this is a discretionary funding opportunity using the cooperative agreement mechanism (U01). Cooperative agreements typically involve substantial scientific or programmatic involvement from the funding agency compared with standard grants, which often means awardees can expect ongoing coordination with NCI program staff around milestones, direction, and project oversight consistent with the ITCR program model. The activity category is listed under education and health, and the CFDA number associated with the opportunity is 93.396 (Cancer Biology Research). There is no cost sharing or matching requirement stated for applicants.

The opportunity was posted on September 19, 2012, created on September 20, 2012, and had an original and current closing date of June 18, 2015, with an archive date of July 19, 2015, indicating that it is no longer active. The listed award ceiling is $150,000, which provides a sense of the maximum funding level expected under this specific revision opportunity (though actual awards can vary based on NCI policies, budgets, and the scope of the requested revision).

Eligibility is broad in terms of institution types, but the practical eligibility constraint is that applicants must be submitting a revision to an already funded NCI U01 cooperative agreement project in the relevant area. The eligible applicant types include a wide range of public and private entities, such as state and local governments, tribal governments and tribal organizations, public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) organizations), for-profit organizations (including small businesses), independent school districts, public housing authorities, and other organizations as permitted under NIH rules. The announcement also explicitly notes additional eligible groups such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, AANAPISIs, faith-based or community-based organizations, U.S. territories or possessions, regional organizations, and even non-U.S. entities (foreign organizations), as well as eligible federal agencies.

For applicants seeking more details, the full announcement was hosted through the NIH Grants Guide at the provided link: http://grants.nih.gov/grants/guide/pa-files/PAR-12-289.html. The contact information supplied is oriented to technical access and linking issues, directing users to the NIH Office of Extramural Research (OER) webmaster email (FBOWebmaster@OD.NIH.GOV) for help accessing the announcement online.

Frequently Asked Questions (FAQs)

What is the official title and funding opportunity number for this grant?

The opportunity is titled "Revisions for Early Stage Development of Informatics Technology (U01)" and the Funding Opportunity Number (FON) is PAR-12-289.

Which federal agency and NIH institute issued this announcement?

This is a National Institutes of Health (NIH) announcement issued through the National Cancer Institute (NCI).

What type of application is being solicited under this opportunity?

This announcement is designed to solicit revision applications (previously called competing revisions) to existing awards, rather than applications for entirely new standalone projects.

Who is eligible to apply in practical terms?

In practical terms, eligibility is limited to applicants who already hold an active NCI U01 cooperative agreement award and are submitting a revision to that existing project.

Is this opportunity open to brand-new projects without an existing NCI U01 award?

No. It is not described as a general open call for new standalone projects. It specifically targets revisions to active NCI U01 cooperative agreement awards.

What is the main purpose of the funding opportunity?

The purpose is to support early-stage development of enabling informatics technologies that improve how cancer research data and knowledge are acquired, managed, analyzed, and shared, with the broader goal of helping researchers move from raw data to useful knowledge and potentially to practices that can influence clinical care.

What program initiative is this opportunity associated with?

The announcement sits within the NCI Informatics Technology for Cancer Research (ITCR) Initiative, which emphasizes practical and innovative technology creation to accelerate progress across cancer research.

What kinds of work are considered a strong fit?

A strong fit is described as work that develops new computational and informatics approaches, tools, methods, or platforms that address bottlenecks in data handling and knowledge generation in cancer research and that represent more than incremental improvements.

What kinds of applications are considered nonresponsive?

Applications are described as nonresponsive if they only conduct data processing and analysis or only present mathematical or statistical modeling work without genuine new technology development. The emphasis is on creating enabling technology rather than simply applying existing methods to datasets.

Does the announcement encourage interdisciplinary teams?

Yes. It is framed to encourage interdisciplinary collaboration, including teams combining expertise such as cancer biology, clinical research, computer science, software engineering, informatics, and related quantitative fields.

What funding mechanism is used (grant vs. cooperative agreement)?

The mechanism is a cooperative agreement (U01). This generally implies substantial scientific or programmatic involvement from the funding agency compared with standard grants.

What does the cooperative agreement (U01) structure imply for awardees?

Based on the description, awardees can expect ongoing coordination with NCI program staff around milestones, direction, and project oversight consistent with the ITCR program model.

What is the maximum award amount listed for this revision opportunity?

The listed award ceiling is $150,000, which indicates the maximum funding level expected under this specific revision opportunity, although actual awards can vary based on NCI policies, budgets, and the scope of the requested revision.

Is cost sharing or matching required?

No cost sharing or matching requirement is stated for applicants.

What is the CFDA number associated with this opportunity?

The CFDA number listed is 93.396 (Cancer Biology Research).

How is the activity category described?

The activity category is listed under education and health.

When was the opportunity posted and when did it close?

It was posted on September 19, 2012, created on September 20, 2012, and the original and current closing date is listed as June 18, 2015. The archive date is July 19, 2015.

Is this funding opportunity still active?

No. The closing and archive dates indicate it is no longer active.

What types of organizations are listed as eligible applicant types?

The announcement lists a wide range of eligible organization types, including state and local governments, tribal governments and tribal organizations, public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) organizations), for-profit organizations (including small businesses), independent school districts, public housing authorities, and other organizations as permitted under NIH rules.

Are any specific institution categories explicitly called out as eligible?

Yes. It explicitly notes eligibility for groups such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, AANAPISIs, faith-based or community-based organizations, U.S. territories or possessions, regional organizations, non-U.S. entities (foreign organizations), and eligible federal agencies.

Where can applicants find the full announcement?

The full announcement was hosted in the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-12-289.html.

Who should be contacted for technical access or linking issues related to the online announcement?

The contact provided for help accessing the announcement online (technical access and linking issues) is the NIH Office of Extramural Research (OER) webmaster email: FBOWebmaster@OD.NIH.GOV.

What is the key constraint to keep in mind even though many institution types are listed as eligible?

Even though eligibility is broad by institution type, the key constraint is that the application must be a revision to an already funded, active NCI U01 cooperative agreement project in the relevant area.

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