Opportunity Information: Apply for PA 16 310

  • The HHS-NIH11 in the education, environment, health sector is offering a public funding opportunity titled "Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.233, 93.273, 93.279, 93.361, 93.398, 93.837, 93.838, 93.839, 93.840, 93.846, 93.859, 93.866,.
  • This funding opportunity was created on Jun 03, 2016 and posted on Jun 03, 2016.
  • Applicants must submit their applications by May 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:

The Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33), funding opportunity number PA-16-310, is an NIH fellowship program designed to support experienced scientists who are at a stage in their careers where additional, structured research training would meaningfully redirect or expand their independent research trajectory. Rather than functioning like a traditional research project grant that primarily funds a set of experiments, this mechanism is framed as an advanced training award: it is meant for established investigators who want to make a significant shift in research direction, step into a new interdisciplinary area, or gain specific new technical or conceptual capabilities that will strengthen their long-term contributions in biomedical, behavioral, clinical, or related research areas that align with the missions of participating NIH Institutes and Centers.

In practical terms, the program targets senior or well-established researchers who can demonstrate that they already have substantial research experience but need a period of mentored training to acquire expertise they do not currently possess. The central idea is career development through immersion in a new environment, method, or field. Examples of the kind of change this fellowship is intended to support include retraining to use a new methodology (for instance, advanced computational approaches, new imaging platforms, or specialized clinical research methods), moving into a substantially different disease area or scientific discipline, or building a new line of inquiry that requires mentorship and a structured plan before it can be sustained independently. The fellowship is therefore especially relevant when an investigator can clearly justify why the proposed training is necessary, why it cannot be obtained as effectively through short courses or collaborations alone, and how it will lead to a credible, longer-term research direction.

The opportunity is administered by the U.S. Department of Health and Human Services through the National Institutes of Health (agency listed as HHS-NIH11). It is categorized as a discretionary grant and is listed under funding activity areas that include education, environment, and health. The listing references multiple CFDA numbers (now generally referred to under Assistance Listing numbers) associated with different NIH institutes and programs, reflecting that the fellowship aligns with a broad range of NIH mission areas rather than being confined to a single institute.

Eligibility, as presented in the source data, spans a wide range of organization types that can serve as applicant or sponsoring institutions, including public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (excluding small businesses and including small businesses as well), state and local governments, federally recognized tribal governments, tribal organizations, independent school districts, special district governments, and public housing authorities/Indian housing authorities. In the context of an NIH individual fellowship, this broad institutional eligibility typically matters because the fellow conducts the training at an eligible sponsoring institution with appropriate research infrastructure and mentorship, and administrative support for managing the award. The applicant is the individual scientist seeking the fellowship, but the application is usually submitted with the backing of the host institution and proposed sponsor, with a defined training environment and plan.

Key dates in the provided notice show that the opportunity was posted on June 3, 2016, created on June 3, 2016, and had a closing date of May 7, 2019 (with the original and current closing dates both listed as May 7, 2019). The source data does not specify an award ceiling or the expected number of awards, which often indicates that award size and volume depend on NIH institute participation, annual appropriations, and the number and quality of applications received.

Overall, the Parent F33 is best understood as a targeted NIH investment in high-impact retraining for seasoned investigators: it supports a structured, mentored training period intended to add new skills and perspectives that can substantially reshape an established scientist's independent research program in ways that advance NIH-relevant fields.

Frequently Asked Questions (FAQs): NIH NRSA Individual Senior Fellowship (Parent F33) - PA-16-310

What is the Ruth L. Kirschstein NRSA Individual Senior Fellowship (Parent F33)?

The Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) is an NIH fellowship program intended to support experienced, well-established scientists who need a structured period of mentored research training to meaningfully redirect or expand their independent research careers.

What is the funding opportunity number for this program?

The funding opportunity number is PA-16-310.

Who administers this fellowship opportunity?

This opportunity is administered by the U.S. Department of Health and Human Services through the National Institutes of Health (listed as HHS-NIH11).

Is the F33 a research project grant?

No. Based on the description provided, the F33 is framed as an advanced training award rather than a traditional research project grant that primarily funds a defined set of experiments. The emphasis is on mentored training and career development through acquiring new expertise.

What is the main purpose of the Parent F33 fellowship?

The main purpose is to provide experienced investigators with a mentored, structured training period to gain capabilities they do not currently possess, in order to substantially redirect or expand their independent research trajectory in NIH-relevant areas.

Who is this fellowship intended for?

It is intended for senior or well-established researchers who already have substantial research experience but need additional mentored training to acquire new technical, conceptual, or interdisciplinary expertise that they cannot obtain as effectively through short courses or collaborations alone.

What kinds of career changes or training goals does this fellowship support?

Examples described include retraining to use a new methodology (such as advanced computational approaches, new imaging platforms, or specialized clinical research methods), moving into a substantially different disease area or scientific discipline, or building a new line of inquiry that requires mentorship and a structured plan before it can be sustained independently.

What research areas does the Parent F33 align with?

The fellowship is intended to support biomedical, behavioral, clinical, or related research areas that align with the missions of participating NIH Institutes and Centers.

Why does the program emphasize mentored, structured training?

Because the core idea is career development through immersion in a new environment, method, or field. The program is designed for cases where the applicant can justify that a meaningful shift in research direction requires a planned, mentored training period.

What is meant by a "significant shift" in research direction?

Based on the description, a significant shift could include stepping into a new interdisciplinary area, changing to a substantially different field or disease area, or adding specialized capabilities that reshape an established research program and create a credible longer-term direction.

What type of funding is this categorized as?

It is categorized as a discretionary grant.

What funding activity areas are associated with this opportunity?

The listing includes education, environment, and health as funding activity areas.

Does the listing reference Assistance Listing (CFDA) numbers?

Yes. The description notes that multiple CFDA numbers (now generally referred to as Assistance Listing numbers) are referenced, reflecting alignment with a broad range of NIH institute and program mission areas.

Who can serve as the applicant or sponsoring institution according to the source data?

The source data lists a wide range of eligible organization types, including: public and private institutions of higher education; nonprofits (with or without 501(c)(3) status); for-profit organizations (including small businesses and excluding small businesses as well); state and local governments; federally recognized tribal governments; tribal organizations; independent school districts; special district governments; and public housing authorities/Indian housing authorities.

In practical terms, how does institutional eligibility matter for an NIH individual fellowship like this?

In the context described, institutional eligibility matters because the fellow conducts the training at an eligible sponsoring (host) institution that can provide appropriate research infrastructure, mentorship, and administrative support for managing the award. The applicant is the individual scientist, but the application is typically submitted with the backing of the host institution and a proposed sponsor as part of a defined training plan and environment.

Is an award ceiling listed in the provided information?

No. The source data does not specify an award ceiling.

Is the expected number of awards listed in the provided information?

No. The source data does not specify the expected number of awards.

What does it mean that award size and volume may not be specified here?

Based on the provided description, it suggests award size and volume may depend on NIH institute participation, annual appropriations, and the number and quality of applications received.

When was this opportunity posted and created?

The opportunity was posted on June 3, 2016, and created on June 3, 2016.

What was the closing date for this opportunity according to the notice?

The closing date listed is May 7, 2019 (with both the original and current closing dates shown as May 7, 2019).

What is the best overall way to understand the Parent F33 based on the description provided?

It is best understood as an NIH investment in high-impact retraining for seasoned investigators, supporting a structured, mentored training period intended to add new skills and perspectives that can substantially reshape an established scientist's independent research program in NIH-relevant fields.

Browse more opportunities from the same agency: HHS-NIH11

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Next opportunity: Ruth L. Kirschstein National Research Service Award (NRSA) Fellowship for Students at Institutions With NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

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